• Title/Summary/Keyword: Mass spectroscopy

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Tumor-like Presentation of Tubercular Brain Abscess: Case Report

  • Karki, Dan B.;Gurung, Ghanashyam;Sharma, Mohan R.;Shrestha, Ram K.;Sayami, Gita;Sedain, Gopal;Shrestha, Amina;Ghimire, Ram K.
    • Investigative Magnetic Resonance Imaging
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    • v.19 no.4
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    • pp.231-236
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    • 2015
  • A 17-year-old girl presented with complaints of headache and decreasing vision of one month's duration, without any history of fever, weight loss, or any evidence of an immuno-compromised state. Her neurological examination was normal, except for papilledema. Laboratory investigations were within normal limits, except for a slightly increased Erythrocyte Sedimentation Rate (ESR). Non-contrast computerized tomography of her head revealed complex mass in left frontal lobe with a concentric, slightly hyperdense, thickened wall, and moderate perilesional edema with mass effect. Differential diagnoses considered in this case were pilocytic astrocytoma, metastasis and abscess. Magnetic resonance imaging (MRI) obtained in 3.0 Tesla (3.0T) scanner revealed a lobulated outline cystic mass in the left frontal lobe with two concentric layers of T2 hypointense wall, with T2 hyperintensity between the concentric ring. Moderate perilesional edema and mass effect were seen. Post gadolinium study showed a markedly enhancing irregular wall with some enhancing nodular solid component. No restricted diffusion was seen in this mass in diffusion weighted imaging (DWI). Magnetic resonance spectroscopy (MRS) showed increased lactate and lipid peaks in the central part of this mass, although some areas at the wall and perilesional T2 hyperintensity showed an increased choline peak without significant decrease in N-acetylaspartate (NAA) level. Arterial spin labelling (ASL) and dynamic susceptibility contrast (DSC) enhanced perfusion study showed decrease in relative cerebral blood volume at this region. These features in MRI were suggestive of brain abscess. The patient underwent craniotomy with excision of a grayish nodular lesion. Abundant acid fast bacilli (AFB) in acid fast staining, and epithelioid cell granulomas, caseation necrosis and Langhans giant cells in histopathology, were conclusive of tubercular abscess. Tubercular brain abscess is a rare manifestation that simulates malignancy and cause diagnostic dilemma. MRI along with MRS and magnetic resonance perfusion studies, are powerful tools to differentiate lesions in such equivocal cases.

DUST PRODUCTION BY EVOLVED STARS IN THE MAGELLANIC CLOUDS

  • KEMPER, F.
    • Publications of The Korean Astronomical Society
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    • v.30 no.2
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    • pp.283-287
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    • 2015
  • Within the context of the hugely successful SAGE-LMC and SAGE-SMC surveys, Spitzer photometry observations of the Large and Small Magellanic Clouds have revealed millions of infrared point sources in each galaxy. The brightest infrared sources are generally dust producing and mass-losing evolved stars, and several tens of thousands of such stars have been classified. After photometrically classifying these objects, the dust production by several kinds of evolved stars - such as Asymptotic Giant Branch stars and Red Supergiants - can be determined. SAGE-Spec is the spectroscopic follow-up to the SAGE-LMC survey, and it has obtained Spitzer-IRS $5-40{\mu}m$ spectroscopy of about 200 sources in the LMC. Combined with archival data from other programs, observations at a total of ~1000 pointings have been obtained in the LMC, while ~250 IRS pointings were observed in the SMC. Of these, a few hundred pointings represent dust producing and mass-losing evolved stars, covering a range in colors, luminosities, and thus mass-loss rates. Red Supergiants and O-rich and C-rich AGB stars - the main dust producers - are well represented in the spectroscopic sample. This paper will summarize what we know about the mineralogy of dust producing evolved stars, and discuss their relative importance in the total dust budget.

Flavonol glycosides from the flowers of Carthamus tinctorius and their anti-diabetic activity (잇꽃(Carthamus tinctorius)으로부터 Flavonol glycoside 화합물들의 분리 및 항당뇨 효과)

