• Journal of the Korea Society for Simulation
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• v.14 no.3
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• pp.67-77
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• 2005

Logistics network of the enterprise is defined to determine the optimal node and link considering the production, inventory and transportation based on the demand forecasting. This study consider the optimal logistics network of A painter company which maintain the existing transportation network and plan to relocate its plants and build new distribution centers. For this, we design possible alternative scenarios and install the simulation models for analysis of each scenario. The result of simulation will help the proper logistic network and determining the size of distribution center further.

• The Journal of Korea Robotics Society
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• v.19 no.1
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• pp.79-91
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• 2024

Large warehouses are building automation systems to increase efficiency. However, small warehouses, military bases, and local stores are unable to introduce automated logistics systems due to lack of space and budget, and are handling tasks manually, failing to improve efficiency. To solve this problem, this study designed small loading and unloading equipment that can be mounted on transportation vehicles. The equipment can be controlled remotely and is automatically controlled from the point where pallets loaded with cargo are visible using real-time video from an attached camera. Cargo recognition and control command generation for automatic control are achieved through a newly designed deep learning model. This model is designed to be optimized for loading and unloading equipment and mission environments based on the YOLOv3 structure. The trained model recognized 10 types of palettes with different shapes and colors with an average accuracy of 100% and estimated the state with an accuracy of 99.47%. In addition, control commands were created to insert forks into pallets without failure in 14 scenarios assuming actual loading and unloading situations.

• Journal of the Korea Society of Computer and Information
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• v.26 no.9
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• pp.167-180
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• 2021

Since the mid-1990s, small and medium distribution and retail businesses have been experiencing difficulties due to the active entry of domestic and foreign distribution companies into the distribution industry. Accordingly, in 2003, the government established a small and medium distribution logistics center to secure self-sustainability and strengthen the competitiveness of small and medium distribution and retail businesses. However, in the rapidly changing distribution environment, small and medium distribution logistics centers were becoming increasingly difficult. To strengthen the management capabilities of small and medium distribution logistics centers, 4 primary factors (management operational ability, employee professional competency enhancement, product delivery, customer CS management) and 16 secondary factors were established based on literature research and FGI. We intend to derive the final weight and priority of these factors using AHP, and establish strategies to strengthen the competitiveness of small and medium distribution logistics centers.

• Ocean and Polar Research
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• v.39 no.2
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• pp.149-158
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• 2017

The opsin family of light sensitive proteins family makes up are the universal photoreceptor molecules of all visual systems in the vertebrates including teleosts. They can change their conformation from a resting state to a signaling state upon light absorption, which activates the G-protein coupled receptor, thereby resulting in a signaling cascade that produces physiological responses. However, this species is poorly characterized at molecular level due to little sequence information available in public databases. We have investigated the opsin family of nocturnal cutlass fish using the whole transcriptome sequencing method. The opsin genes were cloned and its expression in the tissues and organs were examined by qPCR. We cloned 6 opsin genes (RRH, Opn4, Rh1, Rh2, VA-opsin, and Opn3) in retina and brain tissue. It contained the seven presumed transmembrane domains that are characteristic of the G-protein-coupled receptor family. However, short wavelength sensitive pigment (SWS) and long wavelength sensitive pigment (LWS) were not detected in this study. The mRNA expression of the 6 photoreceptor genes were detected in retina and peripheral tissue. Our studies will lead to further investigation of the photic entrainment mechanism at molecular and cellular levels in cutlass fish and can be used in comparative studies of other fishes.

• Molecules and Cells
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• v.46 no.6
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• pp.387-398
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• 2023

Microtubule acetylation has been proposed as a marker of highly heterogeneous and aggressive triple-negative breast cancer (TNBC). The novel microtubule acetylation inhibitors GM-90257 and GM-90631 (GM compounds) cause TNBC cancer cell death but the underlying mechanisms are currently unknown. In this study, we demonstrated that GM compounds function as anti-TNBC agents through activation of the JNK/AP-1 pathway. RNA-seq and biochemical analyses of GM compound-treated cells revealed that c-Jun N-terminal kinase (JNK) and members of its downstream signaling pathway are potential targets for GM compounds. Mechanistically, JNK activation by GM compounds induced an increase in c-Jun phosphorylation and c-Fos protein levels, thereby activating the activator protein-1 (AP-1) transcription factor. Notably, direct suppression of JNK with a pharmacological inhibitor alleviated Bcl2 reduction and cell death caused by GM compounds. TNBC cell death and mitotic arrest were induced by GM compounds through AP-1 activation in vitro. These results were reproduced in vivo, validating the significance of microtubule acetylation/JNK/AP-1 axis activation in the anti-cancer activity of GM compounds. Moreover, GM compounds significantly attenuated tumor growth, metastasis, and cancer-related death in mice, demonstrating strong potential as therapeutic agents for TNBC.

