• Title/Summary/Keyword: Jeonbuk

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Long-Term Survival Outcomes of Elderly Patients Treated With S-1 or Capecitabine Plus Oxaliplatin for Stage II or III Gastric Cancer: A Multicenter Cohort Study

  • Choi, Seohee;Min, Jae-Seok;Jeong, Sang-Ho;Yoo, Moon-Won;Son, Young-Gil;Oh, Sung Jin;Kim, Jong-Han;Park, Joong-Min;Hur, Hoon;Jee, Ye Seob;Hwang, Sun-Hwi;Jin, Sung-Ho;Lee, Sang Eok;Lee, Young-Joon;Seo, Kyung Won;Park, Sungsoo;Lee, Chang Min;Kim, Chang Hyun;Jeong, In Ho;Lee, Han Hong;Choi, Sung Il;Lee, Sang-Il;Kim, Chan-Young;Chae, Hyundong;Son, Myoung-Won;Pak, Kyung Ho;Kim, Sungsoo;Lee, Moon-Soo;Kim, Hyoung-Il
    • Journal of Gastric Cancer
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    • v.22 no.1
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    • pp.67-77
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    • 2022
  • Purpose: Tegafur/gimeracil/oteracil (S-1) and capecitabine plus oxaliplatin (CAPOX) are standard adjuvant chemotherapies (ACs) administered after gastrectomy to patients with stage II or III gastric cancer. However, the efficacy of AC in elderly patients remains unclear. The objective of this retrospective multicenter cohort study was to compare the efficacies of S-1 and CAPOX AC in patients aged ≥70 years. Materials and Methods: Nine hundred eighty-three patients who were treated with AC using S-1 (768 patients) or CAPOX (215 patients) were enrolled in this study. Each patient underwent AC after curative gastrectomy for stage II or III gastric cancer at one of 27 hospitals in the Republic of Korea between January 2012 and December 2013. Relapse-free survival (RFS) and overall survival (OS) were analyzed according to AC regimen and age group. Results: Of the 983 patients, 254 (25.8%) were elderly. This group had a similar RFS (P=0.099) but significantly poorer OS (p=0.003) compared with the non-elderly group. Subgroup analysis of the non-elderly group revealed no AC-associated differences in survival. Subgroup analysis of the elderly group revealed significantly better survival in the S-1 group than in the CAPOX group (RFS, P<0.001; OS, P<0.001). Multivariate analysis revealed that the CAPOX regimen was an independent poor prognostic factor for RFS (hazard ratio [HR], 1.891; 95% confidence interval [CI], 1.072-3.333; P=0.028) and OS (HR, 2.970; 95% CI, 1.550-5.692; P=0.001). Conclusions: This multicenter observational cohort study found significant differences in RFS and OS between S-1 and CAPOX AC among patients with gastric cancer aged ≥70 years.

ICT-Based Ginseng Process Ginseng Plant Composition Analysis (ICT 기반의 인삼 공정 육묘 시 인삼 식물체 분석)

  • Kim, D.H.;Kim, Y.B.;Koo, H.J.;Baek, H.J.;Lee, S.B.;Hong, E.K.;Kim, S.K.;Chang, K.J.
    • Journal of Practical Agriculture & Fisheries Research
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    • v.23 no.2
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    • pp.63-70
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    • 2021
  • In order to compare and investigate the growth rates of each of the various soils, the soil mixing ratios were varied to four soils (Pitmos, Pearlite, Masato, General Soil, and Cocopeat). Ten were selected for each soil ratio and the average length and weight were compared. As a result, in the ratio of No. 1 pitmos 6.5: Perlite 2: Masato 1.5, it was measured as 16.36cm, 0.60g. In the ratio of No. 2 pitmos 10, 13.74cm, 0.41g. In the ratio of No. 3 general clay 10, it was measured as 12.43cm, 0.26g. 4 general clay 8, 0.39g. The growth rate of each soil was measured to be superior to that of other soil growth environments in the ratio of pitmos 6.5: pearlite 2: masato 1.5 soil. For ginseng plant analysis, 30 ginseng plants grown in the average length and weight of each soil at a ratio of 6.5: pearlite 2: masato 1.5 and relatively low-result general soil were selected and analyzed. As a result, 1,040ppm of nitrite nitrogen(NO3-N) was higher in ginseng plants grown in general soil. There was no significant difference in phosphoric acid(P), potassium(K), and magnesium(Mg). Ginseng is characterized by poor growth when it exceeds 300ppm by combining ammonia tae (NH4-N) and nitrate tae (NO3-N) nitrogen. In addition, nitric acid produced in a part of this nitrite makes the pH reaction of the soil acidic, and the nitrite remaining in the soil evaporates into gas.

