• Title/Summary/Keyword: Kim Se Yeon

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Lomens-P0 (mixed extracts of Hordeum vulgare and Chrysanthemum zawadskii) regulate the expression of factors affecting premenstrual syndrome symptoms

  • Lee, Yoon Seo;Jeon, Hyelin;Her, Yang-Mi;Lee, Da Eun;Jeong, Yong Joon;Kim, Eun Jeong;Choe, Tae Hwan;Suh, Hee Ju;Shin, Seung-Yeon;Park, Dae Won;Lee, Yeong-Geun;Kang, Se Chan
    • Nutrition Research and Practice
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    • v.15 no.6
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    • pp.715-731
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    • 2021
  • BACKGROUND/OBJECTIVES: Premenstrual syndrome (PMS) is a disorder characterized by repeated emotional, behavioral, and physical symptoms before menstruation, and the exact cause and mechanism are uncertain. Hyperprolactinemia interferes with the normal production of estrogen and progesterone, leading to PMS symptoms. Thus, we judged that the inhibition of prolactin hypersecretion could mitigate PMS symptoms. MATERIALS/METHODS: Hordeum vulgare L. extract (HVE), Chrysanthemum zawadskii var. latilobum extract (CZE), and Lomens-P0 the mixture of these extracts were tested in subsequent experiments. The effect of extracts on prolactin secretion at the in vitro level was measured in GH3 cells. Nitric oxide and pro-inflammatory mediator expression were measured in RAW 264.7 cells to confirm the anti-inflammatory effect. Also, the hyperprolactinemic Institute for Cancer Research (ICR) mice model was used to measure extract effects on prolactin and hormone secretion and uterine inflammation. RESULTS: Anti-inflammatory effects of and prolactin secretion suppress by HVE and CZE were confirmed through in vitro experiments (P < 0.05). Treatment with Lomens-P0 inhibited prolactin secretion (P < 0.05) and restored normal sex hormone secretion in the hyperprolactinemia mice model. In addition, extracts significantly inhibited the expression of pro-inflammatory biomarkers, including interleukin-1𝛽, and -6, tumor necrosis factor-𝛼, inducible nitric oxide synthase, and cyclooxygenase-2 (P < 0.01). We used high-performance liquid chromatography analyses to identify tricin and chlorogenic acid as the respective components of HVE and CZE that inhibit prolactin secretion. The Lomens-P0, which includes tricin and chlorogenic acid, is expected to be effective in improving PMS symptoms in the human body. CONCLUSIONS: The Lomens-P0 suppressed the prolactin secretion in hyperprolactinemia mice, normalized the sex hormone imbalance, and significantly suppressed the expression of inflammatory markers in uterine tissue. This study suggests that Lomens-P0 may have the potential to prevent or remedy materials to PMS symptoms.

Analysis of Water Quality Variation by Lowering of Water Level in Gangjeong-Goryong Weirin Nakdong River (낙동강 강정고령보 수위저하 운영에 따른 수질 변동특성 분석)

  • Park, Dae-Yeon;Park, Hyung-Seok;Kim, Sung-Jin;Chung, Se-Woong
    • Journal of Environmental Impact Assessment
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    • v.28 no.3
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    • pp.245-262
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    • 2019
  • The objectives of this study were to construct a three-dimensional water quality model (EFDC) for the river reach between Chilgok Weir and Gangjeong-Goryong Weir (GGW) located in Nakdong River, and evaluate the effect of hydraulic changes, such as water level and flow velocity, on the control of water quality and algae biomass. After calibration, the model accurately simulated the temporal changes of the upper and lower water temperatures that collected every 10 minutes, and appropriately reproduced changes in organic matter, nitrogen, phosphorus, and cyanobacteria. However, the simulated values were overestimated for the diatoms and green algae cell density, possibly due to the uncertainties of the parameters associated with algae metabolism and the lack of zooplankton predation function in the simulations. As a result of scenario simulation of running the water level of GGW from EL. 19.44 m to EL. 14.90 m (4.54 m drop), Chl-a and algae cell density decreased significantly.In particular,the cyanobacteria on the surface layer, which causes algal bloom, declined by 56.1% in the low water level scenario compared to the existing management level. The results of this study are in agreement with the previous studies that maintenance of critical flow velocity is effective for controlling cyanobacteria, and imply that hydraulic control such as decrease of water level and residence time in GGW is an alternative to limit the overgrowth of algae.

