• Title/Summary/Keyword: Malignant Tumor

Search Result 1,950, Processing Time 0.027 seconds

A Clinical Study of Parotid Gland Tumors (이하선 종양의 임상적고찰)

  • JeGal Young-Jong;Choi Wone
    • Korean Journal of Head & Neck Oncology
    • /
    • v.2 no.1
    • /
    • pp.33-39
    • /
    • 1986
  • This is a clinical analysis of 24 cases of parotid gland tumor who were treated in the department of Surgery, Chonnam National University Medical School during the past 10years from January, 1976 to December, 1985. According to this analysis of total 24 cases, we concluded as follows; 1) 21 cases were benign tumors and 3 cases were malignant tumors. As the histopathological findings, benign tumor included 88%and malignant tumor 12%. Majority of benign tumor contained mixed tumor(86.7%), and the malignant tumor contained mucoepidermoid carcinoma (66.7%). 2) The peak age incidence was 40th in benign tumor and 50th in malignant tumor. 3) The chief complaints of patient was a painless mass and the duration of illness was average 5.2 years. 4) The mean size of mass was 4.5cm in diameter. 5) The surgical procedures were performed with excision 6 cases, superficial lobectomy 8 cases, wide excision with partial parotidectomy 4 cases, total parotidectomy 3 cases in benign tumors. In malignant tumors, total parotidectomy 2 cases and wide excision with partial parotidectomy 1 case were performed. 6) Major postoperative complications such as facial nerve palsy 7 cases (temporary ; 5 cases, permanent; 2 cases), Frey syndrome 1 case, seroma 1 case, hematoma 1 case, and wound infection 1 case were developed. The recurrence contained pleomorphic adenoma 1 case and mucoepidermoid carcinoma 1 case.

  • PDF

A Computer Aided Diagnosis Algorithm for Classification of Malignant Melanoma based on Deep Learning (딥 러닝 기반의 악성흑색종 분류를 위한 컴퓨터 보조진단 알고리즘)

  • Lim, Sangheon;Lee, Myungsuk
    • Journal of Korea Society of Digital Industry and Information Management
    • /
    • v.14 no.4
    • /
    • pp.69-77
    • /
    • 2018
  • The malignant melanoma accounts for about 1 to 3% of the total malignant tumor in the West, especially in the US, it is a disease that causes more than 9,000 deaths each year. Generally, skin lesions are difficult to detect the features through photography. In this paper, we propose a computer-aided diagnosis algorithm based on deep learning for classification of malignant melanoma and benign skin tumor in RGB channel skin images. The proposed deep learning model configures the tumor lesion segmentation model and a classification model of malignant melanoma. First, U-Net was used to segment a skin lesion area in the dermoscopic image. We could implement algorithms to classify malignant melanoma and benign tumor using skin lesion image and results of expert's labeling in ResNet. The U-Net model obtained a dice similarity coefficient of 83.45% compared with results of expert's labeling. The classification accuracy of malignant melanoma obtained the 83.06%. As the result, it is expected that the proposed artificial intelligence algorithm will utilize as a computer-aided diagnosis algorithm and help to detect malignant melanoma at an early stage.

A Large Malignant Peripheral Nerve Sheath Tumor in the Neurofibromatosis Patient: A Case Report (신경섬유종증 환자에 발생한 거대 악성말초신경초종의 치험례)

  • Choi, Dong Il;Seo, Dong Kuk;Jo, Woo Sung;Chung, Chul Hoon;Cho, Seong Jin
    • Archives of Plastic Surgery
    • /
    • v.33 no.6
    • /
    • pp.761-763
    • /
    • 2006
  • Purpose: Malignant peripheral nerve sheath tumors most often arise from the anatomically discernible peripheral nerve or neurofibroma. Methods: A 55-year-old man had a rapidly growing pedunculated large mass on the sacrolumbar junction for 2 years. He has congenital neurofibromatosis type I. He had multiple caf-au-lait spots and multiple neurofibromas on the entire body. The mass developed from a subcutaneous nodule on the sacrolumbar junction and grew rapidly. The preoperative punch biopsy revealed a malignant peripheral nerve tumor. The mass was completely excised with 1 cm free margin above the deep fascial plane. Results: There was no evidence of recurrence of tumor for 19 months of follow-up examination. Conclusion: Malignant peripheral nerve sheath tumor is very rare and has unique feature. We report a successful case of malignant peripheral nerve sheath tumor with the review of the literatures.

