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Genome-wide association study for loin muscle area of commercial crossbred pigs

  • Menghao Luan;Donglin Ruan;Yibin Qiu;Yong Ye;Shenping Zhou;Jifei Yang;Ying Sun;Fucai Ma;Zhenfang Wu;Jie Yang;Ming Yang;Enqin Zheng;Gengyuan Cai;Sixiu Huang
    • Animal Bioscience
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    • v.36 no.6
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    • pp.861-868
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    • 2023
  • Objective: Loin muscle area (LMA) is an important target trait of pig breeding. This study aimed to identify single nucleotide polymorphisms (SNPs) and genes associated with LMA in the Duroc×(Landrace×Yorkshire) crossbred pigs (DLY). Methods: A genome-wide association study was performed using the Illumina 50K chip to map the genetic marker and genes associated with LMA in 511 DLY pigs (255 boars and 256 sows). Results: After quality control, we detected 35,426 SNPs, including six SNPs significantly associated with LMA in pigs, with MARC0094338 and ASGA0072817 being the two key SNPs responsible for 1.77% and 2.48% of the phenotypic variance of LMA, respectively. Based on previous research, we determined two candidate genes (growth hormone receptor [GHR] and 3-oxoacid Co A-transferase 1 [OXCT1]) that are associated with fat deposition and muscle growth and found further additional genes (MYOCD, ARHGAP44, ELAC2, MAP2K4, FBXO4, FBLL1, RARS1, SLIT3, and RANK3) that are presumed to have an effect on LMA. Conclusion: This study contributes to the identification of the mutation that underlies quantitative trait loci associated with LMA and to future pig breeding programs based on marker-assisted selection. Further studies are needed to elucidate the role of the identified candidate genes in the physiological processes involved in LMA regulation.

Analysis on the Rainfall Driven Slope Failure Adjacent to a Railway : Flume Tests (강우로 인한 철도 연변사면의 활동분석 : 실내모형실험)

  • SaGong Myung;Kim Min-Seok;Kim Soo-Sam;Lee In-Yong
    • Journal of the Korean Geotechnical Society
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    • v.22 no.5
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    • pp.83-91
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    • 2006
  • Recently, the intensive rainstorm possibly induced by global warming plays a key role on the instability of railway adjacent slopes. The instability of slopes results as covering and loss of railway lines induced by slided soil mass. According to the site investigation on the failed slopes triggered by rainfall, low types of slope failure were observed: shallow, intermediate, gully erosion, and soil-rock interface failures. The observation reveals the different characteristics of slope failure depending on the thickness of soil layer, morphological features of slope, etc. Based upon the observations, flume tests were conducted to analyze the sliding mechanism of each failure. The variables of flume test are soil layer thickness, rainfall intensity, and morphology of slope under the constant condition of the percentage of fine, initial soil moisture content, slope angle and compaction energy. Test results show that shallow failure was mostly observed from the surface of the slope and caused by the soil erosion; in addition, compared to the other types of failure, the occurrence of initial erosion is late, however, the development of erosion is fast. In gully erosion failure, the collected water from the water catchment area helps erosion of the upper soil layer and transfer of residual corestone, which impedes the erosion process once the upper soil layers are eroded and corestone are exposed. The soil-rock interface failure shows the most fast initial erosion process among the failure types. Interestingly, the common feature observed from the different types of failure was the occurrence of the initial deformation near the toe of slopes which implies the existence of surbsurface flow along the downslope direction.

