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The antibacterial effect of Endoseal TCS mixed with water-soluble mangostin derivatives of Garcinia mangostana L. ethanol extract against Enterococcus faecalis and Staphylococcus aureus

  • Park, Tae-Young (Department of Conservative Dentistry, Chosun University) ;
  • Lim, Yun Kyong (Korean Collection for Oral Microbiology, Chosun University) ;
  • Kim, Jin-Hee (Department of Oral Biochemistry, School of Dentistry, Chosun University) ;
  • Lee, Dae Sung (Medi Bio Lab Co., Ltd.) ;
  • Kook, Joong-Ki (Korean Collection for Oral Microbiology, Chosun University)
  • Received : 2021.01.25
  • Accepted : 2021.03.19
  • Published : 2021.03.31

Abstract

This study evaluated the antimicrobial activity of Endoseal TCS, an mineral trioxide aggregate-based root canal sealer, mixed with water-soluble mangostin derivatives (WsMD) of Garcinia mangostana L. (mangosteen) ethanol extract against Enterococcus faecalis and Staphylococcus aureus. The antibacterial activity of Endoseal TCS mixed with WsMD against three strains of E. faecalis and three strains of S. aureus was performed using agar diffusion test. The data showed that Endoseal TCS mixed with 0.115% WsMD had a zone of inhibition of 0.7 ± 0.2-2.4 ± 0.1 mm. The results suggest that Endoseal TCS mixed with WsMD of Garcinia mangostana L. ethanol extract is useful as a root canal sealer with antibacterial activity against E. faecalis and S. aureus.

Keywords

References

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