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A Study on Cytokines in the Mongolia Mare's Milk (몽고 마유에 함유된 사이토카인에 관한 연구)

  • 신무호;남명수;배형철;아말사나룹산돌주;알탄체체그미시그;윤도영
    • Food Science of Animal Resources
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    • v.23 no.1
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    • pp.75-79
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    • 2003
  • This study was carried out to detect the pro-inflammatory cytokines(IL-1, IL-6, TNF-a, IL-18) and IL-1 receptor accessory in mongolia mare's milk by western blotting. IL-1 and TNF-a were detected in 4 samples of mare's milk Proteins of 6 kD and 7 kD were bound to specific antibody against hIL-18. But, IL-l and TNF-a were not detectable in Difco skim milk IL-6 like factor of 60 kD was detected in both Difco skim milk and mare's milk. Also, IL-1 receptor accessory of 55 kD was detected in the mongolia mare's milk.

Herbicidal Activity of Naturally Developed d-Limonene against Sicyos angulatus L. under the Greenhouse and Open Field Condition (온실 및 노지조건에서 천연물질 d-Limonene의 가시박에 대한 살초활성)

  • Kang, Chung-Kil;Oh, Young-Joo;Lee, Sang-Beom;Lee, Byung-Mo;Nam, Hong-Shik;Lee, Yong-Ki;Jee, Hyeong-Jin;Hong, Moo-Ki;Koo, Suk-Jin
    • Korean Journal of Weed Science
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    • v.31 no.4
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    • pp.368-374
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    • 2011
  • This experiment was conducted to Investigate the herbicidal activity of naturally developed d-Limonene on the control of Sicyos angulatus L. which is destructive to biodiversity and ecosystem under greenhouse and open field condition. Among the tested concentrations, most efficacy of early foliar application(leaf stage with 1.5 and 3) of d-Limonene was found in $70mg\;mL^{-1}$, followed by $35mg\;mL^{-1}$, $17.5mg\;mL^{-1}$ in that order under greenhouse condition. The higher the d-Limonene concentration, the better the effect in greenhouse condition. In leaf stage with 2, 3 and 5 under open field condition, the higher the d-Limonene concentrations, the higher the weeding effect. The remarkable effect was, particularly, found in d-Limonene with $70mg\;mL^{-1}$ while little was found in the plants with d-Limonene with $35mg\;mL^{-1}$. In the case of 15 leaf stage of S. angulatus L. treated with d-Limonene under outside treatment effect was low. The treatment effect of d-Limonene under open field compared with greenhouse condition was more significant. It can be recommended that d-Limonene with $70mg\;mL^{-1}$ could control S. angulatus L. by 5 leaf stage.

Plant Regeneration from Cambium Callus of Ailanthus altissima Swingle (가중나무의 형성층(形成層) Callus에서 식물체(植物體) 재분화(再分化))

  • Lee, Sang Goo;Park, Young Goo
    • Journal of Korean Society of Forest Science
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    • v.78 no.4
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    • pp.412-418
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    • 1989
  • The stem segments of Ailanthus altissima were cultured on the Murashige & Skoog's medium(1962) supplemented with 0.1 mg/l BAP and 1.0 mg/l 2, 4-D for callus induction and proliferation, Shoot primordia were observed as greenish regions on the surface of yellow-brown calli about 8 weeks after culture. Shoot primordia were selected and transferred to the MS media containing various combination of BAP and 2, 4-D. Among these combinations the shoot primordia cell clusters on the medium added to 0.5mg/l BAP and 0.01mg/l 2, 4-D exhibited the highest number of shoot formation. These shoots were successfully transferred on the solid MS medium with no growth regulators for the rootings.

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A Study for risk management on Documentary Collection(D/P, D/A) Payment (추심결제(D/P, D/A)방식에서의 위험관리에 관한 연구)

  • Kwak, Su-Young
    • International Commerce and Information Review
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    • v.10 no.2
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    • pp.283-304
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    • 2008
  • According to globalization and localization of world economics international trade payment method was also changed. A traditional payment was Letter of Credit basis, however it is being increased to various methods such as remittance, documentary collection(D/P, D/A) and open account. In order to acquire a secure export payment, exporters prefer to L/C basis which is guaranteed by a reliable bank. However, the L/C should bear a security so that importers would rather documentary collection than L/C. The reasons for the preference of collection payment rather than L/C are a low commission cost, the conversion of buyer's market from seller's market due to severe competition in the world market, transaction increase between main office and branches and a right to control the goods until executing the payment by exporters. Besides of them, collection payment can handle safer and faster than open account basis. However, the collection payment has a risk which it isn't guaranteed by bank for the payment so that I would suggest countermeasures to minimize the payment risk utilizing the collection basis as follows; using export credit insurance system, a large domestic credit report provider such as D&B for absolutely fresh and new information, a collection proxy service for overseas deferred credit and suggestion specifying to order B/L not straight one on consignee in order to transfer the right of ownership with endorsement without problem.