A Case of Malignant Triton Tumor on Supraclavicular Area (쇄골 상부에 발생한 악성 Triton 종양 1예)

  • Lim, Sang Ho;Park, Hee Tack;Hong, Ki Hwan
    • Korean Journal of Head & Neck Oncology
    • /
    • v.29 no.2
    • /
    • pp.54-57
    • /
    • 2013
  • Malignant triton tumor(MTT) is a rare type of malignant peripheral nerve sheath tumor(MPNST) with focal rhabdomyoblastic differentiation. MTT constitutes about 5% of all MPNSTs and described the first case of a MTT in a patient with Von Recklinghausen disease by Masson in 1932. MTT is commonly seen in the head, neck, extremities and trunk. It can occur in sporadic form or over a setting of neurofibromatosis-1(NF-1). The diagnosis can be confirmed based on morphologic grounds supported by an immunostain such as S-100 protein. Desmin, myo-D1 and myogenin are immunostains positive for rhabdomyoblasts. MTT has an aggressive biological behavior so prognosis of this rare and highly malignant tumor is poor and optimal treatment remains unclear. But modern treatment consisted of radical excision and postoperative radiotherapy has improved the prognosis of such cases.

Non-Functioning, Malignant Pancreatic Neuroendocrine Tumor in a 16-Year-old Boy: A Case Report (16세 남아에서 발생한 췌장의 비기능성 악성 신경내분비 종양: 증례 보고)

  • Lim, Se-Woong;Lee, Young-Hwan;Choi, See-Sung;Cho, Hyun-Sun
    • Investigative Magnetic Resonance Imaging
    • /
    • v.14 no.2
    • /
    • pp.145-150
    • /
    • 2010
  • We report the case of a 16-year-old boy with a solid pancreatic mass which proved to be a nonfunctioning, malignant pancreatic neuroendocrine tumor (PNET). In pediatric patients, malignant pancreatic tumors are rare, especially malignant PNET. When dynamic contrast enhanced MRI showed a well enhancing solid pancreatic tumor on arterial and delayed phases and combined with malignant features, such as vascular invasion, invasion of adjascent organs, and lymphadenopathy, we should include malignant pancreatic neuroendocrine tumor in the differential diagnosis of childhood pancreatic tumors.

A Case of Malignant Rhabdoid Tumor in the Anterior Mediastinum (전종격동에서 발생한 악성 횡문근양 종양 1예)

  • Oh, Kyung Jin;Lee, Ki Byung;Hong, Soon Won;Jung, Kyo Tae;Choi, Hong Kyu;Kim, Hyung Jung;Ahn, Chul Min;Chang, Yoon Soo
    • Tuberculosis and Respiratory Diseases
    • /
    • v.67 no.5
    • /
    • pp.462-466
    • /
    • 2009
  • Malignant rhabdoid tumors arise primarily from the kidney. Extrarenal malignant rhabdoid tumors are rare, with the liver, central nervous system, and skin reported as the primary sites. Malignant rhabdoid tumors of the mediastinum are extremely rare among extrarenal malignant rhadoid tumors; only 3 cases have been reported to date, all characterized by aggressive clinical behavior. We experienced a 35-year-old woman diagnosed with malignant rhabdoid tumor in the anterior mediastinum with multiple metastases. The tumor was surgically unresectable, and treated with palliative radiation therapy. Three-month after radiation treatment, she died from dissemination of the malignant rabdoid tumor.

Malignant Tumor of the Hand (수부에 발생한 악성 종양)

  • Park, Hong-Jun;Shin, Kyoo-Ho;Bae, Im-Don;Hahn, Soo-Bong;Kang, Eung-Shick
    • The Journal of the Korean bone and joint tumor society
    • /
    • v.5 no.4
    • /
    • pp.201-207
    • /
    • 1999
  • Malignant tumors of the hand are very rare. Between 1989 and 1998, 17 patients with malignant tumors of the hand were evaluated for clinical features, prevalence, treatment and results. The mean age was 45 years and median duration of follow-up was 38 months. A painless mass was the most common symptom and the most common lesion was the digit. Fifteen cases of soft tissue and 2 cases of bone tumor were diagnosed. On pathology, soft tissue tumors were comprised of 8 cases of malignant melanoma, 2 cases of angiosarcoma and 1 case each of malignant fibrous histiocytoma, malignant peripheral nerve sheath tumor, extraskeletal chondrosarcoma, and squamous cell carcinoma. Bone tumors were metastatic tumors and each originated from the rectal cancer or lung cancer. Lymph node involvements were noted in 4 cases of malignant melanoma and 1 case of squamous cell carcinoma. Six cases of metacarpo-phalangeal joint disarticulation and 4 cases of phalanx amputation were performed. Wide excision, ray amputation and below-elbow amputation were also performed. Three cases expired due to metastasis and progression of the original lesion. Among the surviving 14 cases, a malignant melanoma had metastasis on the axillary lymph node and 13 cases showed no local recurrence or metastasis during the follow-up.

