• Reproductive and Developmental Biology
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• 제34권1호
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• pp.27-32
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• 2010

This study was conducted to estimate the effect of the breed, sire-breeds, farrowing year, farrowing season and parity on number of born alive (NBA), number of weaning (NW) and survival rates of weaning (SRW) in swine. The data were obtained from 46,704 litters of the Landrace, Yorkshire, Duroc and Cross breed farrowed from 1996 to 2005 at 142 GP are registered in Korean Animal Improvement Association (KAIA). There was highly significant effect of breed, sire breed, farrowing year, farrowing season and parity on NBA, NW, SRW (p<0.01). The result of this study could be available to genetic improvement of reproductive traits as a basic reference in Korean pig industry. To achieve the more effective improvement of reproductive traits, additional research such as genetic parameter evaluation should be performed.

• 성인간호학회지
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• 제29권2호
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• pp.177-189
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• 2017

Purpose: A meta-analysis was conducted to identify the effect of cognitive improvement programs for the elderly with mild cognitive impairment (MCI) in Korea. Methods: Five databases, as well as relevant reference lists, of studies published from 2000 to 2016, were searched. Fourteen studies were identified. Quality assessments of included studies were conducted using the Scottish Intercollegiate Guidelines Network checklist. An R program was used to analyze effect sizes and to identify possible sources of heterogeneity among studies. The potential for publication bias was investigated using a funnel plot, Egger's regression test and sensitivity analysis. Results: The total effect size was large (Standardized Mean Difference [SMD]=1.44, 95% CI: 1.11~1.77), with cognition based intervention (SMD= 1.77, 95% CI: 1.26~2.29) and exercise intervention (SMD=1.13, 95% CI: 0.82~1.44). Statistically significant moderators were identified intervention type by meta-ANOVA analyses. Finally, no significant evidence of publication bias was found. Conclusion: There is clear evidence that cognitive improvement programs can greatly enhance cognition in elderly with MCI. Future research should examine the effects of non-pharmacological interventions targeting elderly populations with mild-to-severe cognitive impairment in order to develop and enhance the effectiveness of cognitive improvement programs in Korea.

• Animal cells and systems
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• 제14권4호
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• pp.283-289
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• 2010

Ssanghwa-tang (SHT) is a traditional Korean herbal medicine widely prescribed to decrease fatigue following an illness. The purpose of this study was to investigate the effects of SHT on osteoclast differentiation in vitro, and on bone loss in ovariectomized (OVX) rats in vivo. SHT significantly reduced the receptor activator for the nuclear factor ${\kappa}B$ (NF-${\kappa}B$) ligand (RANKL)-induced tartrate-resistant acid phosphatase (TRAP) activity, and multinucleated osteoclast formation in RAW264.7 cells without affecting cell viability. In addition, SHT significantly attenuated RANKL-induced mRNA expression levels of c-Src and cathepsin K. To examine the in vivo effect of SHT on OVX-induced bone loss in OVX rats, we administered SHT (0.6 g/kg BID) orally to OVX rats for 12 weeks. SHT administration significantly blocked OVX-induced decrease of femoral bone mineral density (BMD) and femoral trabeculae in OVX rats. In conclusion, these results suggest that SHT treatment effectively prevents OVX-induced bone loss, and this effect may result from its inhibitory effect on osteoclast differentiation.

• 농촌계획
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• 제23권4호
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• pp.75-90
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• 2017

The study was intended to identify the effect of the rural development projects (comprehensive improvement of the seats of Eup and Myeon and regional unit comprehensive development projects) on the quality of life in rural areas against local residents living in areas subject to those projects by means of structural equation modeling based on covariance structure analysis. The result indicated that perception factors affecting the quality of life for residents in rural areas by the projects included 'improvement in spatial environment', 'increase in vitality of rural areas', and 'promotion of community activities.' It was also suggested that 'improvement in spatial environment' and 'increase in vitality of rural areas' have significantly positive effect on the quality of life for residents in rural areas while the former has relatively higher correlation. In comparison between comprehensive improvement of the seats of Eup and Myeon and regional unit comprehensive development projects, it was analyzed that all the perception factors of the comprehensive improvement of the seats of Eup and Myeon have effect on the quality of life for residents in rural areas indicating that comprehensive improvement of the seats of Eup and Myeon is more effective than regional unit comprehensive development projects in promoting the community activities. It means that existing rural development projects have been promoted to improve spatial environment rather than improving the quality of life for residents in rural areas. Thus, it is considered that the rural development projects in future should seek for a sense of community so that they can induce voluntary participation by local residents.