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Comparative Study of Morphology on Male Sex Comb Variation of the Drosophila Species (Drosophila 수종의 성즐변이에 관한 형태적 비교 연구)

  • Choi, Yung-Hyun;Kwon, Yong-Won;Yoo, Mi-Ae;Lee, Won-Ho
    • Korean journal of applied entomology
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    • v.33 no.4
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    • pp.216-224
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    • 1994
  • Sex combs which lack in females are characteristic of some members of the subgenus Sophophora When present, they can be van/ from a single blistle to very extensive structures, but the meianogaster subgroup of the subgenus Sophophora have only on the f~rst tarsal segments of the fore legs. D mauritiona among the melanogaster compler of the melar~ogaster subgroup have significantly more sex comb teeth (mean 12.75) than other specie& and the yakubo complex (range of the mean 6.84-758) have less than the melanogaster complex (range of the mean 835-12.75). In sex comb tooth number of interspecd~ch ybrids among the melonogoster complex, there appeared difference u;ith parental species Thus, analysis of male sex comb tooth in FI hybrid could not exhibit the direction of hereditan/ nature. On the other hand, D auraria (the montium subgroup), D suzuki (the suzuki subgroup) and D, lutecens (the takohashii subgroup) of the melanogaster species have two sex combs on the first and second tarsal segments, and the mean number were different according to the species.

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1.6 Tb/s (160x10 Gb/s) WDM Transmission over 2,000 km of Single Mode Fiber (1.6 Tb/s (160x10 Gb/s) WDM 신호의 단일 모드 광섬유 2,000 km 전송)

  • 한진수;장순혁;이현재
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.29 no.7A
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    • pp.712-718
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    • 2004
  • We report 1.6 Tb/s (160${\times}$10 Gb/s) WDM transmission over 2,000 km of single mode fiber using distributed hybrid(distributed Raman amplifier+Erbium-doped fiber amplifier) optical amplifiers. After transmission over 2,000 km of single mode fiber, average optical signal to noise ratios of C/L-band were 20.5 dB, 21.9 dB, respectively. The minimum Q-factors of each band were 14.65 dB (BER=5.8e-8) in C-band, 13.75 dB (BER=5.0e-7) in L-band without forward error correction. We performed 1.6 Tb/s error-free transmission over 2,000 km of single mode fiber using Reed-Solomon (255, 239) forward error correction code.

Geological Structure of Precambrian to Paleozoic metasedimentary rocks in the Janggunbong area, Korea-Crustal evolution and environmental geology of the central part of the North Sobaegsan massif, Korea- (장군봉지역 선캠브리아대-고생대 변성퇴적암류의 지질구조-북부 소백산육괴의 중앙부지역의 지각진화와 환경지질)

  • 강지훈;김형식;오세봉
    • The Journal of the Petrological Society of Korea
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    • v.6 no.3
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    • pp.224-259
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    • 1997
  • The Janggunbong area(this study area) at the central-south part in the North Sobaegsan Massif, Korea, consists mainly of Precambrian(Wonnam and Yulri Formations)-Paleozoic [Joseon Supergroupuangsan Quarzite, Dueumri Formation and Janggun Limestone) and Pyeongan Group (Jaesan and Dongsugok Formations)l metasedimentary rocks and Mesozoic granitoid(Chunyang granite). This study is to interpret geological structure of the North Sobaegsan Massif in the Janggunbong area by analysing rock-structure and microstructure of the constituent rocks. It indicates that its geological structure was formed at least by four phases of deformation after the formation of gneissosity(S0) in the Wonnam Formation and bedding plane(S0) in the Paleozoic metasedimentary rocks. The first phase deformation(D1) formed tight isoclinal fold(F1). Its axial plane(S1) strikes east-west and steeply dips north. Its axis(L1) subhorizontally plunges east-west. The second phase deformation(D2), which was related to ductile shear deformation, formed stretching lineation(L2) and shear foliation(S2). The sense of the shear movement indicates dextral strike-slip shearing(topto-the east shearing). The third phase deformation(D3) formed open inclined fold(F3). Its axial plane(S3) strikes east-west and moderately or gently dips north. Its axis(L3) subhorizontally plunges east-west. The F3 fold reoriented the original north-dipping S1 foliation and D2 shear sense into south-dipping S1 foliation(top-to-the west shear sense on this foliation) at its a limb. The four phase of deformation(D4) formed asymmetric-type open inclined fold(F4) of NE-vergence with NW striking axial plane(%) and NW-NNW plunging axis(L4). The F4 fold partly reoriented pre-D4 structural elements with east-west trend into those with north-south trend. Such reorientaion is recognized mainly in the Paleozoic metasedimentary rocks.

