• Korean Journal of Adult Nursing
• /
• v.28 no.2
• /
• pp.156-168
• /
• 2016

Purpose: The purpose of this study was to provide basic data by surveying the literature for the past fifteen years (2001-2015). The focus of the search was death anxiety among the elderly. Methods: Sixty-two published works including graduate theses were selected for the Meta-analysis. Results: Study results showed that variables related to familial factors were the most often cited in the review of the manuscripts as relevant to death anxiety among the elderly. Specifically family support was most important. The other variables reported in the literature review were classified into four other groupings: social, physical, psychological, and demographics. The significant variable in the social grouping was religious activities, health promotion in the physical grouping and ego integrity in the psychological group. Conclusion: This study could provide effect sizes of variables based on materials, which are needed to make an intervention program that is related to death anxiety of the elderly. Since this study identified major variables as significant to death anxiety, several distinctions within these variables can be further studied as these relate to death anxiety.

• Asian Pacific Journal of Cancer Prevention
• /
• v.13 no.5
• /
• pp.2003-2007
• /
• 2012

Purpose: E-cadherin is a transmemberane protein which is responsible for adhesion of endothelial cells. The aim of our study was to assess existing evidence of associations between reduced expression of E-cadherin and prognosis of ovarian cancer with a discussion of potential approaches to exploiting any prognostic value for improved clinical management. Methods: We conducted a meta-analysis of 9 studies (n=915 patients) focusing on the correlation of reduced expression of E-cadherin with overall survival. Data were synthesized with random or fixed effect hazard ratios. Results: The studies were categorized by author/year, number of patients, FIGO stage, histology, cutoff value for E-cadherin positivity, and methods of hazard rations (HR) estimation, HR and its 95% confidence interval (CI). Combined hazard ratios suggested that reduced expression of E-cadherin positivity was associated with poor overall survival (OS), HR= 2.10, 95% CI:1.13-3.06. Conclusion: The overall survival of the E-cadherin negative group with ovarian cancer was significant poorer than the E-cadherin positive group. Upregulation of E-cadherin is an attractive therapeutic approach that could exert significant effects on clinical outcome of ovarian cancer.

• Korean Journal of Human Ecology
• /
• v.19 no.5
• /
• pp.835-844
• /
• 2010

This study used meta-analysis to compare analyze data regarding the effects of music therapy on children and adolescent. The study examined 96 ESs using means and standard deviations from 77 Korean degree dissertations conducted between2000 and 2010. Results were as follows: The overall effect size (ES) of the therapy program was found to be 0.14, which, according to Cohen's ES interpretation criteria, is small. The mean ES was influenced by the subjects (children/ adolescents), ES of children(0.50) was bigger than ES of adolescents(-0.23). When results were sorted by the variables of therapy part: social, emotional and behavior development), the ES of social development was the biggest (1.11), followed by behavior development (-1.07) and emotional development (-0.01). However, other variables (total number of procedures, number of treatments per week, the average treatment time, therapist characteristics) made no statistically significant differences to the efficacy of the therapy. Finally, limitations of this study and potential future research are discussed.

• Asian Oncology Nursing
• /
• v.11 no.2
• /
• pp.116-126
• /
• 2011

Purpose: This study was to analyze the characteristics and effect size of intervention studies that used acupressure for the control of chemotherapy-induced nausea and vomiting (CINV). Methods: Nine electronic databases including Korea Education Research and Information, the National Assembly Library, KISS, Korea Med, NDSL, PubMed, EBSCO, Cochrane library, and OVID (to December, 2009) were searched. Thirteen studies of randomized controlled trials (RCTs) or controlled clinical trials (CCTs) were selected. Data were analyzed by SPSS/WIN 18.0. Results: Overall effect size of acupressure was moderate (0.684). Nausea had a moderate effect size (0.770) and nausea and vomiting had a high effect size (0.899). Acupressure using sticker needles had a high effect size (1.368) among finger acupressure, si-acupuncture, and wrist band treatment. Conclusion: This study suggests that acupressure using sticker needles on the spots of nei-guan, chok-samni and hap-kok can reduce the levels of nausea and vomiting in cancer patients receiving chemotherapy. For improving the reliability of the meta-analysis results, further randomized controlled trials with better study methodology are needed.

• Journal of the Korean Society of Clothing and Textiles
• /
• v.37 no.3
• /
• pp.386-398
• /
• 2013

This study analyzes the effect of clothing involvement using meta-analysis. Metal-analysis (the analysis of analyses) is widely used in various academic areas to integrate individual empirical studies and generalize the knowledge of a specific research field. Previous studies regarding clothing involvement published since 1990 were researched from the KISS database using clothing involvement and fashion involvement as a keyword; subsequently, 127 articles were identified. Studies that had insufficient statistics or included clothing involvement as a moderating (or intervening variable) were eliminated; subsequently, 36 articles provided a total of 75 data sets that were used for the final analysis. Dependent variables were grouped into 10 categories to compare the differences between high and low involvement groups. The effect size of clothing involvement was large in non-personal information source; however, it was small in utility, brand royalty and quality. In the 7 categories of relational studies that showed homogeneity, the relation size regarding conformity was smaller than the personal information source.

