• The Korean Journal of Physiology and Pharmacology
• /
• 제9권3호
• /
• pp.179-186
• /
• 2005

Whole bee venom (WBV) and its major component, melittin, have been reported to induce long-lasting spontaneous flinchings and hyperalgesia. The current study was designed to elucidate the peripheral and spinal mechanisms of N-methyl-D-aspartate (NMDA) and non-NMDA receptors by which intraplantar (i.pl.) injection of WBV and melittin induced nociceptive responses. Changes in mechanical threshold and flinching behaviors were measured after the injection of WBV (0.04 mg or 0.1 mg/paw) and melittin (0.02 mg or 0.05 mg/paw) into the mid-plantar area of a rat hindpaw. MK-801 and CNQX (6-cyano-7-nitroquinoxaline-2,3-dione disodium) were administered intrathecally (i.t. $10{\mu}g$) or i.pl.($15{\mu}g$) 15 min before or i.t. 60 min after i.pl. WBV and melittin injection. Intrathecal pre- and postadministration of MK-801 and CNQX significantly attenuated the ability of high dose WBV and melittin to reduce paw withdrawal threshold (PWT). In the rat injected with low dose, but not high dose, of WBV and melittin, i.pl. injection of MK-801 effectively suppressed the decrease of PWTs only at the later time-points, but the inhibitory effect of CNQX (i.pl.) was significant at all time-point after the injection of low dose melittin. High dose WBV- and melittin-induced spontaneous flinchings were significantly suppressed by i.t. administration of MK-801 and CNQX, and low dose WBV- and melittin-induced flinchings were significantly reduced only by intraplantarly administered CNQX, but not by MK-801. These experimental flinchings suggest that spinal, and partial peripheral mechanisms of NMDA and non-NMDA receptors are involved in the development and maintenance of WBV- and melittin-induced nociceptive responses.

• 대한공간정보학회지
• /
• 제12권4호
• /
• pp.69-74
• /
• 2004

도시화로 인한 사회기반시설의 확충으로 인해 각종 시설물의 관리에 새로운 차원의 관리기술이 요구되고 있다. 90년대부터 GIS는 시설물관리와 계획에 효과적인 기술로 평가되어 정부 및 지자체에서 중장기 계획을 수립하여 시설물 관리시스템을 구축하고 있으며, 관련분야기술을 발전시키기 위한 연구가 지속적으로 이뤄지고 있다. 이런 측면에서 GIS구축 시 수치지도나 영상을 기본도로 사용하는 단점을 개선하기 위해 동영상자료를 이용한 정보시스템구축에 관심이 높아지고 있다. 동영상자료를 이용할 경우 실 세계적인 정보를 사용자에게 제공할 수 있어서 GIS의 사용효과를 더욱 향상시킬 수 있는 장점이 있다. 본 연구에서는 비행선에서 촬영된 비디오동영상과 GPS 위치자료를 이용하여 비디오영상을 수치지도와 연계시키고, 동영상에 나타나는 시설물에 대한 객체추적 및 속성자료 연결을 통해 시설물을 효과적으로 관리할 수 있는 시설물관리시스템을 프로토 타입으로 개발하였다. 제시된 시스템의 기능을 통하여 동영상자료를 이용한 시설물관리시스템의 구축 가능성과 활용성을 제시하였다.

• 한국항해항만학회지
• /
• 제29권6호
• /
• pp.583-588
• /
• 2005

하계 한국 남서연안 해역에는 저온수가 나타나고 안개가 자주 형성되는 것으로 알려져 있다. 본 연구에서는 저온수의 출현시기 및 장소와 이 해역에서 형성되는 안개에 미치는 저온수의 영향에 대해 조사${\cdot}$분석하였다. 그 결과, 저수온역은 초여름 대흑산도 부근해역에서 나타나기 시작하여, 이것은 점차 이동하여 7월 말${\~}$8월 초 진도 남서쪽 해역에 위치하고, 그 후 10월 중순경 이 해역에서 소멸된다. 그리고 이 해역에서는 주로 4${\~}$8월에 안개가 발생하는데, 특히 인근해역에 비해 해면온도가 현저하게 낮은 진도해역에서 안개 발생빈도가 높은 것으로 보아, 이 해역에 나타나는 저온수가 안개의 형성에 상당한 영향을 끼치는 것으로 사료된다.

