• Tuberculosis and Respiratory Diseases
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• 제67권6호
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• pp.491-498
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• 2009

Severe sepsis and septic shock are major healthcare problems with high mortality, ranging from 20% to 60%, affecting millions of individuals around the world each year. The speed and appropriateness of therapy administered in the initial hours after severe sepsis develops have an important impact on the outcome. In 2004, an international guideline that the bedside clinician could use to improve the outcomes in severe cases of sepsis and septic shock was published. Several landmark studies recently demonstrated that therapeutic strategies may reduce mortality substantially. The "Surviving Sepsis Campaign guidelines for management of severe sepsis and septic shock: 2008", using a new evidence-based methodology system for assessing the quality of evidence and the strength of the recommendations, was updated. The revised version is based on an updated search into 2007. Evidenced-based recommendations regarding the acute management of sepsis and septic shock are the first step toward improving the outcomes of critically ill patients. We review the treatment guidelines of sepsis and septic shock.

• Toxicological Research
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• 제21권4호
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• pp.271-278
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• 2005

Reproductive and developmental toxicology is concerned with various physical or chemical agents interfering with fertility in both gender or normal growth of offsprings. Reproductive and developmental toxicology is rather a complex science, with many fields, i.e., various endpoints are involved and many different mechanisms of action. For that reason, diverse aspects must be considered when attempting to assess possible adverse health effects in the area of reproductive and developmental toxicology. The thalidomide tragedy made it clear to regulatory authorities around the world that systematic, comprehensive evaluation of the reproductive cycle was needed to adequately evaluate the potential of medicinal drugs to impair the process of reproduction or the development of embryos, fetuses, and children. International Conference on Harmonization of Technical Requirements for the Registration of Pharmaceuticals for Human Use (ICH) and U.S. Food and Drug Administration (FDA) developed a guideline to assess the reproductive and developmental toxicity. Also these guidelines have since been applied to the detection and regulation of environmental toxicants, food additives, and so on. Although it was hoped that testing procedures of guideline would be updated constantly to reflect the current state of the science in reproductive and developmental toxicology, it was not until this decade that regulatory guidelines and testing methods have been altered in a significant way. In this paper, we would like to present the recommended approaches and recent trends for improvement of testing guidelines or experimental methods in reproductive and developmental toxicology.

• 한국환경과학회지
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• 제26권1호
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• pp.97-107
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• 2017

In the recent trend where crime types are being diversified along with urban expansion, we are facing the reality of a 'taking-it-out-on-somebody' crime, which targets the public rather than a specific person with criminal intent, like a 'random target crime.' A park, which is a public space for urban dwellers' and residents' leisure and rest in the midst of social changes, can be called the spot where various crimes occur. This is because it is a space without boundaries, available for the influx of many and unspecified persons, thus making it difficult to specify users. For the purpose of keeping a park safe from crime and providing users with psychological stability, this study carried out its research to get basic knowledge of the introduction of CPTED (Crime Prevention Through Environmental Design) concept in park development. The park development guideline contents are analyzed based on the six principles of CPTED theory as per the space composition element of a park. As a result, this study found out a problem was that most guidelines applied to the space composition element of a park were fragmentary in applying the six principles of CPTED theory, and were focused on arrangement and installation of facilities.

• 한국광학회지
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• 제22권3호
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• pp.141-150
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• 2011

현재까지 더 좋은 성능의 LED 램프 패키지 구조의 개발을 위해 많은 연구가 진행되어 왔음에도 불구하고 아직 LED 램프 패키지 설계에 관한 표준화된 이론이나 지침 같은 것들이 마련되지 못한 것으로 판단된다. 이에 본 논문에서는 먼저 Monte Carlo photon simulation 기법을 이용하여 InGaN/Sapphire LED의 칩 구조 및 Epi-up 혹은 Epi-down 칩 부착 방식을 광추출효율 관점에서 분석하였다. 그리고 분석결과를 바탕으로 LED 램프 패키지 설계에 관한 기본 지침을 마련하였다. 이와 같이 마련된 설계지침은 관련 기업이나 연구기관에서, LED 램프의 구체적 응용분야에 따라 최적화된 패키지 구조를 설계하는 데에 중요하게 활용될 수 있을 것으로 기대된다.

