• 시스템엔지니어링학술지
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• 제19권2호
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• pp.18-31
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• 2023

Exploring artificial intelligence and machine learning for nuclear safety has witnessed increased interest in recent years. To contribute to this area of research, a machine learning model capable of accurately predicting nuclear power plant response with minimal computational cost is proposed. To develop a robust machine learning model, the Best Estimate Plus Uncertainty (BEPU) approach was used to generate a database to train three models and select the best of the three. The BEPU analysis was performed by coupling Dakota platform with the best estimate thermal hydraulics code RELAP/SCDAPSIM/MOD 3.4. The Code Scaling Applicability and Uncertainty approach was adopted, along with Wilks' theorem to obtain a statistically representative sample that satisfies the USNRC 95/95 rule with 95% probability and 95% confidence level. The generated database was used to train three models based on Recurrent Neural Networks; specifically, Long Short-Term Memory, Gated Recurrent Unit, and a hybrid model with Long Short-Term Memory coupled to Convolutional Neural Network. In this paper, the System Engineering approach was utilized to identify requirements, stakeholders, and functional and physical architecture to develop this project and ensure success in verification and validation activities necessary to ensure the efficient development of ML meta-models capable of predicting of the nuclear power plant response.

• Structural Engineering and Mechanics
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• 제20권2호
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• pp.173-189
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• 2005

The paper presents a finite element model for studying timber-concrete composite beams under long-term loading. Both deformability of connection system and rheological behaviour of concrete, timber and connection are fully considered. The creep of component materials and the influence of moisture content on the creep of timber and connection, the so-called "mechano-sorptive" effect, are evaluated by means of accurate linear models. The solution is obtained by applying an effective step-by-step procedure in time, which does not require storing the whole stress history in some points in order to account for the creep behaviour. Hence the proposed method is suitable for analyses of composite beams subjected to complex loading and thermo-hygrometric histories. The possibility to accurately predict the long-term response is then shown by comparing numerical and experimental results for different tests.

• Biotechnology and Bioprocess Engineering:BBE
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• 제8권1호
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• pp.23-31
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• 2003

A mathematical model was formulated to simulate the long-term performance of an anaerobic bioreactor designed to digest Korean food wastes. The system variables of various decomposition steps were built into the model, which predicts the temporal characters of Solid waste, and volatile fatty acid (VFA) in the reactor, and gas production in response to various input loadings and temperatures. The predicted values of VFA and gas production were found to be in good agreement with experimental observations in batch and repeated-input systems. Finally, long-term reactor performance was simulated with respect to the seasonal temperature changes from 5C in winter to 25C in Summer at different food waste input loadings. The simulation results provided us with information concerning the success or failure of a process during long-term operation .

• Coupled systems mechanics
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• 제7권2호
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• pp.233-254
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• 2018

In order to reduce the dependency on fossil fuels, a policy to increase the production capacity of wind turbine is set up. This can be achieved with increasing the dimensions of offshore wind turbine blades. However, this increase in size implies serious problems of stability and durability. Considering the cost of large turbines and financial consequences of their premature failure, it is imperative to carry out numerical simulations over long periods. Here, an energy-conserving time-stepping scheme is proposed in order to ensure the satisfying computation of long-term response. The proposed scheme is implemented for three-dimensional solid based on Biot strain measures, which is used for modeling flexible blades. The simulations are performed at full spatial scale. For reliable design process, the wind loads should be represented as realistically as possible, including the fluid-structure interaction (FSI) dynamic effects on wind turbine blades. However, full-scale 3D FSI simulations for long-term wind loading remain of prohibitive computation cost. Thus, the model to quantify the wind loads proposed here is a simple, but not too simple to be representative for preliminary design studies.

• 한국해양공학회지
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• 제2권1호
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• pp.106-115
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• 1988

반잠수식 시추선의 설계에 있어서 구조의 피로수명을 정확하게 추정하는 것은 매우 중요하며, 또한 어려운 일이다. 본 논문에서는 이미 실용화된 Aker H-3모델에 대하여 Palmgren-Miner 가정에 의하여 시추선의 hot-point인 수평 및 수직 K-brace 멤버에 대하여 피로수명을 로이드 선급의 커브에 따라 계산한 결과 북해의 해성환경 조건에서는 16년 동안 계속 작업을 할 수 있다는 결론을 얻었으나 응력 집중계수 (SCF)를 선정하는데 불확실성으로 인하여 사용하는데 주위를 요한다.