  • Bo-Ram Choi;Hyoung-Geun Kim;Yoon Hee Nam;Dahye Yoon;Woo Cheol Shin;Jin-Kyu Jang;Yunji Lee;Tong Ho Kang;Nam-In Baek;Dae Young Lee
    • Journal of Applied Biological Chemistry
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    • v.66
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    • pp.477-483
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    • 2023
  • The flowers of Carthamus tinctorius (Safflower) were extracted with 80% aqueous methanol (CTex) and the concentrates were partitioned into EtOAc (CTE), n-BuOH (CTB), and H2O (CTW) fractions. Repeated silica gel (SiO2) and octadecyl silica gel column chromatographies for the EtOAc and n-BuOH fractions led to isolation of four flavonol glycosides. Nuclear magnetic resornance, infrarad spectroscopy, and mass spectroscopy revealed the chemical structure of the isolated compounds, astragalin (1), isoquercetin (2), nicotiflorin (3), and rutin (4). Quantitative analysis of four isolated compounds in CTex was performed by HPLC. CTex was found to contain 1 at 0.107, 2 at 0.367, 3 at 6.752, and 4 at 0.991 mg/g, respectively. Through this study, an experiment was conducted to evaluate the protective effect on pancreatic islets of the extract, solvent fractions, and all isolated compounds using a zebrafish larvae damaged by alloxan. Pancreatic islet size treated with EtOAc (CTE), n-BuOH (CTB), and H2O (CTW) fractions and compounds 1-4 significantly increased compared to the alloxan-induced group. These results indicate that C. tinctorius flowers and its isolated compounds are used as potential anti-diabetic agents.

Effect of boron doping on the chemical and physical properties of hydrogenated amorphous silicon carbide thin films prepared by PECVD (플라즈마 화학증착법으로 제조된 수소화된 비정질 탄화실리콘 박막의 물성에 대한 붕소의 도핑효과)

  • 김현철;이재신
    • Journal of the Korean Vacuum Society
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    • v.10 no.1
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    • pp.104-111
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    • 2001
  • B-doped hydrogenated amorphous silicon carbide (a-SiC:H) thin films were prepared by plasma-enhanced chemical-vapor deposition in a gas mixture of $SiH_4, CH_4,\;and\; B_2H_6$. Physical and chemical properties of a-SiC:H films grown with varing the ratio of $B_2H_6/(SiH_4+CH_4)$ were characterized with various analysis methods including scanning electron microscopy (SEM), X-ray diffractometry (XRD), Raman spectroscopy, Fourier-transform infrared (FTIR) spectroscopy, secondary ion mass spectroscopy (SIMS), UV absorption CH_4spectroscopy and electrical conductivity measurements. With the B-doping concentration, the doping efficiency and the micro-crystallinity were decreased and the film became amorphous when $B_2H_6/(SiH_4{plus}CH_4)$ was over $5{\times}10^{-3}$. The addition of $B_2H_6$ gas during deposition decreased the H content in the film by lowering the quantity of Si-C-H bonds. Consequently, the optical band gap and the activation energy of a-SiC:H films were decreased with increasing the B-doping level.

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CONSTRAINING SUPERNOVA PROGENITORS: AN INTEGRAL FIELD SPECTROSCOPIC SURVEY OF THE EXPLOSION SITES

  • KUNCARAYAKTI, H.;ALDERING, G.;ANDERSON, J.P.;ARIMOTO, N.;DOI, M.;GALBANY, L.;HAMUY, M.;HASHIBA, Y.;KRUEHLER, T.;MAEDA, K.;MOROKUMA, T.;USUDA, T.
    • Publications of The Korean Astronomical Society
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    • v.30 no.2
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    • pp.139-143
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    • 2015
  • We describe a survey of nearby core-collapse supernova (SN) explosion sites using integral field spectroscopy (IFS) techniques, which is an extension of the work described in Kuncarayakti et al. (2013). The project aims to constrain SN progenitor properties based on the study of the immediate environment of the SN. The stellar populations present at the SN explosion sites are studied by means of integral field spectroscopy, which enables the acquisition of both spatial and spectral information of the object simultaneously. The spectrum of the SN parent stellar population gives an estimate of its age and metallicity. With this information, the initial mass and metallicity of the once coeval SN progenitor star are derived. While the survey is mostly done in optical, the additional utilization of near-infrared integral field spectroscopy assisted with adaptive optics (AO) enables us to examine the explosion sites in high spatial detail, down to a few parsecs. This work is being carried out using multiple 2-8 m class telescopes equipped with integral field spectrographs in Chile and Hawaii.

