• Journal of Microbiology and Biotechnology
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• 제17권8호
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• pp.1330-1337
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• 2007

To better understand the gene expression of the cold-adapted polar diatom, we conducted a survey of the Chaetoceros neogracile transcriptome by cDNA sequencing and expression of interested cDNAs from the Antarctic diatom. A non-normalized cDNA library was constructed from the C. neogracile, and a total of 2,500 cDNAs were sequenced to generate 1,881 high-quality expressed sequence tags (ESTs) (accession numbers EL620615-EL622495). Based on their clustering, we identified 154 unique clusters comprising 342 ESTs. The remaining 1,540 ESTs did not cluster. The number of unique genes identified in the data set is thus estimated to be 1,694. Taking advantage of various tools and databases, putative functions were assigned to 939 (55.4%) of these genes. Of the remaining 540 (31.9%) unknown sequences, 215 (12.7%) appeared to be C. neogracile-specific since they lacked any significant sequence similarity to any sequence available in the public databases. C. neogracile consisted of a relatively high percentage of genes involved in metabolism, genetic information processing, cellular processes, defense or stress resistance, photosynthesis, structure, and signal transduction. From the ESTs, the expression of these putative C. neogracile genes was investigated: fucoxanthin chlorophyll (chl) a,c-binding protein (FCP), ascorbate peroxidase (ASP), and heat-shock protein 90 (HSP90). The abundance of ASP and HSP90 changed substantially in response to different culture conditions, indicating the possible regulation of these genes in C. neogracile.

• Fisheries and Aquatic Sciences
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• 제16권4호
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• pp.303-309
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• 2013

Microsatellite markers are important for gene mapping and for marker-assisted selection. Sixty-five polymorphic microsatellite markers were developed with an enriched partial genomic library from olive flounder Paralichthys olivaceus an important commercial fish species in Korea. The variability of these markers was tested in 30 individuals collected from the East Sea (Korea). The number of alleles for each locus ranged from 2 to 33 (mean, 17.1). Observed and expected heterozygosity as well as polymorphism information content varied from 0.313 to 1.000 (mean, 0.788), from 0.323 to 0.977 (mean, 0.820), and from 0.277 to 0.960 (mean, 0.787), respectively. Nine loci showed significant deviation from the Hardy-Weinberg equilibrium after sequential Bonferroni correction. Analysis with MICROCHECKER suggested the presence of null alleles at five of these loci with estimated null allele frequencies of 0.126-0.285. These new microsatellite markers from genomic libraries will be useful for constructing a P. olivaceus linkage map.

• 정보관리학회지
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• 제26권2호
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• pp.127-147
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• 2009

자연언어에서 유사어의 처리는 사람과 컴퓨터간의 의사소통에 적지 않은 장애가 되어왔고, 이는 사용자의 임의적 단어사용에 기반을 두고 있는 웹 2.0 애플리케이션, 특히 소셜태깅 분야에 있어서 그 장애의 정도가 더 심각해질 수 있다. 본 연구는 한 대표적인 웹 2.0 애플리케이션에서 자동 유사어 추출에 관한 문제를 다루고 있다. 더 구체적으로, 가장 널리 사용되는 소셜북마킹 애플리케이션인 딜리셔스를 기반으로, 유사태그를 추출하는 방법(FolkSim)을 제시하고자 한다. 제시한 방법의 평가를 위하여, 문서유사도의 측정을 위해서 쓰여진 고전적 벡터모델에 의거한 유사태그를 추출하는 방법(CosSim)과 그 결과들을 서로 비교분석하여 보았다. 몇 가지 면에서 FolkSim가 더 나은 결과 산출해내는 증거들이 관찰되어졌다. 또한, FolkSim 방법에 의한 유사태그가 만들어지지 않는 경우에 대비하여, 그 대안 또한 제시하고 있다.