• 대한의용생체공학회:학술대회논문집
• /
• 대한의용생체공학회 1997년도 춘계학술대회
• /
• pp.141-144
• /
• 1997

Femoral neck anteversion is the angle between the neck and the knee axis projected on a plane perpendicular to the longitudinal axis. Conventional methods that use cross-sectional Computed Tomography(CT) images to estimate femoral anteversion have several problems because of the complex 3D structure of the femur. These are the ambiguity of defining the longitudinal axis, the femoral neck axis and condylar line, and the dependence on patient positioning. Especially the femoral neck axis that is known as a major source of error is hard to determine from a single or multiple 2D transverse images. So we developed a new method for measuring femoral anteversion by 3D modeling method. In this method, femoral head is modeled as a sphere. The center of femoral neck is the mid-point of the 2D reconstructed oblique image in the femoral neck part. Then neck axis is a line connecting foregoing two centers. We model the longitude of femur as a cylinder, and the long axis is defined from the fitted cylinder. The knee axis which is tangent to the back of the femoral condyles is easily determined by table-top method. By the definition of femoral anteversion, the femoral anteversion is easily calculated from this model.

• 구강회복응용과학지
• /
• 제19권1호
• /
• pp.7-15
• /
• 2003

This study used FEM(Finite Element method) based on micro-CT images to see the effects of occlusal force distribution with varying bone density and structure. the mandibular premolar region from human cadaver, thickness of 10mm was imaged using micro-CT. the cross sectional images were taken every $10{\mu}m$. these were reconstructed and the longitudinal image at the mid point of mesiodistal of the speciman was obtained for the specimen for the FEM. The stress disribution produced by a vertical force at 100N and 100N horizontal were analyzed by MSC Nastran FEM Package. according to the result of this study the occlusal force distribution depends on the structure of cancellus bone and for further information on the occlusal force distribution on the tooth and the surrounding structure requires further studies on cancellus bone structure. CEJ of all model show the highest peak and region whice meet teeth and bone show second high peak. Original model and cortical bone add model show different stress distribution. Stress distribution changed according to bone structures and densities.

• 한국한의학연구원논문집
• /
• 제14권3호
• /
• pp.137-148
• /
• 2008

Computerization is recognized as simple supporting tools up to recently but Information is made for the improvement of company's outcome beyond the assistant tools and is emerged as core tools of creating new opportunities for company in point of management strategy. But Information plays minor role in Korean Institute of Oriental Medicine(KIOM) yet. Information has not processed systematically because of lack of understanding and budget in KIOM. The purpose of this research is to make plan for knowledge information which is aimed to make effective supporting and strengthening the ability of KIOM's research, until 2013. Also we tried to find new project s for information and to apply the result to planned information projects. The final goal of this study is to make mid/long-term information plan of KIOM. We applied the general information strategy planning(ISP) method which is progressed as analysis of information technology, analysis of information status, design of future model and extraction of action plan order. First, we examined the information elements for the advanced management from analysis of management environment and analyzed information technology trends. Second, we list up the gaps and problems of KIOM's information status and define the future model to solve this problems. It is showed the road map of time and budget for future model to progress systematically inner-information of purpose. We hope that information of KIOM will be conducted successfully.

• 가정과삶의질연구
• /
• 제28권5호
• /
• pp.113-129
• /
• 2010

This study explored the level and general propensity of the economic distress and the financial management behavior of household financial managers and analyzes the effects of economic distress and the sub dimensions to financial management behaviors. The research results can be summarized as follows. 1. The overall level of economic distress of household financial managers was middle-levels and the financial management behavior were slightly higher than mid-point. 2. Regarding the household variables on the economic distress of household financial managers, education levels and occupations of husbands, monthly income, financial knowledge were the variables that had a significant negative effect on the economic distress. That is, higher education levels of husbands, husbands with management-level/professional-level career, higher monthly income, and higher level of financial knowledge generated lower economic distress. 3. Regarding the household variables and the economic distress on the financial management behavior, monthly income, and financial knowledge were the variables that had a significant positive effect on the financial management behavior. On the contrary, income-asset distress was negative variable. Thus, higher monthly income, higher level of financial knowledge, and lower level of economic distress generated higher financial management behavior. Statistically significant differences were detected in financial management behavior sub dimensions. From this research, it could be concluded that the main variables affecting the level of financial management behaviors are income-asset distresses and financial knowledge.

