• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.18 no.4
• /
• pp.366-379
• /
• 2017

In this study, we performed a systematic review and meta-analysis to identify the effects of exercise on endothelial progenitor cells (EPCs) in patients with cardiovascular disease (CVD). We conducted database searches (Cochrane Library, PubMed, EMBASE, ScienceDirect, CINAHL, Scopus, KoreaMed, KISS, RISS, KMBASE) for the effect of exercise on cardiovascular disease, using heart disease, coronary artery disease, heart failure, cardiovascular disease, exercise, motor activity, rehabilitation, and endothelial progenitor cells as the keywords. Of the 539 studies identified, 9 met the inclusion and exclusion criteria. Comprehensive Meta-Analysis version 2.0 was used to analyze the effect size and the publication bias was checked with a funnel plot. Exercise was found to improve the VEGF (vascular endothelial growth factor), CD34+KDR+, and endothelial function, assessed via FMD (flow-mediated dilation), in the exercise vs. control groups, viz. 2.008 (95% CI 0.204-3.812), 1.399 (95% CI 0.310-2.489), and 1.881 (95% CI 0.848-2.914), respectively. Exercise improved the VEGF, number of EPCs, and endothelial function in the CVD patients. Considering the increasing prevalence and mortality rates for cardiovascular disease in Korea, the findings of this study that analyzed the effects of exercise on EPCs might provide guidelines for planning exercise interventions for patients with CVD.

• Journal of Society of Preventive Korean Medicine
• /
• v.20 no.3
• /
• pp.9-20
• /
• 2016

Background and objectives : Student support programs in Korean Medicine (KM) college have been not much activated as compared to other colleges. So, this research is aim to offer a baseline data to plan and run any kind of student support programs by understanding Korean Medicine students' preference and satisfaction. Methods : The survey was taken for 4 weeks from 2nd may 2016 to 27th may 2016, asking 162 out of a total of 255 students from $1^{st}$ grade to $6^{th}$ grade (pre-med to med). 3 Korean medicine doctors and 8 general students in Korean medicine college made the questionnaire by reviewing and modifying used questionnaire for student support programs. It consists of 13 questions (3 questions of demographic characteristics, 10 questions of overall awareness about student support programs). Results : 'Advanced clinical training course' was the most preferred with 23.4% among 13 different student support programs when multiple voting was allowed. 'Chinese Medicine college tour' got 21.6%, and 'Major training in Chinese Medicine college (for 17 days)' followed next with 19.4%. Expected satisfaction score to student support programs was 7.30 on average out of 10. Conclusions : Expected satisfaction to student support program was likely to be high. This research can be utilized as a significant assessment and analysis when developing new student support program for Korean Medicine college students.

• The Journal of Internal Korean Medicine
• /
• v.37 no.6
• /
• pp.929-939
• /
• 2016

Objectives: Strokes have diverse symptoms and signs. One of ten stroke patients has chronic pain after a stroke. Pain after a stroke interrupts rehabilitation and worsens quality of life, but there is no efficient treatment for this pain. This study surveyed and reports on the clinical studies of treatment for chronic pain after a stroke. Methods: We searched journals for reports on clinical studies of treatment for chronic pain after a stroke through the databases OASIS (http://oasis.kiom.re.kr), NDSL (ndsl.kr), Kmbase (http://kmbase.medric.or.kr/), and PubMed (http://www. pubmed.com). The search words were "stroke & pain", "jungpung中風 & pain", "pungbi風痺", "cerebral hemorrhage & pain", and "cerebral infarction & pain". Results: Twenty-nine studies of treatment for chronic pain after a stroke were found. Of these, 15 were randomized controlled trials, 10 were nonrandomized controlled trials, and 4 were "before and after" studies. Treatments were diverse, including acupuncture, electroacupuncture, herbal acupuncture, herbal medicine, and more. The treatment periods were longer than 3 weeks on average. Conclusions: These results show that good quality randomized controlled trials of treatment for chronic pain after a stroke are small in number. We need larger and more diverse studies of treatment for chronic pain after a stroke.

• Journal of the Institute of Electronics Engineers of Korea SD
• /
• v.46 no.11
• /
• pp.66-76
• /
• 2009

The motion estimation in video encoding system occupies the biggest part. So, we require the motion estimator with efficient structure for real-time operation. And for motion estimator's implementation, it is desired to design hardware module of an exclusive use that perform the encoding process at high speed. This paper proposes motion estimation detection block(MED), 41 SADs(Sum of Absolute Difference) calculation block, minimum SAD calculation and motion vector generation block based on parallel processing. The parallel processing can reduce effectively the amount of the operation. The minimum SAD calculation and MED block uses the pre-computation technique for reducing switching activity of the input signal. It results in high-speed operation. The MED and 41 SADs calculation blocks are composed of adder tree which causes the problem of critical path. So, the structure of adder tree has changed the most commonly used ripple carry adder(RCA) with carry skip adder(CSA). It enables adder tree to operate at high speed. In addition, as we enabled to easily control key variables such as control signal of search range from the outside, the efficiency of hardware structure increased. Simulation and FPGA verification results show that the delay of MED block generating the critical path at the motion estimator is reduced about 19.89% than the conventional strukcture.

