• Title/Summary/Keyword: Large intestine

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A Herbological study on the plants of Fagales in Korea (한국산(韓國産) 각두목(殼斗目)식물에 관한 본초학적(本草學的) 연구(硏究))

  • Kim, Bong-Kyoo;Jeong, Jong-Kil
    • The Korea Journal of Herbology
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    • v.21 no.2
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    • pp.27-36
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    • 2006
  • Objectives : The plans can be used for medicinal purposes among Fagales in korea and examined their effects and distributions. Methods : The examined herbalogical books and research papers which published at home and abroad. Results : 1. Quercus genus is main kind enough that it has 32 species among 94 species in the Fagales, of which medicinal plants are 8 species. 2. Cortex is the main medicinal parts of medicinal plants in the Fagales which is used in 12 species. 3. According to nature and flavor of medicinal plants in the Fagales, they were classified into balance 23 species, cool 8 and warm 6; rough taste 25, bitter taste 21 and sweet taste 10 in the order. 4. According to meridian propism of medicinal plants in the Fagales, they were classified into large intestine meridian 11 species, spleen meridian 9, lung meridian 8, liver meridian 8 and stomach meridian 6 in the order. 5. According to the properties and principal curative action, they were classified into drugs for antifebrile and detoxicant 16 species, drugs for hemostasis 14, drugs for astriction 11, drugs to relieve cough 8 in the order. 6. It was noticed that every medicinal plant in the Fagales is nontoxic. Conclusion : There were totaled to 9 genera and 94 species in Fagales in Korea and among them medicinal plants are 6 genera, 22 species, some 23% in total.

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A Herbological Study on the Plants of Amygdalaceae in Korea (한국산 앵도과 식물에 관한 본초학적(本草學的) 연구)

  • Jeong, Jong-Gil
    • The Korea Journal of Herbology
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    • v.31 no.1
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    • pp.49-59
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    • 2016
  • Objectives : This objective of this study was to develop the Korean herbology of the plants belonging to Amygdalaceae in Korea. The literatures of the successive generations have been thoroughly investigated to prepare this article.Methods : The 22 herbological books and research papers published at home and abroad were researched into their total catalog, medicinal plants, distribution, medicinal properties, actions etc.Results : There are totaled to 1 genus and 48 species in Amygdalaceae in Korea and among them, medicinal plants were 1 genus, 17 species, some 35 % in total. The Fructus is the main medicinal parts in the Amygdalaceae, which was used in 18 species. According to nature and flavor of medicinal plants in the Amygdalaceae, they were classified into balance 22 species, and warm 11; bitter taste 23, sweet taste 14 and sour taste 13 in the order. According to meridian propism of medicinal plants in the Amygdalaceae, they were classified into large intestine meridian 13 species, lung and liver meridian 11 species respectively. According to the properties and principal curative action, they were classified into drugs for activation of blood 11 species, drugs for detoxification 10 species, drugs for clearing away heat 9 species in the order. The number of toxic species in the Amygdalaceae was examined to be 5 species.Conclusions : Among 48 species in Amygdalaceae in Korea, medicinal plants are 17 species, and are mostly used for drugs for activation of blood, which are 11 species.

Shigella flexneri Inhibits Intestinal Inflammation by Modulation of Host Sphingosine-1-Phosphate in Mice

  • Kim, Young-In;Yang, Jin-Young;Ko, Hyun-Jeong;Kweon, Mi-Na;Chang, Sun-Young
    • IMMUNE NETWORK
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    • v.14 no.2
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    • pp.100-106
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    • 2014
  • Infection with invasive Shigella species results in intestinal inflammation in humans but no symptoms in adult mice. To investigate why adult mice are resistant to invasive shigellae, 6~8-week-old mice were infected orally with S. flexneri 5a. Shigellae successfully colonized the small and large intestines. Mild cell death was seen but no inflammation. The infected bacteria were cleared 24 hours later. Microarray analysis of infected intestinal tissue showed that several genes that are involved with the sphingosine-1-phosphate (S1P) signaling pathway, a lipid mediator which mediates immune responses, were altered significantly. Shigella infection of a human intestinal cell line modulated host S1P-related genes to reduce S1P levels. In addition, co-administration of S1P with shigellae could induce inflammatory responses in the gut. Here we propose that Shigella species have evasion mechanisms that dampen host inflammatory responses by lowering host S1P levels in the gut of adult mice.

