• Asian Pacific Journal of Cancer Prevention
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• v.17 no.4
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• pp.1973-1978
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• 2016

Background: Breast cancer is a heterogeneous disease that represents a major public health problem. The immunohistochemical determination of breast cancer subtypes with regard to estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor (HER2) status can contribute to improved selection of therapy and patientcare. The purpose of this study was to determine the prevalence of the molecular breast cancer subtypes and to assess their associations with classical clinicopathologic parameters for better therapeutic decisions in women with breast cancer in the Ivory Coast. Materials and Methods: Formalin-fixed and paraffin-embedded blocks of patients diagnosed with primary breast carcinoma were subjected to immunohistochemical assay for the assessment of ER/RP and HER2 expression. The one-way analysis of variance evaluated the difference between breast cancer subtypes and mean age of patients. The Chi-square Test was used to compare standard clinicopathologic prognostic parameters with tumor subtypes. Results. Among 302 patients, 57% were premenopausal and 43% were postmenopausal. The invasive ductal carcinoma not otherwise specified (IDC NOS) (82.8%) was the most frequent histological type, and the tumor grade 2 (56%) was predominant followed by grade 3 (20.9%). The proportion of positivity of ER, PR, and HER2 was 56%, 49%, and 15.6%, respectively. Half of patients of this study (51.6%) had luminal A breast tumor type followed by TN (32.1%). Other subtypes were luminal B (10.1% ) and non-luminal HER2+ (6.3%). Conclusions. The findings of the present study are in line with the literature and should assist in management of breast cancer in our country.

• Korean Journal of Applied Biomechanics
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• v.22 no.1
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• pp.83-94
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• 2012

The purpose of this study was to analyse the effect of posture correction & stabilization according to horse rider's(n=10) skill levels of novice(0wk), mid-skill(12wk) & skill(24wk) in walk & trot. First, Mean posture of 3 times experiments; Anterior & posterior leaning posture of trunk showed rather unstable according to progress of the stages of TD1, TO, TD2 phase, and also shoulder & elbow angle, which effects to the distance from bit to rein, showed unstable riding posture. There was close relationship between shoulder and elbow Angle in walk and hip, knee & ankle angle in trot. Second, Posture correction & stabilization according to riding skill levels; Anterior & posterior leaning posture of trunk did not show significant difference statistically but showed approaching tendency to trunk's vertical line and showed significant difference(p<.05) according to improvement of skill levels in walk & trot horse riding. Hip angle showed significant difference according to progress of the stages of TD1, TO, TD2 phase(p<.05) and showed tendency maintaining the larger thigh flexion according to improvement of skill levels in walk & trot. Knee angle showed more stable posture by maintaining the larger flexion between thigh and shank according to improvement of skill levels in walk & trot(p<.05). Ankle angle also showed tendency maintaining the larger plantar flexion of foot according to improvement of skill levels in walk & trot. When considering the above, regular horse riding program could be useful in posture correction & stabilization according to improvement of skill levels of novice(0wk), mid-skill(12wk) & skill(24wk) in walk & trot.

• Proceedings of the Korean Society of Soil and Groundwater Environment Conference
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• 2006.04a
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• pp.432-435
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• 2006

To evaluate geology and extent of leachate migration around the landfills, electrical resistivity survey were conducted in area of uncontrolled landfills in Cheonan and Wonju. The Cheonan landfill is located above the paddy fields and the resistivity survey lines were crossed to confirm possible pollution of the paddy fields by leakage of the landfill leachate. In Wonju, the landfill and the downgradient paddy fields are divided by a concrete barrier wall. At the bottom of the landfill, there is a leachate settlement system but has not been in operation. And a total of 4 survey line installed (1 parallel and 3 perpendicular to mean groundwater flow direction). According to the resistivity survey results, the landfill leachate in Cheonan appeared to be restricted only within the interior of the landfill, not to migrate into the subsurface of the paddy fields. These results are well consistent with electrical conductivity values of groundwaters obtained from a periodic analysis of water qualities. In Wonju, however, it was inferred that the leachate emanating from the landfill migrated beneath the abandoned leachate settlement system and it would reach the downgradient paddy field.