• Journal of Korean Society of Occupational and Environmental Hygiene
• /
• v.25 no.2
• /
• pp.184-193
• /
• 2015

Objectives: This study focused on three aspects: characterizing concentrations of airborne particles by size distributions and asbestos fibers generated by various building materials; analyzing the characteristics of fibers produced by each simulation and asbestos fibers released from ACBMs; and investigating correlations of airborne asbestos fibers and particles generated and association of particle and asbestos concentrations. Methods: We selected three ACBMs including an insulation board, cement asbestos slate and wallboard. We constructed 4 scenarios; a) crushing with a hammer; b) cutting with a industrial knife; c) brushing with a metal brush; and d) tightening & loosening with a hand drill. We implemented one simulation for 30 seconds followed by 30 seconds resting period. We repeated a total of 5 cycles for 5 minutes. Results: The highest concentration of particulate & fibrous matters was from crushing with a hammer in each scenario followed by brushing with a metal brush, cutting with a industrial knife, and tightening & loosening with a hand drill. For ACBMs studied, asbestos concentrations were highest from an insulation board followed by cement asbestos slate, and wallboard. No difference in terms of concentration was found between an insulation board and asbestos slate. Fibers with $5{\sim}20{\mu}m$ in length were included in 76~90% of total fibrous matters. The distribution of the straight form fibers was greater than that of the curl form. About 90% of $PM_{Total}$ released from ACBMs was consisted of $PM_{10}$ while only 10% of $PM_{Total}$ was $PM_{2.5}$. Particulate matters like $PM_{2.5}$ was significantly correlated with fibrous matters($R^2=0.81$). Conclusions: We found ACBMs can significantly release asbestos fibers as well as $PM_{2.5}$. Concentrations of asbestos generated by ACBMs were well correlated with $PM_{2.5}$.

• Proceedings of the Korean Society of Plant Biotechnology Conference
• /
• 2005.04a
• /
• pp.166-166
• /
• 2005

• Proceedings of the Korean Society of Veterinary Pathology Conference
• /
• 2003.10a
• /
• pp.18-18
• /
• 2003

Hepatitis C virus (HCV) has become a major public health issue and is prevalent in most countries. HCV infection starts frequently without clinical symptoms, and progresses in the majority of patients (70 to 85％) to persistent viremia and chronic hepatitis including cirrhosis and hepatocellularcarcinoma (HCC) [1]. Alcohol is one of the independent cofactors accelerating the development of HCC in chronic hepatitis C patients. This is of great interest because a synergy between excessive alcohol intake and HCV infection has been documented in the development of HCC in chronic hepatitis C patients [2]. The aim of this study is to investigate liver changes in ethanol feeding HCV-transgenic (Tg) mouse and to establish an animal model system. (omitted)

• Applied Microscopy
• /
• v.13 no.1
• /
• pp.31-40
• /
• 1983

Ultrathin sections of intact mycelia, released protoplast and fused protoplast of Micromonospora rosaria were observed by electron microscopy Intact mycelia showed a typical gram-positive bacterial cell wall structure and mesosomes. Released protoplasts had no cell wall components and fibrous nuclear region was distinguished from cytoplsmic region clearly. Protoplasts which treated with sucrose supplemented buffer were stable. But those treated with buffer without sucrose were extensively damaged, forming mom braneous vesicles. It was surmised that those vesicles originated from the damaged cytoplasmic membrane. High frequency of fusion was achieved by 50%(w/v). polyethylene-glycol 1,000 Fusion bodies in different stage of fusion were observed. Cell membrane barrier was stepwise relieved.

• Proceedings of the Korean Society of Toxicology Conference
• /
• 2003.10b
• /
• pp.118-118
• /
• 2003

The influence of dietary supplementation with dehydroepiandrosterone-sulphate (DHEA-S) at 0.6% was investigated in male Syrian golden hamsters initiated by treatments with azoxymethane(AOM), and dihydroxy-di-n-propyl nitrosamine (DHPN), timed after transfer from a choline-deficient to a normal diet.(omitted)

• Journal of Hospice and Palliative Care
• /
• v.24 no.3
• /
• pp.144-153
• /
• 2021

Purpose: Advance care planning (ACP) is widely understood to improve end-of-life care. This systematic review and meta-analysis aimed to examine the effects of ACP interventions on decision conflict and psychological distress. Methods: A search of PubMed, CINAHL, CENTRAL, EMBASE, KISS, KoreaMed, and RISS was conducted in November 2020. The study included randomized controlled trials. Data were pooled using fixed- and random-effects models. Results: Fourteen studies were identified that cumulatively included 1,548 participants. ACP interventions were effective in alleviating decision conflict (d=-0.53; 95% CI: -0.83 to -0.23), depression (d=-1.22; 95% CI: -1.71 to -0.74) and anxiety (d=-0.76; 95% CI: -1.12 to -0.39). Conclusion: ACP interventions have significant positive effects on reducing decision conflict and psychological distress. A high level of bias was shown related to allocation concealment and blinding. The results of this study are expected to be useful for end-of-life care providers to improve the effectiveness of ACP interventions.