• Tuberculosis and Respiratory Diseases
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• v.47 no.4
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• pp.525-532
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• 1999

The parathyroid hormone related protein (PTHrP) is the most common causative peptide of humoral hypercalcemia of malignancy. In contrast, the serum level of parathyroid hormone (PTH) is low to undetectable in the majority of patients with malignancy associated hypercalcemia. Few cases exist in which the production and secretion of PTH by malignant nonparathyroid tumors have been authenticated. To our knowledge, there is very rare case in which a nonparathyroid tumor expressed simultaneously both the PTH and PTHrP. We report a case of squamous cell carcinoma of the lung with hypercalcemia which presented with simultaneous elevation of serum PTH and PTHrP. Severe hypercalcemia (serum calcium, 7.5 mEq/L) was found in a 65-year-old man who had a squamous cell carcinoma of the lung without any bony metastasis and detectable parathyroid abnormalities on isotope scintigraphy. The serum level of intact parathyroid hormone (PTH) con centration was markedly elevated as measured in two site radioimmunoreactive PTH assays (intact PTH 150 pg/mL ; normal 9~55). The serum level of a PTHrP was also increased as measured in C-terminal region specific radioimmunoassay (PTHrP 99.1 pmol/L; normal 13.8~55.3). There are no evidences of coincidental primary hyperparathyroidism in parathyroid MIBI scan and other imaging studies including neck ultrasonography and computed tomography. These results suggest that simultaneous elevation of serum PTH and PTHrP in this patient can be caused by production of both PTHrP and PTH in other nonparathyroid lesions such as squamous cell carcinoma.

• KSBB Journal
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• v.21 no.1 s.96
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• pp.72-78
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• 2006

This study was carried out to investigate the antimicrobial and antioxidative effects of mycelium cultural extract from mushroom. Mushroom mycelium was grown in a defined synthetic liquid medium and citrus extracts, and the culture extracts were examined for antioxidant and antibacterial activity. Myceliums of Phellinus linteus, Cordyceps militaris, Coriolus versicolor, Sparassic crispa, Agaricus blazei, lnonotus obliquus, Lentinus edodes, Hericium erinacium, Gonoderma lucidium in 10% citrus extract supplemented medium and synthesis medium were incubated in a shaking incubator (120 rpm, $24{\sim}30^{\circ}C$ ) for $7{\sim}15$ days. The antimicrobial activity of the culture fluid of mushroom mycelium grown in submerged liquid culture was tested against 12 microorganisms which were fish pathogens and common bacterial species. The culture extracts showed high activity against Vibrio sp. and had poor effect on Streptocouus sp., S. parauberis, S. iniae. The culture extracts obtained from the synthetic medium showed $30{\sim}93%$ of the 1,1-diphenyl-2-picrylhydrazyl radical scavenger activity, the culture extracts obtained from the citrus extracts medium exhibited antioxidant activity up to 55%.

• Journal of The Korean Society of Grassland and Forage Science
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• v.31 no.3
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• pp.305-314
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• 2011

This study was conducted to investigate the effect of harvest stage of corn on the quality of gunny bag silage manufactured with corn grown in paddy land of Department of Animal Resources Development, National Institute of Animal Science, RDA from 2009 to 2010. Corn "Kwangpyungok" was harvested at three different growth stages (milk, yellow ripen and ripen stage) and ensiled at each harvest stages. The content of crude protein (CP) of corn in gunny bag silage decreased with delayed harvest maturity, but the contents of ADF (acid detergent fiber), NDF (neutral detergent fiber), TDN (total digestible nutrient) and in vitro dry matter digestibility (IVDMD) were not changed with delayed harvest maturity. The contents of moisture, pH, and the nutritive values at three different harvest stages were not influenced by the method of silage manufacture and inoculant. The content of lactate in corn bag silage at milk stage was significantly increased (P<0.05), as compared with that of round baled corn silage. However, The contents of lactate in corn bag silage at yellow ripen stage and ripen stage were significantly decreased (P<0.05). Flieg's score in corn bag silage manufactured at milk stage increased as compared with that of round baled corn silage, and Flieg's score was hardly influenced by inoculant. Therefore, we suggest that manufacture method of bag silage can be new silage technique to improve the fermentation of corn silage and that smallscale stock farmer could be substituted bag silage for roll bale silage on small farm land.