• ALGAE
• /
• 제31권1호
• /
• pp.33-39
• /
• 2016

Blooms of macroalgae have grown over the planet in recent decades as a possible result of eutrophication of coastal waters. Visually, a bloom forming can be identified by dominant presence of an organism at the expense of others. In mid-January 2014, a forming bloom of red algae was detected on the beach of Garopaba, Santa Catarina State, Brazil. This aroused the interest of tourists and locals as well as the scientific community. Thus, the objective of this study was to characterize and quantify the photosynthetic floating organisms contributing to this phenomenon. In addition, we qualitatively compared algal composition of the bloom to those deposited in the post-beach area and the adjacent rocky shore community. Five sampling points in random patches of floating material were defined. At each point, five replicates were taken with a cube of 32,768 cm³, resulting in a total of 25 samples. Samples were collected in the inner area enclosed by a PVC quadrate of about 900 cm² from the shore and the specimens found in post-beach zone (wrack). Twenty-four taxa of macroalgae were found in the bloom, with Aglaothamnion uruguayense as the dominance one. Ten taxa were found on shore. Only four taxa were found in the post-beach area. The biomass estimated for A. uruguayense in the floating material was 8.35 tons with an estimated area of 52,770 m² . It is possible that this huge biomass value of the bloom is related to the local nutrient intake, and our results reinforce the necessity of coastal integrative management initiatives.

• 대한기계학회논문집A
• /
• 제20권11호
• /
• pp.3516-3524
• /
• 1996

Service conditions for structures at elevated temperatures in nuclear power plant involve transient thermal and mechanical load levels that are severe enough to caeuse inelastic deformations due to creep and plasticity. Therefore, a systematic mehtod of inelastic analysis is needed for the design of structural components in nuclear poser plants subjected to such loading conditions. In the present investigation, the Chabodhe model, one of the unified viscoplastic constitutive equations, was selected for systematic inelastic analysis. The material response was integrated based on GMR ( generallized mid-point rule) time integral scheme and provided to ABAQUS as a material subroutine, UMAT program. By comparing results obtaned from uniaxial analysis using the developed UMAT program with those from Runge-Kutta solutions and experimentaiton, the validity of the adopted Chaboche model and the numerical stability and accuracy of the developed UMAT program were verified. In addition, the developed material subroutine was applied for uniaxial creep and tension analyses for the plate with a hole in the center. The application further demonstrates usefulness of the developed program.

• 한국음향학회지
• /
• 제35권5호
• /
• pp.340-348
• /
• 2016

해수면 생성 배경소음에 대한 코히런스함수를 계산하기 위한 음선 기반 모델은 거리와 방위각에 대한 이중적분의 형태를 띤다. 이를 수치적으로 계산하기 위한 이론적인 고려사항은 본 저자들의 과거의 연구에서 부분적으로 설명되었으나, 해양 환경에서의 수치 해석은 수행된 적이 없다. 본 연구에서는 천해와 심해 환경에서 수치실험을 수행하였고, 이를 통해 코히런스함수는 해저 퇴적층음속에 의존하며, 심해보다는 천해에서 해저 퇴적층음속에 민감하다는 것을 보였다. 비슷한 경향이 수신기 쌍의 자세가 변하는 경우에도 관찰된다. 추가적으로 소음수신각에 대한 소음인텐서티를 표현하기 위한 후처리 기술이 제안되었다. 이 기술은 Harrison의 준해석적 모델과 비교할 때, 출력 자료의 형식에 대한 음선 기반 모델의 단점을 보완할 수 있을 것이다.