Classification of Red Wines by Near Infrared Transflectance Spectroscopy

  • W.Guggenbichler;Huck, C.W.;M.Popp;G.K.Bonn
    • Proceedings of the Korean Society of Near Infrared Spectroscopy Conference
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    • 2001.06a
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    • pp.1516-1516
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    • 2001
  • During the recent years, wine analysis has played an increasing role due the health benefits of phenolic ingredients in red wine [1]. On the other hand there is the need to be able to distinguish between different wine varieties. Consumers want to know if a wine is an adulterated one or if it is based on the pure grape. Producers need to certificate their wines in order to ensure compliance with legal regulations. Up to now, the attempts to investigate the origin of wines were based on high-performance liquid chromatography (HPLC), gas chromatography (GC) and pyrolysis mass spectrometry (PMS) [l,2,3]. These methods need sample pretreatment, long analysis times and therefore lack of high sample throughput. In contradiction to these techniques using near infrared spectroscopy (NIRS), no sample pretreatment is necessary and the analysis time for one sample is only about 10 seconds. Hence, a near infrared spectroscopic method is presented that allows a fast classification of wine varieties in bottled red wines. For this, the spectra of 50 bottles of Cabernet Sauvignon, Lagrein and Sangiovese (Chianti) were recorded without any sample pretreatment over a wavelength range from 1000 to 2500 nm with a resolution of 12 cm$\^$-1/. 10 scans were used for an average spectrum. In order to yield best reproducibility, wines were thermostated at 23$^{\circ}C$ and a optical layer thickness of 3 mm was used. All recorded spectra were partitioned into a calibration and validation set (70% and 30%). Finally, a 3d scatter plot of the different investigated varieties allowed to distinguish between Cabernet Sauvignon, Lagrein and Sangiovese (Chianti). Considering the short analysis times this NRS-method will be an interesting tool for the quality control of wine verification and also for experienced sommeliers.

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Spectroscopy of Local Starburst Galaxies (가까운 폭발적 항성생성은하의 분광 관측)

  • Lee, Cheolhui;Shim, Hyunjin
    • Journal of the Korean earth science society
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    • v.38 no.3
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    • pp.209-221
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    • 2017
  • We investigate the star formation rate, stellar mass, and gas-phase metallicity of local starburst galaxies with different star formation time scales based on their optical spectra. The observation is made using the longslit spectrograph attached to the 4K CCD on the Bohyunsan Optical Astronomy Observatory 1.8m telescope, targeting 21 Wolf-Rayet galaxies as young starbursts and 13 UV excess galaxies as slightly older starbursts. A Baldwin-Phillips-Terlevich diagram analysis shows that 50% of the observed targets are pure star-forming galaxies while only 15% are classified as Active Galactic Nuclei. Fraction of galaxies that reside in composite region is higher in UV excess galaxies than in Wolf-Rayet galaxies, suggesting that the AGN development requires extra time after the onset of the star formation. Most of the observed starburst galaxies have stellar masses of $10^{9-11}M_{\odot}$ and stellar formation rates of $0.01-100M_{\odot}yr^{-1}$, and their star formation rates are consistent with that of the SDSS star forming main sequence galaxies of similar stellar mass. There is no significant difference between Wolf-Rayet galaxies and UV excess galaxies in terms of the stellar mass and star formation rate. We also see a mass-metallicity relation for local starbursts with slightly lower metallicity for a given stellar mass, which implies the existence of a strong feedback activity due to the star formation in these galaxies.

A study on Ultrashallow PN junction formation by boron implantation in Silicon (실리콘에 Boron 이온 주입에 의한 Ultrashallow PN접합 형성에 관한 연구)

  • 김동수;정원채
    • Proceedings of the IEEK Conference
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    • 2000.06b
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    • pp.56-59
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    • 2000
  • In this paper, we have made a comparison between secondary ion mass spectroscopy(SIMS) data by the 5kcV-15keV boron implantation and computer simulation results. In order to make electrical activation of implanted carriers, thermal annealing are carried out by RTP method for 30s at 1000$^{\circ}C$ Two dimensional doping concentration distribution from different mask dimensions under inert gas annealing, dry-, and wet-oxidation condition were calculated and simulated with microtec simulator.

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ON THE INTERFACE BETWEEN TITANIUM METAL AND BONE TISSUE -Ti-ion leakage from bone and implant interface(1)- (티타늄금속과 골조직의 계면에 관한 연구 -골과 임플란트 계면에서의 Ti-ion의 거동에 대하여(1)-)

  • Cho, Sung-Am;Jo, Kyung-Hun;Sur, Jo-Ryung
    • The Journal of Korean Academy of Prosthodontics
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    • v.33 no.2
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    • pp.354-357
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    • 1995
  • The secondary ion of titanium from commercially pur titanium implant which installed at Rabbit tibia. Was analyzed by Secondary lon Mass Spectroscopy. And we detected about 3476 ppm ion from $10-50{\mu}m$ distance from interface.

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Characterization of a thermostable fructosyltransferase from Leuconostoc mesenteroides TL1

  • Lee, Gwang-Ok;Gang, Hui-Gyeong;Kim, Do-Man
    • 한국생물공학회:학술대회논문집
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    • 2003.04a
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    • pp.527-529
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    • 2003
  • A fructosyltransferase from Leuconostoc mesenteroides TL1 was purified. The molecular mass of the enzyme was estimated to be 38 kDa based on the activity staining. The pH and temperature optima of the enzyme were 6.3 and $40^{\circ}C$, respectivly. Structural analysis of the polymer prepared from sucrose by the enzyme was determined by NMR Spectroscopy: It shows the heterogeneous linkages of levan-like fructan and dextran-like glucan.

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