A Study on the Performance Improvement of Software Digital Filter using GPU (GPU를 이용한 소프트웨어 디지털 필터의 성능개선에 관한 연구)

  • Yeom, Jae-Hwan;Oh, Se-Jin;Roh, Duk-Gyoo;Jung, Dong-Kyu;Hwang, Ju-Yeon;Oh, Chungsik;Kim, Hyo-Ryoung
    • Journal of the Institute of Convergence Signal Processing
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    • v.19 no.4
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    • pp.153-161
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    • 2018
  • This paper describes the performance improvement of Software (SW) digital filter using GPU (Graphical Processing Unit). The previous developed SW digital filter has a problem that it operates on a CPU (Central Processing Unit) basis and has a slow speed. The GPU was introduced to filter the data of the EAVN (East Asian VLBI Network) observation to improve the operation speed and to process data with other stations through filtering, respectively. In order to enhance the computational speed of the SW digital filter, NVIDIA Titan V GPU board with built-in Tensor Core is used. The processing speed of about 0.78 (1Gbps, 16MHz BW, 16-IF) and 1.1 (2Gbps, 32MHz BW, 16-IF) times for the observing time was achieved by filtering the 95 second observation data of 2 Gbps (512 MHz BW, 1-IF), respectively. In addition, 2Gbps data is digitally filtered for the 1 and 2Gbps simultaneously observed with KVN (Korean VLBI Network), and compared with the 1Gbps, we obtained similar values such as cross power spectrum, phase, and SNR (Signal to Noise Ratio). As a result, the effectiveness of developed SW digital filter using GPU in this research was confirmed for utilizing the data processing and analysis. In the future, it is expected that the observation data will be able to be filtered in real time when the distributed processing optimization of source code for using multiple GPU boards.

Morphological Characteristics of Needle Leaves and Analysis of Abies species based on Chloroplast DNA Sequences (한국 전나무(Abies holophylla), 일본 전나무(A. firma, A. homolepis), 그리고 법정 보호 전나무의 잎 형태적 특성 및 엽록체 DNA 분석)

  • Ahn, Chang Ho;Choi, Yong Eui;Park, Wan Geun;Han, Jung Yeon;Kwak, Yoo Shin;Kim, Se Chang;Park, Chan Woo
    • Journal of Korean Society of Forest Science
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    • v.108 no.2
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    • pp.200-207
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    • 2019
  • The aim of this study was to provide the basic information necessary to identify Korean fir (Abies holophylla), momi fir (A. firma), and Nikko fir (A. homolepis), and other fir trees planted in South Korea that are protected by law. Analysis of the morphological characteristics of the needles from each sample was investigated. The shape of the needle-leaf tip from A. holophylla was acute, whereas that from A. firma and A. homolepis was emarginate and that from the protected fir trees was obtuse. The number of stomata on the needles was not significantly different between A. holophylla and A. firma, and the number of stomata on the needles from A. homolepis and the protected fir trees were highly similar. In addition, the genetic differences among the Abies species were analyzed using the sequences of five chloroplast DNA regions-matK, atpF-atpH, rpoC2-rps2, rpoC1, and psbA-trnH.The atpF-atpH and psbA-trnH regions were useful for discriminating A. firma from the other species, but there were no differences among A. holophylla, A. homolepis, and the protected fir trees. The same chloroplast sequences were found in both A. holophylla and A. homolepis, which suggests that additional genetic studies might be necessary to identify the Abies species planted in both South Korea and Japan.

Investigation on the Farm Management and Livestock House Design Standard Perception to Enhance Usage of Livestock House Design Standard (축사표준설계도의 활용도를 높이기 위한 농가 운영 현황 및 축사표준설계도 인식 조사)

  • Kang, Sol-moe;Lee, In-bok;Hwang, Chang-kyu;Hwang, Soo-jin;Jeong, Deuk-young;Lee, Sang-yeon;Park, Se-jun;Choi, Young-bae;Kim, Da-in
    • Journal of The Korean Society of Agricultural Engineers
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    • v.64 no.6
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    • pp.87-99
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    • 2022
  • The meat consumption per person has continuously increased in recent years. However, the labor force in the domestic livestock industry has decreased due to the declining and ageing population. In order to increase productivity, the government have developed and distributed design standard of livestock houses. Presently, report showed that the adaptation rate of the developed livestock house design standard on the real farm was still low. Thus, this paper aimed to find ways to improve the utilization of the design standard through surveys. The survey was conducted on 650 farms across the country. Analysis of the result showed that in the poultry house, the unawareness of farmers to the design standard was found to be the biggest reason for not using the design standards. On the other hand, in the swine house, the previously built swine houses do not fit with the design standard. From these result, the following recommendations were suggested: 1) promotion and education are needed to enhance usage of design standard; 2) since it is impossible to make a design standard considering all the farm sites, it is important to consider the conditions of various farm site prior to enhancement of the design standard; 3) improvement factors such as reinforcing the ventilation design, reflecting animal welfare, preventing livestock diseases, and enhancing ICT devices can also be promoted.