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Preparation and Characterization of Cobalt(III) Complexes with N,N,N',N'-Tetrakis(2-aminoethyl)-1,2-ethanediamines Ligand (,N,N',N'-Tetrakis(2-aminoethyl)-1,2-ethanediamine형 리간드를 포함하는 코발트 (III) 착물의 합성과 특성)

  • Myung-ki Doh;Byeoung-Su Choi;Chang-Rok An;Junnosuke Fujita
    • Journal of the Korean Chemical Society
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    • v.26 no.5
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    • pp.310-319
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    • 1982
  • Cobalt(III) complexes with sexidentate ligands, N,N,N',N'-tetrakis(2-amino-ethyl)-1,2-ethanediamine (ten), -1,3-propanediamine (ttn), -1,4-butanediamine (ttmd), -(R,R)-and -(R,S)-2,4-pentanediamine (tptn) were prepared, and the characterization of d-d absorption band on the variation of chelate ring size and conformation of these complexes were studied by means of electronic spectra. The first d-d absorption bands of $[Co(L)]^{3+}$ complexes are shifted to smaller wave numbers in the order. ttn > (R,R)-tptn > ten > ttmd${\simeq}$(R,S)-tptn for (L). The UV, $^{13}C$ NMR, and Circular Dichroism studies indicate that the R,S-tptn ligand of $[Co(R,S-tptn)]^{3+}$ complex coodinates to cobalt(Ⅲ) ion as a sexidentate with one methyl group in axial position.

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The Pharmacokinetics of Nimodipine After Oral Administration in Rabbits with Hepatic Failure

  • Choi, Jun-Shik;Choi, In;Burm, Jin-Pil
    • Journal of Pharmaceutical Investigation
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    • v.36 no.1
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    • pp.19-22
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    • 2006
  • The pharmacokinetics of nimodipine, following a single 16 mg/kg oral dose, was investigated in rabbits with hepatic failure induced by 0.5 mL/kg (mild), 1.0 mL/kg (moderate) and 2.0 mL/kg (severe) of carbon tetrachloride $(CCl_{4}$ : olive oil = 20 : 80, v/v). The plasma concentrations of nimodipine were determined by a high performance liquid chromatographic assay. The levels of sGOT and sGPT in rabbits with mild $(86.2{\pm}29.0\;and\;98.5{\pm}33.1\;unit/dL)$, moderate $(168.1{\pm}61.2\;and\;196.2{\pm}66.0\;unit/dL)$ and severe $(292.7{\pm}82.2\;and\;314.2{\pm}99.8\;unit/dL)$ hepatic failure were significantly increased compared to the control $(38.0{\pm}10.1\;and\;32.4{\pm}10.2\;unit/dL)$. The area under the plasma concentration-time curve (AUC) of nimodipine was significantly increased in mild $(131.7{\pm}28.1%)$, moderate $(168.8{\pm}32.8%)$ and severe $(204.6{\pm}58.3%)$ carbon tetrachloride-induced hepatic failure rabbits compared to the control (100%) rabbits. The volume of distribution $(V_{d})$ and the total body clearance $(CL_{t})$ of nimodipine were significantly decreased in all hepatic failure groups. The elimination rate constant $(K_{el})$ of nimodipine was significantly decreased in moderate and severe carbon tetrachloride-induced hepatic failure rabbits. There was a correlation between sGOT (y= 1.01x+241, r=0.993) or sGPT (y=0.92x +243, r=0.997) value and the AUC of nimodipine in the rabbits with hepatic failure. These findings suggest that the hepatic metabolism of nimodipine was inhibited by carbon tetrachloride-induced hepatic failure rabbits, resulting in the decrese in $V_{d}$ and $CL_{t}$ of nimodipine in the rabbits with mild, moderate and severe hepatic failure.

Separation Characteristics of Mandelic Acid in Kromasil HPLC Column (Kromasil HPLC 칼럼에서 Mandelic Acid의 분리특성)

  • Kim, Byung Lip;Kim, Jong Min;Kim, Woo Sik;Kim, In Ho
    • Korean Chemical Engineering Research
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    • v.46 no.4
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    • pp.681-685
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    • 2008
  • Chiral separation of racemic mandelic acid was achieved on a Kromasil KR100-5CHI-TBB column. Some chromatographic parameters (resolution, number of theoretical plates, capacity factor) are calculated under different separation conditions such as changes of mobile phase compositions (hexane/t-BME = 85/15 - 10/90) as well as formic acid concentrations for adjusting pH (0.1, 0.5, 1.0 v/v%). Flow rate versus number of theoretical plates was compared to evaluate column efficiency. To determine the adsorption isotherms, PIM (Pulse Input Method) was carried out. At the concentrations of racemic mandelic acid between 0.1 and 0.3 mg/ml, L- and D-mandelic acids have the same retention times of 8.8 and 9.4 min respectively. Mandelic acid isotherms show a linear form under the concentrations of 0.3 mg/ml with eluent (hexane/t-BME = 75/25). As the concentrations of mandelic acids increase, nonlinear Langmuir isotherms were observed as $C_{S,L}=3.358C_{M,L}/(1+0.0897C_{M,L})$ for L-mandelic acid and, $C_{S,D}=3.692C_{M,D}/(1+0.1457C_{M,D})$ for D-mandelic acid.