• Journal of the Korean Association of Geographic Information Studies
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• v.9 no.2
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• pp.30-41
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• 2006

This paper proposes an e-logistics system supporting efficient vehicle moving trajectory management. Recent advances in wireless communications have given rise to a number of location-based services including logistics vehicle tracking, cellular phone user's location finding, and location-based commerce. Logistics systems typically entail tracking vehicles for purposes of the logistics center knowing the whereabouts of the vehicles and/or consignments. Moreover, storing and managing location trajectory of continuously moving vehicles and consignments is necessary for supporting efficient logistics plan and consignment. The proposed system is able to manage spatial objects in GIS as well as logistic information in the mobile environment. And for the efficiently managing and retrieving of transporting trajectory of logistics, we extend previous moving object indexing method, TB-Tree, to use multi-version framework and evaluate data updating performance. It is able to apply the proposed method to develop mobile contents services based on continuously changing location of moving object in the mobile environment.

• Journal of Korea Port Economic Association
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• v.35 no.3
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• pp.125-150
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• 2019

The Hunchun area is the only development and opening line in Jilin Province and the Changchun-Jilin-Tumen Developmental Plan area, and as a hub area for regional logistics, promoting the logistics competitiveness of the Hunchun area is an important factor in promoting economic development in the Northeast region. The purpose of this study is to derive the factors for activating logistics competitiveness in Hunchun area by applying SWOT analysis and to present them to policy-makers by drawing priority of factors for promoting logistics competitiveness in Hunchun area through AHP survey of Chinese and Korean logistics experts. According to the analysis, the weighting was high in order of opportunity factors and strength factors, and the priority was high in order of factors such as promotion and expansion of One Belt, One Road policies, active support through national policies, construction of international logistics center cities, construction of logistics centers, and supply of bulk cargo. Finally, from a comprehensive perspective, this study presented policy implications such as SO Strategy (Strength-Occupancy Strategy) and ST Strategy (Strength-War Strategy) focusing on the strengths of the Hunchun Region for the strategy of strengthening the logistics competitiveness of the Hunchun area.

• Journal of Navigation and Port Research
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• v.39 no.6
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• pp.553-559
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• 2015

The Korean Ship Supply market scale estimated at 5.7 trillion won in 2014. Much activated and related 400 of companies located in Busan, Ulsan near Busan area. But there have many companies had lower average revenue like a 2 billion won, Also the economic slump of world maritime port industry and low priced ship supply manufacture like as China and Other developing countries, those things made a gloomy situation in domestic industry. Therefore, in this study focused on Ship Supply Common Logistics for activation plan of Ship Supply Industry. And also determine which factor is most important to Ship Supply Common Logistics and analyzed AHP and IP analysis on 16 factors based on literature review. The result, most important factor was cost for Ship Supply Common Logistics.

• Proceedings of the Korean Institute of Navigation and Port Research Conference
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• 2004.11a
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• pp.289-295
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• 2004

The objective of this paper is to analyze the equipment combination of stevedoring system at port container terminal. In general, the productivity of container terminal is evaluated by productivity of container cranes at apron, but there are other equipment such as transport vehicles and yard cranes. Therefore, a method that can estimate the optimal equipment combination of stevedoring system in container terminal is required. We perform various simulation experiment and analyze equipment combination to improve the productivity. From the application of the case study, we demonstrated the savings effect using mean waiting time rates by the equipment combination.

• Journal of the Korea Safety Management & Science
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• v.11 no.4
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• pp.221-228
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• 2009

Electronic Product Code Information Services(EPCIS) is an EPCglobal standard for sharing EPC related information between trading partners. EPCIS provides a new important capability to improve efficiency, security, and visibility in the global supply chain. EPCIS data are classified into two categories, master data (static data) and event data (dynamic data). Master data are static and constant for objects, for example, the name and code of product and the manufacturer, etc. Event data refer to things that happen dynamically with the passing of time, for example, the date of manufacture, the period and the route of circulation, the date of storage in warehouse, etc. There are four kinds of event data which are Object Event data, Aggregation Event data, Quantity Event data, and Transaction Event data. This thesis we propose an event-based data model for EPC Information Service repository in RFID based integrated logistics center. This data model can reduce the data volume and handle well all kinds of entity relationships. From the point of aspect of data quantity, we propose a formula model that can explain how many EPCIS events data are created per one business activity. Using this formula model, we can estimate the size of EPCIS events data of RFID based integrated logistics center for a one day under the assumed scenario.