• Journal of Life Science
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• v.21 no.10
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• pp.1355-1363
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• 2011

Many clinical trials have demonstrated the beneficial effects of garlic (Allium sativum) on general cardiovascular health. Aged garlic extract (AGE) is known to display diverse biological activities such as in antioxidant, anti-inflammatory and anticancer activities. However, few studies have been directed on the effect of AGE on cardiovascular function. In this study, we aimed to investigate the effect of AGE and its components on platelet activation, a key contributor in thrombotic diseases. In freshly isolated rat platelets, AGE and its components have shown inhibitory activities on thrombin-induced platelet aggregation. These in vitro results were further confirmed in an in vivo platelet aggregation measurement where tail vein injection of garlic oil and S-Allylmercapto-cysteine (SAMC) significantly reduced thrombin and ADP-induced platelet aggregation. Potential active components for antiplatelet effects of AGE were identified to be SAMC and diallyl sulphide through agonist-induced platelet aggregation assay. These results indicate that aged garlic extract can be a novel dietary supplement for the prevention of cardiovascular risks and the improvement of blood circulation.

• Journal of the Korea Safety Management & Science
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• v.6 no.1
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• pp.157-172
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• 2004

The results of this study has been split into two components, On set of results addressed the strategy of developing a Agility for maintenance consumer. The other set of results addressed the strategy of illuminating the successful measurement and concepts formed during the maintenance problem solving process, especially in the context of the Logistics Information system by aggregation information space. This paper presented a classifiable elements of Agility & Measurement of logistics capability in the Korea market. These concepts are positioned in a framework to give a better understanding what the consequences are of the changing business environment. The developments towards more globalization which leads to centralization and mass individualization that has a tendency to go more in the decentralized solutions, seems to be in contradiction. we will focus a proposal of Logistics information system and demand management decisions that should be a prime concern of any profit maximizing firm, unready strategy of investment. and we will prove the facts that it could be a guiding company which has a ability of cooperation with entities through the founding of supply chain, On the conclusion, we will show the variation which influences for capacity entities and alternative proposal to define a element which influnce for a cause and effect basically.[5]

• The Journal of Korean Medicine
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• v.18 no.1
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• pp.299-315
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• 1997

The present experiments were designed to investigate the effects of Samsaengyeum. water extracts on the Cardiovascular System in the Experimental Animals. Thus, the changes of blood pressure and heart rate were measured after oral administration. Measurement of Mortality rate was observed for measuring the effect of Samsaengyeum water extract Samsaengyeum water extract against pulmonary thromboembolism induced by collagen the mixture(0.1me/10g, 2mg/kg B.W) plus serotonin(5mg/kg B.W) in mouse. The effect of Samsaengyeiim water extract was examined by observing the change of collagen-induced platelet aggregation, coagulation activity, ex vivo and in vitro fibrinolytic activity of euglobulin fraction in rats. The results were summarized as followings. 1. Samsaengyeum dropped the blood pressure in spontaneous hypertensive rat. 2. The drug increased the auricular blood flow in rabbit. 3. The drug relaxed the artery contraction by pretreated norepinephrine in rat. 4. The drug inhibited the death rate of mouse which was led to thromboembolism by serotonin and collagen. 5. The drug inhibited the platelet aggregation in rat. 6. The drug prolonged the prothrombin time and activated partial thromboplastin time on the test of plasma coagulation factor activity in rat, but was not valuable. 7. The drug reduced the fibrinogen lyses time and increased the lyses area of rat. 8. Samsaengyeum reduced fibrinogen lyses time of rat in vitro assay. According to the above mentioned results, Samsaengyeum increased the blood flow and dropped the blood pressure by the dilation of blood vessel. And the drug inhibited the platelet aggregation.

• Rapid Communication in Photoscience
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• v.3 no.4
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• pp.81-84
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• 2014

To examine the microenvironmental effect of DNA on the photosensitized reaction, the electron-donor-connecting porphyrin, meso-(9-phenanthryl)-tris(N-methyl-p-pyridinio) porphyrin (Phen-TMPyP), was synthesized. Phen-TMPyP can bind to oligonucleotides with two binding modes, depending on the DNA concentration. The fluorescence lifetime measurement of Phen-TMPyP shows a shorter component than that of the reference porphyrin without the phenanthryl moiety. However, the observed value is much longer than those of previously reported similar types of electron-donor-connecting porphyrins, suggesting that electron-transfer quenching by the phenanthryl moiety is not sufficient. The fluorescence quantum yield of Phen-TMPyP ($5{\mu}M$) decreased with an increase in DNA concentration of up to $5{\mu}M$ base pair (bp), possibly due to self-quenching through an aggregation along the DNA strand, increased with an increase in DNA concentration of more than $5{\mu}M$ bp and reached a plateau. The fluorescence quantum yield of Phen-TMPyP with a sufficient concentration of DNA was larger than that of the reference porphyrin. The singlet oxygen ($^1O_2$) generating activity of Phen-TMPyP was confirmed by the near-infrared emission spectrum measurement. The quantum yield of $^1O_2$ generation was decreased by a relatively small concentration of DNA, possibly due to the aggregation of Phen-TMPyP, and recovered with a sufficient concentration of DNA. The recovered quantum yield was rather smaller than that without DNA, indicating the quenching of $^1O_2$ by DNA. These results show that a DNA strand can stabilize the photoexcited state of a photosensitizer and, in a certain case, suppresses the $^1O_2$ generation.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.10 no.1
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• pp.79-95
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• 2016

In order to improve the Quality-of-Service (QoS) of latency sensitive applications in next-generation cellular networks, multi-path is adopted to transmit packet stream in real-time to achieve high-quality video transmission in heterogeneous wireless networks. However, multi-path also introduces two important challenges: out-of-order issue and reordering delay. In this paper, we propose a new architecture based on Software Defined Network (SDN) for flow aggregation and flow splitting, and then design a Multiple Access Radio Scheduling (MARS) scheme based on relative Round-Trip Time (RTT) measurement. The QoS metrics including end-to-end delay, throughput and the packet out-of-order problem at the receiver have been investigated using the extensive simulation experiments. The performance results show that this SDN architecture coupled with the proposed MARS scheme can reduce the end-to-end delay and the reordering delay time caused by packet out-of-order as well as achieve a better throughput than the existing SMOS and Round-Robin algorithms.