• The Journal of the Korea Contents Association
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• v.10 no.1
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• pp.399-406
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• 2010

This paper is to analyze which factors affect preference, satisfaction, and revisiting on McDonald's brand personality and to suggest distinguished guidelines for drawing core customers. The questionary distributed 150 who is college students in dokyo, Japan, then used for data analysis 128. The results come up with; First, 4 variables which are 'up-to-date', 'spirited', 'darling', and 'young' showed up importantly in brand personality. These mean young generation would like to enjoy playing on-line game and contents with computer on the table during wait their order. Second, 3 factors (sincerity, intelligence/specialization, and wholesome) in brand personality had highly significant in preference and satisfaction. When they feel strongly specialization and trust in product, it should be showed highly with preference and satisfaction. Third, 2 factors (sincerity, and intelligence/specialization) had strongly significant in revisiting. As marketer reinforce darling and specialized image about McDonald, Therefore, they should make customer to purchase again. Finally, if customer prefered and satisfied with product in the restaurant, it could be connected rebuying.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.9 no.5
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• pp.567-577
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• 1998

When continuous and discontinuous microstrip is analyzed with FDTD(Finite Difference Time Domain) method, we used Berenger's 3D-PML as absorbing boundary condition, and IST(Inner Source Technique) was used for source excitation instead of front excitation that is existing method. In the case using IST, we have observed that analyzed characteristic is not affected by the reduced computational domain of the side and top face in which evanescent field and radiation field is exist. Also, if we control the position of the inner source, we could effectively reject the influence of the reflective wave by mean of imperfective boundary condition. In this paper, by using IST, we have calculated dispersive characteristic and characteristic impedance of the microstrip. And we have calculated magnitude and phase of the scattering coefficient, and obtained equivalent circuit of the open microstrip end.

• Journal of the Korean association of regional geographers
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• v.8 no.1
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• pp.98-109
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• 2002

The long term land-cover changes and the pattern of morphological changes in foredune ridges and unvegetated dunes were investigated for about 30 years through analysing aerial photographs in Shinduri coastal dunefield, Korea. As a result, forested dune area increased while unvegetated dune area decreased continuously since 1967. Foredune ridges retreated landward about 80m away from the former coast-line in the middle part while they advanced seaward after construction of dike in the northern part during last 3 decades. Unvegetated dunes in the middle part of the dunefield were eroded at seaward side and moved landward away. These facts mean not only coastal dune area has been affected by man-made effects such as afforestation and coastal developments but also shinduri coastal dune area has been stabilized by plants and has been negative sediment budget.

• Journal of Korean Institute of Industrial Engineers
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• v.39 no.3
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• pp.172-182
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• 2013

In this study we consider a flow line CONWIP system in which two types of product are produced. The processing times of each product type at each station follow an independent exponential distribution and the demands for the finished products of each type arrive according to a Poisson process. The demands that are not satisfied instantaneously are either backordered or lost according to the number of unsatisfied demands that exist at their arrival instants. For this system we develop an approximation method to obtain the performance measures such as steady state probabilities of the number of parts of each product type at each station, mean waiting times of backordered demands and the proportion of backordered demands. For the analysis of the proposed CONWIP system, we model the CONWIP system as a two class closed queueing network with a synchronization station and analyze the closed queueing network using a product-form approximation method for multiple classes developed by Baynat and Dallery. In the approximation method, each subsystem is analyzed using a matrix geometric method. Comparisons with simulation show that the approximation method provides fairly good results for all performance measures.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2007.06a
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• pp.45-45
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• 2007

