• Asian Pacific Journal of Cancer Prevention
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• v.16 no.9
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• pp.3779-3783
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• 2015

Dietary prevention has been known to reduce breast cancer risk. Sesamin is one of the major components in sesame seeds and has been widely studied and proven to have anti-proliferation and anti-angiogenic effects on cancer cells. In this study, the influence of sesamin was tested in the human breast cancer MCF-7 cell line for cell viability (MTT assay) and cell cycling (flow cytometry). Results showed that sesamin dose-dependently (1, 10 and $50{\mu}M$) reduced the cell viability and increased LDH release and apoptosis (TUNEL assay). In addition, there was a significant increase of sub-G1 phase arrest in the cell cycle after sesamin treatment. Furthermore, sesamin increased the expression of apoptotic markers of Bax, caspase-3, and cell cycle control proteins, p53 and checkpoint kinase 2. Taken together, these results suggested that sesamin might be used as a dietary supplement f or prevention of breast cancer by modulating apoptotic signal pathways and inhibiting tumor cell growth.

• Proceedings of the SAREK Conference
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• 2009.06a
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• pp.108-113
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• 2009

Buildings with multi-complex spaces designed for architectural values and functional requirements give rise to technical challenges in terms of energy efficiency and thermal comfort. Since spaces in such buildings are connected with openings with geometrical complexity, it is hard to define zoning plan and to control heating/cooling loads effectively. This paper presents a case study on the evaluation of operation strategy for a building with multi-complex spaces using computer simulation. The modelling methodology and the results of the simulations are also described.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.64 no.7
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• pp.1019-1025
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• 2015

The performance requirements on the safety-based functionality of railway signal systems have been reinforced and the effort for enhancement of the existing system or development of the new system is being accordingly made. In particular, various technical researches on replacement or improvement of the existing ATS(Automatic Train Stop) signaling system are now in progress for better operational efficiency. In this study, the complementary points for improvement or replacement of the currently used system(i.e., ATS) will be derived in terms of operating efficiency in an integrated operating environment with the newly introduced system(e.g., ATC: Automatic Train Control). This study can contribute to derive the need for improvement of the signaling system by checking the interface problems and comparing between different systems through the analysis of real operation cases in the field. Eventually, this analysis can be applied to prevent and estimate the collision accidents can be caused by the failure of the signaling system in advance. In addition, the results can be used to provide a future direction to secure the reliability in the parallel operation by integration based on different railway signaling systems.

• Journal of the Korea Concrete Institute
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• v.21 no.5
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• pp.649-660
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• 2009

A nonlinear column model of an internally confined hollow (ICH) reinforced concrete (RC) column was suggested and a parametric study was performed. The suggested column model considered the confining effect and the material nonlinearity of concrete. To verify the suggested column model, its analysis results were compared with the test results from previous researchers and a quasi static test performed in this study. They showed that the suggested column model was reasonable and had acceptable accuracy. The results from parametric studies showed that the thickness of the internal tube, concrete strength, and the hollow ratio of the ICH RC column affected its behavior.

• Korean Journal of Human Ecology
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• v.20 no.6
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• pp.1223-1228
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• 2011

This study was done to investigate the content of sodium saccharin in Kimchi and salted vegetables served by restaurants. 99 samples were collected from restaurants which were located mainly in the Seoul metro area. Sodium saccharin was analyzed by HPLC. The types of restaurants were privately owned(68.7%) and franchised(31.3%). The composition ratio of sodium saccharin in Kimchi & salted vegetables at Korean, Chinese, Japanese, fast food, family, flour based food, and buffet restaurants was 60%, 14%, 2%, 7%, 13%, 4%, respectively. The composition ratio of sodium saccharin in kaktugi,, danmooji, kimchi, moosangchai, jangajji, mool kimchi, pickle, jjasai, oijii was 19.2%, 16.2%, 16.2%, 14.1%, 12.1%, 9.1%, 5.1%, 4.0%, 4.0% respectively. The mean of sodium saccharin detection rate of the 99 samples was 30.30%.