A Study on the Rational Improvement of the Regulation and System about Embryo Preservation (배아 보존에 관한 합리적 제도 개선을 위한 연구)

  • Baik, Sujin;Moon, Hannah;Park, Inkyoung;Cha, Seunghyun;Park, Joonseok;Lee, Gyeonghun;Park, Chun-seon;Cho, Heesoo;Kim, Myung-Hee
    • The Korean Society of Law and Medicine
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    • v.22 no.3
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    • pp.57-95
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    • 2021
  • Korea's period for preservation of embryos is up to five years (the Bioethics Act). However, the study reviewed domestic and foreign laws and drew issues due to the recent demand that the development of related science and technology and the period limitation limit the rights of consent holder for embryo production. the first issue is that preserved embryos are intended for pregnancy, and it is important to ensure that the autonomy of the consent holder is protected through careful consideration based on information such as scientific evidence. the second is that regulations regarding the obligation to manage embryonic preservation institutions are needed. the third is to create a social atmosphere in which embryo creation, preservation, and disposal take place in a minimum range, considering the special status of embryos. based on this issue, the first of the proposals for rational improvement of the regulation and system about embryo preservation is the introduction of an environment in which sufficient explanation and appropriate consent can be exercised and to extend the reasons for the extension of the period, rather than specifying the specific period in law. the second is that institutionalization is necessary considering not only the obligation to manage preservation institutions but also the overall site, such as concerns that may arise as a result. lastly, we propose the introduction of a management method considering the future use of embryos, such as transfer to provide research purposes and donation of pregnancy purposes by others. this process should be a method of sufficient social discussion and consensus, as well as a general consideration of the family relationship with the born child.

A Study on Calligraphy theory and the Calligraphy and Paintings aesthetic of GangAm, Song Sungyong (강암(剛菴) 송성용(宋成鏞)의 서예관과 서화미학 고찰)

  • Kim, Doyoung
    • The Journal of the Convergence on Culture Technology
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    • v.7 no.4
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    • pp.273-280
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    • 2021
  • GangAm Song Sungyong (1913~1999) was from Gimje, Jeollabuk-do. And he is a calligrapher from the last Confucian scholar of the 20th century and a writer of poetry, calligraphy, and painting. While wearing a topcoat and hanbok for the rest of his life, he approached the study, thought, and calligraphy art of Yoo Jae Song Kimyeon and Kojae Lee Byungeun from the perspective of 'GucheSinyong'. And he kept the philosophical subjectivity that tries to maintain character and a right mind. It was based on 'Guche', which is a faithful succession to the reverence of the old. When I was young, I practiced Mibul and Dong Kichang with Gu Yangsun as the center, and Hwang Jeonggyeon, Hanye, Oh Heejae, and Sojeon typefaces were grafted together during the national exhibition. Then, in 1965 (age 53), he moved to Jeonju, and learned several typefaces such as Chusa typeface on his own, creating a Gangam typeface without any obstacles. And he created 'Sinyong' with Windy Bamboo painting, which embodied strange and unconventional meanings. In addition, he re-established his identity by reexamining the fundamental spirit and natural aesthetics of calligraphy, and based on this, he greatly contributed to expanding the aesthetics of modern calligraphy and painting art by pursuing an aesthetic that explores novelty. In particular, Windy Bamboo painting has strong abstraction based on the principle of 'drawing the will'. And, in terms of discipline, the ethical aesthetic of Express Tao with pictures (畵以載道), which expresses the high level of elegance of observing small things in a big way, based on deep research on the logic of things and fulfilling human nature. By implementing it, Tao and Art become one. The Jeonbuk calligraphy group achieved the greatest prosperity in the Gangam era, and at the end of the 20th century, it entered a period of revival as it established itself as the central calligraphy group of Korean calligraphy.