Capacitors among the embedded passive components are most widely studied because they are the major components in terms of size and number and hard to embed compared with resistors and inductors due to the more complicated structure. To fabricate a capacitor-embedded PCB for in-line process, it is essential to adopt a low temperature process (<$200^{\circ}C$). However, high dielectric materials such as ferroelectrics show a low permittivity and a high dielectric loss when they are processed at low temperatures. To solve these contradicting problems, we studied BMN materials as a candidate for dielectric capacitors. processed at PCB-compatible temperatures. The morphologies of BMN thin films were investigated by AFM and SEM equipment. The electric properties (C-F, I-V) of Pt/BMN/Cu/polymer were evaluated using an impedance analysis (HP 4194A) and semiconductor parameter analyzer (HP4156A). $Bi_2Mg_{2/3}Nb_{4/3}O_7$(BMN) thin films deposited on copper clad laminate substrates by sputtering system as a function of Ar/$O_2$ flow rate at room temperature showed smooth surface morphologies having root mean square roughness of approximately 5.0 nm. 200-nm-thick films deposited at RT exhibit a dielectric constant of 40, a capacitance density of approximately $150\;nF/cm^2$, and breakdown voltage above 6 V. The crystallinity of the BMN thin films was studied by TEM and XRD. BMN thin film capacitors are expected to be promising candidates as embedded capacitors for printed circuit board (PCB).

• Journal of Genetic Medicine
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• v.11 no.2
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• pp.69-73
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• 2014

Purpose: Spinocerebellar ataxia (SCA) is a genetically heterogeneous disease for which more than 30 subtypes have been identified. However, 5 subtypes, SCA1, SCA2, SCA3, SCA6, and SCA7, account for more than 60% of cases. In this study, we report the distribution of these 5 subtypes in Korean patients. Materials and Methods: Six hundred and thirty-eight unrelated patients with a presumptive diagnosis of SCA were included in this study. Trinucleotide (CAG) repeat number (TNR) repeat number was determined using fluorescently labeled primers and fragment analysis. Results: A total of 128 unrelated patients (20.1% of all individuals tested) tested positive for SCA subtypes, including SCA1 (5 patients, 3.9% of those testing positive), SCA2 (38 patients, 29.7%), SCA3 (30 patients, 23.4%), SCA6 (39 patients, 30.5%), and SCA7 (16 patients, 12.5%). The mean copy number of pathogenic TNR alleles was $45{\pm}8.5$ for SCA1, $42{\pm}3.1$ for SCA2, $72{\pm}5.4$ for SCA3, $23{\pm}1.5$ for SCA6, and $50{\pm}11.4$ for SCA7. TNR copy number was inversely correlated with onset age in SCA2, SCA6, and SCA7. Conclusion: SCA2, SCA3, and SCA6 are common SCA subtypes in Korean patients and could be screened as a first-line test. Expanded pathogenic allele size was associated with early onset age.

• Journal of Korean Neurosurgical Society
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• v.38 no.3
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• pp.202-205
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• 2005

Objective : The purpose of this study is to measure the dimensions of foramen ovale and to localize the zygomatic point using computed tomography[CT] in Korean adults with idiopathic trigeminal neuralgia. Methods : Facial axial CT scans using the orbitomeatal plane were performed in 67patients [39males and 28females; mean age 58.8years] with idiopathic classic trigeminal neuralgia. We measured the size of the foramen ovale and localized the zygomatic point which was a skin marker over the ipsilateral zygoma that approximates the lateral projection of a straight line joining the centers of the two foramen ovale. Results : The axial dimensions of the foramen ovale on the orbitomeatal plane were of average length : $8.18{\pm}0.82mm$ [range $6.9{\sim}11.5mm$]. width : $4.06{\pm}0.86mm$ [$2.5{\sim}5.7mm$]. The average distance between the external acoustic meatus and the zygomatic point was $21.64{\pm}1.99mm$ [$16.3{\sim}25.0mm$] and the average distance of anterior margin of condylar process of mandible to zygomatic point was $4.29{\pm}1.19mm$ [$1.0{\sim}7.0mm$]. Conclusion : The anatomical understandings including the size of the foramen ovale and localization of the zygomatic point could be helpful in determining a plan of percutaneous approaches to foramen ovale.