Browse > Article
http://dx.doi.org/10.7730/JSCM.2022.34.2.36

A Systematic Review and Meta-analysis on Constitutional Herbal Medicine Treatment for Obesity  

Lee, Hyeri (Dept. of Sasang Constitutional Medicine, Kyung Hee University Korean Medicine Hospital)
Oh, Hyunjoo (Dept. of Sasang Constitutional Medicine, Kyung Hee University Korean Medicine Hospital)
Lee, Jeongyun (Dept. of Sasang Constitutional Medicine, Div. of Clinical Medicine 4, School of Korean Medicine, Pusan National University)
Lee, Jun-hee (Dept. of Sasang Constitutional Medicine, College of Korean Medicine, Kyung Hee University)
Publication Information
Journal of Sasang Constitutional Medicine / v.34, no.2, 2022 , pp. 36-47 More about this Journal
Abstract
Objectives The purpose of this study was to systematically review previous studies on constitutional herbal medicine treatment for the obesity. Methods A total of 11 databases were searched in English, Chinese, and Korean. Standard methodologies for the systematic review were used to search, analyze and synthesize data for undertaking review and meta-analysis for intervention. The risk of bias was assessed by two independent researchers using the Cochrane risk of bias. Results A total of 2 RCTs were selected and analyzed. The results of the meta-analysis showed a significantly positive effect in the body weight and body mass index for the patient group treated with Taeeumjowi-tang compared to the placebo control group. Conclusions Our results suggested that Taeeumjowi-tang could be considered for improvement of symptoms in obese patients, without serious adverse events. Due to the low quality of the clinical evidence in this study, further studies are needed to evaluate efficacy and safety of constitutional herbal medicines for obesity.
Keywords
Obesity; Sasang Constitutional Medicine; Systematic Review; Taeeumin; Taeeumjowi-tang;
Citations & Related Records
Times Cited By KSCI : 6  (Citation Analysis)
연도 인용수 순위
1 Kim KY. Effects of Taeumin, Soeumin and Soyangin Prescriptions on the Adipocyte Induced by Gold Thioglucose in the Rat. J Sasang Constitut Med. 1996;8(1):295-317. (Korean)
2 Li JE, Song YK, Lim HH. Clinical Trial of Taeeumjowui-Tang(Taiyintiaowei-tang) on Obese Patients - Randomized, Double Blind, Placebo-Controlled Study -. J Oriental Rehab Med. 2010; 20(4):197-213. (Korean)
3 Ministry of Health and Welfare. Korean National Health and Nutrition Examination Survey(KNHANES) 2020. 2022. (Korean)
4 Haslam DW, James WP. Obesity. Lancet. 2005; 366(9492):1197-1209. doi: 10.1016/S0140-6736(05)67483-1.   DOI
5 Kim BY, Kang SM, Kang JH, Kang SY, Kim KK, Kim KB, et al. 2020 Korean Society for the Study of Obesity Guidelines for the Management of Obesity in Korea. J Obes Metab Syndr. 2021;30(2):81-92. (Korean) doi: 10.7570/jomes21022.   DOI
6 Korea Institute of Oriental Medicine. Clinical Practice Guideline of Korean Medicine for Obesity. Seoul:Elsevier Korea L.L.C.. 2016. (Korean)
7 Kim DR, Baik TH. Clinical study on corelation of obesity and Sasang constitution. J Sasang Constitut Med. 1996;8(1):319-335. (Korean)
8 Kim EY, Kim JW. A Clinical study on the Sasang Constitution and Obesity. J Sasang Constitut Med. 2004;16(1):100-111. (Korean)
9 Lee JH, Seo BY, Han SY, Yeon SR, Lee SK, Kwon YD, et al. Study on Relationship between Interleukin-1 Beta Gene Polymorphism and Sasang Constitution in Korean Obese Women. J Oriental Rehab Med. 2005;15(3):127-137.
