• Title/Summary/Keyword: Interval Censored Data

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Analyzing Clustered and Interval-Censored Data based on the Semiparametric Frailty Model

  • Kim, Jin-Heum;Kim, Youn-Nam
    • The Korean Journal of Applied Statistics
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    • v.25 no.5
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    • pp.707-718
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    • 2012
  • We propose a semi-parametric model to analyze clustered and interval-censored data; in addition, we plugged-in a gamma frailty to the model to measure the association of members within the same cluster. We propose an estimation procedure based on EM algorithm. Simulation results showed that our estimation procedure may result in unbiased estimates. The standard error is smaller than expected and provides conservative results to estimate the coverage rate; however, this trend gradually disappeared as the number of members in the same cluster increased. In addition, our proposed method was illustrated with data taken from diabetic retinopathy studies to evaluate the effectiveness of laser photocoagulation in delaying or preventing the onset of blindness in individuals with diabetic retinopathy.

Effects of Informative Censoring in the Proportional Hazards Model (비례위험모형에서 정보적 중도절단의 효과)

  • 정대현;홍승만;원동유
    • Journal of Applied Reliability
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    • v.2 no.2
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    • pp.121-133
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    • 2002
  • This paper concerns informative censoring and some of the difficulties it creates in analysis of survival data. For analyzing censored data, misclassification of informative censoring into random censoring is often unavoidable. It is worthwhile to investigate the impact of neglecting informative censoring on the estimation of the parameters of the proportional hazards model. The proposed model includes a primary failure which can be censored informatively or randomly and a followup failure which may be censored randomly. Simulation shows that the loss is about 30% with regard to the confidence interval if we neglect the informative censoring.

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A semiparametric method to measure predictive accuracy of covariates for doubly censored survival outcomes

  • Han, Seungbong;Lee, JungBok
    • Communications for Statistical Applications and Methods
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    • v.23 no.4
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    • pp.343-353
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    • 2016
  • In doubly-censored data, an originating event time and a terminating event time are interval-censored. In certain analyses of such data, a researcher might be interested in the elapsed time between the originating and terminating events as well as regression modeling with risk factors. Therefore, in this study, we introduce a model evaluation method to measure the predictive ability of a model based on negative predictive values. We use a semiparametric estimate of the predictive accuracy to provide a simple and flexible method for model evaluation of doubly-censored survival outcomes. Additionally, we used simulation studies and tested data from a prostate cancer trial to illustrate the practical advantages of our approach. We believe that this method could be widely used to build prediction models or nomograms.

Reliability for Series System in Bivariate Weibull Model under Bivariate Type I Censorship

  • Cho, Jang-Sik;Cho, Kil-Ho
    • Journal of the Korean Data and Information Science Society
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    • v.14 no.3
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    • pp.571-578
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    • 2003
  • In this paper, we consider two components system which have bivariate weibull model with bivariate type I censored data. We proposed maximum likelihood estimator and relative frequency estimator for the reliability of series system. Also, we construct approximate confidence intervals for the reliability based on the two proposed estimators. And we present a numerical study.

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Parameters Estimators for the Generalized Exponential Distribution

  • Abuammoh, A.;Sarhan, A.M.
    • International Journal of Reliability and Applications
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    • v.8 no.1
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    • pp.17-25
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    • 2007
  • Maximum likelihood method is utilized to estimate the two parameters of generalized exponential distribution based on grouped and censored data. This method does not give closed form for the estimates, thus numerical procedure is used. Reliability measures for the generalized exponential distribution are calculated. Testing the goodness of fit for the exponential distribution against the generalized exponential distribution is discussed. Relevant reliability measures of the generalized exponential distributions are also evaluated. A set of real data is employed to illustrate the results given in this paper.

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Logistic Regression Method in Interval-Censored Data

  • Yun, Eun-Young;Kim, Jin-Mi;Ki, Choong-Rak
    • The Korean Journal of Applied Statistics
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    • v.24 no.5
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    • pp.871-881
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    • 2011
  • In this paper we propose a logistic regression method to estimate the survival function and the median survival time in interval-censored data. The proposed method is motivated by the data augmentation technique with no sacrifice in augmenting data. In addition, we develop a cross validation criterion to determine the size of data augmentation. We compare the proposed estimator with other existing methods such as the parametric method, the single point imputation method, and the nonparametric maximum likelihood estimator through extensive numerical studies to show that the proposed estimator performs better than others in the sense of the mean squared error. An illustrative example based on a real data set is given.

Analysis of recurrent event data with incomplete observation gaps using piecewise models

  • Kim, Yang-Jin
    • Journal of the Korean Data and Information Science Society
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    • v.25 no.5
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    • pp.1117-1125
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    • 2014
  • In a longitudinal study, subjects can experience same type of events repeatedly. Also, there may exist intermittent dropouts resulting in repeated observation gaps during which no recurrent events are observed. Furthermore, when such observation gaps have incomplete forms caused by the unknown termination times of observation gaps, ordinary approaches result in biased estimates. In this study, we investigate the effect of ignoring observation gaps and propose methods to overcome this problem. For estimating the distribution of unknown termination times, an interval-censored mechanism is applied and two cases are considered. Simulation studies are carried out to evaluate the performance of the proposed method. Conviction data of young drivers with several suspensions are analyzed to illustrate the suggested approach.

Estimation for the extreme value distribution under progressive Type-I interval censoring

  • Nam, Sol-Ji;Kang, Suk-Bok
    • Journal of the Korean Data and Information Science Society
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    • v.25 no.3
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    • pp.643-653
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    • 2014
  • In this paper, we propose some estimators for the extreme value distribution based on the interval method and mid-point approximation method from the progressive Type-I interval censored sample. Because log-likelihood function is a non-linear function, we use a Taylor series expansion to derive approximate likelihood equations. We compare the proposed estimators in terms of the mean squared error by using the Monte Carlo simulation.

Two-Sample Inference for Quantiles Based on Bootstrap for Censored Survival Data

  • Kim, Ji-Hyun
    • Journal of the Korean Statistical Society
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    • v.22 no.2
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    • pp.159-169
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    • 1993
  • In this article, we consider two sample problem with randomly right censored data. We propse two-sample confidence intervals for the difference in medians or any quantiles, based on bootstrap. The bootstrap version of two-sample confidence intervals proposed in this article is simple to apply and do not need the assumption of the shift model, so that for the non-shift model, the density estimation is not necessary, which is an attractive feature in small to moderate sized sample case.

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Bayesian Prediction Inference for Censored Pareto Model

  • Ko, Jeong-Hwan;Kim, Young-Hoon
    • Journal of the Korean Data and Information Science Society
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    • v.10 no.1
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    • pp.147-154
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    • 1999
  • Using a noninformative prior and an inverted gamma prior, the Bayesian predictive density and the prediction intervals for a future observation or the p - th order statistic of n' future observations from the censord Pareto model have been obtained. In additions, numerical examples are given in order to illustrate the proposed predictive procedure.

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