• Nuclear Engineering and Technology
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• 제28권3호
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• pp.257-264
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• 1996

The conventional Equipment Environment Qualification (EEQ) envelope is developed based on the containment responses during the design basis events. The Safety Depressurization System (SDS) design without In-containment Refueling Water Storage Tank (IRWST) adopted in the Ulchin 3&4 challenges the conventional EEQ envelope during long term Feed and Bleed (F&B) operation due to the direct discharge of high mass and energy into the containment. Therefore, it is necessary to confirm that the containment pressure and temperature history during the long term F&B operation does not violate the conventional EEQ envelope. However, this subject has never been quantitatively assessed before. To investigate the success path of long term F&B operation this paper analyzes the thermal hydraulic response of the containment and Reactor Coolant System (RCS) until the completion of depressurization and cooldown of RCS into Shutdown Cooling System (SCS) entry condition. It is found that the SCS entry condition can be reached within 6 hours without violating the EEQ curve by proper operation of SDS valves, High Pressure Safety Injection (HPSI) pumps and active Containment Heat Removal System (CHRS). The suggested strategy not only demonstrates the feasibility of long term F&B operation but also can be utilized in the preparation of Emergency Procedure Guidelines (EPGs)

• Clinical and Experimental Pediatrics
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• 제62권3호
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• pp.108-112
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• 2019

Subacute sclerosing panencephalitis (SSPE) is a rare, progressive, and fatal central nervous system disorder resulting from persistent measles virus infection. Long-term data are scarce, with a maximum follow-up period of 10 years. Interferon-alpha ($IFN-{\alpha}$) is a protein that exerts its antiviral activity via enhancement of cellular immune response and is reported to be an effective drug for the treatment of SSPE. However, there is currently no consensus regarding the optimal duration of $IFN-{\alpha}$ therapy. Here, we present a case report of a patient with SSPE treated with long-term intraventricular $IFN-{\alpha}$ therapy, which facilitated clinical improvement and neurological stabilization without causing serious adverse effects. To the best of our knowledge, this is one of the longest follow-up studies investigating a patient with SSPE receiving intraventricular $IFN-{\alpha}$ treatment. Further studies are necessary to validate the benefits and safety of long-term intraventricular $IFN-{\alpha}$ treatment in patients with SSPE.

• 보건행정학회지
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• 제32권3호
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• pp.258-271
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• 2022

The rapidly aging trend of Korea is a major factor that threatens the sustainability of the long-term care insurance system. Therefore, looking at how Japan and Germany mitigated the financial burden when they managed similar long-term care insurance systems will provide important implications for improving the Korean system in the future. The study was conducted using the literature review method, and the "country" was set as a unit for the case analysis. The three countries selected are Korea, Japan, and Germany. Recently in Korea, the insurance premium rates of all subjects have been rapidly rising, which can exacerbate the issue of intergenerational equity. On the other hand, Japan has responded to the aggravating finances for long-term care insurance due to aging by raising coinsurance for selected groups like the wealthy elderly. Germany is selectively raising the insurance premium rates by additionally increasing the premium rate for childless recipients. A more preventive and quality-oriented care service plan can be promoted by referring to the recent changes in Japan and Germany. In addition, a more effective and selective increase in payment burden in Japan and Germany could be considered in response to a recent equity issue in Korea.

• Journal of Ginseng Research
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• 제37권2호
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• pp.194-200
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• 2013

Korean red ginseng (KRG) is prepared by the process of steaming the roots of Panax ginseng. In this study, the feeding effects of KRG-water extract (KRGE) on ethanol-induced liver damage were elucidated by measuring serum biomarkers in rats. Serum ${\gamma}$-glutamyltranspeptidase (g-GT) activity and the concentration of malondialdehyde (MDA) were significantly increased by short-term and long-term ethanol treatment in rats, whereas the activities of serum glutamate pyruvate transaminase (GPT) and glutamate oxaloacetate transaminase (GOT) did not respond. Pretreatment with KRGE maintained the activity of serum GPT, and the MDA concentration induced by short-term ethanol ingestion remained within the normal range. However, co-feeding of KRGE to rats decreased the concentration of MDA but failed to modulate the serum ${\gamma}$-GT activity induced by long-term ethanol treatment. Our studies suggest that in rats, it appears that KRGE does not sufficiently reverse the physiological response evoked by long-term ethanol ingestion to maintain normal conditions, in view of the serum biomarker ${\gamma}$-GT, regardless of KRGE's favorable antioxidant activity.

• East Asian Economic Review
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• 제18권2호
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• pp.187-212
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• 2014

The purpose of this paper is to examine the equity market crisis contagion in major Asian economic markets. A comparative assessment of Asian markets during the Asian Financial Crisis and Global Financial crisis may clearly identify the changing nature of long term integration of major Asian markets. The selection criteria of specific Asian markets of different peripheries depend particularly on the roles and structure of these markets. The impact of the global financial contagion and the lingering financial linkage in the aftermath of crisis will explain the reaction of the majority of Asian markets to global linkage. While majority of the studies focused on dynamic short term association in European and MENA contagions in the post global financial crisis period; after the global financial crisis, attention paid to long term Asian contagion adds new perspective to hitherto disorganized theories.