• Journal of the korean academy of Pediatric Dentistry
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• v.36 no.4
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• pp.575-579
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• 2009

Behcet's disease(BD) is a multisystem vasculitis that almost any organ in the body may be involved. Its diagnosis bases on clinical criteria in the absence of any specific laboratory test to confirm it. The clinical criteria proposed for the diagnosis for BD include recurrent oral and genital ulceration, skin lesion, ocular changes, and positive response to pathergy test. Besides these essential features, BD may manifest itself on the gastrointestinal tract, central nervous system, and other systemic involvements. Among these clinical features, recurrent oral ulcers are present in most BD patients, often as the initial symptom, preceding other manifestations by many years. Therefore, dentists are in the important position for the early detection and diagnosis of BD. In this case report, we are presenting a case of 6 year-old girl, who came to the pediatric dentistry department for evaluation and treatment of pain and dysphagia caused by severe recurrent oral ulcers. Through taking detailed dental and medical history and clinical examination, we reported the possibility of BD to the medical team and prescribed topical lidocaine to relief pain during swallowing. The medical team, which involved pediatrics, ophthalmology, dermatology, and gastroenterology, finally confirmed BD through various examinations. Detection of the possibility of BD in the dental field helped early diagnosis and proper management by the medical team.

• Journal of Radiation Protection and Research
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• v.38 no.3
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• pp.143-148
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• 2013

Operational nuclear facilities such as nuclear power plants and particle accelerators show various neutron spectra according to the type of facilities and specific position. Necessities of neutron dose management and neutron monitoring for radiation protection of radiation workers in such a kind of facilities have continuously increased in recent years. Bonner sphere spectrometers are widely used for measurement of neutron spectra. Data on response function of neutron detector, default neutron spectra and count rates of Bonner sphere spectrometer are required to obtain unfolded neutron spectra in specific workplaces. In this study, we carried out measurement of neutron spectra produced in MC50 cyclotron using Bonner sphere spectrometer with LiI scintillation detector. Additionally, we estimated quantitative data on neutron flux, mean neutron energy and ambient dose equivalent rate according to the incident proton energies and positions in MC50 cyclotron.

• Journal of Aquaculture
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• v.20 no.4
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• pp.226-231
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• 2007

We investigated survival and osmolarity, oxygen consumption, amonia extetion and filtration rates associated with physiological responses of the tunicate Halocynthia roretzi salinity changes. Acclimation times for osmolatity in different salinities took $20{\sim}26$ hours in 60% SW (19.8 psu) and $20{\sim}25$ hours in 80% SW (26.4 psu), while their times took $7{\sim}8$ hours in 110% SW (36.3 psu). Accordingly, acclimation times for high salinities were faster than those for low salinities. Survival (%) was more than 80% at salinity over 26.4 psu, and 6 $days-LS_{50}$ was 25.4 psu. physiological responses such as oxygen consumption, amonia excretion and filtration rates of H. roretzi showed more clear reactions in the longer exposure period (four days after exposure) than that in the beginning of the exposure. To sum up the results, the tunicate might be stressed from the beginning of the exposure in low salinity.

• Culinary science and hospitality research
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• v.19 no.2
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• pp.176-189
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• 2013

This study has been conducted on 213 students in 4-year universities located in the regions of Daejeon and Chungnam in order to investigate a method to develop a smart device based culinary education application and the results and development method were as follows. First, the most often used smart device was a smart phone, which is used for over 5 hours a day and mainly used for SNS. Second, they utilized a smart device for language and major study during their spare time, wanted educational contents most and thought them useful for learning. Third, most of the students were positively aware of the necessity and learning effects of culinary education applications, and the response rate to utilize the application once a week was highest. Also, they hoped various recipes and simple cuisine and craftsman cooking. Therefore, the functions of SNS mostly often used by students should be added to promote interaction between teachers and students. And more contents should be made for students to use easily in moving or in their spare time. Furthermore, various videos of teaching and theoretical information should be included. And the applications focused on recipes and simple and craftsman cooking should be developed and uploaded on a school homepage and on popular portal sites so that students can easily utilize them.