• Tuberculosis and Respiratory Diseases
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• v.58 no.5
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• pp.498-506
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• 2005

Background : This study compared the bronchodilator efficacy and safety of tiotropium inhalation capsules ($18{\mu}g$ once daily) with a ipratropium metered dose inhaler (2 puffs of $20{\mu}g$ q.i.d.) in patients with chronic obstructive pulmonary disease (COPD). Method : After the initial screening assessment and a two-week run-in period, patients received either tiotropium $18{\mu}g$ once daily or ipratropium $40{\mu}g$ four times daily over a period of 4 weeks in a double blind, double dummy, parallel group study. The outcome measures were the lung function, the daily records of the peak expiratory flow rate (PEFR), the patients' questionnaire, and the use of concomitant salbutamol. The forced expiratory volume in one second ($FEV_1$) and the forced vital capacity (FVC) were measured 5 minutes before inhalation, and 0.5, 1, 2 and 3 hours after inhaling the study drug on days 0, 14 and 28. Result : In 16 centers, 134 patients with a mean (SD) age of 66 (7) years and a predicted $FEV_1$ of 42 (12)% were analyzed. The trough $FEV_1$ response was significantly higher in the tiotropium group than in the ipratropium group after a four-week treatment period. The weekly mean morning PEFR of the tiotropium group was consistently higher than that of the ipratropium group during the 4-week treatment period with differences ranging from 12.52 to 13.88 l/min, which were statistically significant. Tiotropium was well tolerated by the COPD patients during the 4-week treatment period and had a similar safety profile to ipratropium. Conclusion : This study shows that tiotropium administrated once daily has a superior bronchodilator effect with a similar safety profile in treating COPD patients compared with ipratropium, inhaled four times daily.

• Journal of the Korean Geographical Society
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• v.30 no.3
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• pp.269-295
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• 1995

This research is concerned with the social division of labor within the traditional industry district: Damyang bamboo ware industry district and Yeoju pottery industry district in South Korea, Damyang bamboo ware and Yeoju pottery are well known of the Korean traditional industry. The social division of labor in an industry district is considered as an important factor. The social division of labor helps the traditional industry to survive today. This summary shows five significant points from the major findings. First, Damyang bamoo ware industry and Yoeju pottery industry have experienced the growth stages until 1945, the stagnation in the 1960s, and the business recovery in the 1980s. Most Korean traditional industries had been radically declined under the Japanese colonization; while, Damyang bamboo ware industry and Yeoju pottery industry district have been developed during above all stages. The extended market to Japan helped the local government to establish a training center, and to provide financial aids and technical aids to crafts men. During the 1960s and 1970s, mass production of substitute goods on factory system resulted in the decrease of demand of bamboo ware and pettery. During the 1980s, these industries have slowly recovered as a result of the increased income per capita. The high rate of economic growth in the 1960s and 1970s was playing an important role in the emerging the incleased demand of the bamboo ware and pottery. Second the production-and-marketing system in a traditional industry district became diversified to adjust the demand of products. In Damyang bamboo ware industry district, the level of social division of labor was low until the high economic development period. Bamboo ware were made by a farmer in a small domestic system, The bamboo goods were mainly sold in the periodic market of bamboo ware in Damyang. In the recession period in the 1960s and 1970s, the production-and-marketing system were diversified; a manufacturing-wholesale type business and small-factory type business became established; and the wholesale business and the export traders in the district appeared. In the recovery period in the 1980s, the production-and-marketing systems were more diversified; a small-factory type business started to depend On subcontractors for a part of process of production; and a wholesale business in the district engaged in production of bamboo ware. In Yeoju pottery industry district, the social division of labor was limited until the early 1970s. A pottery was made by a crafts man in a small-business of domestic system and sold by a middle man out of Yeoju. Since the late 1970s, production-and-marketing system become being diversified as a result of the increased demand in Japan and South Korea. In the 1970s, Korean traditional craft pottery was highiy demanded in Japan. The demand encouraged people in Yoeju to become craftsmen and/or to work in the pottery related occupation. In South Korea, the rapid economic growth resulted in incline to pottery due to the development of stainless and plastic bowls and dishes. The production facilities were modernized to provide pottery at the reasonable price. A small-busineas of domestic system was transformed into a small-factory type business. The social division of labor was intensified in the pottery production-and-maketing system. The manufacturing kaoline began to be seperated from the production process of pottery. Within the district, a pottery wholesale business and a retail business started to be established in the 1980s. Third the traditional industry district was divided into "completed one" and "not-completed one" according to whether or not the district firms led the function of the social division of labor. The Damyang bamboo ware industry district is "completed one": the firm within the district is in charge of the supply of raw material, the production and the marketing. In the Damyang bamboo ware district, the social division of labor w and reorganized labor system to improve the external economics effect through intensifying the social division of labor. Lastly, the social division of labor was playing an important role in the development of traditional industry districts. The subdivision of production process and the diversification of business reduced the production cost and overcame the labor shortage through hiring low-waged workers such as family members, the old people and housewives. An enterpriser with small amount of capital easily joined into the business. The risk from business recession were dispersed. The accumulated know-how in the production and maketing provided flexiblility to produce various goods and to extend the life-cycly of a product.d the life-cycly of a product.