10 Kim EY, Kim JW. A Clinical study on the Sasang Constitution and Obesity. J Sasang Constitut Med. 2004;16(1):100-111. (Korean)
11 Yang GE, Lee MJ, Lee JS, Yoon DR, Noh HI, Ryu JH. Literature Review of Studies of Obesity U sing Tae-eumin Prescriptions and Herbs - Based on Korean Literature -. J Korean Oriental Med. 2011;32(5):12-24. (Korean)
12 Hur HS, Kang OS. A Review Study of Treatments for Taeeumin Obesity. J Constitut Med. 2019;31(4):28-40. (Korean) doi: 10.7730/JSCM.2019.31.4.28   DOI
13 Kim SY, Park JE, Seo HJ, Lee YJ, Jang BH, Son HJ, et al. NECA's guidance for undertaking systematic reviews and meta-analyses for intervention. 1st ed. Seoul:National Evidence-base Healthcare Collaborating Agency. 2011. (Korean)
14 Borenstein M, Hedges LV, Higgins JPT, Rothstein HR. A basic introduction to fixed-effect and random-effects models for meta-analysis. Res Synth Methods. 2010;1(2):97-111.   DOI
15 Dixon JB, Dixon ME, O'Brien PE. Depression in association with severe obesity: changes with weight loss. Arch Intern Med. 2003;163(17): 2058-2065. doi: 10.1001/archinte.163.17.2058.   DOI
16 Hwang MJ, Shin HD, Song MY. Literature Review of Herbal Medicines on Treatment of Obesity Since 2000 - Mainly about Ephedra Herba. J Korean Med Obes Res. 2007;7(1):39-54. (Korean)
17 Park SJ, Nahmkoong W, Cheon CH, Park JS, Jang BH, Shin YC, et al. Efficacy and Safety of Taeeumjowi-tang in Obese Korean Adults: A Double-Blind, Randomized, and Placebo-Controlled Pilot Trial. Evid Based Complement Alternat Med. 2013;498935. doi: 10.1155/2013/498935   DOI
18 Pak YS, Shin HS, Lee JH, Lee EJ, Koh BH. Approaching obesity through constitutional therapy: a series of 4 obesity cases who were classified as the Taeeum constitutional type. J Sasang Constitut Med. 2011;23(2):263-274. (Korean)   DOI
19 Kim HJ, Kim JY. Clinical Report about the Adverse Reactions of Taeeumin.Soeumin.Soyangin by Taeeumjowi-tang. JPPKM. 2008;22(6): 1600-1605. (Korean)
20 Choi AR, Shin MR, Lee EJ. Clinical Practice Guideline for Taeeumin Disease of Sasang Constitutional Medicine: Esophagus Cold-based Exterior Cold (Wiwansuhan-pyohan) disease. J Sasang Constitut Med. 2015;27(1):42-56. (Korean) doi: 10.7730/JSCM.2015.27.1.042   DOI
21 Moon SH, Koh BH, Song IB. The effects of proliferation and differentiation on adipocyte 3T3-L1 by herbs and herbal prescriptions of Soeumin and Soyangin. Journal of KyungHee Oriental Medicine College. 1998;21(1):453-477. (Korean)
22 Jang SW, Kho YM, Kwak JY, Ahn TW. Anti-obesity Effect of Jeoreongchajeonja-tang in a High-fat Diet-induced Obesity Mouse model. J Sasang Constitut Med. 2018;30(2):8-27. (Korean) doi: 10.7730/JSCM.2018.30.2.8   DOI
23 Song MY, Lee JS, Kim SS, Shin HD. The clinical study about the effect of Chungpaesagan-tang and Taeumjowui-tang on the Taeumin obesity after fasting therapy. J Oriental Rehab Med. 1998; 8(1):34-56. (Korean)
24 Jeon SH, Yu JS, Lee EJ. Clinical Practice Guide line for Taeeumin Disease of Sasang Constitutional Medicine: Liver Heat-based Interior Heat (Gansuyeolliyeol) disease. J Sasang Constitut Med. 2015; 27(1):57-70. (Koraen) doi: 10.7730/JSCM.2015.27.1.057   DOI