• Journal of Acupuncture Research
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• v.33 no.2
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• pp.189-200
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• 2016

Objectives : The purpose of this study is to report the clinical effect of Korean medical treatment on spinal cord infarction. Methods : We treated a patient who was diagnosed with spinal cord infarction. We used acupuncture, bee venom pharmacopuncture, herbal medicine, moxibustion and physical therapy. We evaluated the patient through Manual Muscle Testing (MMT) and International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI) score. Results : MMT grade improved grade from 1 to 5 and ISNCSCI score increased from 2 to 14. Conclusion : According to these results, this report suggests that Korean medical treatment could be effective for spinal cord infarction.

• Journal of Genetic Medicine
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• v.2 no.2
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• pp.83-86
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• 1998

Though Fragile X syndrome is one of the most common inherited causes of mental retardation, it is not much detected yet in Korean population. One of the reason may be that the syndrome is not well known to the special education teachers as well as to the clinicians in this country. Thus, molecular test was undertaken to screen out fragile X syndrome in 122 children of two Korean schools for emotionally severely handicapped children. The subjects were all boys, previously known as having pervasive developmental disorder with or without mental retardation. Southern blot analysis of peripheral blood showed the abnormally enlarged (CGG)n repeat sequence associated with fragile X syndrome in two children. This finding suggests that the DNA testing for fragile X syndrome is warranted for Korean high risk population and that more concern about this syndrome is needed for the professionals who work for mentally handicapped children. The issues involved in genetic counseling for fragile X syndrome are discussed.

• International Journal of Oral Biology
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• v.35 no.4
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• pp.185-190
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• 2010

Methicillin-resistant Staphylococcus aureus (MRSA) is one of the most prevalent pathogens in hospitals. To investigate cross contamination by this bacterium in both dental and medical settings, the pathogens that cause acute pyogenic infection and one of the major microbes responsible for nosocomial infection were isolated from health care providers, nurses and patients. We used VITEK II to measure drug sensitivity, and we further performed biochemical testing, coagulase serotype testing and pulse-field gel electrophoresis (PFGE) for isolated MRSA colonies. The isolation rate of Staphylococcus aureus from nasal swabs was 75.0% from dental health care providers and 18.8% from the medical health care providers. A total of 10 MRSA strains were isolated from 40 health care providers and 2 patients and the prevalent coagulase serotype from patients and health care providers was VII. The antimicrobial drug resistance and partial PFGE types of the isolated MRSA strains showed a similar pattern. These results suggest that MRSA may be one of the principal causes of nosocomial infection in dental and medical hospitals.

• Journal of Preventive Medicine and Public Health
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• v.54 no.1
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• pp.31-36
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• 2021

Objectives: Non-traditional materials are used for mask construction to address personal protective equipment shortages during the coronavirus disease 2019 (COVID-19) pandemic. Reusable masks made from surgical sterilization wrap represent such an innovative approach with social media frequently referring to them as "N95 alternatives." This material was tested for particle filtration efficiency and breathability to clarify what role they might have in infection prevention and control. Methods: A heavyweight, double layer sterilization wrap was tested when new and after 2, 4, 6, and 10 autoclave sterilizing cycles and compared with an approved N95 respirator and a surgical mask via testing procedures using a sodium chloride aerosol for N95 efficiency testing similar to 42 CFR 84.181. Pressure testing to indicate breathability was also conducted. Results: The particle filtration efficiency for the sterilization wrap ranged between 58% to 66%, with similar performance when new and after sterilizing cycles. The N95 respirator and surgical mask performed at 95% and 68% respectively. Pressure drops for the sterilization wrap, N95 and surgical mask were 10.4 mmH2O, 5.9 mmH2O, and 5.1 mmH2O, respectively, well below the National Institute for Occupational Safety and Health limits of 35 mmH2O during initial inhalation and 25 mmH2O during initial exhalation. Conclusions: The sterilization wrap's particle filtration efficiency is much lower than a N95 respirator, but falls within the range of a surgical mask, with acceptable breathability. Performance testing of non-traditional mask materials is crucial to determine potential protection efficacy and for correcting misinterpretation propagated through popular media.

• Journal of the Korean Data and Information Science Society
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• v.28 no.1
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• pp.217-225
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• 2017

This article deals with the problem of multiple hypothesis testing for the shape parameter in the generalized exponential distribution. We propose Bayesian hypothesis testing procedures for multiple hypotheses of the shape parameter with the noninformative prior. The Bayes factor with the noninformative prior is not well defined. The reason is that the most of the noninformative prior can be improper. Therefore we study the default Bayesian multiple hypothesis testing methods using the fractional and intrinsic Bayes factors with the reference priors. Simulation study is performed and an example is given.