Development of the Teaching-Learning Process Plan for 'Adolescent Nutrition and Dietary Behavior' of Middle School Technology and Home Economics through the Use of 'Blended Learning' Teaching Method (블렌디드 러닝을 활용한 중학교 기술·가정 '청소년기 영양과 식행동' 단원의 교수·학습과정안 개발)

  • Baek, Hee Yeon;Yoo, Se Jong;Kim, Yookyung
    • Journal of Korean Home Economics Education Association
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    • v.33 no.4
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    • pp.119-137
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    • 2021
  • This study aimed to develop a teaching-learning process plan for the 'adolescent nutrition and dietary behavior' unit of middle school technology and home economics through blended learning teaching method. "Analysis-Design-Development-Evaluation and Revision" model developed by Korea Institute of Curriculum and Evaluation(KICE) was applied to developing the teaching-learning process plan. The authors analyzed subject contents suitable for blended learning, and then designed a teaching-learning process plan by selecting the topics, developing the teaching strategies, and deciding on the media and evaluation tools for each class. Based on the plan for each week, the final version of the teaching-learning process plan, handouts for activities, and evaluation tools were developed. The teaching-learning process plan was revised and supplemented based on the expert verification results. The developed teaching-learning process plan which applied blended learning method was considered suitable for the current curriculum, and the group presentation activities implimented in the online classes were found to encourage learners' participation and interest. Also, the developed teaching-learning process plan could be used in the online only environment without any issues depending on the intention of the classes, by the appropriate use of distance learning tools such as Paddles or Thinkerbells. The developed teaching-learning course plan is expected to be effectively used in either online or blended learning environment, as a means of helping adolescent students improve their dietary life.

The Effect of Intrinsic Foot Muscles Strengthening Exercise on the Balancing Ability and the Height of Navicular Bone in Adults with Flexible Flatfoot on Unstable Surface (불안정한 지면에서 발 내재근 강화운동이 유연성 편평발을 가진 성인의 균형능력과 발배뼈 높이에 미치는 효과)

  • Ju-Hyun Lee;Min-Seok Kim;Soo-Bin Shin;Chan-Young Lee;Seo-Yeon Chae;Yu-Jin Hong;Se-Jung Oh
    • Journal of the Korean Society of Physical Medicine
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    • v.18 no.2
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    • pp.61-70
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    • 2023
  • PURPOSE: This study evaluated an intrinsic foot strengthening exercise method for flat feet by comparing the effects of intrinsic exercises on a stable surface and intrinsic exercises on an unstable surface. METHODS: Twenty-four people with flat feet were divided into two groups. The control group performed short foot exercises and toe towel curl exercises on the stable support surface. The experimental group performed short foot exercises and toe towel curl exercises on an unstable support surface using Aerostep. The navicular drop test, and the static and dynamic balance were measured before and after the intervention. RESULTS: In the experimental and control groups, there was a significant difference in the navicular drop test and static balance before and after the intervention (p < .05). On the other hand, there was no significant difference between the two groups (p > .05). In the dynamic balance, the experimental group showed significant differences in all directions after the intervention (p < .05). The control group showed significant differences in the postero-lateral direction and posteromedial direction (p < .05). In particular, in the forward direction, the experimental group had a more significant change than the control group (p < .05). CONCLUSION: Intrinsic foot muscle strengthening exercises performed on unstable surfaces can be an effective clinical exercise method to improve the dynamic balance ability of people with flat feet.

