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Efficacy of Pulsatile Hemodialyzer to Experimental Renal Failure in Dog (실험적으로 신부전을 유발시킨 개에서 박동형 혈액투석기의 효능)

  • Ji, Hye-Jung;Yun, Young-Min;Lee, Joo-Myoung;Kang, Tae-Young;Kim, Jae-Hoon;Cheong, Jong-Tae;Choi, Min-Joo;Min, Byung-Goo;Lee, Kyoung-Kap
    • Journal of Veterinary Clinics
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    • v.23 no.3
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    • pp.320-324
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    • 2006
  • The purpose of the present study was to compare pulsatile type(Twin Pulse Life Support; TPLS) with rotary type hemodialyzer(AK95) in order to reduce the dialysis time and to improve dialysis effect. Three healthy dogs(about 30 kg BW) were used. Experimental renal failure was induced by the ligation of bilateral renal artery. A pair of catheters were implanted in jugular vein for dialysis. Daily investigated parameters included clinical signs such as vomiting, fecal appearance and activity, and also laboratory data such as PCV, TP, BUN and creatinine. Hemodialysis was started above 90 mg/100 ml BUN level and, laboratory data were measured every an hour for 4 hours. Heparin was administered 300 IU/Kg before dialysis and 150 IU/Kg via IV route every 90 minutes during dialysis. Clinical signs after induction renal failure were shown severe vomiting, anorexia, diarrhea, mucous feces, ataxia, dilated pupil and episcleral hyperemia. The average of BUN value decreased hourly $99{\pm}12.1,\;84{\pm}12.2,\;72{\pm}8.0,\;58{\pm}7.1,\;48{\pm}5.2,\;and\;39{\pm}3.2mg/100ml$ by hemodialysis. The average of creatinine value decreased $7.8{\pm}0.61,\;6.4{\pm}0.40,\;5.3{\pm}0.42,\;4.5{\pm}0.23,\;4.0{\pm}0.41,\;and\;3.4{\pm}0.42mg/100ml$ according to hemodialysis an hour. There are not significantly differences BUN, creatinine, PCV and TP values between pulsatile and rotary type hemodialysis. These results suggested that effects of hemodialysis with Pulsatile type(TPLS) are not significantly difference as compared with hemodialysis of rotary type(AK95). Further research is needed in order to estimate the influence of cardiovascular and pulmonary system in hemodialysis of pulsatile type.

A Study on the Applicability of GSTAR-1D to the Riverbed-Level Variation in the Geum River (GSTAR-1D 모형의 금강 하상변동예측 적용성에 관한 연구)

  • Chung, Sung-Young;Park, Bong-Jin;Jung, Kwan-Sue
    • Proceedings of the Korea Water Resources Association Conference
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    • 2006.05a
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    • pp.1611-1615
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    • 2006
  • The purpose of this study is to simulate the riverbed profile changes downstream of Daecheong re-regulation dam from 1988 to 2001, to evaluate the model's applicability and to predict a long-term riverbed-level variation between 2002 and 2017. As a result of simulation 14 sediment transport equations provided by GSTAR-1D, it was found that Acker's & White formula was the most stable relatively. The interval used to calculate its stability was 7 days for bankful discharge$(1,000m^2/s)$, 3 days for daily maximum flow$(4,273m^2/s)$, 1 day for hourly maximum flow$(7,605m^2/s)$ and minimum flow$(8.5m^2/s)$. The simulation results of river bed changes were evaluated and compared to its measure data from 1988 to 2001. It was showed that there was the degradation for a section between Daecheong re-regulation dam and Maepo water stage gage station due to bed-material, and the degradation for a reach between Maepo and Gongju water stage gage station due to massive aggregate collection. Also, as a result of simulating the river profile change for 2002 to 2017, it was predicted that the section between Daecheong re-regulation dam and Geumnam Bridge would remain as the present profile and the reach between Maepo and Gongju water stage gage station would have some degradations in several parts, which would be stable as a whole unless it was due to artificial river profile change.

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Uncertainty Assessment of Single Event Rainfall-Runoff Model Using Bayesian Model (Bayesian 모형을 이용한 단일사상 강우-유출 모형의 불확실성 분석)

  • Kwon, Hyun-Han;Kim, Jang-Gyeong;Lee, Jong-Seok;Na, Bong-Kil
    • Journal of Korea Water Resources Association
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    • v.45 no.5
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    • pp.505-516
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    • 2012
  • The study applies a hydrologic simulation model, HEC-1 developed by Hydrologic Engineering Center to Daecheong dam watershed for modeling hourly inflows of Daecheong dam. Although the HEC-1 model provides an automatic optimization technique for some of the parameters, the built-in optimization model is not sufficient in estimating reliable parameters. In particular, the optimization model often fails to estimate the parameters when a large number of parameters exist. In this regard, a main objective of this study is to develop Bayesian Markov Chain Monte Carlo simulation based HEC-1 model (BHEC-1). The Clark IUH method for transformation of precipitation excess to runoff and the soil conservation service runoff curve method for abstractions were used in Bayesian Monte Carlo simulation. Simulations of runoff at the Daecheong station in the HEC-1 model under Bayesian optimization scheme allow the posterior probability distributions of the hydrograph thus providing uncertainties in rainfall-runoff process. The proposed model showed a powerful performance in terms of estimating model parameters and deriving full uncertainties so that the model can be applied to various hydrologic problems such as frequency curve derivation, dam risk analysis and climate change study.

Comparison of Annual Maximum Rainfall Series and Annual Maximum Independent Rainfall Event Series (연최대치 계열과 연최대치 독립 호우사상 계열의 비교)

  • Yoo, Chul-Sang;Park, Cheol-Soon
    • