• 대한간호학회지
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• 제30권4호
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• pp.995-1005
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• 2000

This study was performed to identify the physiological and psychological variables related to successful weaning from a mechanical ventilator. The subjects of this study were 22 patients who received mechanical ventilation therapy for more than 3 days in intensive care units. Before the weaning trial, baseline data for following physiologic variables were obtained: spontaneous respiration rate, blood pressure, pulse rate, PaO2, PaCO2, PEEP, static compliance, minute ventilation, tidal volume, rapid shallow breathing index(f/VT), SaO2, PaO2/FiO2 and mean arterial pressure. During spontaneous breathing, physiologic and psychologic variables such as vital signs, ABG, perspiration, chest retraction, paradoxical respiration, dyspnea, anxiety, confidence and efficacy were measured. Successful weaning was defined as sustaining spontaneous respiration over 24 hours after extubation. Weaning failure was defined as the development of more than one of following signs: (1) hypoxemia, (2) CO2 retention or (3) perspiration, tachypnea, chest retraction, tachycardia, arrhythmia, hypotension or hypertension. Subjects (N=18) who successfully weaned from mechanical ventilator were compared with subjects (N=4) who failed. The results are as follows; Eighteen percents of the subjects failed during the weaning trial. Most subjects in the failed group were mechanically ventilated for long-time. This result shows that the success of weaning is more difficult in long-term ventilation patients. In the baseline data that was measured before weaning trial, the mean score of PaO2 in the successfully weaned group was 121mmHg. This is significantly higher than the mean score of PaO2 in the failed group(95mmHg). However, the scores of pH, tidal volume, f/VT, pulse rates, blood pressure, mean airway pressure, SaO2, and PaCO2 were similar between the two groups. Specially the scores of f/VT index as a predominant predictor for successful weaning were not significant (f/VT=44.4) and (f/VT=47). During spontaneous breathing, the scores of dyspnea and anxiety level in the successfully weaned group were less than those of the failed group. On the contrary, the scores of confidence and efficacy in the successful group were greater than those of the failed group. In conclusion, the baseline data that were measured before weaning trial were similar between the both groups, therefore future studies are needed to focus on searching other variables besides physiological parameters related to weaning outcome.

• Genomics & Informatics
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• 제10권2호
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• pp.99-105
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• 2012

Dyslipidemia, mainly characterized by high triglyceride (TG) and low high-density lipoprotein cholesterol (HDL-C) levels, is an important etiological factor in the development of cardiovascular disease (CVD). Considering the relationship between childhood obesity and CVD risk, it would be worthwhile to evaluate whether previously identified lipid-related variants in adult subjects are associated with lipid variations in a childhood obesity study (n = 482). In an association analysis for 16 genome-wide association study (GWAS)-based candidate loci, we confirmed significant associations of a genetic predisposition to lipoprotein concentrations in a childhood obesity study. Having two loci (rs10503669 at LPL and rs16940212 at LIPC) that showed the strongest association with blood levels of TG and HDL-C, we calculated a genetic risk score (GRS), representing the sum of the risk alleles. It has been observed that increasing GRS is significantly associated with decreased HDL-C (effect size, $-1.13{\pm}0.07$) compared to single nucleotide polymorphism combinations without two risk variants. In addition, a positive correlation was observed between allelic dosage score and risk allele (rs10503669 at LPL) on high TG levels (effect size, $10.89{\pm}0.84$). These two loci yielded consistent associations in our previous meta-analysis. Taken together, our findings demonstrate that the genetic architecture of circulating lipid levels (TG and HDL-C) overlap to a large extent in childhood as well as in adulthood. Post-GWAS functional characterization of these variants is further required to elucidate their pathophysiological roles and biological mechanisms.

• 대한한방내과학회지
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• 제39권1호
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• pp.22-43
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• 2018

Objective: The purpose of this study is to investigate the effect of Cheonmagudeung-eum (CGE) for essential hypertension by systematic review and meta-analysis. Methods: The period of literature search was until October 30, 2016, and 14 electronic databases were utilized as search engines. The evaluation for the risk of bias (RoB) was conducted by using the Cochrane Risk of Bias Tool. The meta-analysis was performed by synthesizing outcome data, including total effective rate (TER), systolic blood pressure (SBP), diastolic blood pressure (DBP), and the incidence of adverse events. Result: There were a total of 64 RCTs using CGE on adult essential hypertension. In the RoB evaluation, most of the items were unclear, and the qualities of studies were rated low. The concurrent treatment of CGE and antihypertensive drug (AHD) showed a significant hypotensive effect since the risk ratio (RR) of TER was 1.17 times (95% CI 1.14, 1.20, p<0.01) higher than that of AHD alone. In addition, the mean difference (MD) appeared low as 8.73 mm/Hg in SBP (95% CI -11.36, -6.09, p<0.01) and 5.81 mm/Hg in DBP (95% CI -7.50, -4.12, p<0.01). Conclusion: Through this study, it was identified that the combined treatment of CGE and AHD on hypertension would be more effective than that of AHD treatment alone. However, due to the low quality of the selected original articles, the significance of this conclusion is somewhat limited, and we hope that this would be complemented through more rigorous RCTs in the future.

