• Title/Summary/Keyword: MD4

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Quality Characteristics of Ginseng Powder using Molecular Press Dehydration Method (분자 압축 탈수방법을 이용한 인삼분말의 품질특성)

  • Lee, H.S.;Kwon, K.H.;Jeong, J.W.
    • Journal of Biosystems Engineering
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    • v.34 no.3
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    • pp.155-160
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    • 2009
  • This study was attempted to quality characteristics of ginseng powder using molecular press dehydration(MD) method. Ginseng powder was dried using maltodextrin as dehydrating agents, and the quality of the ginseng powder was compared with that of freeze-drying and hot air-drying samples in terms of colors, moisture contents and grain size. The colors of ginseng powder using MD-drying and freeze-drying was better than hot air-dried ginseng powder. The moisture contents of ginseng powder using MD-drying was 9.49%, while freeze-drying was 4.14% and hot air-drying 11.71% after 72ball mill times. The grain size of ginseng powder using MD-drying and freeze-drying was better than hot air-drying ginseng powder. These results suggest that drying of ginseng powder using molecular press dehydration method is very efficient, because minimal cell destruction may be achieved.

Confirmation Method of Target Detection for Vehicle Mounted Metal Detector

  • Jung, Byung-Min;Shin, Beom-Su;Chang, YuShin;Yang, DongWon
    • Journal of the Korea Society of Computer and Information
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    • v.21 no.10
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    • pp.49-54
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    • 2016
  • In this paper, the confirmation method of target detection for the vehicle mounted metal detector (MD) has been described. The vehicle mounted MD with the arrayed 6 coils to detect the width of 2.4 m was demonstrated. It is important and necessary to inform the location of the objects detected by the MD. The confirmation method of target detection was verified by using the MD GUI and the analysis of the receive signal processing. The receive signal processing is performed by comparing the threshold and the difference of the signal calibrated at initial location and the signal detected at present location.

Intramolecular Hydrogen Bonds in Proteinase Inhibitor Protein, A Molecular Dynamics Simulation Study

  • Chung, Hye-Shin
    • BMB Reports
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    • v.29 no.4
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    • pp.380-385
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    • 1996
  • Ovomucoid third domain is a serine proteinase inhibitor protein which consists of 56 amino acid residues. A fifty picosecond molecular dynamics (MD) simulation was carried out for ovomucoid third domain protein with 5 $\AA$ layer of water molecules. A comparison of main chain atoms in the MD averaged structure with the crystal structure showed that most of the backbone structures are maintained during the simulation. Investigation of the intramolecular hydrogen bondings indicated that most of the interactions between main chain atoms were conserved, whereas those between side chains were reorganized for the period of the simulation. Especially, the side chain interactions around the scissile bond of reactive site P1 (Met18) were found to be more extensive for the MD structures. During the simulation, hydrogen bonds were maintained between the side chains of Glu19 and Arg21 as well as those of Thr17 and Glu19. Extensive side chain interactions observed in the MD structures may shed light on the question of why protein proteinase inhibitors are strong inhibitors for proteinases rather than good substrates.

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The Mechanism : Hydrolysis of Formamide

  • Baek, Yong-Su;Choe, Cheol-Ho
    • Proceeding of EDISON Challenge
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    • 2015.03a
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    • pp.91-98
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    • 2015
  • Formamide의 중성가수분해 mechanism은 QM/MM (quantum mecahnics/molecular mechanics) molecular dynamics simulations 및 CPMD과 같은 방법으로 연구되어왔다. 본 연구에서는. Umbrella sampling을 이용한 QM/MM-MD simulation을 사용하여 4가지 반응의 free energy surface를 도출해냈다. 전체적으로, 가장 선호되는 메커니즘은 two step으로 구성된 water assisted stepwise mechanism이었으며 모든 mechanism은 ab-initio calculation과 QM/MM-MD simulation이 수행되었다. water assisted stepwise mechanism을 살펴보면, 첫 번째 step에서 formamide의 carbonyl group이 hydrate되면서 gem-diol intermediate를 형성한다. 다음 step에서, intermediate의 hydroxyl group으로부터 amino group으로 water-assisted proton transfer이 일어난다. 두 반응 모두에서 물이 proton transfer를 직접적으로 도와주는 것을 관찰할 수 있었다. 특히, ab-initio calculation과는 다르게 QM/MM-MD에서는 gem-diol intermediate가 안정화되는 것으로 solvent effect를 잘 보여준다.