• 연구윤리
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• 제4권2호
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• pp.1-5
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• 2023

Purpose: There are already hundreds of millions of users of the Metaverse platform, and within a few years, it is expected to develop into a stage for new economic activities with huge industrial ripple effects due to the size of users. The purpose of this study is to derive considerations for the development of metaverse ethical guidelines. Research design, data, and methodology: The concept of the metaverse was examined through various opinions of industry and experts on the metaverse, and literature related to metaverse ethics was analyzed in the Korean journal database. Results: Six issues were identified through the existing research. (1) Establishing a unified definition of metaverse (2) Necessity of establishing ethical principles considering the operator (3) Personal information protection and privacy (4) Expression in a virtual environment (5) Copyright and intellectual property rights of creations (6) Virtual economy and fairness of trade. Conclusions: Metaverse ethics will be developed and implemented in a form and method different from the real world, but basically, continuous discussions on ethical rationality are needed in the process. In addition, since the ethical judgment in the metaverse environment accompanies cultural differences and epochal changes, it is necessary to focus on metaverse ethics cases.

• 산업경영시스템학회지
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• 제46권3호
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• pp.89-100
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• 2023

Recently, as ESG management has become an important issue, major companies in the automotive parts manufacturing industry are conducting ESG evaluations of their suppliers for the purpose of supply chain management. The results of these evaluations are being incorporated into contractual agreements. However, many small and medium-sized enterprises(SMEs) are lacking in their capacity and resources to effectively respond to ESG evaluations. Furthermore, existing ESG management guidelines do not provide an industry-specific guidance, making it necessary to establish industry-specific guidelines that SMEs can refer to. Therefore, in this study, the evaluation Indicators of ESG supply chain assessments are surveyed, which is conducted by domestic major automotive parts companies and global automobile manufacturers. Then 56 supply chain ESG evaluation Indicators are derived. Also, ESG management indicators for SMEs is analyzed through the Importance-Performance Analysis(IPA), based on an interview of expert groups. Therefore, this study could propose industry-specific ESG guidelines, based on the results of the derived indicators, which reflects the need for SMEs to practice ESG management within certain boundaries.

• Journal of Chest Surgery
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• 제57권1호
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• pp.1-24
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• 2024

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• 제18권2호
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• pp.85-87
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• 2007

The new research data and rapid development of psychotropic drugs over the past few years have warranted the development of clinical practice guidelines for managing pervasive developmental disorder(PDD). These guidelines are urgently needed due to the recent changes in social circumstances and clinical situations in Korea. Despite the many limitations and problems surrounding the development of these guidelines, the Korean Academy of Child and Adolescent Psychiatry(KACAP) has decided to develop the Korean Practice Parameters for the Treatment of PDD. The goal, basic principles, organization, and implications of this development project are introduced in this special paper. We expect these practice parameters to be a useful reference not only for child psychiatrists and other healthcare professionals in clinical practice, but also for the autistic patients themselves and their caregivers. The practice parameters shall be revised and improved in the near future.

• 한국문헌정보학회지
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• 제51권3호
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• pp.23-44
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• 2017

본 연구의 목적은 단위 학교도서관에서 장서관리정책을 수립할 때 근거 및 기준으로 삼을 수 있는 국가 수준의 학교도서관 장서관리지침서에 포함할 구체적인 항목과 내용 요소를 개발하는 것이다. 이를 위하여 학교도서관 장서관리 관련 문서를 국제 수준 및 국가 수준으로 나누어 분석하였다. 분석 결과 해외 장서관리지침서에서는 장서의 양적 기준 이외에 디지털 정보자원에 대한 접근성과 자원 공유를 강조하고 있으며, 이의 제기 자료에 대한 처리 절차를 규정하고 있는 것으로 나타났다. 본 연구에서는 국가 수준의 학교도서관 장서관리지침서가 포함해야 할 항목을 크게 장서관리의 일반 원칙과 장서관리지침으로 구분하고 각 항목별 내용 요소를 제안하였다. 그리고 국가 수준의 장서관리지침서가 학교 현장에 효율적으로 적용할 수 있는 제도적 기반 마련 방안을 제안하였다.

• 한국농공학회논문집
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• 제61권1호
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• pp.121-130
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• 2019

The purpose of this study is to determine the amount of irrigation water for upland crop growth based on the 30 year of historical rainfall data and the water management guidelines as a reference. Five regions and ten crops were selected by their cultivation size. The changes of soil moisture contents were calculated using daily mean rainfall and irrigation demand. This study assumed that crops are irrigated when the soil moisture contents fell below of the field capacity for more than 5 days, which is the drought condition defined by RDA. The maximum irrigation water requirements was 167.2 mm for chinese cabbage during the growing season, which was followed by corn (112.0 mm), daikon (102.3 mm), spinach (66.1 mm), lettuce (56.7 mm), pepper (46.5 mm), potato (33.9 mm), sweet tomato (27.4 mm), peanut (11.5 mm) and bean (10.3 mm), The results of this study could contribute to providing valuable data to determine the capacity of irrigation facilities and to establish the emergency operation plans under extreme unfavorable weather condition (heat wave, etc.) for crop growth.