• The Journal of Korean Physical Therapy
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• 제26권5호
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• pp.331-343
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• 2014

Purpose: The purpose of this study is to assess the effectiveness of short-wave therapy (SWT) for treatment of knee osteoarthritis (OA) as compared to placebo and control, and to assess the question of whether the effects are related to the mode, dosage, and application method. Methods: We searched randomized, placebo-controlled trials using electronic databases. We also manually reviewed sources in order to identify additional relevant studies. Results: Eight studies (597 participants) with OA were included in the meta-analysis. Pulse SWT had a significant effect on pain relief compared with control treatment, while did not favour compared with the placebo group. Pulse SWT had a significant effect on functional improvement compared with control and placebo treatment. Continuous SWT had no effect on pain relief and functional improvement. Capacitive SWT a significant effect on pain relief, functional improvement, and muscle strength. Continuous and capacitive SWT had increased muscle strength significantly. We found no clinical significance of all outcomes except pain and functional improvement in pulsed SWT with low dose. There was no difference in adverse events. None of the participants experienced any serious adverse events. Conclusion: Low dose pulsed SWT provided a short-term clinical benefit for pain relief and functional improvement. Pulsed SWD with low and high dose had effects on pain and function. There seems to be a placebo effect. We found significant effects on pain and function in capacitive SWT. Despite some positive findings, this analysis lacked data on how effectiveness is affected by mode, dosage, and application method of SWT. Further well-designed clinical studies are required in order to confirm the effectiveness of SWT.

• 품질경영학회지
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• 제48권1호
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• pp.149-169
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• 2020

Purpose: This study analyzes the characteristics of the Quality Management performed by SMEs in the Defense Industry in supply chains and analyzes the effect of the continuous improvement activities based on cooperation. Especially, for Military Supplies, the suitability of products is usually decided by judging their conformity to the specification, and from this structural characteristic, this study would analyze the structural relationship of systematic improvement activities with Supply Chain Quality Management(SCQM) and Business Performance(BP). Methods: Continuous improvement activities(CI) have significance as the driver force for the promotion of Quality Management. Thus, this study analyzed the causal relationships from the perspective of the process among CI, SCQM and BP. For an analysis of the structural characteristics and causal relationships among the constituents, AMOS was used, and 297 companies in the Defense Industry were utilized as samples. Results: It turned out that CI had significant impacts on Management Infra(MGT_Infra), Process Management(PM), Human Resources Management(HRM) and Communication(COMU) and had an indirect impact on the enterprises' financial performance through the parameters of HRM and Communication. Meanwhile, it turned out that between CI and non-financial performance, there was a direct effect, and there was also an indirect effect through the variables of the Management Infra and Communication. Conclusion: It turned out that CI had a positive effect on SCQM as a proactive driver and that they had significant relationships with BP(financial, Non-financial), both financial performance and non-financial performance. However, PM did not have a significant relationship of effect with BP because of the character appearing by the evaluation method of military supplies for the conformity to the specifications.

• 대한본초학회지
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• 제32권3호
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• pp.9-17
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• 2017

Objectives : Kyeongok-go has the effect of antioxidant, anti-cancer, improving fatigue, and hyperlipidemia, but it is not easy to use in clinical practice becausee of the complicated manufacturing process of heat control and moisture control. The aim of this study was to explore the lipid improvement effect of new manufacturing methods prodeced Kyeongok-go in hyperlipidemia rats. Methods : The SD rats were divided randomly into 8 groups of six animals each : Normal rats (Nor), hyperlipidemia rats (Con), hyperlipidemia rats treated with Spirulina 60 mg/kg(SP60), hyperlipidemia rats treated with Commercial Kyeongok-go 1 g/kg (K0), hyperlipidemia rats treated with Kyeongok-go manufactured by heating mantle 1 g/kg (K1), hyperlipidemia rats treated with ginseng fermentation Kyeongok-go 1 g/kg (KF), hyperlipidemia rats treated with Kyeongok-go with black ginseng 1 g/kg (BK), hyperlipidemia rats treated with black ginseng fermentation Kyeongok-go 1 g/kg (BKF). The experimental group induced hyperlipidemia by eating high cholesterol diet for 8 weeks. Also, we compared Kyeongok-go manufacturing method using the new method compared with traditional method. Results : As a result, the improvement effect of hyperlipemia using the new method showed the similar or better improvement effect compared with the conventional method, and it is considered that the Kyeongok-go manufacturing method using the new method can be substituted for the traditional Kyeongok-go manufacturing method. Conclusion : In conclusion, these results suggest that new manufacturing methods prodeced Kyeongok-go has the potential as a anti-hyperlipidemia material which possess lipid improvement activities.