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The antibacterial effect of Endoseal TCS mixed with water-soluble mangostin derivatives of Garcinia mangostana L. ethanol extract against Enterococcus faecalis and Staphylococcus aureus

  • Park, Tae-Young;Lim, Yun Kyong;Kim, Jin-Hee;Lee, Dae Sung;Kook, Joong-Ki
    • International Journal of Oral Biology
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    • v.46 no.1
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    • pp.45-50
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    • 2021
  • This study evaluated the antimicrobial activity of Endoseal TCS, an mineral trioxide aggregate-based root canal sealer, mixed with water-soluble mangostin derivatives (WsMD) of Garcinia mangostana L. (mangosteen) ethanol extract against Enterococcus faecalis and Staphylococcus aureus. The antibacterial activity of Endoseal TCS mixed with WsMD against three strains of E. faecalis and three strains of S. aureus was performed using agar diffusion test. The data showed that Endoseal TCS mixed with 0.115% WsMD had a zone of inhibition of 0.7 ± 0.2-2.4 ± 0.1 mm. The results suggest that Endoseal TCS mixed with WsMD of Garcinia mangostana L. ethanol extract is useful as a root canal sealer with antibacterial activity against E. faecalis and S. aureus.

Repeated-Dose Toxicity Study of Pediococcus pentosaceus MD1, an Anti-Helicobacter pyroli Activity Lactic Acid Bacteria Isolated from Kimchi, in Rats (김치로부터 분리한 Helicobacter pyroli 억제능 유산균 Pediococcus pentosaceus MD1의 흰쥐에 대한 반복투여독성 연구)

  • Lee, Jae-Joon;Lee, Yu-Mi;Chang, Hae-Choon;Lee, Myung-Yul
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.36 no.8
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    • pp.975-982
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    • 2007
  • The purpose of this study was to investigate repeated-dose toxicity in male and female rats orally administered with Pediococcus pentosaceus MD1, an anti-Helicobacter pyroli producing lactic acid bacteria isolated from kimchi. Sprague-Dawley rats were divided into 4 groups, 10 animals in each group. The test article was administered once daily by gavage to rats at dose levels of 0, 500, 1,000 and 2,000 mg/kg for 4 weeks. No test article-related deaths and clinical findings in both sexes of rats during the study period were resulted. In addition, no differences were found between control and treated groups in body weight changes, food intake consumption and water consumptions. Hematological parameters, serum biochemical analysis and any other findings did not also show any significant or dose-dependent alterations. There were no alterations in absolute and relative organ weights by the administration of Pediococcus pentosaceus MD1. These results suggest that no-observed-adverse-effect level (NOAEL) of Pediococcus pentosaceus MD1 is considered to be more than 2 g/kg in male and female rats.

Implementing Cipher APIs in Inter IXP 2400

  • Lee, Sang-Su;Han, Min-Ho;Kim, Jeong-Nyeo
    • 제어로봇시스템학회:학술대회논문집
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    • 2005.06a
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    • pp.374-376
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    • 2005
  • In this paper, we presented our implementation of 3DES and HMAC-MD5 processing functionality in Intel? IXP 2400 platform. It can be used as encryption and authentication engine for VPNs such as IPsec and SSL.