• Journal of Life Science
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• v.19 no.4
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• pp.472-478
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• 2009

The purpose of this study was to evaluate the levels of blood lead and cadmium in urban and rural populations. Blood samples were collected from 100 urban (Busan) residents and 150 rural residents (Jinju-84, Gijang-66) from July 1 to August 30, 2007. The blood lead and cadmium levels were analyzed using flameless atomic absorption spectrophotometry and were compared by age, gender and smoking status. The mean levels of blood lead in urban-Busan, rural-Jinju and rural-Gijang residents were $6.38{\pm}2.86{\mu}g/dl$, $5.41{\pm}2.16{\mu}g/dl$ and $4.50{\pm}2.87{\mu}g/dl$, respectively. There was a significant difference in the level of blood lead between urban-Busan residents and rural-Gijang residents. The mean levels of blood cadmium in urban-Busan, rural-Jinju and rural-Gijang residents were $0.85{\pm}0.44{\mu}g/l$, $1.57{\pm}0.78{\mu}g/l$ and $0.95{\pm}0.54{\mu}g/l$, respectively. There was a significant difference in the level of blood cadmium between urban-Busan residents and rural-Jinju residents. This study showed that the levels of blood lead and cadmium were significantly different between urban and rural populations. The level of blood lead was highest in urban-Busan residents, but the level of blood cadmium was highest in rural-Jinju residents. Further studies are needed to define the cause of high levels of blood lead and cadmium related to area of residence and personal habits.

• Journal of Bio-Environment Control
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• v.21 no.3
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• pp.228-235
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• 2012

This study was carried out to investigate the effect of irrigation methods for reducing a drainage on the growth and yield in rockwool (Grodan co.) and cocopeat (chip : dust = 50 : 50 included fiber) culture. The nutrient solution was irrigated by $100J{\cdot}cm^{-2}$-100 mL, $50J{\cdot}cm^{-2}$-45 mL, $50J{\cdot}cm^{-2}$-40 mL, $50J{\cdot}cm^{-2}$-35 mL ($100{\sim}50J{\cdot}cm^{-2}$-100~35 mL, Nutrient solution 100~35 mL was irrigated per plant when the accumulated radiation was $100{\sim}50J{\cdot}cm^{-2}$). The drain rates per plant of 100-100, 50-45, 50-40, 50-35 were 26.3%, 8.8%, 6% 4.4% and 23.1%, 7.5%, 5% 3.4% in rockwool and cocopeat slabs. The water contents and EC of 100-100 and 50-45 were managed by the 55~70%, $3.0{\sim}5.0dS{\cdot}m^{-1}$ which were good condition for paprika culture in rockwool and cocopeat slabs, while those of 50-40 and 50-35 were managed by beyond 50%, $4.5{\sim}9.5dS{\cdot}m^{-1}$. The plant height, number of branches and leaf size of 100-100 and 50-45 were similarly increased while those of 50-40 and 50-35 were decreased. The fruit size and weight of 50-40 and 50-35 were small and light, while those of 100-100 and 50-45 were similarly big and heavy. The marketable fruits of 100-100 and 50-45 treatments were similarly more by 9.7~9.8 in rockwool and 8.8~8.9 in cocopeat, while the unmarketable fruits, the small and blossom end rot fruits were increased in 50-40 and 50-35 treatments. The yield of 100-100 and 50-45 treatments were similarly high.