Dewatering of Sewage Sludge by Electrokinetics (동전기를 이용한 슬러지 탈수에 관한 연구)

  • Kim, Ji Tae;Won, Se Yeon;Cho, Won Cheol
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.26 no.6B
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    • pp.661-667
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    • 2006
  • In this study, an experiment of sewage sludge dewatering is carried by using electrokinetic method, and the electrokinetic dewatering efficiency of digested sludge is analyzed. Digested sludge without coagulants is selected and gravitational and pressing dewatering methods are applied in combination with electro-osmotic and electro-osmotic pulse technology. After the test of digested sludge, dewatering test of thickened sludge is carried to evaluate the electrokinetic dewatering feasibility of thickened sludge. Under the condition of constantly applied voltage, however, electrical resistance increases with decreasing of water content so that dewatering rate decreases with time. To reduce such a hindrance caused by constantly applied voltage, electro-osmotic pulse technology which is considered to reduce the difference of water content with height, is applied. For the application of electro-osmotic pulse, the dewatered flow rate and the dewatered volume became more increasing from the middle of the dewatering process than that of continuous voltage. Through the test of thickened sludge, electro-osmotic dewatering combined with gravitational and expression also showed high dewatering rate, which proved the possibility of using electrokinetic dewatering.

Full mouth rehabilitation with fixed prostheses by increased vertical occlusal dimension using 3D printed splint in a patient with excessive tooth wear (과도한 치아 마모 환자의 3D 프린팅 교합안정장치를 이용한 수직 교합 고경 증가를 동반한 고정성 보철물 전악 수복 증례)

  • Se-Young Kim;Soo-Yeon Shin
    • The Journal of Korean Academy of Prosthodontics
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    • v.61 no.3
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    • pp.215-226
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    • 2023
  • Severe wear of the anterior teeth facilitates the loss of anterior guidance, which protects the posterior teeth from wear during excursive movement. Additionally, when treating patients with collapsed occlusion due to multiple tooth loss and tooth wear, it is important to determine the presence of vertical dimension loss through accurate clinical and radiographic examinations and diagnostic wax-up. The patient of this case is a 44-year-old female patient who complained of overall tooth wear and loss of posterior teeth due to bruxism and clenching habits, visited the hospital with the address of restoring masticatory function and improving aesthetic appearance through prosthetic treatment. Through model analysis and diagnostic wax-up, an increase in vertical dimension was determined, and full mouth restoration with fixed prostheses was planned. The degree of adaptation to the vertical dimension was confirmed step by step using an occlusal splint designed with CAD (Computer aided design) software and 3-D (3-Dimensional) printed, and then restored with provisional restoration and after a 4-month adaptation period, the entire dentition was restored with metal ceramic crowns and implants. Through this procedure, satisfactory treatment results were obtained in terms of function and aesthetics.

Distal Soft Tissue Procedure in Hallux Valgus Deformity: Comparison of Modified Mcbride Procedure and Trans-Articular Approach (무지외반증에서의 원위 연부 조직 유리술: 변형된 맥브라이드 술식과 경관절 접근법의 비교)

  • JunYeop Lee;KwangYeon Kim;Se-Jin Park
    • Journal of Korean Foot and Ankle Society
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    • v.27 no.4
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    • pp.123-130
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    • 2023
  • Purpose: "Hallux valgus" is a common disease encountered in clinical practice and is accompanied by foot deformities. Conservative treatment is commonly used in the early stages of hallux valgus. On the other hand, surgical treatment often becomes necessary as the deformity progresses. Surgical treatments involve various osteotomy methods or joint fusion procedures combined with soft tissue release, and outcomes from these surgical treatments are generally favorable. This study compared two soft tissue release techniques in the hallux region. Materials and Methods: This study conducted a retrospective cohort study on 48 participants who underwent surgical treatment for hallux valgus at a single institution from March 1, 2018, to March 31, 2023. A scarf osteotomy was performed in all cases, and the "Modified Mcbride procedure" or "Trans-articular approach" was done for soft tissue release. Hallux valgus angle (HVA), intermetatarsal angle (IMA), and the degree of subluxation of the lateral sesamoid were measured through simple foot radiographs taken before surgery and one year after surgery. Results: In the Modified Mcbride procedure group, HVA, IMA, and the sesamoid position grade decreased from 34.94° to 9.98°, 15.64° to 5.44°, and 2.47 to 0.44, respectively. In the trans-articular approach group, HVA, IMA, and the sesamoid position grade decreased from 33.42° to 7.34°, 15.06° to 6.03°, and 2.17 to 0.58, respectively. There was no significant difference in these changes between the preoperative and one-year postoperative measurements for both techniques (p-value>0.05). Conclusion: A radiological assessment of soft tissue release through the Modified Mcbride procedure and trans-articular approach in hallux valgus did not show significant differences. Therefore, both surgical techniques can be considered in the distal soft tissue release for a hallux valgus correction.