• Title/Summary/Keyword: LAM-B

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A New Flavonol Glycoside from the Leaves of Boscia senegalensis

  • Morgan, Abubaker M.A.;Kim, Jang Hoon;Kim, Sang Kyum;Lim, Chi-Hwan;Kim, Young Ho
    • Bulletin of the Korean Chemical Society
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    • v.35 no.12
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    • pp.3447-3452
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    • 2014
  • Detailed chemical investigation of Boscia senegalensis (Per) Lam. ex Poir. led to the isolation of one new flavonol glycoside, rhamnocitrin-3-O-${\beta}$-$\small{D}$-(6"-O-E-feruloyl)-glucopyranoside named bosenegaloside A (1), with seven known compounds, rhamnocitrin-3-O-${\beta}$-$\small{D}$-(6"-O-E-p-coumaroyl)-glucopyranoside (2), rhamnocitrin-3-O-${\beta}$-$\small{D}$-glucopyranoside (3), 3,4,5-trimethoxyphenol-${\beta}$-$\small{D}$-glucopyrinoside (4), lasianthionoside A (5), 3,7-dimethyl-1-octene-3,6,7-triol-6-O-${\beta}$-$\small{D}$-glucopyranoside (6), syringin (7), and austroside B (8). The chemical structures of these compounds were elucidated from spectroscopic data and by comparison of these data with previously published results. The inhibitory activity of the isolated compounds on soluble epoxide hydrolase (sEH) was assessed. Compounds 1-3 potently inhibited sEH activity with $IC_{50}$ values of $12.8{\pm}0.5$, $18.4{\pm}0.2$, and $11.3{\pm}0.9{\mu}M$, respectively.

In silico Analysis of Natural Compounds as Modulators of Type I Collagen

  • Narayanaswamy, Radhakrishnan;Wai, Lam Kok;Esa, Norhaizan Mohd;Ismail, Intan Safinar
    • Journal of Integrative Natural Science
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    • v.9 no.3
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    • pp.166-170
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    • 2016
  • Collagen plays a vital role in the maintenance of structure and function of a human body. It has been widely applied in various fields including biomedical, cosmeceutical, food, pharmaceutical and tissue engineering. In the present study, the docking behaviour of type I collagen with 15 different ligands namely hydroxymethylfurfural, methylglyoxal, methylsyringate, O-methoxyacetophenone, 3-phenyllactic acid, 4-hydroxybenzoic acid, kojic acid, lumichrome, galangin, artoindonesianin F, caffeic acid, 4-coumaric acid, origanol A, thymoquinone and quercetin was evaluated along with their putative binding sites using Discovery Studio Version 3.1. Docking studies and binding free energy calculations revealed that origanol A has maximum interaction energy (-40.48 kcal/mol) and quercetin with the least interaction energy (-15.44 kcal/mol) as compared to the other investigated ligands. Three ligands which are galangin, methylsyringate and origanol A were shown to interact with Asp21 amino acid residue of chain B (type I collagen). Therefore, it is strongly suggested that the outcomes from the present study might provide new insight in understanding these 15 ligands as potential type I collagen modulators for the prevention of collagen associate disorders.

A Semi-Soft Handoff Mechanism with Zero Frame Loss in Wireless LAM Networks (무선 LAN 환경에서 프레임 손실 없는 Semi-Soft 핸드오프 방안)

  • 김병호;민상원
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.28 no.12B
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    • pp.1135-1144
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    • 2003
  • In this paper, we proposed a semi-soft handoff mechanism to provide link mobility in IEEE 802.11 wireless LAN environment. Buffers and routing tables in APs and portals are provided in order to reroute frames, which have not been received during handoff time and have been buffered in an old AP, to a new AP after handoff is performed. For the re -routing operation, the MAC routing table should be updated by exchanging information of a mobile terminal between neighbor APs. With our proposed scheme. a wireless LAN node can perform semi soft handoff while changing its attached AP and provide mobile IP and/or real time service like voice over IP. Also, we have done simulation for evaluation of the performance of the proposed scheme. We show that our semi soft handoff mechanism can be applied for real-time service with no frame loss in mobile environment.

The Effects of Plasma Treatments on the Surface Energy of the Polycarbonates and on the Adhesion Strength of the Cu Film/Polycarbonate Interface (플라즈마 표면처리에 의한 폴리카보네이트의 표면에너지 및 구리박막과의 접착력 변화에 관한 연구)

  • Cho Byeong-Hoon;Lee Won-Jong;Park Young-Ho
    • Korean Journal of Materials Research
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    • v.15 no.11
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    • pp.745-750
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    • 2005
  • Polycarbonates are widely used as housing materials of electronic handsets. Since the polycarbonate is electrically insulating, there should be a conducting layer on the polycarbonate for EMI shielding. In this study, we sputter deposited Cu films on the polycarbonate substrates for EMI shielding. Plasma treatments of polycarbonates were used to increase the adhesion strength of the Cu film/polycarbonate interface. The surface energy of the polycarbonate was greatly increased from $30mJ/m^2 \;to\; 65mJ/m^2$ by a 200 W $O_2$ plasma treatment for 10s. It is thought that this is because of the ion bombardment. The adhesion strength of the sputter deposited Cu film to the polycarbonate was quantitatively measured by a 4 point bending tester. A moderate plasma surface treatment of the polycarbonate increased the Cu film/polycarbonate adhesion strength by $30\%$. The EMI shielding efficiency of the sputter deposited $10{\mu}m$ Cu lam on the polycarbonate showed 90dB in the range of 100MHz to 1000MHz.