• 한방재활의학과학회지
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• 제32권3호
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• pp.29-35
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• 2022

Objectives The purpose of this systematic review is to analyse randomized controlled trials about acupuncture for patellofemoral pain syndrome (PFPS) and evaluate it's pain improvement effect. Methods Studies will be searched from ten databases (Medline/PubMed, Cochrane Library, EMBASE, China National Knowledge Infrastructure [CNKI], WanFang Data, Citation Information by NII [CiNII], ScienceON, Koreanstudies Information Service System [KISS], KMBASE, and KoreaMed). Participants will be patients diagnosed with PFPS, regardless of cause, gender, age or race, and interventions will be acupuncture, electroacupuncture, dry needling, fire needle, and acupotomy. Other treatments than interventions will be the control group and the main outcome will be reviewed by visual analogue scale (VAS). Results Data will be extracted and assessed according to the Preferred Reporting Items for Systematic Review and Meta-Analysis flow chart and Cochrane risk of bias tools. Meta-analysis will be conducted using random effect model within 95% confidence interval. Conclusions We expect this systematic review to provide useful data about the pain improvements of patellofemoral pain using acupuncture and expect to stimulate and systematize acupuncture treatment on PFPS in the future.

• 한방재활의학과학회지
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• 제33권2호
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• pp.19-32
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• 2023

Objectives The purpose of this study is to systematically review the degree of pain and function improvement in acupuncture treatment for patellofemoral pain syndrome (PFPS). Methods Randomized controlled trials (RCTs) were searched from Medline/PubMed, Cochrane Library, Embase, WanFang Data, China National Knowledge Infrastructure (CNKI), Citation Information by NII (CiNII), Koreanstudies Information Service System (KISS), ScienceON, KoreaMed, and Korean Medical Database (KMbase). The methodological quality of selected RCTs' were evaluated according to Cochrane RoB2 tool. Results Total of 158 studies were identified and 7 RCTs were selected for systematic review. Frequently used evaluation method were visual analogue scale and Kujala scores. All studies showed significant effect on pain reduction and knee function between before and after treatment, but showed partial significance between the intervention and control group. Conclusions Research showed that acupuncture treatment is an effective treatment for improving the pain and function of PFPS, but it is difficult to conclude that it has a significant effect compared to other treatments. Selected studies included subjective evaluation indicators and the total of selected studies were small, so the interpretation of the results is limited. Also most of the included studies are evaluated to have some concerns of bias. Therefore, subsequent research should continously be done in more objective and systematic method.

• 한방재활의학과학회지
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• 제34권1호
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• pp.83-95
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• 2024

Objectives This review was conducted to evaluate the therapeutic effects of manual acupuncture (MA) for shoulder impingement syndrome (SIS). Methods We searched 12 electronic databases (DBpia, Korean studies Information Service System [KISS], Oriental Medicine Advanced Searching Integrated System [OASIS], Research Information Sharing Service [RISS], China National Knowledge Infrastructure [CNKI], CINAHL, Clinical Key, Cochrane Library, Embase, JAMA, PubMed, Web of Science) to find randomized-controlled clinical trials (RCTs) investigating therapeutic effects of MA for treating SIS. Shoulder Pain and Disability Index scores and numeric pain rating scale or visual analogue scale were analyzed as the main evaluation criteria. Results Among 181 studies, 169 were screened and only 12 RCTs were eligible in our review. Finally, 11 RCTs could be statistically analyzed. MA was more effective than sham treatment and physical therapy in terms of reducing pain (p=0.003, p=0.0007 each). Electroacupuncture (EA) showed more significant effect than physical therapy (PT) for improving shoulder pain (p<0.00001) and shoulder functionality (p<0.00001). Conclusions These results suggest that MA and EA could be superior option for treating SIS than sham treatment or PT. However this review has its limitations due to the small sample size and lack of well-designed RCTs that were included in the study. Further well-designed RCTs are necessary to provide high-level evidence.

• 공학교육연구
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• 제23권2호
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• pp.31-42
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• 2020

This study aims to analyze the research trends of female engineering students focused on domestic research and to suggest implications for future researches. For this purpose, 67 domestic researches (academic articles & graduate theses) which were published since 1996 were collected using the academic research information service and the National Assembly Library search service. All of these 67 researches have been reviewed and classified according to analytical criteria such as publication year, research method, journal's research field and research subjects. Our findings show that firstly, related research on female engineering students has been growing since 1996. Secondly, there were more researches of both academic journals and graduate theses, using quantitative method compared to those with the other research methods. Thirdly, the research themes could be classified as follows: gender-awareness, female engineering students'(hereafter, FES) psychological variables, customized education for FES, career related variables, FES's properties and counselling for them. Fourth, regarding the result of analysis on the research topic, 41.79% of the researches were related to FES's 'career' related factors as well as diverse correlates. Based on these findings, it is necessary to continue studying on FES using various research methods as well as adopting different research perspectives. Also, practical and educational treatments for FES are required with particular attention to their individual variables.

