Tuberculosis and Respiratory Diseases

The Korean Academy of Tuberculosis and Respiratory Diseases (대한결핵및호흡기학회)
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Treatment Guidelines of Sepsis and Septic Shock

패혈증과 패혈쇼크의 치료 지침

  • Lee, Heung Bum (Department of Internal Medicine, Research Institute of Clinical Medicine, Chonbuk National University Medical School) ;
  • Moon, Hee (Department of Internal Medicine, Research Institute of Clinical Medicine, Chonbuk National University Medical School)
  • 이흥범 (전북대학교 의과대학 내과학교실, 임상의학연구소) ;
  • 문희 (전북대학교 의과대학 내과학교실, 임상의학연구소)
  • Received : 2009.06.12
  • Accepted : 2009.06.15
  • Published : 2009.12.30
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Abstract

Severe sepsis and septic shock are major healthcare problems with high mortality, ranging from 20% to 60%, affecting millions of individuals around the world each year. The speed and appropriateness of therapy administered in the initial hours after severe sepsis develops have an important impact on the outcome. In 2004, an international guideline that the bedside clinician could use to improve the outcomes in severe cases of sepsis and septic shock was published. Several landmark studies recently demonstrated that therapeutic strategies may reduce mortality substantially. The "Surviving Sepsis Campaign guidelines for management of severe sepsis and septic shock: 2008", using a new evidence-based methodology system for assessing the quality of evidence and the strength of the recommendations, was updated. The revised version is based on an updated search into 2007. Evidenced-based recommendations regarding the acute management of sepsis and septic shock are the first step toward improving the outcomes of critically ill patients. We review the treatment guidelines of sepsis and septic shock.

Keywords

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