Analysis of Rice Blast Outbreaks in Korea through Text Mining (텍스트 마이닝을 통한 우리나라의 벼 도열병 발생 개황 분석)

  • Song, Sungmin;Chung, Hyunjung;Kim, Kwang-Hyung;Kim, Ki-Tae
    • Research in Plant Disease
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    • v.28 no.3
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    • pp.113-121
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    • 2022
  • Rice blast is a major plant disease that occurs worldwide and significantly reduces rice yields. Rice blast disease occurs periodically in Korea, causing significant socio-economic damage due to the unique status of rice as a major staple crop. A disease outbreak prediction system is required for preventing rice blast disease. Epidemiological investigations of disease outbreaks can aid in decision-making for plant disease management. Currently, plant disease prediction and epidemiological investigations are mainly based on quantitatively measurable, structured data such as crop growth and damage, weather, and other environmental factors. On the other hand, text data related to the occurrence of plant diseases are accumulated along with the structured data. However, epidemiological investigations using these unstructured data have not been conducted. The useful information extracted using unstructured data can be used for more effective plant disease management. This study analyzed news articles related to the rice blast disease through text mining to investigate the years and provinces where rice blast disease occurred most in Korea. Moreover, the average temperature, total precipitation, sunshine hours, and supplied rice varieties in the regions were also analyzed. Through these data, it was estimated that the primary causes of the nationwide outbreak in 2020 and the major outbreak in Jeonbuk region in 2021 were meteorological factors. These results obtained through text mining can be combined with deep learning technology to be used as a tool to investigate the epidemiology of rice blast disease in the future.

Improving the Current Status and Cultural Value of Donguibogam Wanyoung Woodblocks (<동의보감(東醫寶鑑)> 완영(完營)책판의 현황과 문화재적 가치 제고(提高))

  • KIM, Hwaseon
    • Korean Journal of Heritage: History & Science
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    • v.55 no.2
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    • pp.50-64
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    • 2022
  • This thesis is a study on the woodblock of Donguibogam by Jeolla Gamyeong(Wanyoung Woodblock). It was registered as a tangible cultural property in Jeollabuk-do in 2005. The purpose of this article is to determine the current status and value of the Donguibogam Wanyoung Woodblock. Jeonju Hyanggyo's Wanyoung Woodblock was used to print books in Gamyeong, Jeolla Province. Currently, ten kinds of woodblocks are preserved. In 1987, a wooden bookshelf was installed and preserved in "Jangpangak" of Jeonju Hyanggyo. It is now preserved and managed at Chonbuk National University Museum. Among the ten woodblocks, the Wanyoung woodblock of Donguibogam is presumed to be a woodblock of a book printed by Jeolla Gamyeong in 1814. The value of Donguibogam has long been recognized domestically and internationally. Donguibogam, compiled in 1610, was first published in 1613 in the wood type of Gaeju Gapinja. Following its publication, its value was recognized not only in Joseon but also in China and Japan. In 2009, the first edition of Donguibogam was registered as a UNESCO World Heritage. Accordingly, Donguibogam has been recognized for various aspects, but little research has been conducted on the woodblocks that printed Donguibogam. Therefore, this paper analyzes the current status of the Wanyoung woodblock of Donguibogam, aiming to enhance its meaning and value. King Seonjo presented the ideals of public health care and preventive medicine when compiling Donguibogam, which was distributed according to his instructions. For this reason, the first edition of Donguibogam was registered as a UNESCO World Heritage. It can be said that the production of Donguibogam woodblocks was an important tool in realizing Joseon's ideals through national dissemination. Furthermore, the woodblock of Donguibogam represents the spirit of thinking about the people, going beyond the purpose of printing, and it was meaningful in the spread of medical knowledge among the people. In this article, I will examine the overall contents of the Wanyoung woodblock of Donguibogam to enhance its meaning and value. The results show that the Wanyoung woodblock of Donguibogam is meaningful in that it is almost the only one produced and stored by Gamyeong. Moreover, Wanyoung woodblocks are meaningful in that perfect editions could be preserved and disseminated for a long time, unlike other wood-type prints.