Porcine epidemic diarrhea viruses from Vietnam: isolation, characterization, and neutralizing activity

  • Van Tan Do;Quang Lam Truong;Hoai Thu Dao;Thi Lan Nguyen;Minna Shin;Kyeong Ryeol Shin;Tae-Wook Hahn
    • Korean Journal of Veterinary Research
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    • v.63 no.2
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    • pp.18.1-18.8
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    • 2023
  • Porcine epidemic diarrhea (PED) is characterized by acute enteritis, watery diarrhea, weight loss, dehydration, and death, with high mortality in neonatal piglets. In this study, 3 virus isolates collected in Vietnam between 2016 and 2017 were propagated successfully in Vero cells at high virus titers. Sequence analysis of the full-length spike (S) gene showed that all 3 isolates belong to genogroup 2b, which is closely related to other prevalent Asian strains. A comparison of the amino acid sequence revealed a 98.19% to 99.13% homology with the Vietnam isolates circulating during 2013-2015, suggesting that field PED viruses (PEDVs) are evolving continuously. Experiments in animals showed that the antisera from guinea pigs immunized with the vaccine strain resulted in higher levels (5 log2) of neutralizing antibodies against the homologous strain and a relatively moderate level of neutralizing antibodies against the field isolates. This finding would be helpful in selecting a PEDV strain for vaccine development.

Quality Characteristics of Bread Manufactured with Sweetpotato Leaf Powder (고구마(Ipomoea batatas (L.) Lam) 잎 분말을 첨가한 식빵의 품질 특성)

  • Han, Seon-Kyeong;Kang, Chon-Sik;Kim, Jae-Myeong;Yang, Jung-Wook;Lee, Hyeong-Un;Hwang, Um-Ji;Song, Yeon-Sang;Lee, Joon-Seol;Nam, Sang-Sik;Lee, Kyeong-Bo
    • The Korean Journal of Food And Nutrition
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    • v.28 no.4
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    • pp.571-578
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    • 2015
  • This study was carried out to investigate the quality characteristics of bread containing sweetpotato (Ipomoea batatas (L.) Lam) leaf powder (0, 2, 3, 5, and 7% of the total flour). We found that the addition of sweetpotato leaf powder decreased the pH of the dough, whereas the total titratable acidity increased and the specific volume and baking loss of bread were decreased. However, the moisture content of the bread did not show any significant differences. The L and a values of the bread inner crumb were decreased by the addition of sweetpotato leaf powder, however, the b value was increased. The 2,2-diphenyl-1-picrylhydrazyl-radical scavenging activity, total polyphenol, lutein and ${\beta}-carotene$ contents were increased significantly by the addition of sweetpotato leaf powder. The taste, color, flavor, chewiness and overall acceptability of bread containing 2~3% sweetpotato leaf powder were better than those of the controls. We found that the sample group with 2~3% sweetpotato leaf powder is the optimum content for making bread.

Comparison of diagnostic methods for detection of Brucella species in dog blood samples (개 혈액 재료에서의 Brucella 검출을 위한 진단방법의 비교)

  • Kwon, Soon-Oh;Lam, Truong Quang;Her, Moon;Ahn, Dong-Chun;Park, Sang-Hee;Park, Mi-Yeoun;Lee, Young-Ju;Hahn, Tae-Wook
    • Korean Journal of Veterinary Service
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    • v.32 no.4
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    • pp.335-341
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    • 2009
  • Canine brucellosis produce abortions and infertility in dogs and is currently diagnosed by serological methods such as rapid slide agglutination test with 2-mercaptoethanol (2-ME RSAT) and immunochromatographic assay (ICA). Bacterial isolation is considered gold standard for Brucella diagnosis and the polymerase chain reaction (PCR) is an alternative method to bacterial isolation. A total of 36 whole blood samples were collected from dogs reared in area of Chuncheon and were subjected to serology (2-ME RSAT and ICA for B. canis, Rose Bengal test and C-ELISA for B. abortus), blood culture and 3 types of PCRs (BSCP31, 16s rRNA, and OMP-2). All blood samples were negative by serology and blood cultures. The BCSP31 and the OMP-2 PCR detected 5 samples were positive whereas the 16S rRNA PCR detected all samples were negative as serological methods and blood culture did. From the results observed in the present study, we conclude that 16S rRNA PCR could be used for direct PCR for canine blood samples.

