• The Journal of the Convergence on Culture Technology
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• v.9 no.6
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• pp.229-235
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• 2023

This study was to examine the role for children's prosocial behavior in terms of maternal parenting behavior, smart-media addiction and ADHD-related behaviors. The study sample was 537 children who had participated in the tenth wave of the Panel Study on Korean Children. The data were analyzed for descriptive statistics, correlation, and serial multiple mediation analysis. The results of this study are as follows. First, it was found that the direct effect of maternal parenting behavior on children's prosocial behavior was not significant. Second, in the relationship between the maternal parenting behavior and the children's prosocial behavior, the mediating effects of smart-media addiction and ADHD-related behaviors were significant, respectively. Third, in the effect of maternal parenting behavior on children's prosocial behavior, it was found that smart-media addiction and ADHD-related behaviors mediate it in series. These results provide to a better understanding of the process between maternal parenting behavior to children's prosocial behavior and especially emphasize the importance of smart-media addiction and ADHD-related behaviors.

• The Journal of the Convergence on Culture Technology
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• v.9 no.5
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• pp.919-926
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• 2023

Aim(s): This study aims to explore the relationship between multicultural awareness, multicultural acceptance and sensitivity of nursing students in the midst of rapid changes in multiculturalism, and to explore the direction for improving multicultural awareness as health care workers in the future. A survey was conducted among 135 nursing students from two universities in one region, and 108 students, excluding random responses and dropouts, were the final subjects for analysis. For data analysis, frequency analysis, correlation analysis, reliability analysis and mediation effects were tested using SPSS and process Macros. The results confirmed a statistically significant relationship between multicultural awareness and multicultural acceptance (r=.572, p<.001). The relationship between mutual cultural sensitivity, multicultural acceptance (r=.650, p<.001) and multicultural awareness (r=.456, p<.001) also showed a significant positive correlation. In addition, the effect of mutual cultural sensitivity was confirmed in the relationship between multicultural awareness and multicultural acceptance. As a result, in the relationship between multicultural awareness and multicultural acceptability, intercultural sensitivity ranged from 0.188 to 0.554, and the 95% confidence interval did not include 0; thus, indirect effect was statistically significant. Considering these results, it was confirmed that it is important to increase multicultural awareness and intercultural sensitivity in order to increase multicultural acceptance.

• Knowledge Management Research
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• v.24 no.4
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• pp.87-102
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• 2023

Awe is recognized as an emotion linked to enhancing openness to new experiences and broadening one's cognitive perspective through the acquisition of new knowledge. This research aimed to investigate awe's impact on consumer behavior in advertising, using a 2 (emotion: awe/control) × 2 (product type: innovative/non-innovative) experimental design with 118 undergraduate students in Seoul, Korea. Findings revealed that awe-inducing advertising significantly increases product preference and positive technology readiness, particularly for innovative products compared to non-innovative ones or when awe is not elicited. The analysis of moderated mediation showed that positive technology readiness plays a mediating role in the relationship between awe induction and product preference. Notably, in the case of innovative products, awe-inducing advertising heightens positive technology readiness, subsequently increasing consumer preference for these products. These results reinforce existing literature on awe's positive effects, demonstrating its role in augmenting consumers' favorable attitudes toward innovative products. The study offers valuable insights for marketing strategies of companies promoting innovative products or services, highlighting the effectiveness of awe-inducing emotional appeals in shaping consumer attitudes towards innovation.

• The Journal of the Convergence on Culture Technology
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• v.10 no.2
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• pp.565-574
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• 2024

ChatGPT is causing significant reverberations across all sectors of our society, and this holds true for the field of education as well. However, scholarly and societal discussions regarding ChatGPT in academic settings have primarily focused on issues such as plagiarism, with relatively limited research on the positive effects of utilizing generative AI. Additionally, amidst the educational crisis of the post-COVID era, there is a growing recognition of the need to enhance academic engagement. In light of these concerns, we investigated how academic engagement varies based on students' levels of ChatGPT literacy and examined whether students' academic confidence and perceived academic competence serve as mediators between ChatGPT literacy and academic engagement. An analysis using SPSS was conducted on the data collected from 406 college students. The results showed that ChatGPT literacy had a positive effect on academic engagement, and academic confidence mediated the relationship between ChatGPT literacy and academic engagement. Also, when the mediating effect of perceived academic competence was significant only when it was serially mediated. Based on these findings, we discussed the theoretical contributions of identifying the theoretical mechanism between ChatGPT literacy and academic engagement. In addition, practical implications regarding the importance of ChatGPT literacy education were described.