• Sleep Medicine and Psychophysiology
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• v.2 no.1
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• pp.55-64
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• 1995

During sleep, relatively major respiratory physiological changes occur in healthy subjects. The contributions and interactions of voluntary and metabolic breathing control systems during waking and sleep are quite different Alterations of ventilatory control occur in chemosensitivity, response to mechanical loads, and stability of ventilation. The activities of intercostal muscles and muscles involved in regulating upper airway size are decreased during sleep. These respiratory physiological changes during sleep compromise the nocturnal ventilatory function, and sleep is an important physiological cause of the nocturnal alveolar hypoventilation. There are several causes of chronic alveolar hypoventilation including cardiopulmonary, neuromuscular diseases. Obstructive sleep apnea syndrome (OSAS) is an important cause of nocturnal hypoventilation and hypoxia. Coexistent cardiopulmonary or neuromuscular disease in patients with OSAS contributes to the development of diurnal alveolar hypoventilation, diurnal hypoxia and hypercapnia. The existing data indicates that nocturnal recurrent hypoxia and fragmentation of sleep in patients with OSAS contributes to the development of systemic hypertension and cardiac bradytachyarrhythmia, and diurnal pulmonary hypertension and cor pulmonale in patients with OSAS is usually present in patients with coexisting cardiac or pulmonary disease. Recent studies reported that untreated patients with OSAS had high long-term mortality rates, cardiovascular complications of OSAS had a major effect on mortality, and effective management of OSAS significantly decreased mortality.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.20
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• pp.8969-8974
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• 2014

Background: The aim of this study was to determine the predictors of health promoting lifestyle behaviour among medical students attending seven of the medical schools in Turkey. Materials and Methods: This crosssectional descriptive study was performed during the second semester of the first and last (sixth) years of study from March to May 2011. A questionnaire with two sections was specifically designed. The first section contained questions on demographic characteristics; the second consisted of the Health Promoting Lifestyle Profile II (HPLP) Scale. From a total of 2,309 medical students, 2,118 (response rate 91.7%) completed the questionnaire. Data were analyzed using descriptive statistics, t, Anova, Tukey test and binary logistic regression analysis. The research was approved by the Ethics Committee of Erciyes University. Results: The mean age was $20.7{\pm}2.9$ years and it was found that 55.1% were men, 62.3% were in the first year. The overall prevalence of smoking was 19.1%, and for drinking alcohol was 19.4%. HPLP point averages of the first year students were $129.2{\pm}17.7$, and for last year $125.5{\pm}19.0$. The overall mean score for the HPLP II was $2.5{\pm}0.4$. They scored highest on the spiritual growth subscale ($2.9{\pm}0.5$), interpersonal relations ($2.8{\pm}0.5$), health responsibility subscale ($2.3{\pm}0.5$), nutrition subscale ($2.3{\pm}0.5$), stress management subscale ($2.3{\pm}0.4$), and the lowest subscale physical activity ($2.0{\pm}0.5$). It is established that student's grade, educational level of parents, economic status of family, marital status, smoking and general health perception of the students resulted in a significant difference in HPLP Scale total score average and the mean score of majority of subscales. There was no statistically significant difference between the total HPLP when evaluated for gender, chronic disease, alcohol drinking status and BMI. Conclusions: Based on these results, particularly in the curriculum of medical students in order to increase positive health behaviours including physical activity, health promotion issues, and giving more space to aim at behaviour change in these matters is recommended.

• Journal of the Korean Applied Science and Technology
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• v.37 no.5
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• pp.1125-1137
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• 2020

This study investigated whether swimming exercise suppresses(: inhibites) the inflammatory response in adipose tissue in obese mice induced by a high fat diet after ovariectomy in female mice. Experimental group and control group were divided into sham-opereated group (Sham), ovariectomized group (OVX), and ovariectomized group with swimming exercise (OVX/Ex). All female mice fed high fat diet (45% fat) for 8 weeks. Compared with the Sham, the OVX increased the weight of visceral adipose tissue including parametrial, retroperitoneal, and mesenteric adipose tissue. Compared to the OVX, the OVX/Ex demonstrated reductions the weight of visceral adipose tissue. Compared to the Sham, the OVX decreased the mRNA expression of IκBα and increased the mRNA expression of inflammatory cytokines (L-6, MCP-1, TNF-α and leptin) in adipose tissue. But the OVX/Ex appeared to increase the mRNA expression of IκBα and decrease the mRNA expression of inflammatory cytokines in adipose tissue, compared with the OVX. This findings suggested that swimming exercise is useful for preventing adipose tissue inflammation, which will be effective in the prevention and treatment of obesity in obese mice induced obesity by a high fat diet after ovariectomy.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.18 no.10
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• pp.745-755
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• 2017