The Relationship between Participative Leadership and Subordinates' Innovative Behavior: The Serial Multiple Mediating Effects of Knowledge Sharing and Creativity (참여적 리더십이 구성원의 혁신행위에 미치는 영향: 지식공유와 창의성의 직렬다중 매개효과)

  • Le Wang;Xiu, Jin
    • Journal of Industrial Convergence
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    • v.21 no.4
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    • pp.41-63
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    • 2023
  • Organizational members' innovative behavior is a key element that promotes organizational growth and sustainability. With today's unstable environment of economic and market , the importance of employees' innovative behavior is being emphasized. The reason is that employees' innovative behaviors play an important role in securing a organizational competitiveness. Based on this, this study focused on ways to improve employees' innovation behavior. Specifically, the causal relationship between participatory leadership and employees' innovative behavior was identified and the influence of innovative behavior was also verified. Furthermore, in the process of participatory leadership influencing employees' innovative behavior, the serial multiple mediating effect of knowledge sharing and creativity was verified. In order to demonstrate the hyphotheses, this study focused on 237 employees who work in Chinese SMEs. The results of the empirical analysis showed that participatory leadership had a positive effect on knowledge sharing, creativity, and innovative behavior. In addition, the serial multiple mediating effects of knowledge sharing and creativity on the relationship between participatory leadership and innovative behavior was significant. Overall, this study verified the positive role of participatory leadership that enhances employees' innovative behavior in Chinese SMEs and contributed to expanding the research field related to employees' innovative behavior through serial multiple mediating model.

Factors Influencing Users' Payment Decisions Regarding Knowledge Products on the Short-Form Video Platform: A Case of Knowledge-Sharing on TikTok (짧은 영상 플랫폼에서 지식상품에 대한 사용자의 구매결정에 영향을 미치는 요인: TikTok의 지식 공유 사례)

  • Huimin Shi;Joon Koh;Sangcheol Park
    • Knowledge Management Research
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    • v.24 no.1
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    • pp.31-49
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    • 2023
  • TikTok, as a leading short video platform, has attracted many users, and the resulting attention generates immense business value as a platform to diffuse knowledge. As a qualitative and explorative approach, this study reviews the knowledge payment industry and discusses the influential factors of users' payment decisions regarding knowledge products on TikTok. By conducting in-depth interviews with ten participants and observing 95 knowledge providers' videos, we find that TikTok has significant business potential in the knowledge payment industry. By using the ATLAS. ti software to code the data collected from these interviews, this study finds that demander characteristics (personal needs), product characteristics (product quality), provider characteristics (the key opinion leader effect), and platform characteristics (platform management) are the four core categories that influence users' payment decisions regarding knowledge products on TikTok. A theoretical model consisting of the ten variables of emotional needs, professional needs, quality, price, helpfulness, value, charisma, user trust, service guarantee, and scarcity is proposed based on the grounded theory. The theoretical and practical implications of the study findings are also discussed.

A SVR Based-Pseudo Modified Einstein Procedure Incorporating H-ADCP Model for Real-Time Total Sediment Discharge Monitoring (실시간 총유사량 모니터링을 위한 H-ADCP 연계 수정 아인슈타인 방법의 의사 SVR 모형)

  • Noh, Hyoseob;Son, Geunsoo;Kim, Dongsu;Park, Yong Sung
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.43 no.3
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    • pp.321-335
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    • 2023
  • Monitoring sediment loads in natural rivers is the key process in river engineering, but it is costly and dangerous. In practice, suspended loads are directly measured, and total loads, which is a summation of suspended loads and bed loads, are estimated. This study proposes a real-time sediment discharge monitoring system using the horizontal acoustic Doppler current profiler (H-ADCP) and support vector regression (SVR). The proposed system is comprised of the SVR model for suspended sediment concentration (SVR-SSC) and for total loads (SVR-QTL), respectively. SVR-SSC estimates SSC and SVR-QTL mimics the modified Einstein procedure. The grid search with K-fold cross validation (Grid-CV) and the recursive feature elimination (RFE) were employed to determine SVR's hyperparameters and input variables. The two SVR models showed reasonable cross-validation scores (R2) with 0.885 (SVR-SSC) and 0.860 (SVR-QTL). During the time-series sediment load monitoring period, we successfully detected various sediment transport phenomena in natural streams, such as hysteresis loops and sensitive sediment fluctuations. The newly proposed sediment monitoring system depends only on the gauged features by H-ADCP without additional assumptions in hydraulic variables (e.g., friction slope and suspended sediment size distribution). This method can be applied to any ADCP-installed discharge monitoring station economically and is expected to enhance temporal resolution in sediment monitoring.