• 한국산학기술학회논문지
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• 제21권8호
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• pp.429-439
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• 2020

본 연구의 목적은 메타분석을 통해 가상현실 프로그램이 뇌졸중 환자의 상지기능에 미치는 효과크기를 알아보고자 한다. 데이터베이스는 한국교육학술정보원(RISS), 한국학술정보(KISS), 국립중앙도서관, 한국학술지인용색인(KCI), 국가과학기술정보센터(NDSL)를 활용하였다. 2010년 1월부터 2019년 6월까지 가상현실 프로그램을 실시한 선행연구들을 조사하였다. 본 연구는 PICO(Patient, Intervention, Comparison, Outcome, PICO)기준에 의거하여 최종 14편을 선정하여 메타분석을 실시하였다. 질 평가도구로 RCT(Randomized Control Trials) 연구는 RoB(Risk of Bias) 도구, NRCT(Non-Randomized Control Trials) 연구는 RoBANS(Risk of Bias Assessment tool for Non-randomised Study) 도구를 사용하였다. 선정된 각 연구들의 효과크기를 산출하기 위해 CMA 3.0프로그램을 사용하였다. 추가적으로 하위집단분석과 메타회귀분석 및 출판편의 분석을 실시하였다. 가상현실 프로그램이 상지기능에 대한 전체 효과크기는 Hedges's=0.390 (95 % CI: 0.192~0.587)으로 확인되었다(p<.05). 가상현실 프로그램은 뇌졸중 환자의 상지기능에 긍정적인 영향을 미친다. 따라서, 4차 산업에 발맞추어 뇌졸중 환자를 위한 다양한 가상현실 프로그램과 산학 협력 기술 개발이 요구된다. 향후 가상현실 프로그램에 대한 RCT연구들과 세부적인 상지기능에 대한 연구가 질적 및 양적으로 확보되어야 할 것이다.

• 농촌계획
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• 제29권4호
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• pp.81-92
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• 2023

The purpose of this study is to identify rural research topics, differences in research topics over time, and key mediators through the analysis of academic research trends using topic modeling. This study analyzed a total of 1,183 articles published in the Journal of Rural Planning and Rural Society over a 23-year period (2000-2022). We categorized rural research topics into 30, examined the proportion of research in each topic, and identified major changes in research topics over time. We also identified key words that mediate between research topics. The study found that, first, rural research trends can be categorized into five types (resources and utilization, area/space, people, ecosystem/environment, and tourism), with area/space being the most studied. Subtopics include rural amenities, rural disappearance/village miniaturization, and rural landscape management. Second, the research topics for each period were different. In the first period(2003-2007), the main research topics were rural amenities and Agricultural production- based climate vulnerability assessment. In the second period(2008-2012), the main research topics were Rural extinction and village depopulation, and rural landscape management, and in the third period(2013-2017), the main research topics were rural sixth industrialization and rural ecotourism. In the fourth period(2018-2022), rural development planning and rural life services(life SOC) were the main research topics. The significance of this study is that it extends the existing method of analyzing research trends and provides basic data to enhance comprehensive insights and understanding of rural research.

• 한국정보과학회논문지:시스템및이론
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• 제29권6호
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• pp.318-330
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• 2002

본 논문은 광주 크박스와 테잎 라이브러리 같은 Tertiary 저장 장치를 미디어 저장 장치로 사용하는 비디오 서버의 설계와 구현에 대하여 기술한다. Tertiary 저장 장치를 스트리밍 서버의 미디어 저장 장치로 사용하기 위해서는 Tertiary 저장 장치의 하드웨어적인 특성을 고려한 적절한 스트리밍 서비스 모델이 필요하다. 논문에서는 연속 미디어의 특성을 고려한 스트림 스케쥴링, 디스크 캐슁, 사용자 수용 제어 정책 등을 제안하고 이를 핵심으로 하는 스트리밍 서비스 모델을 제시한다. 제안된 시스템은 광주크박스 저장장치를 장착한 Windows 2000 플랫폼에서 구현되었고, 다양한 실험 및 성능 분석을 통해 제안된 정책들이 올바로 동작함을 검증하였다.