• Bulletin of the Korean Chemical Society
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• v.10 no.5
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• pp.437-442
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• 1989

The cmc's of sodium dodecyl sulfate (SDS)/Triton X-100 surfactant mixtures were determined by surface tension measurement at various surfactant compositions. The cmc values were lower than those predicted from ideal mixture. The regular solution theory was applied to calculate the interaction parameter, micellar composition, and the activity coefficients of surfactants in the mixed micelle. The interaction parameter (${\beta}$) was - 2.1. The nonideality arised largely from decreased activity of SDS in the mixed micelle. The mean aggregation numbers (${\bar{n}}$) and micropolarity of hydrocarbon region of the mixed micelles were determined by luminescence probe techniques. The total aggregation number (${\bar{n}}_{SDS}+{\bar{n}}_{TX}$) in mixed micelles showed little dependency on the composition of the micelle. The apparent dielectric constant of the hydrocarbon region of the micelle vs micellar composition plot showed positive deviation from linearity. Emission and emission quenching of excited tris(2,2'-bipyridine)ruthenium(Ⅱ) cation, $(Ru(bpy)_3^{2+})$, by methylviologen ($MV^{2+}$) were also investigated in the mixed micellar solutions. The quenching rate was lowest when the mole fraction of SDS in the surfactant mixtures (${\alpha}_{SDS}$) is about 0.25 and highest at ${\alpha}_{SDS}$ = 0.85. This was explained in terms of combined effects of binding of the cations with the micelle and mobility of the bound cations on the surface of the micelles.

• Journal of the Korean Institute of Electrical and Electronic Material Engineers
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• v.18 no.1
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• pp.81-88
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• 2005

The Langmuir monolayers of polyamic acid salts with three kinds of alkyl chains have been investigated by means of conventional $\pi$-A isotherms and second harmonic generation measurements proposed in this paper. The surface molecular density dependence of second harmonic intensity clearly shows the region of aggregation while corresponding $\pi$-A isotherm doesn't show any changes in the surface morphology at the same region. The surface morphology analysis based on the second harmonic measurement was consistent with the Brewster angle microscope measurement results.

• Journal of Physiology & Pathology in Korean Medicine
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• v.18 no.5
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• pp.1516-1519
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• 2004

I studied on the influence of Gi-Gong gymnastics in the live blood condition of women's shoulder measurement. The results are as follows: In the Erythrocyte Aggregation(4 women), the three women were not observed at all and one woman was observed a little, In the Rouleau(3 women), three women were not observed at all. In the Target Cells(3 women), the two women were not observed at all and one woman was observed a little. In the Ovalocytes (3 women), the one woman was not observed at all and two women were observed a little. And in the Poikilocytes (1 woman), one woman was observed a little, In the Cholesterol Crystals(3 women), the two women were observed a little and one woman was observed as things stand, In the Atherosclerotic Plaque(2 women), the two women were not observed at all. In the Chylous(3 women), the two women were observed a little and one woman was observed as things stand.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.16 no.11
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• pp.2437-2445
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• 2012

This paper presents the efficient measurement method of radio resource by analyzing various medium occupied elements. The medium occupied time consists of 802.11 frames, wireless interference, and protocol waiting time from a wireless node on a current channel. And it is used to performance metric. Existing research is only measured partial occupied elements, and is lack of validation of measurement unit and scalability on various IEEE 802.11 radio. This paper presents the measurement method of classified occupied elements. To achieve this, we modified 802.11n based OpenHAL device driver to collect the register information of wireless chipset, and to analyze receiving frames in an virtual monitor mode. We conclude accurate medium occupied time measurement system from various validation methods.

• Nuclear Engineering and Technology
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• v.55 no.9
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• pp.3140-3149
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• 2023

In theory, the sharp dose falloff at the distal end of a proton beam allows for high conformal dose to the target. However, conformity has not been fully achieved in practice, primarily due to beam range uncertainty, which is approximately 4% and varies slightly across institutions. To address this issue, we developed a new range verification system prototype: a multi-slit prompt-gamma camera (MSPGC). This system features high prompt-gamma detection sensitivity, an advanced range estimation algorithm, and a precise camera positioning system. We evaluated the range measurement precision of the prototype for single spot beams with varying energies, proton quantities, and positions, as well as for spot-scanning proton beams in a simulated SSPT treatment using a phantom. Our results demonstrated high accuracy (<0.4 mm) in range measurement for the tested beam energies and positions. Measurement precision increased significantly with the number of protons, achieving 1% precision with 5 × 10⁸ protons. For spot-scanning proton beams, the prototype ensured more than 5 × 10⁸ protons per spot with a 7 mm or larger spot aggregation, achieving 1% range measurement precision. Based on these findings, we anticipate that the clinical application of the new prototype will reduce range uncertainty (currently approximately 4%) to 1% or less.