Social Perception of the Invention Education Center as seen in Big Data (빅데이터 분석을 통한 발명 교육 센터에 대한 사회적 인식)

  • Lee, Eun-Sang
    • Journal of the Korea Convergence Society
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    • v.13 no.1
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    • pp.71-80
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    • 2022
  • The purpose of this study is to analyze the social perception of invention education center using big data analysis method. For this purpose, data from January 2014 to September 2021 were collected using the Textom website as a keyword searched for 'invention+education+center' in blogs, cafes, and news channels of NAVER and DAUM website. The collected data was refined using the Textom website, and text mining analysis and semantic network analysis were performed by the Textom website, Ucinet 6, and Netdraw programs. The collected data were subjected to a primary and secondary refinement process and 60 keywords were selected based on the word frequency. The selected key words were converted into matrix data and analyzed by semantic network analysis. As a result of text mining analysis, it was confirmed that 'student', 'operation', 'Korea Invention Promotion Association', and 'Korean Intellectual Property Office' were the meaningful keywords. As a result of semantic network analysis, five clusters could be identified: 'educational operation', 'invention contest', 'education process and progress', 'recruitment and support for business', and 'supervision and selection institution'. Through this study, it was possible to confirm various meaningful social perceptions of the general public in relation to invention education center on the internet. The results of this study will be used as basic data that provides meaningful implications for researchers and policy makers studying for invention education.

Introducing Keyword Bibliographic Coupling Analysis (KBCA) for Identifying the Intellectual Structure (지적구조 규명을 위한 키워드서지결합분석 기법에 관한 연구)

  • Lee, Jae Yun;Chung, EunKyung
    • Journal of the Korean Society for information Management
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    • v.39 no.1
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    • pp.309-330
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    • 2022
  • Intellectual structure analysis, which quantitatively identifies the structure, characteristics, and sub-domains of fields, has rapidly increased in recent years. Analysis techniques traditionally used to conduct intellectual structure analysis research include bibliographic coupling analysis, co-citation analysis, co-occurrence analysis, and author bibliographic coupling analysis. This study proposes a novel intellectual structure analysis method, Keyword Bibliographic Coupling Analysis (KBCA). The Keyword Bibliographic Coupling Analysis (KBCA) is a variation of the author bibliographic coupling analysis, which targets keywords instead of authors. It calculates the number of references shared by two keywords to the degree of coupling between the two keywords. A set of 1,366 articles in the field of 'Open Data' searched in the Web of Science were collected using the proposed KBCA technique. A total of 63 keywords that appeared more than 7 times, extracted from 1,366 article sets, were selected as core keywords in the open data field. The intellectual structure presented by the KBCA technique with 63 key keywords identified the main areas of open government and open science and 10 sub-areas. On the other hand, the intellectual structure network of co-occurrence word analysis was found to be insufficient in the overall structure and detailed domain structure. This result can be considered because the KBCA sufficiently measures the relationship between keywords using the degree of bibliographic coupling.

An Analysis of Sexuality Education Books for Children and Young Adults (어린이·청소년 대상 성교육 도서의 현황 분석 연구)

  • Lim, Yeojoo
    • Journal of the Korean BIBLIA Society for library and Information Science
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    • v.33 no.1
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    • pp.425-454
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    • 2022
  • This study analyzed the 77 most popular sexuality education books for children and young adults published in Korea, based on various criteria, including subject matters, format, implied readers, and author's occupational background. Among the key topics of the International technical guidance on sexuality education developed by UNESCO, the most mentioned was that it is natural to have curiosity on one's own feelings and body and that sex education books can help them learn about them. Respect on one's own body, knowledge of sexual and reproductive organs, eggs and sperms, menstrual cycle, effect of hormones were also easily found topics from the books. The least mentioned topics were HIV/AIDS and Gender-based violence. 63.5% of the analyzed books were books with/without illustrations. Other formats include picture books, comic books, and photo-illustrated books. Publication of books aimed for particular gender started to increase from 2019. Diversity of authors' occupation were also shown starting 2019. Further research on the role of sex education books is crucial to help all children and young adults develop their own sexuality and understand that of other people, and ultimately to live in a harmonious society.