  • PDF

Malignant Mixed Tumor of Salivary Glands: A Clinical Study (악성 혼합종의 임상적 고찰)

  • Oh Kyung-Kyoon;Lee Guk-Haeng;Lee Jong-Ho;Shim Yoon-Sang
    • Korean Journal of Head & Neck Oncology
    • /
    • v.9 no.2
    • /
    • pp.227-233
    • /
    • 1993
  • For malignant neoplasms of salivary tissues. two of the better determinants of progosis are histologic classification and size of the neoplasm. Proper management of these tumors requires an accurate diagnosis by the pathologist and correct interpretation by the surgeon. Malignant mixed tumors account for between 3 and 13 precent of all cancers of the salivary glands and 2 percent of all tumors in these locations. The typical history of these tumors is that of slowly growing mass demonstrating a sudden increase in growth. The duration of onset of the tumor mass and the diagnosis of malignancy has been demonstrated to be 10 to 18 years. The risk of malignat transformation of a benign mixed tumor increases with the duration of the tumor. We analyzed retrospectively 13 cases of malignant mixed tumor who visited from Jan. 1985 to Dec. 1992. Mean age of the patients was 56.5 years. The origin of tumors were parotid gland 7 cases, submandibular gland 2 cases, and minor salivary gland 4 cases(palate 3 cases, tonsil pillar 1 case). According to the criteria of the AJCC on staging, stage I was 1 case, stage II 1 case, stage III 2 cases, and stage IV 9 cases. Histopathologically, carcinma ex pleomorphic adenoma were 12 cases and the true malignant mixed tumor was 1 case. The major treatment modalities were curative surgery, and radiation therapy followed. In conclusion, aggressive therapy of combined surgery and postoperative radiation therapy is required for these lesions, and patients with known or suspected benign tumor should be encouraged to undergo surgery early on in their disease to avoid malignant degeneration at a later dete.

  • PDF

Malignant Proliferating Trichilemmal Tumor - A Case Report - (악성 증식성 모낭 종양 - 증례 보고 -)

  • Hong, Ki-Do;Kim, Jae-Young;Ha, Sung-Sik;Sim, Jae-Chun;Cho, Hye-Jae;Choi, Yoon-Ho
    • The Journal of the Korean bone and joint tumor society
    • /
    • v.15 no.1
    • /
    • pp.65-68
    • /
    • 2009
  • Proliferating trichilemmal tumor(PTT) is a rare neoplasm derived from the outer root sheath of the hair follicle. Malignant transformation is rare, but abrupt enlargement of size, infiltrative growth, and non-scalp location are suggestive of malignant PTT. Histopathologic characteristics of malignant PTT are nuclear atypia, pleomorphism, and mitotic figures. Recurrence and metastasis have been documented in malignant PTT. Wide resection of the tumor with the normal tissue and accurate follow-up is the treatment of choice of the both malignant and benign PTT. We report a 51-year-old man with the mass on right 5th finger distal phalanx for 7 years. The tumor was excised with middle phalangiectomy, and based on the histopathologic findings of the tumor, this case was diagnosed as mailignant PTT. We cannot detect recurrence and metastasis because the patient was lost to follow-up.

  • PDF

Imaging Findings of a Malignant Rhabdoid Tumor in the Stomach: A Case Report (위에 발생한 악성 횡문근양 종양의 영상 소견: 증례 보고)

  • Hye Ran Yoon;Dong Hee Park;Joonseog Kong
    • Journal of the Korean Society of Radiology
    • /
    • v.82 no.2
    • /
    • pp.493-497
    • /
    • 2021
  • A malignant rhabdoid tumor is an aggressive tumor that occurs mainly in the kidney of infants and children. When it occurs in extrarenal sites, it is referred to as an extrarenal malignant rhabdoid tumor. Although a few cases of malignant rhabdoid tumor occuring in the central nervous system, liver, brain, skin, and soft tissue have been reported, it is rarely observed in the stomach. We report the imaging findings of a malignant rhabdoid tumor of the stomach that mimicked a gastric lymphoma in a patient who presented with melena.