• 폴리머
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• 제34권3호
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• pp.191-197
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• 2010

이방성 전도필름(ACF)의 경화방법을 개선하기 위하여 이미다졸계 경화제 대신에 저온에서도 경화가 빠른 열잠재성 양이온 개시제형 경화제를 사용한 에폭시 수지의 경화를 연구하였다. 경화특성의 분석을 위해 유리전이온도, 저장모듈러스, 열팽창계수를 포함한 열적기계적 특성을 조사하였으며 열사이클, 고온고습 신뢰성을 관찰하였다. 열잠재성 양이온 개시제형 경화제를 사용한 ACF가 이미다졸계 경화제를 사용한 경우보다 경화속도는 빨랐으며, 열팽창계수는 낮았고, $T_g$가 높아서 고온안정성도 우수하였다. 또 낮은 온도와 빠른 경화에도 불구하고 안정적인 접속 저항을 유지하여 높은 신뢰성을 나타내었다. 본 연구를 통하여 에폭시 경화방법은 ACF의 열적기계적 특성과 신뢰성에 큰 영향을 미치는 중요한 인자임을 확인하였다.

• 농약과학회지
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• 제20권4호
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• pp.341-348
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• 2016

밀의 재배기간 중 살포된 살균제 fludioxonil 및 metconazole의 부위별 잔류양상을 조사하였다. 밀 부위별 fludioxonil 및 metconazole (cis 및 trans 이성질체의 합)의 잔류분석 회수율은 84.3~113.3%이었으며 변이계수는 0.1~4.7%로 나타나 잔류농약분석 기준을 만족하였다. 두 농약 모두 처리구별 수확된 밀의 짚부위에 가장 많이 잔류되었으며 가식부인 밀알에서 잔류량이 가장 적었다. 밀의 가식부에 잔류하는 농약의 농도는 fludioxonil은 2회 및 3회 살포시 0.01~0.07 mg/kg, metconazole은 0.13~0.17 mg/kg로 나타났다. 침투성 농약인 metconazole은 fludioxonil 보다 더 낮은 농도로 살포되었음에도 불구하고 밀의 가식부로 침투량이 더 많았으며 cis 이성질체가 trans 이성질체 보다 많이 잔류되었다. 밀의 각 부위별 평균무게를 이용하여 밀 한 개체 당 농약의 잔류절대량을 산출하고 밀의 각 부위별 분포율을 산출한 결과, 두 농약 모두 짚 부위에서 68.5~70.7%의 분포율을 나타내었으며 가식부에서 분포율은 0.8% 미만이었다.

• 한국콘텐츠학회논문지
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• 제9권10호
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• pp.482-491
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• 2009

본 연구는 유아기관에서 상용화되어 있는 지능형 로봇 iRobiQ에 탑재할 교사보조 콘텐츠 '우리반'을 기획하고 개발하는 것을 목적으로 하였다. 유아교육기관의 하루일과 중 iRobiQ가 교사보조로서 활용할 수 있는 기능을 추출하여 6개의 기능(출석, 활동, 갤러리, 배움터, 호명, 타이머)을 개발하였다. 유아가 매체를 다룰 때 수행하게 되는 주요 역할인 놀이자, 학습자, 사용자에 따라서 각각 오락적, 학습적, 도구적 요소를 충족시켜야 한다는 PLU 모델에 따라서 역할 모델에 따른 요소들을 기능에 반영하고자 하였다. 특히, 로봇은 정서적인 관계를 수행할 수 있기에 유아는 로봇을 친구(Companion)로서 접근할 수 있으며, 이에 따라서 또래 역할을 수행할 수 있는 정서적 요소들 또한 개발에 반영하였다. 유아기관에서 개발된 '우리반' 콘텐츠의 수용 양상을 살펴보기 위하여 4주간에 걸친 관찰을 수행한 결과, 교사와 유아 모두에게 긍정적인 반응을 얻었으며, 특히 유아의 경우에는 오락적, 정서적 요소에 더 많은 반응을 하였고, 로봇의 사용 방식이 점차 고정되는 교사와 달리 유아들은 끊임없이 새로운 요소를 탐색하였다. 개발 결과와 더불어서 향후 로봇 교사보조 콘텐츠를 개발할 때 고려해야 할 사항들을 논의한다.

• 한방안이비인후피부과학회지
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• 제29권4호
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• pp.14-23
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• 2016

Objectives : One of major complications of diabetes, diabetic ulcer is also one of the main reasons for amputation, and the prevalence rate is 4-10%. Laser therapy is widely used for leg ulcer and diabetic ulcer, and it is known to improve wound epithelialization, cellular content, and collagen deposition. The purpose of this study is to investigate the properties of the laser and the spectrum of laser instruments for diabetic ulcer. Methods : We performed literature search using the PubMed, Cochrane, CINAHL and Web of science for the data in English. In addition, other databases were checked for different languages such as OASIS and NDSL for the literature in Korean, CNKI in Chinese, and CiNii and J-STAGE written in Japanese. We excluded all review article and experimental studies, and only clinical studies using laser or light emitting diode (LED) for diabetic ulcer were selected. Results : A total twenty papers were selected. Different light sources were used as follows: LED, HeNe, InGaAlP, GaAlAs, GaAs, CO2, and KTP. The number of LED studies was 9, and HeNe laser was 7, and InGaAlP and GaAlAs laser was 2, GaAs, CO2, and KTP laser was 1 for each. Various energy density of the clinical study were reported. Conclusions : It is suggested that to select appropriate laser type and give the adequate output power to treat diabetic ulcer. Further evaluation and research for the condition of laser therapy to treat diabetic ulcers are warranted.