• Korean Journal of Health Education and Promotion
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• v.30 no.5
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• pp.139-151
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• 2013

Objectives: This study investigated how income, duration of illness, social stigma, quality of sleeping, ADL and social participation related to Parkinson's disease(PD) predict depression in a conceptual model based on the International Classification of Functioning(ICF) model. Methods: The sample included 206 adults with idiopathic Parkinson's disease(IPD) attending D university hospital in B Metro-politan City. A structured questionnaire was used and conducted face-to-face interviews. The collected data were analyzed for fitness, using the AMOS 18.0 program. Results: A path analysis showed that the overall model provided empirical evidence for linkages in the ICF model. Depression was manifested by significant direct effects of social stigma(${\beta}=.20$, p<.001), quality of sleeping(${\beta}=-.40$, p<.001), ADL(${\beta}=-.20$, p<.01), and social participation(${\beta}=-.12$, p<.05), indirect effects including income(p<.05), duration of illness(p<.05). These variables explained 45.9% of variance in the prediction model. Conclusions: This model may help nurses to collect and assess information to develop intervention program for depression.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2016.05a
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• pp.496-498
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• 2016

The current domestic subway has been conducting specialized transportation seats, aimed at whomever wish to use metro not only for vulnerable and disabled people but also for 'pregnant women', which mostly concerns for women during their pregnancy. However so far, such measures have not shown to be effective enough for the community to consider pregnant women as 'weaker transportation users'. Therefore, this paper announces a new seat arrangement system proposal for these specialized seats to be exerting advantageous influences for pregnant women. The grounds for this proposal are using "Hybrid Beacon", which is a short-range communication technology, and combining this to the Mobile Application. The proposal starts with observing the current problem related to the specialized seats for pregnancy, and follows by the concept of the system and the scenario.

• Journal of Electrical Engineering and Technology
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• v.13 no.1
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• pp.105-113
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• 2018

This paper proposes pre-analysis on planning of high-voltage direct current (HVDC) transmission system applied to Korea electric power grid. HVDC transmission system for interface lines has been considered as alternative solution for high-voltage AC transmission line in South Korea since constructing new high-voltage AC transmission lines is challenging due to political, environmental and social acceptance problems. However, the installation of HVDC transmission system as interface line in AC grid must be examined carefully. Thus, this paper suggests three scenarios to examine the influences of the installation of HVDC transmission system in AC grid. The power flow and contingency analyses are carried out for the proposed scenarios. Power reserves in metro area are also evaluated. And then the transient stability analysis focusing on special protection scheme (SPS) operations is analyzed when critical lines, which are HVDC lines or high voltage AC lines, are tripped. The latest generic model of HVDC system is considered for evaluating the impacts of the SPS operations for introducing HVDC system in the AC grid. The analyses of proposed scenarios are evaluated by electromechanical simulation.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.67 no.5
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• pp.688-694
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• 2018

The transition section of the overhead rigid conductor rail (ORCR) consists of a direct induction device and a limit point to prevent the power supply failure and failure of the electric railway vehicle pantograph due to the difference of the uplift in the catenary line. In T-Bar transition section, a twin simple catenary is mostly installed between the overhead catenary system (OCS) in the ground section and the ORCR in the underground section. In this paper, we compare and analyze the possibility of replacing the twin simple catenary with heavy simple catenary. The reliability of numerical analysis results was confirmed by comparing field test with numerical results. Comparing the numerical results of the twin simple catenary with the heavy simple catenary in the transition section, the difference uplift is 5.9[mm] on average. When applying heavy simple catenary instead of twin simple catenary, the slight difference of uplift can be compensated by adjusting the height of hanger-ear or support bracket.

• Geomechanics and Engineering
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• v.15 no.2
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• pp.769-774
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• 2018

The growth of cities requires the construction of new tunnels close to the existing ones. Prediction and control of ground movement around the tunnel are important especially in urban area. The ground respond due to EPB (Earth Pressure Balance) pressure are investigated using the finite element method by ABAQUS in intersection of the triplet tunnels (Line 2, 3 and 4) of Mashhad Urban Railway in Iran. Special attention is paid to the effect of EPB pressure on the tunnel face displacement. The results of the analysis show that in EPB tunneling, surface settlement and face displacement is related to EPB pressure. Moreover, it is found that tunnel construction sequence is a great effect in face displacement value. For this study, this value in Line 4 where is excavated after line 3, is smaller than that line. In addition, the trend of the displacement curves are changed with the depth for all lines where is located in above and below, close to and above the centerline tunnel face for Line 2, 3 and 4, respectively. It is concluded that: (i) the surface settlement decreases with increasing EPB pressure on the tunnel face; (ii) at a constant EPB pressure, the tunnel face displacement values increase with depth. In addition, this is depended on the tunneling sequence; (iii) the trend of the displacement curves change with the depth.