Evaluation of Robust Classifier Algorithm for Tissue Classification under Various Noise Levels

  • Youn, Su Hyun;Shin, Ki Young;Choi, Ahnryul;Mun, Joung Hwan
    • ETRI Journal
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    • v.39 no.1
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    • pp.87-96
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    • 2017
  • Ultrasonic surgical devices are routinely used for surgical procedures. The incision and coagulation of tissue generate a temperature of $40^{\circ}C-150^{\circ}C$ and depend on the controllable output power level of the surgical device. Recently, research on the classification of grasped tissues to automatically control the power level was published. However, this research did not consider the specific characteristics of the surgical device, tissue denaturalization, and so on. Therefore, this research proposes a robust algorithm that simulates noise to resemble real situations and classifies tissue using conventional classifier algorithms. In this research, the bioimpedance spectrum for six tissues (liver, large intestine, kidney, lung, muscle, and fat) is measured, and five classifier algorithms are used. A signal-to-noise ratio of additive white Gaussian noise diversifies the testing sets, and as a result, each classifier's performance exhibits a difference. The k-nearest neighbors algorithm shows the highest classification rate of 92.09% (p < 0.01) and a standard deviation of 1.92%, which confirms high reproducibility.

Feasibility of Computed Tomography Colonography as a Diagnostic Procedure in Colon Cancer Screening in India

  • Manjunath, Kanabagatte Nanjundappa;Gopalakrishna, Prabhu Karkala;Siddalingaswamy, Puttappa Chandrappa
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.13
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    • pp.5111-5116
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    • 2014
  • Computed Tomography Colonography (CTC) is a medical imaging technology used in identifying polyps and colon cancer masses in the large intestine. The technique has evolved a great deal since its invention and has become a routine diagnostic procedure in Western countries due to its non invasiveness and ease of use. The objective of our study was to explore the possibility of CTC application in Indian hospitals. This paper gives an overview of the procedure and its commercial viability. The explanation begins with the domain aspects from gastroenterologist perspective, the new way of thinking in polyp classification, the technical components of CTC procedure, and how engineering solutions have helped clinicians in solving the complexities involved in colon diagnosis. The colon cancer statistics in India and the results of single institution study we carried out with retrospective data is explained. By considering the increasing number of patients developing colon malignancies, the practicality of CTC in Indian hospitals is discussed. This paper does not reveal any technical aspects (algorithms) of engineering solutions implemented in CTC.

A Experimental Study on the effects of DAEWHAJUNGEUM (대화중음(大和中飮)의 효능(效能)에 관(關)한 실험적(實驗的) 연구(硏究))

  • Yang, Su-Mi;Ryu, Bong-Ha;Park, Dong-Won;Ryu, Ki-Won
    • The Journal of Korean Medicine
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    • v.18 no.2
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    • pp.82-96
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    • 1997
  • In order to investigate the effect of Daewhajungeum on the isolated organs, gastrointestinal tract and C.N.S., some kinds of experiments using mice and rats were done. The results were as follows; 1. Daewhajungeum showed the inhibitory effect on the smooth muscle contraction of the isolated ileum and colon induced by acethylchorine chloride and barium chloride in mice. 2. Daewhajungeum showed inhibitory effect on the contraction of the fundus-strip induced by acethylchorine chloride and barium chloride in rats. 3. The preventive effect on pyloric ulcer, indomethacin induced ulcer and ethanol-HCl induced ulcer of mice was recognized. 4. The effect on the acidity of gastric juice was suppressed, but the effect on the pepsin output was not recognized. 5. The transport ability of small and large intestine was significantly decressed. 6. The analgesic effect and the sedative effect were recognized so that the effect of the C.N.S was suggested.

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Effects of High Amylose Starch on Gut Functions in Rats (고아밀로오스전분의 섭취가 흰쥐의 장기능에 미치는 영향)

  • 설소미;방명희;정미경;김우경
    • Journal of Nutrition and Health
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    • v.36 no.2
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    • pp.109-116
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    • 2003
  • This study investigated the effects of high amylose starch (HAS) consumption on gut functions in male Sprague-Dawley rats. Experimental animals were fed an diet containing HAS for 4 weeks (0, 125, 250, 500 g/kg diet). Stool weights, transit time, the pH of cecum, Bifidobacterium growth, short chain fatty acid production, and prostaglandin E$_2$production in colon mucus were measured. HAS intake did not affect body weight gain or food efficiency ratio during experimental period. There were no significant differences in kidney weight, epididymal fat pad weights or spleen weights, but the weights of the liver and thymus were significantly lower in the HAS100 group. The length of the large intestine, the weights of the cecum wall and cecum contents, and stool weights significantly increased through HAS intake. But transit time was not affected by the experimental diet. Although Bifidobacterium growth in the cecum increased through the HAS intake dose dependently, there were significant differences in the HAS50 and HAS100 groups. HAS intake increased the production of short chain fatty acid in the cecum contents. In particular, acetate and butyrate concentrations grew significantly. And the production of prostaglandin E$_2$in the colon mucus significantly decreased through HAS intake. These results demonstrate that high amylose starch intake significantly improves gut function.

