• Proceedings of the Ginseng society Conference
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• 1988.08a
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• pp.92-98
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• 1988

The present study was performed to find the effects of ginseng and its saponins. which is written in Chung Yao Ta Tsu Tien as anti-amnesia in its chief indication. on experimental amnesia in mice. In the step through test. ginsenoside $Rb_1\;(GRb_1)\;and\;GRg_1$ facilitated the registration of memory and antagonized the electroconvulsive shock (ECS)-induced inhibition of the retention of memory. Moreover. $GRg_1$ antagonized the EtOH-induced inhibition of the retrieval of memory. In the step down test. $GRb_1\;GRb_2\;and\;GRg_1$ antagonized the ECS-induced inhibition of the retention of memory. Moreover. $GRg_1$ antagonized the EtOH-induced inhibition of the retrieval of memory and facilitated the acquisition of short term memory. In the shuttle hox and lever press tests. they have no effects on acquisition and retrieval of memory. except $GRb_1\;GRb_1$ depressed the retrieval of conditioned avoidance response in the shuttle box test. After the end of four tests. the effects of these orally administered drugs on sedative. analgesic. antipyretic and anticonvulsant actions. and on spontaneous and exploratory movements were tested in doses of less than 500mg/kg. but they had none of these effects. Present study may indicate that $GRg_1$ had effects on the retrieval of memory and on the acquisition process of learning response. The recent research on the role of NGF for the survival. regeneration and regulation of brain in adult animals. indicated the importance of NGF on dementia and amnesia. During our research on the specificity of the neurite out growth induced by NGF. we found that the effect of NGF was potentiated by $GRb_1$ in organ cultures of chick embryonic dorsal root ganglia. Then. the effect of $GRb_1$ on neuronal cell survivalin cell culture system was studied. $GRb_1$ potentiated the NGF-mediated increase of neurofilaments in cell cultures of chick embryonic sensory and sympathetic neurons. NGF with $GRb_1$ also showed a tendency to increase the number of surviving neurons of rat embryonic cerebral cortex. NGF increased choline acetyl transferase activity in cell cultures of rat embryonic septum area neurons. but $GRb_1$ did not potentiate NGF activity in cell cultures of rat embryonic septum area neurons. Present study may indicate that $GRb_1$ plays an important role for the survival or regeneration of neurons in the brain.

• Toxicological Research
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• v.18 no.1
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• pp.23-29
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• 2002

Disodium disulphite, the HPV chemical, was assigned to Korea in order to implement OECD SIDS program in 1999. It was produced about 3,200 ton/year in 1998. This report evaluates the toxic potency of disodium disulphite based on the environmental and mammalian effects as well as human exposure. Oral $LD_{50}$ in rats is 1,540 mg/kg b.w. and effects was observed to the stomach, liver and the GI track that was filled with blood. For repeated dose toxicity, the predominant effect was the induction of stomach lesion due to local irritation. The no observed adverse effect lever for local (stomach irritation) was about 217 mg/kg bw/day. There is no evidence that disodium disulphite is genotoxic in vivo. No reproductive or developmental toxicty of disodium disulphite was observed for the period up to 2 yr and over three generation. In humans, urticaria and asthma with itching, edema, rhinitis, and nasal congestion were reported. Disodium disulphite is unlikely to induce respiratory sensitization but may enhance symptom of asthma in sensitive individuals. This chemical would be mainly transported to water compartment when released to environmental compartments since it is highly water soluble (470 g/l at 20). Low K oc (2.447) indicates disodium disulphite is so mobile in soil that it may not stay in the terrestrial compartment. The chemical has been tested in a limited number of aquatic species. hem acute toxicity test to fish, 96 hr-$LC_{50}$ was > 100 mg/1. For algae, 72 hr-$XC_{50}$ was 48.1 mg/1. For daphnid, the acute toxicity value of 48 hr-$EC_{50}$ was 88.76 mg/1, and chronic value of 21day-NOEC was > 10 mg/1. Therefore, PNEC of 0.1 mg/l for the aquatic organism was obtained from the chronic value of daphnid using the assessment factor of 100. Based on these data the disodium disulphite was recommended as low priority for further post-SIDS work in OECD.

• Journal of the Korean Society of Environmental Restoration Technology
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• v.6 no.4
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• pp.62-73
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• 2003

