• Title/Summary/Keyword: Life Cycle of Researchers

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Sublethal Assay of Pesticides and Phenols Using the Nematode Caenorhabditis elegans

  • Hwa, Jung-Ki;Jung, Baek-Su;Young, Choung-Se
    • Proceedings of the Korea Society of Environmental Toocicology Conference
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    • 2003.05a
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    • pp.146-147
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    • 2003
  • The free-living nematode, Caenorhabditis elegans (C. elegans) has been adopted as a multicellular biosensor of biological toxicity for alkylphenol, organotin compounds and heavy metals. To adopt as a biosensor, suitability to assess must be fulfilledthrough several criteria; the organism must be sensitive to the testing toxicants, easy to manage in the laboratory and available throughout the year. C. elegans widely used as a simple multicellular organism in developmental biology studies and satisfies all these criteria, and its culture conditions, developmental staging, anatomy and genetic properties are well defined. In addition, researchers can take advantage of the worm's short life cycle, low cost and little individual variation. Moreover, genomic sequencing of C. elegans has recently been completed. With these aspectsof the organism, C. elegans become a more potent model organism for basic and applied bioassays.

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Study on feasibility analysis for ground source heat pump system using the building foundation (건물기초 이용 지열시스템의 도입 타당성 분석에 관한 연구)

  • Chae, Ho-Byung;Nam, Yujin
    • Proceedings of the Korean Institute of Building Construction Conference
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    • 2013.05a
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    • pp.155-157
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    • 2013
  • Ground source heat pump(GSHP) systems have been attracted as high-efficient energy-saving technology, but the building clients and designers have hesitated to use GSHP systems which is a expensive initial installation and a uncertain economic feasibility. Therefore In order to reduce the initial cost, many researchers have focused on the energy-pile system using the structure of the building as a heat exchanger. Even though many of experimental studies for energy pile system have been conducted, there was not enough data of a quantitative evaluation with the economic analysis and comprehensive analysis for energy-pile. In this study, the feasibility study for the energy pile system with a barrette pile was conducted by the performance analysis and LCC assessment.

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A Study on Data Literacy Competency Building Measures: Focusing on Research Data Management Education (데이터 리터러시 역량 강화 방안에 관한 연구 - 연구데이터 관리 교육을 중심으로 -)

  • Juseop Kim;Suntae Kim
    • Journal of the Korean Society for Library and Information Science
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    • v.57 no.1
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    • pp.115-137
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    • 2023
  • The purpose of this study is to present a guide for the development of research data management education programs for researchers affiliated with domestic universities and research institutions. In order to present the relevant program guide, first, we investigated and analyzed educational programs for overseas research data management. The educational programs studied and analyzed are RDMRose, RDMLA, DataONE, Digital Research Alliance of Canada, NNLM, PARTHENOS and Coursera. In addition, in order to confirm the appropriateness of the education program, it was reviewed through the detailed competency of data literacy researched in Korea. As a result of the review, most of the detailed competencies for data literacy were satisfied. Finally, a program guide for researchers was presented by synthesizing the research data management education programs that were investigated and analyzed. The results of this study will help develop research data management education programs that can systematically support and activate researchers belonging to universities and institutions.

Deduction of Critical Components for establishing the Environmental Load Reduction Guideline in Construction Phase (시공단계 환경부하 저감 가이드라인 구축을 위한 주요 구성항목 도출)

  • Kim, Chang-Won;Kim, Chun-Hak;Cho, Hun-Hee;Kang, Kyung-In
    • Proceedings of the Korean Institute of Building Construction Conference
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    • 2012.11a
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    • pp.127-128
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    • 2012
  • Recently, Construction industry has been trying to reduce environmental loads reflecting the global trend 'Green Growth'. Internal and External countries are provided 'green building certification', 'relevant law/regulations', 'guideline to life cycle', however, construction phase has been overlooked though environmental loads occurred intensively in this phase. Therefore, this study intend to deduct components reflected the guideline in construction phase and assess them quantitatively. The basis data is collected through survey targeting construction managers and related researchers and analyze these data using Analytic Hierarchy Process.