Recent Clinical Research on Effect of Acupuncture on Sore Throat (인후통의 침치료에 대한 국외 임상 연구 동향)

  • Han, Ye ji;Lee, Sun Haeng;Lee, Jin Yong
    • The Journal of Pediatrics of Korean Medicine
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    • v.30 no.2
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    • pp.47-55
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    • 2016
  • Objectives The purpose of this study is to investigate recent clinical studies on the effect of acupuncture on sore throat. Methods Based on the PubMed search with the key search terms of 'sore throat, acupuncture', dated from 1992 to 2015, 7 controlled trials and 8 case series was found, and were analyzed for this study. Results 1. The most commonly used acupoints were Quchi (LI11), and Hegu (LI4). 2. The most commonly used meridians were The Lung Meridian of Hand-Taiyin and The Large Intestine Meridian of Hand-Yangming. 3. Acupuncture treatment was effective for both acute and chronic sore throat. 4. More clinical studies are needed to prove the effectiveness of the acupuncture on sore throat. To be more objective on the study results, we can measure temperature drops on or amount of analgesic consumption for sore throat after acupuncture treatment.

Protein-losing Enteropathy Induced by 4 Different Etiologies (4가지 다른 병인들에 의해 유발된 단백소실성 장병증 증례)

  • Cho, Kyu-Woan;Moon, Jong-Hyun;Lee, Hee-Chun;Kwon, Do-Hyung;Kang, Byeong-Teck;Sur, Jung-Hyang;Jung, Dong-In
    • Journal of Veterinary Clinics
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    • v.29 no.1
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    • pp.93-97
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    • 2012
  • Four dogs (case 1; 2-year-old spayed female Schnauzer, case 2; 3-year-old spayed female Cocker Spaniel, case 3; 9-year-old castrated male Yorkshire Terrier, and case 4; 9-year-old intact female Shih-tzu) were referred to us with gastrointestinal signs such as diarrhea, vomiting, and anorexia. Results of blood analysis revealed hypoproteinemia and hypoalbuminemia in all dogs. Case 4 showed large circular mass which is connected with small intestine on abdominal ultrasonography and other 3 cases showed no remarkable findings on abdominal radiography and ultrasonography. We performed enterectomy in case 4 and gastrointestinal endoscopic examination with biopsy in other 3 patients. Finally, 4 patients diagnosed to protein losing enteropathy with 4 different etiologies.

Observations of lymphoid polyps on the gastrointestinal tract (위장벽(胃腸壁)에 발생(發生)한 Lymphoid Polyps의 병리학적관찰(病理學的觀察))

  • Kwak, Soo-dong
    • Korean Journal of Veterinary Research
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    • v.24 no.2
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    • pp.195-199
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    • 1984
  • The present observations were focussed mainly on the macroscopic and histopathological observation to polyps encountered on the stomach of 4-month-old pig, small intestine of 3-month-old pig and cecum of 9-month-old dog. The results were summarized as follows; 1. The polyps were gray or pink hemispherical shapes attached by the broad base to the gastrointestinal walls and were 3 to 8 mm in diameter and diffuse appearance. The surfaces of polyps were flat or indented and were ulcerated in some large polyps. 2. In histopathological findings, the polyps were nodules composed of lymphoid follicles, which were characterized by the differentiation and proliferation of the lymphoid cells in the lamina propria or submucosa of the gastrointestinal tract. The lymphoid nodules have the thin septa and thick capsules of the connective tissues, also comprised more numerous and larger sinus-like-blood vessels and more diffuse lymphoid cells in the peripheral zones than those in the central zones of nodules. In addition, the external surface of the polyps bulged toward the intestinal lumen were covered with the abnormal epithelium, or the degenerative and necrotic lymphocyte aggregates. 3. These polyps were considered as lymphoid polyps caused by the hyperplasia of the lymhoid follicles.

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