The study was to apply a mat style reed planting method at confluence to improve plants growth conditions by relaxing disturbed topographical base due to water flow and was intended to review the effect to build up a vegetation strip by monitoring process after the construction. First off, We've attempted to construct reed mats on selected sites as confluences of Tan and Gaehwa stream and then examined and analyzed characteristics of soil and vegetation community. As the results of the examination, the soil texture was proven to be a mix of sand and loamy sand and be 6.3 ~ 7.0 soil pH. In addition, it contained 1.0 ~ 4.6% of organic matter, 0.04 ~ 0.22% of T-N and 27.8 ~ 41.2% of water content. For its vegetation structure, the Tan stream confluence was first actually a point bar without plants prior to the construction but 8 kinds of hygrophytes including Persicaria hydropiper and 9 kinds of terrestrial plants such as Potentilla supina, Artemisia annua, and Alopecurus aequalis var. amurensis. On the other hand, the Gaehwa stream confluence contained 6 kinds of hygrophytes such as Bidens frondosa and other 11 kinds of terrestrial plants prior to the construction while it produced 7 kinds of hygrophytes including Ranunculus ternatus as well as Phragmites australis and 9 kinds of terrestrial plants such as Potentilla supina after the construction. For the Phragmites australis, almost of them was weathered away in early days just after planting because of development period passed, but on May, six months later from planting, it was investigated that its length was approximated as 65 ~ 85cm with 75% coverage and that the number of it was 437 ~ 633/$m^2$. The study was shown that reed mats can improve environmental conditions of disturbed topographical base, enabling natural growth of various riparian vegetation including the introduced plant, reed. In the meantime, it was supposedly judged that to recover or build up a vegetarian strip, supplementary materials should be prepared to help produce and grow plants because it is not probable to expect river drift by water flow at confluence and that corrosion, burying or inundation owing to changes of water lever should be considered.

• Fire Science and Engineering
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• v.31 no.3
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• pp.63-72
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• 2017

This study fabricated a low-voltage 10 circuit distribution board based on the KEMC (Korea Electrical Manufacturers Cooperative) 2102-610 standard and performed a characteristics assessment of the developed 10 circuit distribution board to secure product stability. The developed 10 circuit distribution board is designed to have the characteristics of insulation materials, as well as resistance to corrosion ultraviolet radiation and mechanical impact. The developed distribution board is fabricated to have an appropriate protection class of enclosure, electric shock prevention and protection circuits, switchgear and its components, internal electrical circuits and connectors, external conduct terminal, insulation characteristics, temperature rise test, heat resistance, etc. The developed 10 circuit distribution board consists of a single phase circuit and 3-phase circuits. It is possible to measure in real time the leakage current generated from the load distribution line by installing a sensor module at the load side of each of the branched switchgears. In addition, it is possible to increase a circuit according to the use and purpose of the load and to also manage and check the load in real time. Temperature rise tests were performed on the developed 10 circuit distribution board at 18 places including the inlet connection, main circuit and distribution circuit bus bars and bus bar supports, etc. The highest temperature of $65.3^{\circ}C$ was measured at the R-Phase of the connection of the MCCB power supply for the branch circuit bus bar and a temperature rise of $61.6^{\circ}C$ was measured at the T-Phase of the load side. When applying thermal stress to an MCCB for 6 hours at $180^{\circ}C$ using a heat resistant experimental device, it was found that the actuator lever was transformed and moved in the tripped state.

• Archives of design research
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• v.17 no.2
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• pp.351-362
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• 2004

Generally, they respond to a phenomenon, with their any way, which they have looked at in their surroundings, and also put into their action successively and variously according as what it is. A person who has not so much problems in experiential education added to mental and physical ability prefers controlling his manner by himself as seeing, listening and feeling to being cured it by other physical support. Meanwhile, even though there are tools that we use conveniently in everyday life, it is sometimes required that user is able to control his action by himself with a certain interactive function to deal with a accidental situation. For example, in the home, when they were cooking, washing dishes and taking a bath they would not often control their minds on how to act about flowing water through the faucet going back and forth between saving and easygoing. By reasons of those statements, the project has been studied to propose the new conceptual faucet which digital technology is applied to, for recognizing the volume of water flowed through water pipe as counting it with built-in flow meter, and then saving water as controling the water-flow with faucet lever. It means that homemakers can observe the flow rate of water from the faucet placed in front of the sink in kitchen and control it right away for saving water. For studying this project, the kinds and features of the various flow-meters that measure the volume of water-flow were researched and analyzed for taking a reasonable type to the new ideal faucet. According to this analyzing, turbine-flow-meter was selected as appropriate form for the digital display-built-in faucet that would be presented in this project. As the next step, the basic structure was created for developing a new conceptual faucet. Finally two models have been presented through several steps for making the suitable shape to the new style faucet.

• Fire Science and Engineering
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• v.28 no.4
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• pp.21-28
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• 2014

This study obtained the following results by analyzing the standards related to a $1{\phi}$ 2W MCCB and evaluating its heat resistance characteristics. Since KS C 8321 corresponds to IEC 60947-2 standards, most of the related regulations are similar. The NFPA, which presents the user oriented safety regulations, contains no details about tests or inspections, etc., but it does specify in detail the regulations directly related to safety. It can be seen that KS C 8321 classifies in detail the items about tests and inspections. However, IEC 60947-2 and IEEE C37.51 simplified the test and inspection items or omitted some of them. When applying thermal stress to an MCCB for 6 hours at $180^{\circ}C$ using a heat resistant experimental device, it was found that the actuator lever was transformed and moved in the tripped state. In addition, most of the fixing hanger was melted down, losing their function. When applying thermal stress to the MCCB at $90^{\circ}C$, it showed nothing peculiar, but the fixing hanger was partly deformed at $105^{\circ}C$ and $120^{\circ}C$. It was found that the fixing hanger was deformed and the name plate was discolored at $150^{\circ}C$. It can be seen from the analysis of the internals of the MCCB that the trip bar has been melted away and that the up and down operator has moved up. The experiment performed by applying a withstanding voltage of 6 kV for 60 s showed that all items remained intact. In addition, the evaluation of the insulation performance performed by applying DC 500 V using an insulation-resistance tester showed good insulation performance.