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A theoretical study on Determinants of National Competitive Advantage (산업의 국제경쟁력 결정요인에 관한 이론적 관찰)

  • 이학헌;민성규
    • Journal of the Korean Institute of Navigation
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    • v.19 no.1
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    • pp.49-69
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    • 1995
  • What is the national competitive power\ulcorner What are the determinants of national competitive advantage\ulcorner In order to find these problems, this study was initiated theoretically through the international trade theory and international managerial strategic theory. The flow of studies, in connection with these competitive advantage, come into industries competitive advantage from national competitive advantage. It is understood that the flow of studies is based on the change of paradigm about the international industry environment. Today, the international industry environment has been changed into vigorous situation with the new trade system such as globalization, UR negotiation, WTO system instead of GATT. Among these environments, all enterprises in any industries should try to enhance their benefit, income profits and develop their management strategy, because it is essential for them to keep and make a profit in order to be competitive against all other rivaling enterprises. According to researchers and the ages of history, the concept and determinants of competitive advantage have been dissimiliar as followings. 1) Theory of absolute advantage : Absolute Product Cost. 2) Theory of comparative advantage : Comparative Product Cost. 3) Theory of reciprocal demand : the Reciprocal Demand Structure. 4) Theory of Hechsher-Ohlin : Factor Endowment. 5) Paradox of Leontief : the Quality of Factor Endowment. 6) Theory of technological gap : R & D. 7) Technological gap model : The Technological Gap. 8) Theory of the product life cycle : Product Life Cycle. 9) Christensen's study : Firm's character & manager's character. 10) Monopolistic Advantage Theories : Monopolistic Advantage 11) Electic theory : Ownership, location and internalization specific advantages. 12) Theory of value chain : Cost advantage, Differentiation, Focus. However all these theories have the limit of illustration regarding today's competitive situation, the Porter's theory shows well the determinants of competitive advantage with competitive strategy. Therefore, the analysis of the competitive advantage for maritime industry should be studied by the determinants of competitive advantage of nations

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A Study on the Improvement Plans of the Humanities and Social Sciences Research Data Archives in Korea (국내 인문사회 연구데이터 아카이브의 개선방안에 관한 연구)

  • Shin, Young-Ran;Chung, Yeon-Kyoung
    • Journal of Korean Society of Archives and Records Management
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    • v.12 no.3
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    • pp.93-115
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    • 2012
  • This study aims to propose improvement plans of the Humanities and Social Sciences research data archives in Korea. For this purpose, literature reviews were conducted to prove the importance of the Humanities and Social Sciences research data and establish a theoretical basis for the concept and requirements of data archives. In addition, analysis of the Korean Research Memory (KRM), case surveys for a total of 9 domestic and international archives, and in-depth interviews with a total of 10 researchers in the field of the Humanities and Social Sciences were conducted as well. As for the improvement of the Humanities and Social Sciences research data archives in Korea, establishing a cooperative system between the National Research Foundation of Korea (NRF) and the field of the Humanities and Social Sciences was proposed first for data archives of each project. Secondly, a conceptual model of research data archives was designed in such a way that the archives would perform according to a life cycle of research data in the cooperative system, all based on data curation.

Advancements in Antiviral Drug Development: Comprehensive Insights into Design Strategies and Mechanisms Targeting Key Viral Proteins

  • Wang Hangyu;Li Panpan;Shen Jie;Wang Hongyan;Wei Linmiao;Han Kangning;Shi Yichen;Wang Shuai;Wang Cheng
    • Journal of Microbiology and Biotechnology
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    • v.34 no.7
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    • pp.1376-1384
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    • 2024
  • Viral infectious diseases have always been a threat to human survival and quality of life, impeding the stability and progress of human society. As such, researchers have persistently focused on developing highly efficient, low-toxicity antiviral drugs, whether for acute or chronic infectious diseases. This article presents a comprehensive review of the design concepts behind virus-targeted drugs, examined through the lens of antiviral drug mechanisms. The intention is to provide a reference for the development of new, virus-targeted antiviral drugs and guide their clinical usage.