A Study on the Importance of Improvement Measures for the Revitalization of Urban Regeneration Projects in General Neighborhood in Pyeongtaek City (평택시 일반근린형 도시재생사업 활성화를 위한 개선방안의 중요도에 관한 연구)

  • Kyung-Joo Kang;Jung-Min Jang
    • Land and Housing Review
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    • v.14 no.2
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    • pp.51-71
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    • 2023
  • Based on the challenges encountered in the urban regeneration projects (general neighborhood-type) of Anjung District and Sinjang District in Pyeongtaek City, this study aims to explore the key factors of improvement measures for urban regeneration projects. Using the first survey conducted among shopping mall owners, employees, and residents, this study finds a significant level of awareness and very strong needs for urban regeneration projects. On the other hand, the overall satisfaction levels are observed to be low across the three factors: social, economic, and cultural. The second expert survey and the subsequent Analytic Hierarchy Process (AHP) analysis conducted for improvement measures reveal notable discrepancies in the prioritization of factors between administrative experts and practical experts. For the importance of administrative experts, the establishment of network-type regional governance was ranked first for the importance, followed by hosting events related to the U.S. military and long-term pre-market operations, and expanding exchange and cooperation between the U.S. Forces Korea and the community. For the importance of working-level experts, hosting U.S. military-related events and long-term pre-market operations was ranked first, while supporting U.S. military-related festivals and developing local natural landscape resources was ranked second. Our findings suggest the need for proactive measures such as attracting commercial facilities to stimulate demand from both the U.S. military and local residents, thereby revitalizing general neighborhood-type urban regeneration projects, developing programs for local tourism, and operating pre-market operations in the long run. Therefore, this study highlights the importance of regional government cooperation for urban regeneration projects.

Diagnostic Approach to a Soft Tissue Mass (연부조직 종양의 진단적 접근)

  • Chun, Young Soo;Song, Seung Hyun
    • Journal of the Korean Orthopaedic Association
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    • v.54 no.4
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    • pp.293-301
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    • 2019
  • Soft tissue masses of the extremities and torso are a common problem encountered by orthopaedic surgeons. Although these soft tissue masses are often benign, orthopaedic surgeons need to recognize the key features differentiating benign and malignant masses. An understanding of the epidemiology and clinical presentation of soft tissue masses is needed to develop a practical approach for evaluation and surgical management. Size and depth are the two most important factors on which triage decisions should be based. In a differential diagnosis of a tumor, it is important to know the characteristics of the soft tissue mass through detailed history taking and physical examinations before the diagnostic procedures. A variety of imaging studies, such as simple radiography, ultrasound, magnetic resonance imaging, positron emission tomography, computed tomography, bone scan, and angiography can be used to diagnose tumors. Know the ledge of advantages and disadvantages of each imaging study is essential for confirming the characteristics of the tumor that can be observed in the image. In particular, ultrasonography is convenient because it can be performed easily in an outpatient clinic and its cost is lower than other image studies. On the other hand, the accuracy of the test is affected by the skill of the examiner. A biopsy should be performed to confirm the tumor and be performed after all imaging studies have been done but before the final treatment of soft tissue tumors. When a biopsy is to be performed, careful attention to detail with respect to multidisciplinary coordination beforehand, cautious execution of the procedure to minimize complications, and expedient follow-up and referral to a musculoskeletal oncologist when appropriate, are essential.