• The korean journal of orthodontics
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• v.40 no.4
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• pp.276-287
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• 2010

This case report describes the treatment of a 23-year, 8-month-old female patient with a Class II malocclusion who showed severe bidentoalveolar protrusion and anterior crowding. The treatment plan consisted of extracting all the first premolars, decrowding and en masse retraction of the upper six anterior teeth and lower anteriors. The upper C-plate placed in the midpalatal area combined with lingual sheath fixtures were used as substitutes for posterior anchorage teeth during upper anterior retraction. Preadjusted brackets (0.022-inch) were used for upper anterior decrowding. A 0.9 mm diameter stainless steel lever-arm soldered to the main arch wire facilitated controlled retraction of upper anteriors. The upper and lower dentition was detailed using a tooth positioner during the finishing stage. Correct overbite and overjet were obtained by decrowding and retraction of the upper six anterior teeth into their proper positions. Use of the C-plate and lingual appliances provided ideal anchorage to enhance the improvement in facial balance. The active treatment period was 19 months. The treatment result was stable 13 months after debonding.

• Journal of the Korean Society for Nondestructive Testing
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• v.29 no.2
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• pp.153-161
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• 2009

After several PWSCCs were found in Bugey(France), Ringhals(Sweden), Tihange(Belgium), Oconee, Arkansas, Crystal Fever, Davis-Basse, VC Summer(U.S.A.), Thuruga(Japan), USNRC and PNNL started the research on PWSCC, that is, PINC project. The aim of this project is to fabricate and obtain representative NDE mock-ups with flaws to simulate tight PWSCC cracks, to identify and quantitatively assess NDE methods for accurately detecting, sizing and characterizing tight cracks such as PWSCC, to document the range of locations and crack morphologies associated with PWSCC and observed responses and to incorporate findings from other ongoing PWSCC research programs, as appropriate. By participating in PINC project, Korean morphology technique about PWSCC and NDE technique have improved and become similar lever with other advanced country. Therefore, the evaluation technique of integrity for nickel alloy component has been improved by cooperation with university, research institute and industries.

• Applied Biological Chemistry
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• v.48 no.1
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• pp.103-108
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• 2005

${\alpha}-Amylase$ inhibitor is used to control blood glucose level by inhibiting starch digestion in the small intestine and delaying the absorption of glucose. In this study, we investigated the effect of the ethanol extracts from more than 1400 species of plants against ${\alpha}-amylase$ with the aim of developing a new ${\alpha}-amylase$ inhibitor. In the results, Cornus walteri extracts showed the highest inhibition activity. The inhibitory effect of Cornus walteri extract on the carbohydrate hydrolysis enzymes has different sensitivities against ${\alpha}-amylase$ from salivary and pancreatin and against ${\alpha}-glucosidase$ from yeast and porcine small intestine. In the study of inhibition kinetics of ${\alpha}-amylase$ and ${\alpha}-glucosidase$, Cornus walteri extract showed competitive inhibition against salivary and pancreatin while showing the combination of uncompetitive and noncompetitive inhibition against ${\alpha}-glucosidase$. The Cornus walteri extract was stable at acidic and thermal conditions. As for the blood glucose and body weight levels of Cornus walteri extract, we confirmed anti-hyperglycemic and anti-obesity effects. Also, in the investigation of the mRNA lever, Cornus walteri extract upregulated the level of GLUT4 mRNA in the quadriceps muscle.

• The Journal of Sustainable Design and Educational Environment Research
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• v.14 no.3
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• pp.9-17
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• 2015

In this paper, there are several analysis on G-SEED, Building Energy Efficiency Rating System, Energy Performance Index, Energy Saving Plan about how they are applied by classification and planning standard. The analysis result found out that G-SEED has low select percentage by having difficulties to managing and additional cost when the each class is selected. And also, Building Energy Efficiency Rating System in school is planed in comparably simple design and similar size and also mostly uses high efficient machines, which was in high lever comparing to the system in facilities in other uses. In the case of EPI, there are differences on acquiring grades by each region. Especially, Gyung-gi region has a low grade on architecture part comparing to other parts, which seems to acquire more grades by strengthen insulation performance. By the result from the three standards, many facilities has only formal plan to pass the required standard without considering specialities of each buildings, which has a tendency to have a pattern to have a minimum criteria. However, School has a symbolic building which has a obligation to be the base of the aim for growing green energy buildings and green education for students. Therefore, planning with understanding of specialities of the facility, having various and rational evaluation standards from the planning of the building is necessary.