• Pediatric Infection and Vaccine
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• v.14 no.1
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• pp.47-54
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• 2007

Purpose : Viral respiratory tract infection is most common cause for admission to hospital in children. There are many cases with elevated transaminase level in patients with viral lower respiratory tract infection (LRTI). The aim of this study was to compare indexes of disease severity such as duration of assisted ventilation, length of hospital stay and Respiratory Distress Assessment Instrument (RDAI) score in children with viral LRTI with and without elevated transaminase levels and to determine the etiology related to elevated transaminase levels in this patients group. Methods : Virological analysis was done from respiratory specimens obtained from patients with LRTI admitted to Kangnam Sacred Heart Hospital from Jan. 2003 to Jun. 2005. Viral diagnosis was made by isolation of viruses employing HEp-2 cell culture from nasopharyngeal aspiration. Medical records of children were reviewed retrospectively. We compared age, sex, RDAI score, Respiratory Rate (RR) score and mean duration of hospital stay between patients with elevated transaminase levels (Patient Group) and patients with normal transaminase levels (Control Group). Results : Viruses were isolated from 181 children with LRTI. 16 cases were excluded according to criteria. 28 cases (17.0%) had elevated transaminase levels (Patient group) and 137 cases (83.0%) had normal transaminase levels (Control group). There were no significant difference in duration of fever, RR score, RDAI score, incidence of $O_2$ inhalation and duration of hospital stay between patient group and control group. We found 17 (60.7%) cases of RSV, 4 cases (14.3%) of parainfluenza, 4 cases (14.3%) of influenza B virus, 3 cases (10.7%) of adenovirus and 1 case (3.6%) of influenza A virus infection in patient group and 78 cases (56.9%) of RSV, 28 cases (20.4%) of parainfluenza virus, 13 cases (9.5%) of influenza A virus, 9 cases (6.6%) of influenza B virus, 6 cases (4.4%) of adenovirus and 3 cases (2.2%) of coxsackie virus infection in control group. Conclusion : There were 28 cases (17.0%) with elevated transaminase level among patients with virus isolated LRTI. There was no relation between elevated transaminase level and severity of disease. The viral etiologies in two groups were not significantly different. There was no significant difference of age distribution between two groups.

• Journal of Bio-Environment Control
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• v.22 no.4
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• pp.355-360
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• 2013

Diesel-burning air heater (air heater) and infrared heating lamp (infrared heater) were installed as auxiliary heaters in two single water-curtained plastic greenhouses with a set night temperature of $6^{\circ}C$ for cultivation of strawberry 'Seolhyang'. The average night air temperature was $6.6^{\circ}C$ in the infrared heater treatment and $7.1^{\circ}C$ in the air heater treatment. However, when the minimum outside temperature fell below $-10^{\circ}C$, the air heater had less internal temperature fluctuations. In contrast, the infrared heater had some cases of falling below the set temperature. The relative humidity was higher than 98% by the side-effect of water-curtain system regardless of the heating system. There was about $5^{\circ}C$ difference in leaf temperature between the turned-on and -off state of the infrared heater, and the efficacy of the infrared heater on leaf temperature was only limited to about 4 meters from the system. Peduncle length and plant height in the infrared heater tended to be greater than those in the air heater. There was, however, no statistically difference in leaf size and numbers of leaves, flowers on first cluster and branches. There was no difference in soluble solids content, fruit firmness, average fruit weight of the harvested fruits, and the yield. Comparing the heating costs, the air heater system took 622,662 won based on 543 L tax-free diesel, while the infrared heater system took 235,284 won by consuming 5,685 kWh of electricity, and 62.2% heating costs saving was achieved.

• Atmosphere
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• v.25 no.1
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• pp.185-191
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• 2015

Ambient measurements of aerosol light absorption (${\sigma}_a$) and scattering coefficients (${\sigma}_s$) were done at Gosan climate observatory during summer 2008 using a 3-wavelength photoacoustic soot spectrometer (PASS). PASS was deployed photoacoustic method for light absorption and integrated nephelometry for light scattering measurements. The ${\sigma}_a$ and ${\sigma}_s$ from PASS were compared with those from co-located aethalometer and nephelometer measurements. The aethalometer measurements of ${\sigma}_a$ correlated reasonably well with photoacoustic measurements, but the slope of the linear fitting line indicated the PASS measurement values of ${\sigma}_a$ were larger by a factor of 1.53. The nephelometer measurement values of ${\sigma}_s$ correlated very well with PASS measurements of ${\sigma}_s$, with a slope of 1.12 and a small offset. Comparing to the aethalometer measurements, the photoacoustic measurements of ${\sigma}_a$ didn't exhibit a significant (i.e., the ratio between aethalometer and PASS increased) change with increasing relative humidity (RH). The ratio of ${\sigma}_s$ between nephelometer and PASS increased with increasing RH, especially when the RH increased beyond 80%. This apparent increase in ${\sigma}_s$ with RH may be due to the contribution of hygroscopic growth of aerosols.