• Journal of Venture Innovation
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• v.7 no.1
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• pp.111-130
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• 2024

The purpose of this study is to investigate whether self-leadership affects organizational commitment through job satisfaction of employees working in domestic mold-related companies. Questionnaires were collected online for a period of three months from employees working in domestic mold-related companies., A total of 209 questionnaires were used for the final analysis, and the questionnaires were composed of self-leadership, organizational commitment, and job satisfaction. In order to improve the early turnover problem and job competence of employees working in domestic mold-related companies, the effect of self-leadership on organizational commitment and job satisfaction and the effect of self-leadership on organizational commitment through job satisfaction were verified. As a result of the verification, it was proved that self-leadership had a significant effect on organizational commitment and job satisfaction, and job satisfaction had a complete mediating effect between self-leadership and organizational commitment.,This proved that the stronger the self-leadership and the higher the job satisfaction, the greater the impact on organizational commitment, thus laying the foundation for self-leadership education for mold-related workers in companies and associations.

• Journal of Venture Innovation
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• v.7 no.1
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• pp.41-57
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• 2024

This study analyzed the relationship between the level of the venture environment, the benefits of the venture business verification system, internal capabilities, and management performance through the actual data of domestic venture companies collected in the Venture Business Precision Survey. As a result of the empirical analysis, the level of venture infrastructure did not affect the company's capabilities, but it was found that the venture company confirmation system had a positive effect. In the case of corporate competency, it was found that it had a positive effect on technological performance, but had no effect on sales performance. However, the research results confirmed that internal competency mediates the relationship between the venture environment level and the benefits of the venture business confirmation system and business performance. This study has the implications of confirming a series of processes leading to competency and performance in the environment using data from actual venture companies, and confirming the importance of corporate competency. In addition, since we confirmed the effect of the environmental factors of the venture environment level and the venture business confirmation system on the internal performance, if the process is introduced in the later reorganized venture business confirmation system, we will examine the factors that can enhance the performance of venture businesses. A more precise check is expected.

• Korean Journal of Biological Psychiatry
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• v.12 no.1
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• pp.42-61
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• 2005

Objectives:The ginsenoside Rg1 and Rb1, the major components of ginseng saponin, have neurotrophic and neuroprotective effects including promotion of neuronal survival and proliferation, facilitation of learning and memory, and protection from ischemic injury and apoptosis. In this study, to investigate the molecular basis of the effects of ginsenoside on neuron, we analyzed gene expression profiling of SH-SY5Y human neuroblastoma cells treated with ginsenoside Rg1 or Rb1. Methods:SH-SY5Y cells were cultured and treated in triplicate with ginsenoside Rg1 or Rb1($80{\mu}M$, $40{\mu}M$, $20{\mu}M$). The proliferation rates of SH-SY5Y cells were determined by MTT assay and microscopic examination. We used a high density cDNA microarray chip that contained 8K human genes to analyze the gene expression profiles in SH-SY5Y cells. We analyzed using the Significance Analysis of Microarray(SAM) method for identifying genes on a microarray with statistically significant changes in expression. Results:Treatment of SH-SY5Y cells with $80{\mu}M$ ginsenoside Rg1 or Rb1 for 36h showed maximal proliferation compared with other concentrations or control. The results of the microarray experiment yielded 96 genes were upregulated(${\geq}$3 fold) in Rg1 treated cells and 40 genes were up-regulated(${\geq}$2 fold) in Rb1 treated cells. Treatment with ginsenoside Rg1 for 36h induced the expression of some genes associated with protein biosynthesis, regulation of transcription or translation, cell proliferation and growth, neurogenesis and differentiation, regulation of cell cycle, energy transport and others. Genes associated with neurogenesis and neuronal differentiation such as SCG10 and MLP increased in ginsenoside Rg1 treated cells, but such changes did not occur in Rb1-group. Conclusion:Our data provide novel insights into the gene mechanisms involved in possible role for ginsenoside Rg1 or Rb1 in mediating neuronal proliferation or cell viability, which can elicit distinct patterns of gene expression in neuronal cell line. Ginsenoside Rg1 have more broad and strong effects than ginsenoside Rb1 in gene expression and related cellular physiology. In addition, we suggest that SCG10 gene, which is known to be expressed in neuronal differentiation during development and neuronal regeneration during adulthood, may have a role in enhancement of activity dependent synaptic plasticity or cytoskeletal regulation following treatment of ginsenoside Rg1. Further, ginsenoside Rg1 may have a possible role in regeneration of injured neuron, promotion of memory, and prevention from aging or neuronal degeneration.