Quality Changes as Affected by Storage Temperature and Polyamide Film Packaging in Paprika (Capsicum annuum L.) (파프리카 저장 온도 변화와 폴리아미드 필름 포장 적용에 따른 품질 변화)

  • Erdene, Byambaa Bayar;Lee, Jung-Soo;Park, Me Hea;Choi, Ji Won;Eum, Hyang Lan;Malka, Siva Kumar;Yun, Yeoeun;Kim, Chae-Hee;Kim, Ho Cheol;Lee, Jinwook;Park, Ki Young;Bae, Jong Hyang;Lee, YounSuk;Jeong, Cheon Soon;Park, Jong-Suk
    • KOREAN JOURNAL OF PACKAGING SCIENCE & TECHNOLOGY
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    • v.28 no.2
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    • pp.115-125
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    • 2022
  • The purpose of this study was to examine the effect of packaging on quality maintenance of paprika (Capsicum annuum L. cv. Nagano RZ) stored at three different temperatures. In Korea, paprika is stored and distributed under ambient conditions. To ensure the freshness maintenance, determining optimal storage temperature is necessary. Paprika were unpacked (control) or packed with polyamide film and stored at 5℃, 10℃ and 20℃ for 35 days. Quality characteristics such as weight loss and appearance were examined. Paprika packed with polyamide film showed less quality changes compared to unpacked paprika under all the storage temperatures. The commercial properties tended to decrease rapidly during storage at 20℃ regardless of packing. The degree of weight loss was significantly lower in packed paprika compared to unpacked paprika. It was found that soluble solids, pigments, hardness, etc. were complexly affected by storage temperature and film packaging. For paprika, the storage temperature of 5℃ or 10℃ was effective in maintaining freshness; paprika packed in polyamide film packing maintained greater freshness than unpacked paprika. Our results showed that, packaging is required to preserve the freshness and to improve the marketability of paprika in the domestic market. It seems that it is necessary to continuously search for an effective packaging method.

The Impact of Community on Family Relations Satisfaction : Focusing on the Family Happiness Composite Index in Korea (지역사회가 가족관계만족에 미치는 영향 : 한국 가족행복종합지수를 중심으로)

  • Oh, Youngeun;Choo, Joohee;ko, kawangyee
    • 지역과문화
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    • v.7 no.2
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    • pp.173-202
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    • 2020
  • This study aims to enhance the family-friendliness of the region by examining the relationship between family relations and the community environment, and objectively comparing the local environment surrounding the family. To this end, we reviewed the areas of socio-cultural and economic sectors that affect the family relationship satisfaction, and in particular, analyzed the trend of changes in regional index by utilizing the Korean Family Happiness Composite Index (KFHCI) developed as a community indicators. This index utilizes community indicators published in the National Statistical Portal's "e-Region indicators," and these variables are related to family relationship satisfaction. Therefore, this study compared the seven areas of the Family Happiness Composite Index (Population Family, Health Culture, Education, Income Consumption, Employment Labor, Housing Transportation, Environment and Social Integration) by region, and examined the trends for 10 years. According to the study, the average score of KFHCI's entire region was rising from 2008 to 2018. Overall, the community environment that affects family relationship satisfaction is also improving. The regions belonging to the upper level were Jeonnam, Gangwon, Chungnam, Jeonbuk, and Gyeongbuk. Areas belonging to the lower level are Seoul, Busan, Daegu, Incheon, and Gwangju. In almost sectors, the lower-level regions did not have sufficient physical infrastructure compared to population density and over-density, and improved little by little, but not enough to reflect the needs of local people and improve the quality of life. In the future, we should develop more regular and complementary indicators to develop customized policies for each region that can improve the quality of family relationships. It will also be necessary to study the impact of each index field when a socioeconomic crisis occurs due to social disasters, and try to change indicators

An Optimum Summer Cultivation Sowing Date for Seed Production of Oats (Avena sativa L.) (귀리 종자 생산을 위한 여름 재배의 적정 파종 시기 구명)