• 임상간호연구
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• 제26권1호
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• pp.117-130
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• 2020

Purpose: This study aimed to develop a bedside nursing shift report protocol and evaluate the effect of the protocol in a tertiary hospital in South Korea. Methods: The bedside nursing handoff protocol with patient engagement was developed based on the literature review and the validation of an expert group. The effect of the protocol on clinical implication was tested in three medical-surgical units in a tertiary hospital. Outcomes were assessed by patient perception, nurse perception, and reporting time. Data collected from June to August in 2018 and analyzed with descriptive statistics and One-way ANOVA using SPSS version 25.0. Results: The bedside nursing shift report protocol with patient engagement consisted of two steps: nurse to nurse report and bedside report with patients. Nurse's perception with patient engagement was significantly increased after applying protocol (F=17.85, p<.001). Patient's perception was significantly improved in the areas of discharge plan (F=7.86, p<.001), health information privacy (F=4.46, p=.012) and identify attending nurse (F=3.19, p=.042). There were no differences in reporting time between the bedside nursing shift report and a traditional shift report (F=0.61, p=.054). Conclusion: Patient perception was significantly increased, while nurse perception was not different after applying this protocol. For the change in the perception of nurses, education may be preceded to improve nurses' competence for the bedside shift report. Furthermore, the support in enough nurse staffing should be needed for encouraging the bedside shift report. The bedside shift report may enhance patient engagement. Therefore it may improve patient safety and health outcome in clinics.

• 임상간호연구
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• 제25권2호
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• pp.120-132
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• 2019

Purpose: This study aimed to investigate the performance of patient engagement nursing services perceived by nurses and necessity in Korea. Methods: This study was a descriptive research. A total of 205 nurses participated in the study. The Smart Patient Engagement Assessment Checklist was developed by the investigators to assess patient engagement nursing services performance and necessity. The data were collected using online survey. Descriptive analysis and $x^2$ analysis were performed using SPSS 25.0 program. Results: The mean age of participants was $36.6{\pm}8.5years$ and the mean working experience was $12.92{\pm}9.23years$. Seventy eight percent of participants reported that patients and family participated in care as advisors through customer's suggestion or patient satisfaction assessment. The rate of patients' and family's engagement in care as advisors was significantly higher in tertiary hospitals ($x^2=28.54$, p<.001). About 89% of participants communicated with patients and family to make clinical decisions with a multidisciplinary approach. The rate of communication for multidisciplinary decision making was significantly higher in tertiary hospitals ($x^2=6.30$, p=.012). With regards to nurses' bedside patient handoff, 22.0% of participants reported that they were performing bedside patient handoff, and there was no significant difference between type of hospitals. About discharge planning, 72.2% of participants reported utilizing discharge checklist. Conclusion: Currently, patient engagement nursing services are applied partially in Korea. It seems that care protocols to be applied for patient engagement nursing services are insufficient. Therefore, patient engagement care protocols need to be developed to improve patient's health outcome and safety.

• 산업융합연구
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• 제21권8호
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• pp.75-86
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• 2023

본 연구는 고등학생의 공동체의식, 시민의식, 진로정체성과 행복감의 영향 관계에서 진로정체성의 매개효과를 검증하여 행복감을 높이기 위한 기초자료를 제공하는데 목적이 있다. 자료분석은 한국청소년정책연구원에서 조사한 '2020년 Z세대 10대 청소년 가치관 조사' 데이터를 사용하였다. 조사대상자 중 본 연구목적에 부합하는 고등학생 3,037명 중 결측을 제외한 2,959명을 표본으로 추출하여 SPSS WIN 23.0 프로그램을 활용하여 분석하였다. 분석방법은 빈도분석, 기술통계분석, 상관분석 및 베이런과 케니의 분석방법을 활용하여 매개효과를 검증하고 Sobel test 기법을 적용하여 간접효과와 유의성을 분석하였다. 연구결과는 첫째, 고등학생의 공동체의식과 시민의식이 행복감을 높여주었다. 둘째, 공동체의식과 행복감과의 관계에서 진로정체성은 부분 매개효과가 나타났다. 셋째, 시민의식과 행복감과의 관계에서 진로정체성의 부분 매개효과를 보여주고 있다. 이를 토대로 본 연구에서는 고등학생의 행복감 증진을 위한 정책적 대안과 실천적 프로그램을 제시하였다는 점에서 의의를 갖는다.