Performance analysis of campus wireless LAN in outdoor environment (실외환경에서 캠퍼스무선랜의 성능분석)

  • Kang Min-soo;Kim Myeong-hwan;Park Yeoun-sik
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.9 no.4
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    • pp.753-757
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    • 2005
  • Wireless LAN was developed by alternative of LAN and because establishment was easy, have used into special field and special expenditure. Recently, Standard and a technology developed by leaps and bounds. Present is used into purpose of the Building to Building or wide connection etc. and relay of the high speed Internet and usage of picture communication that require multimedia band width. Specially, campus wireless LAM is thought that must secure radius $100\;\~\;200\;m$ dimension at the minimum 10Mbps speed as Internet transit trunk. But, there is difference as degressive here. In this paper, wireless LAN measured for effectiveness proof as Internet transit trunk in actuality utilization environment. Proved that should compose IEEE802.11b as AP more than minimum 3 when compose network to base as measuring result. Hereafter, there is the purpose that achieve performance evaluation of wireless UM in marine environment.

Isolation and characterization of Brucella abortus isolates from wildlife species in South Korea

  • Truong, Quang Lam;Kim, Kiju;Kim, Jong-Taek;Her, Moon;Jung, Suk-Chan;Hahn, Tae-Wook
    • Korean Journal of Veterinary Research
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    • v.56 no.3
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    • pp.147-153
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    • 2016
  • A total of 782 blood and 465 tissue samples from 1,039 wild animals and 127 dairy goats were collected from January 2011 to December 2013 in 10 provinces of South Korea and tested for the presence of brucellosis. The Rose Bengal test revealed that 8.0% (52/650) of the serum samples were seropositive, while 4.2% (33/782) of the serum samples were positive for Brucella antibodies by competitive enzyme-linked immunosorbent assay. Of the 650 sera examined, only 16 (2.5%) were positive by both serological tests. Direct polymerase chain reaction (PCR) assay using B4/B5 primers for Brucella abortus (BCSP31) revealed the prevalence of Brucella to be 26.5% (129/487) in blood samples and 21% (98/465) in tissue samples while, 16S rRNA PCR detected Brucella DNA in 6.8% (33/487) and 2.6% (12/465) in blood and tissue samples, respectively. Of PCR-positive samples, only 6.2% (30/487) of blood samples and 2.4% (11/465) of tissue samples were found to be positive by both BCSP31 and 16S rRNA PCRs. However, Brucella strains were isolated by blood culture from only two out of 487 blood samples (0.4%). This characterization and identification of pathogenic Brucella isolates is the first to clearly indicate that the organisms were Brucella abortus biovar 1.

Management Plan and Vascular Plants of the Hwarang District in Gyeongju National Park (경주국립공원 화랑지구의 관속식물상과 관리방안)

  • You, Ju-Han;Mun, Sung-Ju;Lee, Woo-Sung
    • Journal of the Korean Society of Environmental Restoration Technology
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    • v.14 no.5
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    • pp.17-35
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    • 2011
  • The purpose of this study is to offer the raw data for management and conservation of national park by systematic and objective surveying and analysing the flora distributed in the Hwarang district, Gyeongju national park. The results are as follows. The vascular plants in this site were summarized as 396 taxa: 95 families, 272 genera, 351 species, 2 subspecies, 38 varieties and 5 forma. The rare plants designated by Korea Forest Service were 5 taxa: Exochorda serratifolia S.Moore, Potentilla discolor Bunge, Prunus yedoensis Matsum, Lysimachia coreana Nakai and Inula salicina var. asiatica Kitam.. The korean endemic plants were 6 taxa: Populus tomentiglandulosa T.B.Lee, Clematis trichotoma Nakai, Lespedeza maritima Nakai, Lysimachia coreana Nakai, Forsythia koreana (Rehder) Nakai and Weigela subsessilis (Nakai) L.H.Bailey. The specific plants by floristic region were 30 taxa: Asplenium sarelii Hk., Salix chaenomeloides Kimura, Lysimachia barystachys Bunge, Achillea alpina L., Celtis aurantiaca Nakai, Vitex negundo var. incisa (Lam.) C.B.Clarke and so forth. The plants with approval for delivering oversea were 6 taxa: Clematis trichotoma Nakai, Exochorda serratifolia S.Moore, Glycine soja Siebold & Zucc., Lespedeza maritima Nakai, Lysimachia coreana Nakai and Weigela subsessilis (Nakai) L.H.Bailey. The naturalized plants were 49 taxa: Bilderdykia dumetora (L.) Holub, Descurainia pinnata Britton, Oxalis corymbosa DC., Bidens frondosa L., Panicum dichotomiflorum Michx. and so forth. The invasive alien plants were 2 taxa: Ambrosia artemisiifolia L. and Aster pilosus Willd. In future, if we will survey the flora of whole Gyeongju national park, we will offer the help to establishing the conservation plan of ecosystem in Gyeongju national park.