  • Park, Jin-Cheon;Kim, Yang-Kil;Yoon, Young-Mi;Choi, Su-Yeon;Park, Jong-Ho;Park, Hyoung-Ho;Ra, Kyungyoon;Park, Tae-Il
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.67 no.3
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    • pp.180-188
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    • 2022
  • This study was conducted to determine the optimal sowing date for seed yield of summer oat (Avena sativa L.) cultivars "Darkhorse (DH)" and "Highspeed (HS)" in Wanju, Jeonbuk province between 2017 and 2018. We investigated seed yield from 4 sowing dates: July 15, July 30, August 15, and August 30. We evaluated the agronomic characteristics of summer oats (DH and HS). We found the heading date of all cultivars to be within 50 days. Delayed sowing resulted in significantly increased plant height for both years and cultivars. There was no significant difference in spike length of DH and HS which ranged from 12.8 to 17.8 cm. The sowing date of July 30 produced a higher number of grains per spike, but this yield differed significantly by year and cultivars. In 2017, the first sowing resulted in the lowest DH yield at 132 kg per 10a, while the second sowing had the highest yield at 227 kg. HS yield was the lowest in the first sowing at 126 kg and the highest in the third sowing at 219 kg. In 2018, DH had the lowest yield from the first sowing at 184 kg per 10a, and the highest from the second sowing at 240 kg, but there was no significant difference between these yields. The first sowing for HS gave the lowest yield at 160 kg, and the second sowing produced the highest at 258 kg. The germination rate of harvested seeds from each sowing date in 2017 and 2018 was found to be higher than 85% and there was no significant difference between the two cultivars in the 2018 germination rate test. Thus, we found the optimal sowing date for summer cultivation of oats for the highest seed yield to be between July 30 (second sowing) and August 15 (third sowing).

Growth Characteristics of Tomatoes Grafted with Different Rootstocks Grown in Soil during Winter Season (대목 종류에 따른 저온기 토경재배에서의 토마토 생육 특성 분석)

  • Lee, Hyewon;Lee, Jun Gu;Cho, Myeong Cheoul;Hwang, Indeok;Hong, Kue Hyon;Kwon, Deok Ho;Ahn, Yul Kyun
    • Journal of Bio-Environment Control
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    • v.31 no.3
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    • pp.194-203
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    • 2022
  • Cultivation of tomatoes in Korea grown in soil covers 89% of the total area for tomato cultivation. Tomatoes grown in soil often encounter various environment stresses including not only salt stress and soil-borne diseases but also cold stress in the winter season. This study was conducted to comparatively analyze the performance of rootstocks with cold stress by measuring the growth, yield, and photosynthetic efficiency in tomatoes grown in soil. The rootstocks were used 'Powerguard', 'IT173773', and '20LM' for the domestic rootstock cultivars and 'B-blocking' for a control cultivar. The tomato cultivar 'Red250' was used as the scion and the non-grafted tomatoes. Stem diameter, flowering position, leaf length, and leaf width were investigated for the growth parameters. The stem diameter of the non-grafted tomatoes decreased by 15% compared to the grafted tomatoes at 80 days after transplanting when exposed to low temperatures of 9-14℃ for 14 days. The leaf length and width of the non-grafted tomatoes were the lowest with 42.4 cm and 41.8 cm at 80 days after transplanting. The total yield per plant was the highest in tomato plants grafted on 'Powerguard' with 1,615 g and lowest in non-grafted tomatoes with 1,299 g. As the result of measuring the chlorophyll fluorescence parameters, PIABS and DI0/RC, which mean the performance index and dissipated energy flux, 'Powerguard' was the highest with 3.73 in PIABS and the lowest with 0.34 in DI0/RC, whereas non-grafted tomatoes was the lowest with 2.62 in PIABS and the highest with 0.41 in DI0/RC at 80 days after transplanting. The stem diameter has positive correlation with PIABS, while it has negative correlation with DI0/RC. The results indicate that can be analyzed by chlorophyll fluorescence parameters can be used for analyzing the differences in the growth of tomato plants grafted on different rootstocks when exposed to cold stress.