• International Journal of Reliability and Applications
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• v.4 no.2
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• pp.57-69
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• 2003

A non-parametric test based on U-statistic for testing exponentiality against the new better than used renewal failure rate (NBURFR) alternatives is introduced and the percentiles of this test statistic are tabulated for sample size 5(1)50. Its properties are also discussed including the Pitman asymptotic efficiency relative to the tests of the new better than used and new better than used failure rate (Ahmed (1994) and Hendi (2000)). The powers of this test are also calculated for some used life distributions. An example from blood cancer patients demonstrates a practical application of our test in the medical sciences is presented. Finally the problem when right-censored data is available is handled.

• Clinical and Experimental Pediatrics
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• v.63 no.6
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• pp.195-202
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• 2020

Developments in next-generation sequencing (NGS) techogies have assisted in clarifying the diagnosis and treatment of developmental delay/intellectual disability (DD/ID) via molecular genetic testing. Advances in DNA sequencing technology have not only allowed the evolution of targeted panels but also, and more currently enabled genome-wide analyses to progress from research era to clinical practice. Broad acceptance of accuracy-guided targeted gene panel, whole-exome sequencing (WES), and whole-genome sequencing (WGS) for DD/ID need prospective analyses of the increasing cost-effectiveness versus conventional genetic testing. Choosing the appropriate sequencing method requires individual planning. Data are required to guide best-practice recommendations for genomic testing, regarding various clinical phenotypes in an etiologic approach. Targeted panel testing may be recommended as a firsttier testing approach for children with DD/ID. Family-based trio testing by WES/WGS can be used as a second test for DD/ID in undiagnosed children who previously tested negative on a targeted panel. The role of NGS in molecular diagnostics, treatment, prediction of prognosis will continue to increase further in the coming years. Given the rapid pace of changes in the past 10 years, all medical providers should be aware of the changes in the transformative genetics field.

• Journal of KIISE
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• v.43 no.9
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• pp.953-962
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• 2016

Model-based testing is a technique for performing the test by using a model that represents the behavior of the system as a system specification. Industrial domains such as automotive, military/aerospace, medical, railway and nuclear power generation require model-based testing and code coverage-based testing to improve the quality of software. Despite the fact that both model-based testing and code coverage-based testing are required, difficulty in achieving a high coverage using model-based testing caused by the abstraction level difference between the test model and the source code, results in the need for performing model-based testing separately. In this study, to overcome the limitations of the existing model-based testing, we proposed the state machine transformation method to effectively improve the code coverage using the protocol state machine, one of the typical modeling methods is used as the test model in model-based testing, as the test model. In addition, we performed a case study of both systems and analyzed the effectiveness of the proposed method.

• The Journal of Korean Physical Therapy
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• v.26 no.5
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• pp.344-350
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• 2014

Purpose: The purpose of this study was to translate and culturally adapt the International Classification of Functioning, Disability and Health (ICF) into the Korean language. Methods: The process of translation and adaptation of the ICF used here followed the translation guidelines of WHO. Implementation of this procedure comprised of four steps; forward translation, expert panel back-translation, pre-testing and cognitive interviewing, and final adaptation. The translators included health professionals with knowledge of ICF and non-health professionals blinded to the ICF. Clinical academics with significant experience in the use of disability survey, medical doctors, special educators, related policy makers, clinicians, architecture professionals, and international experts in ICF were invited to integrate all versions of the ICF for testing; 151 clinicians volunteered from 19 medical institutes across the country. Four different core-sets and a questionnaire were used for testing its practical usability and adaptation. Results: All translations were reviewed and a consensus was reached on any discrepancy from the earlier versions. Over 90% of the newly translated version of K-ICF was found to be different from the 2004 K-ICF version in the ICF language. Understanding of K-ICF language was responded difficult and very difficult by 50% of participants, whereas its practical use was responded 'useful' by more than 50% of subjects. Conclusion: It can be suggested that the new version of K-ICF should be widely used for final adaptation in the field of areas. Future studies will be required for implementation of K-ICF.

• Journal of Biomedical Engineering Research
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• v.40 no.1
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• pp.20-31
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• 2019

Medical device performance management is an activity that allows a device to be safely used and maintained even after it is put on the market. The purpose of this study is to provide procedures and criteria for selection of medical device items that should manage the safety and performance among medical devices in hospital. Investigate the performance management status of medical devices in hospitals and identify the performance management status by domestic and advanced regulatory agencies. Provides selection procedures and test methods for medical devices subject to performance management in hospitals based on medical device risk management and reliability. In addition, a case study on drug infusion pumps was conducted.