University campuses try to satisfy students' demands. Therefore, the physical environment of university campuses keeps changing. Due to the increasing the number of students and shortage of school building facilities, it is necessary to improve the facilities and create new space in the campus, in order to solve this problem and improve the universities. At the moment, the learning method of university students is evolving toward discussion sessions involving fellow students and presentations utilizing multimedia facilities. In response to these changes, a new type of independent space has appeared, which is called the Group Study Room. In this study, we analyze the spatial characteristics of the Group Study Room. Also, through an IPA(Importance Performance Analysis), this study tries to examine the relationship between the spatial characteristics and users' satisfaction. This analysis is expected to reveal the importance of the spatial characteristics of the group study rooms from the users' point of view. This research can be used for facility planning in universities in the future. The primary aim of this study is to analyze the physical environment of the Group Study Rooms of K university. The secondary aim of this study is to manifest the characteristics of these new learning spaces and to check the space elements of the group study rooms for the sake of efficient planning and management.

• Asian-Australasian Journal of Animal Sciences
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• v.33 no.1
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• pp.53-60
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• 2020

Objective: The current study was carried out to examine the response of different levels of fat and protein in calf starter on nutrient utilisation, nitrogen metabolism, weight gain, blood parameters, and immunity level in pre-ruminant calves. Methods: Twenty four calves (5 days old) were divided into six groups in a 2×3 factorial design, with two levels of fat (10% and 14%) and three levels of protein (18%, 21%, and 24%). The calves were kept in individual pens for 120 days and fed with whole milk (1/10th of body weight) and calf starter ad-libitum. Daily dry matter intake was recorded; whereas body weight was taken on fortnightly basis to calculate average daily gain. During the growth trial blood samples were collected at 30 days interval to estimate blood glucose, albumin, total protein, total leucocyte count, total immunoglobulins and immunoglobulin G levels. A metabolic trial of seven days was carried out to find out the digestibility of different nutrients. Results: The dry matter intake was reduced (p<0.05) with higher fat and protein levels whereas feed conversion efficiency was improved (p<0.05) with higher protein level. Different levels of fat and protein in calf ration did not affect average daily gain in calves. The dry matter, organic matter, and crude protein digestibility were significantly (p<0.01) higher with increased level of protein. The nitrogen retention was also significantly higher (p<0.05) at 24% protein level, similarly the total immunoglobulin was significantly (p<0.05) high in higher protein fed groups, showed better immunity. Conclusion: The present finding suggested that 10% fat and 18% protein level of calf starter could be used in Sahiwal calves for optimum performance in terms of weight gain and immunity.

• The Korea Journal of Herbology
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• v.30 no.1
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• pp.67-75
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• 2015

Objectives : The aim of this study is to examine the neuroprotective effect of wheat bran extract (WBE) against ${\beta}$-amyloid ($A{\beta}$)-induced apoptotic cell death in SH-SY5Y human neuroblastoma cells and memory impairment in triple transgenic animal model's of Alzheimer's disease (3xTg AD mice). Methods : In SH-SY5Y cells, MTT assay and TUNEL staining were conducted to evaluate the protective effect of WBE against $A{\beta}_{25-35}$-induced neurotoxicity and apoptosis. Alterations in mitochondrial transmembrane potential (MMP), expression of proapoptotic Bax and antiapoptotic Bcl-2 proteins, cleavage of PARP, and brain-derived neurotrophic factor (BDNF) levels were analyzed to elucidate the neuroprotective mechanism of WBE. To further investigate the memory enhancing effect of WBE, Morris water maze test was performed in 3xTg AD mice. Results : In SH-SY5Y cells, WBE protected against $A{\beta}_{25-35}$-caused cytotoxicity and apoptosis as shown by the restoration of cell viability in MTT assay and inhibition of DNA fragmentation in TUNEL staining. $A{\beta}_{25-35}$-induced apoptotic signals such as dissipation of MMP, decreased Bcl-2/Bax ratio, and cleavage of PARP were suppressed by WBE. Moreover, WBE up-regulated the protein levels of BDNF, which seemed to be mediated by activation of cAMP response element-binding protein (CREB). In 3xTg AD mice, oral administration of WBE attenuated learning and memory deficit as verified by reduced mean escape latency in water maze test. Conclusions : WBE protects neuronal cells from $A{\beta}_{25-35}$-induced apoptotic cell death and restores learning and memory impairments in 3xTg AD mice. These findings suggest that WBE exhibit neuroprotective potential for the management of AD.