• 한국지반공학회논문집
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• 제26권8호
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• pp.59-66
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• 2010

본 연구에서는 동다짐 공법을 적용할 시 개량심도와 진동영향 예측을 유한요소해석을 통해 그 적용성을 규명하였다. 동다짐 공법이 적용된 기존 현장 조건에 따라 지반을 모델링하였으며, 동적하중 모델은 rigid body force를 적용하였다. 개량심도는 심도별 최대 연직 입자 가속도로 예측을 하여 기존 경험식과 비교 분석하였으며, 진동영향은 진동원으로부터 거리별 연직 최대 입자 속도를 도출하여 기존 경험식에 의한 값과 비교 분석하였다. 수치해석 결과, 개량심도의 경우 기존의 경험식과 비슷한 양상을 띄고 있으며, 진동영향의 경우는 기존 식과 특정 구간에서 차이를 보이고 있으나, 어느 정도 소요이격거리를 예측 할 수 있었다. 이들 해석결과는 경험적인 방법과 더불어 동다짐 설계의 신뢰도 향상을 위한 기초적인 자료가 될 것으로 보인다.

• 산업진흥연구
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• 제8권1호
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• pp.47-53
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• 2023

본 연구는 중소 제조업체의 친환경적 경영활동이 직무향상에 미치는 실증 연구로서 친환경 경영의 현황을 파악하고자 중소기업 제조업체를 대상으로 설문지 총 128개를 분석하였다. 분석결과를 요약하면 다음과 같다. 첫째. 중소기업의 친환경적 경영활동 중 사회적 활동은 직무향상에 통계적으로 유의한 영향을 미치지 못한 것으로 분석되었고, 둘째. 환경적 활동은 업무생산성에 𝛽= .394(p<.001)로 유의미한 영향을 미치는 것으로 나타났고, 직무만족에서는 𝛽=.216, p<.05로 낮은 인과관계를 보이며, 셋째. 경제적 경영활동은 직무만족에서 𝛽= .388(p<.001)로 유의한 영향을 미친 것으로 나타났다. 또한, 업무생 산성에는 β= .267(p<.01)로 낮은 인과관계를 확인하였다. 따라서 직무향상에 미치는 영향 중 업무생산성은 환경적 활동이, 직무만족은 경제적 경영활동이 직무향상에 영향을 미치는 것을 알 수 있었다. 본 연구는 중소기업의 친환경적 경영활동을 위한 환경조성과 경쟁력 있는 전략적 방향 제시 및 연구의 기초자료 제공에 의미가 있다.

• Journal of Preventive Medicine and Public Health
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• 제32권4호
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• pp.427-434
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• 1999

Objectives: This study was conducted to determine, by reviewing the literature, whether treatment of Helicobacter pylori infection in patients with non-ulcer dyspepsia affects symptoms. Methods: We retrieved the literature using MEDLINE search, with nonulcer dyspepsia and Hericobacter pylori and treatment as key words, which were reported from 1984 to 1998, and manual literature search. The criteria for inclusion was as follows; 1) The paper should have confirmed nonulcer dyspepsia as case definition. 2) The paper should have peformed a randomized, blind trial. 3) Confirmation of Helicobacter pylori eradication should be done 4 weeks after treatment. 4) studies with no information on measurement of symptoms after treatment were not accepted. The percentage of patients with symptom improvement after eradication therapy for Helicobacter pylori infection was calculated. Cumulative odds ratio was compared by fixed effect model and random effect model as sensitivity and funnel plot was used to evaluate publication bias. Results: The overall effect size of symptom improvement was calculated by cumulative odds ratio. Cumulative odds ratio of random effect model was 4.16(95% CI: 1.55-11.19). Before integrating each effect sizes into common effect size, the homogeneity test was conducted and random effect model was selected(Cochran's Q=41.08 (d.f=10, p<0.001)). The heterogeneity across studies was evaluated and the different methodological aspects of studies led to differences between study results Conclusions: The results suggest that the eradication of Helicobacter pylori in patients with non-ulcer dyspepsia results more symptom improvement. In studios that shows the opposite results there are methodological aspects explaining the heterogeneity.