• Physical Therapy Rehabilitation Science
• /
• v.9 no.1
• /
• pp.55-65
• /
• 2020

Objective: The most important goal of hippotherapy is to improve function, gait, and balance. The purpose of this study was to investigate the effects of hippotherapy on function, gait, and balance of children with cerebral palsy (CP). Design: A systematic review and meta-analysis. Methods: We've searched the PubMed, EMBASE, and Cochrane Library CENTRAL databases for English experimental studies published up until September 2018. To analyze the effects of hippotherapy on the function, gait, and balance of children with cerebral palsy, the systematic review and meta-analysis were performed on Patient/Participants/Population Problem, Intervention, Comparison, Outcome with Timing, Setting Study Design. Papers retrieved from the database were removed from the literature management database. Methodological quality evaluation was evaluated using Cochrane's risk of bias. Data was analyzed using the Revman 5.3 program of the Cochrane library. Results: In this study, we found that the effect size of hippotherapy, denoted as d, was -3.82, and that hippotherapy had the most effect on gait, but no statistical significant difference was observed. We also found no significant difference in function and balance after hippotherapy. It was found from the funnel plot that there was no publication bias as the plot was symmetrically distributed around the dotted line. Conclusions: There are many unclear studies and a lack of randomized controlled trials (RCTs) in this research area. More RCTs on the effects of hippotherapy on children with CP should be conducted in the future.

• Industrial Engineering and Management Systems
• /
• v.13 no.2
• /
• pp.163-171
• /
• 2014

Under amazing increase in markets and certain demand on qualified service in the delivery system, global logistic optimization is becoming a keen interest to provide an essential infrastructure coping with modern competitive prospects. As a key technology for such deployment, we have been engaged in the practical studies on vehicle routing problem (VRP) in terms of Weber model, and developed a hybrid approach of meta-heuristic methods and the graph algorithm of minimum cost flow problem. This paper extends such idea to multi-depot VRP so that we can give a more general framework available for various real world applications including those in green or low carbon logistics. We show the developed procedure can handle various types of problem, i.e., delivery, direct pickup, and drop by pickup problems in a common framework. Numerical experiments have been carried out to validate the effectiveness of the proposed method. Moreover, to enhance usability of the method, Google Maps API is applied to retrieve real distance data and visualize the numerical result on the map.

• Child Health Nursing Research
• /
• v.25 no.1
• /
• pp.56-64
• /
• 2019

Purpose: This study was conducted to obtain data for the development of an effective fall risk assessment tool for pediatric inpatients through a systematic review and meta-analysis of the diagnostic test accuracy of existing scales. Methods: A literature search using Medline, Science Direct, CINAHL, EMBASE, and the Cochrane Library was performed between March 1 and 31, 2018. Of 890 identified papers, 10 were selected for review. Nine were used in the meta-analysis. Stata version 14.0 was used to create forest plots of sensitivity and specificity. A summary receiver operating characteristic curve was used to compare all diagnostic test accuracies. Results: Four studies used the Humpty Dumpty Falls Scale. The most common items included the patient's diagnoses, use of sedative medications, and mobility. The pooled sensitivity and specificity of the nine studies were .79 and .36, respectively. Conclusion: Considering the low specificity of the pediatric fall risk assessment scales currently available, there is a need to subdivide scoring categories and to minimize items that are evaluated using nurses' subjective judgment alone. Fall risk assessment scales should be incorporated into the electronic medical record system and an automated scoring system should be developed.

• Journal of the Korean Society of Food Culture
• /
• v.35 no.6
• /
• pp.553-568
• /
• 2020

This systematic review and meta-analysis aimed to determine whether food intake is effective in preventing diseases related to cognitive impairment. We searched English databases namely MEDLINE, PubMed and ScienceDirect from 2000 to May 2020, and Korean databases namely RISS, KISS, and DBPIA from 1990 to May 2020. We divided the data into 15 groups using the food group classification of the Korean Nutrition Society (KNS). The effect size (Cohen's d) was estimated using a random-effect model, and a 95% confidence interval was calculated for each study. We included 17 cross-sectional studies and 7 cohort studies which involved 45,115 participants. As a result of analyzing the subgroups in the Asian population of both sexes, it was observed that grain intake has a protective effect against cognitive impairment. For females, pulses and fish also have a protective role against cognitive impairment. In the case of seaweed, a negative relationship was found with a moderate protective effect against cognitive impairment (Cohen's d:-0.533, 95% CI: -0.939, -0.126; p=0.010) in Korean studies. Dairy products are associated with an increased risk of cognitive impairment in the American and European population but drinking alcohol is associated with a lower impairment risk. These results provide a basis for formulating the dietary guidelines for preventing dementia for each country.

• Journal of Sasang Constitutional Medicine
• /
• v.34 no.2
• /
• pp.36-47
• /
• 2022

Objectives The purpose of this study was to systematically review previous studies on constitutional herbal medicine treatment for the obesity. Methods A total of 11 databases were searched in English, Chinese, and Korean. Standard methodologies for the systematic review were used to search, analyze and synthesize data for undertaking review and meta-analysis for intervention. The risk of bias was assessed by two independent researchers using the Cochrane risk of bias. Results A total of 2 RCTs were selected and analyzed. The results of the meta-analysis showed a significantly positive effect in the body weight and body mass index for the patient group treated with Taeeumjowi-tang compared to the placebo control group. Conclusions Our results suggested that Taeeumjowi-tang could be considered for improvement of symptoms in obese patients, without serious adverse events. Due to the low quality of the clinical evidence in this study, further studies are needed to evaluate efficacy and safety of constitutional herbal medicines for obesity.