• Tuberculosis and Respiratory Diseases
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• v.62 no.4
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• pp.299-307
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• 2007

Background: High mobility group box 1 (HMGB1) is a novel, late mediator of inflammation. This study compared the pro-inflammatory effects of LPS and HMGB1. The transcriptional factors that play an important role in mediating the HMGB1-induced stimulation of IL-8 were also evaluated. Methods: RAW264.7 cells were stimulated with either LPS (100 ng/ml) or HMGB1 (500 ng/ml). The $TNF-{\alpha}$, MIP-2 and $IL-1{\beta}$ levels in the supernatant were evaluated by ELISA at 0, 2, 4, 8, 12 and 24h after stimulation. An acute lung injury was induced by an injection of LPS (5 mg/kg) or HMGB1 (2.5 mg/kg) into the peritoneum of the Balb/c mice. The lung cytokines and MPO activity were measured at 4h (for LPS) or 24h (for HMGB1) after the injection. The transcriptional factor binding sites for NF-IL6, $NF-{\kappa}B$ and AP-1 in the IL-8 promoter region were artificially mutated. Each mutant was ligated with pIL-6luc and transfected into the RAW264.7 cells. One hour after stimulation with HMGB1 (500 ng/ml), the cell lysate was analyzed for the luciferase activity. Results: The expression of MIP-2, which peaked at 8h with LPS stimulation, increased sequentially until 24h after HMGB1 stimulation. An intraperitoneal injection of HMGB1, which induced a minimal increased in $IL-1{\beta}$ expression, provoked the accumulation of neutrophils the lung. A mutation of AP-1 as well as $NF-{\kappa}B$ in the IL-8 promoter region resulted in a lower luciferase activity after HMGB1 stimulation. Conclusion: The proinflammatory effects of HMGB1, particularly on IL-8, are mediated by both $NF-{\kappa}B$ and AP-1.

• Asia-Pacific Journal of Business Venturing and Entrepreneurship
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• v.14 no.4
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• pp.113-132
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• 2019

The degree of females' participation in corporate activity has been recently increased over the world and females' participation in economic activity may be new dynamic fuel for the Korean economy that falls into the vicious cycle of low growth. Start-up, therefore, has increasingly taken attention as an opportunity for females whose careers were interrupted to re-enter the labor market. The need for studies that examine factors influencing the decision of start-up is also increased along with the increase of the ratio of females' start-up. This study aims to verify effects of the women's characteristics(women discrimination, women's role conflict) and the human networks of females whose careers were interrupted, with the intention for entrepreneurial intention, which are mediated by personal attitudes and subjective norm suggested by Ajzen's Theory of Reasoned Action, based on an empirical research. The findings show that the human networks of females have an effect on attitudes toward start-up activity and subjective norm and the woman discrimination influence the personal attitudes. In contrast, the women's role conflict have no effect on both personal attitude toward start-up activity and subjective norm. This can be supposed as an outcome resulted from the subjects' low level of conflict caused by their sex roles, on their age distribution. The relation between subjective norm and entrepreneurial Intention seemed to be moderated by their perceived strong entrepreneurial supporting policy. Their attitudes toward start-up activity were found to have a mediating effect on the relation between the women discrimination, human networks and entrepreneurial Intention, while the subjective norm only mediated the relation between human networks and entrepreneurial Intention. Based on such results, this study attempts to suggest theoretical suggestions and the direction of various entrepreneurial supporting policy for the increase and the growth of start-up of females whose careers were interrupted, in Korea.

• 한국노년학
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• v.39 no.4
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• pp.723-739
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• 2019

This study is to verify the mediated effects of attitudes toward old people and dementia in the influence of elderly couples in the aging society amid the rapidly changing family structure and functions due to the combination of individualization, marital status and divorce rate. In order to carry out such research purposes, data were collected from students of elementary, middle and high schools in Gwangju, through self-subscribed questionnaire. For statistical analysis, the SPSS 20.0 and AMOS 18.0 programs were used and frequency, percentages, technical statistics, correlation, factor analysis, structural model validation, and the Sobel-Test were performed. The results of this study are as follows. First, family intimacy, elderly awareness, and elderly care were the highest among elementary school students, followed by middle school and high school students (P.<.001). Also, in religion, the family intimacy of teenagers with religion was higher than those without religion (p.001). Second, family intimacy directly affected elderly people's attitudes toward dementia and elderly care, old people's attitudes toward dementia and attitudes toward dementia directly affected elderly care. Third, family intimacy (parent-child) was found to be 7.8% for older adults, 20.2% for family intimacy and attitudes toward dementia, and 34.1% for elderly care (p.<.001). Fourth, it has been verified that the absolute value of attitudes toward dementia and elderly people's awareness of elderly people and attitudes between family intimacy and elderly care has been higher than 1.96 and thus acts as a mediating role. These findings are intended to contribute to the welfare of senior citizens' education to improve the quality of life for senior citizens through the resolution of conflicts between generations, as well as the resolution of positive stimulus, by developing various programs such as family friendship, elderly awareness, culture with parents, and various experiences to improve attitudes toward dementia in early adolescence.