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Determination of Plasmids Encoding Crystal Toxic Protein Gene in Bacillus thuringiensis var kurstaki HD-1 (Bacillus thuringiensis var kurstaki HD-1의 내독소 단백질 유전에 관여하는 plasmid의 결정)

  • 김철영;김상현
    • Journal of Sericultural and Entomological Science
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    • v.35 no.2
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    • pp.120-128
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    • 1993
  • The objective of this study is to identify plasmids of Bacillus thuringiensis var. kurstaki HD-1(B. t k HD-1) toxic to lepidopteran larvae. The results from agarose gel electrophoresis indicated that the bacterium contained 9 plasmids with approximate sizes of 1.4, 4.9, 5.4, 9.3, 10, 29, 44, 52, and 150 megadaltons(Md). By treating the wild type of B. t k HD-1 with either SDS or EtBr as curing agent, 26 cured mutants of the bacterium were obtained, 9 of them were crystallifereous(cry+) and the others acrystallifereous(cry-). Plasmids from B. t k HD-1 were transferred to B. cereus 569 strR cry- recipients(Bc569 M1). Among 13 isolates of Bc569 M1 transcipient, 11 of them were capable of producing the crystal toxic proteins. The plasmid patterns of Bc569 M1 transcipients and partially curved mutants of B. t k HD-1 on agarose gel electrophoresis suggested that the 29 and 44Md plasmids should be involved in the production of crystalline toxic proteins.

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A Study on Design and Fabrication of Quad-Band Small Antenna with MD(magneto-dielectric) material for mobile Applications (MD 매질을 이용한 이동통신용 Quad-Band 소형 안테나 설계 및 구현에 관한 연구)

  • Kim, Woo-Su;Yoon, Cheol;Oh, Soon-Soo;Kang, Suk-Youb;Park, Hyo-Dal
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.14 no.5
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    • pp.1270-1276
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    • 2010
  • In this paper, Quad-Band small antenna for GSM850, GSM900, DCS1800, DCS1900 is designed and fabricated. The antenna achieved the size reduction of over 67.9 % than the conventional PIFA(Planar Inverted-F Antenna) by using a MD(Magneto-Dielectric) material. A simple feeding microstrip line is used to feed the antenna from a $50{\Omega}$ coaxial line, which is capacitively coupled to the grounded patch structure for broadband characteristics. The impedance bandwidth the proposed antenna shows good results as broadband characteristics of 1341 MHz (801 ~ 2142 MHz) in VSWR < 3 (${\leq}\;-6\;dB$) and the gain is -6.67 ~ 4.25 dBi in the operating frequency.

Driving Per Nozzle By Various Waveform Depending On Resonance Frequency In Piezoelectric Inkjet Head (잉크젯 헤드의 공진주파수에 따른 구동파형을 이용한 개별노즐 제어)

  • Kim, Y.J.;Park, C.S.;Sim, W.C.;Kang, P.J.;Yoo, Y.S.;Park, J.H.;Joung, J.W.;Oh, Y.S.
    • Proceedings of the KIEE Conference
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    • 2007.07a
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    • pp.1542-1543
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    • 2007
  • This paper presents the effect of driving waveform for piezoelectric bend mode inkjet printhead with optimized mechanical design. Experimental and theoretical studies on the applied driving waveform versus jetting characteristics were performed. The inkjet head has been designed to maximize the droplet velocity, minimize voltage response of the actuator and optimize the firing frequency to eject ink droplet. The head design was carried out by using mechanical simulation. The printhead has been fabricated with Si(100) and SOI wafers by MEMS process and silicon direct bonding method. To investigate how performance of the piezoelectric ceramic actuator influences on droplet diameter and droplet velocity, the method of stroboscopy was used. Using the water based ink of viscosity of 11.8 cps and surface tension of 0.025N/m, it is possible to eject stable droplets through 64 nozzles average velocity of 4.05 m/s with standard deviation of 0.06 m/s and average diameter of $29.2\;{\mu}m$ with standard variation of $0.5\;{\mu}m$.

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