The Crucial Role of Chloroplast-Related Proteins in Viral Genome Replication and Host Defense against Positive-Sense Single-Stranded RNA Viruses

  • John, Bwalya;Kook-Hyung, Kim
    • The Plant Pathology Journal
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    • v.39 no.1
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    • pp.28-38
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    • 2023
  • Plant viruses are responsible for worldwide production losses of numerous economically important crops. The most common plant RNA viruses are positivesense single-stranded RNA viruses [(+)ss RNA viruses]. These viruses have small genomes that encode a limited number of proteins. The viruses depend on their host's machinery for the replication of their RNA genome, assembly, movement, and attraction to the vectors for dispersal. Recently researchers have reported that chloroplast proteins are crucial for replicating (+)ss plant RNA viruses. Some chloroplast proteins, including translation initiation factor [eIF(iso)4E] and 75 DEAD-box RNA helicase RH8, help viruses fulfill their infection cycle in plants. In contrast, other chloroplast proteins such as PAP2.1, PSaC, and ATPsyn-α play active roles in plant defense against viruses. This is also consistent with the idea that reactive oxygen species, salicylic acid, jasmonic acid, and abscisic acid are produced in chloroplast. However, knowledge of molecular mechanisms and functions underlying these chloroplast host factors during the virus infection is still scarce and remains largely unknown. Our review briefly summarizes the latest knowledge regarding the possible role of chloroplast in plant virus replication, emphasizing chloroplast-related proteins. We have highlighted current advances regarding chloroplast-related proteins' role in replicating plant (+)ss RNA viruses.

An 3-Layer Dimensional Reference Model on the Service Science Research Scope Framework (서비스사이언스의 연구 영역에 관한 3계층 입체 참조 모형)

  • Ahn, Yeon S.;Han, Jae Woo
    • Journal of Service Research and Studies
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    • v.4 no.2
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    • pp.85-95
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    • 2014
  • This research was tried for developing the model on the service science research scope. The suggested model is composed as 3 layer dimensional reference model. The first axis is on the perspective of service life cycle. Another second axis is on the service research characteristics or types. And last axis is also on the service systems. At here, service life cycle is related to service strategy, service development, and service implementation of operation. The service research characteristics or types is related to service basic research, service application research, and service convergence research. Lastly, the service systems is related to the needs analysis, service competence and service resources. This model can be applicable to include the various research topic or theme related on the service sciences. In the future, some enhanced models from researchers or practices from service providers, related on the service science research scope, are expected.

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Life-Cycle Cost Effective Optimal Seismic Retrofit and Maintenance Strategy of Bridge Structures - (I) Development of Lifetime Seismic Reliability Analysis S/W (교량의 생애주기비용 효율적인 최적 내진보강과 유지관리전략 - (I) 생애주기 지진신뢰성해석 프로그램 개발)

  • Lee, Kwang-Min;Choi, Eun-Soo;Cho, Hyo-Nam;An, Hyoung-Jun
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.26 no.6A
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    • pp.965-976
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    • 2006
  • A realistic lifetime seismic-reliability based approach is unavoidable to perform Life-Cycle Cost (LCC)-effective optimum design, maintenance, and retrofitting of structures against seismic risk. So far, though a number of researchers have proposed the LCC-based seismic design and retrofitting methodologies, most researchers have only focused on the methodological point. Accordingly, in most works, they have not been quantitatively considered critical factors such as the effects of seismic retrofit, maintenance, and environmental stressors on lifetime seismic reliability assessment of deteriorating structures. Thus, in this study, a systemic lifetime seismic reliability analysis methodology is proposed and a program HPYER-DRAIN2DX-DS is developed to perform the desired lifetime seismic reliability analysis. To demonstrate the applicability of the program, it is applied to an example bridge with or without seismic retrofit and maintenance strategies. From the numerical investigation, it may be positively stated that HYPER-DRAIN2DX-DS can be utilized as a useful numerical tool for LCC-effective optimum seismic design, maintenance, and retrofitting of bridges.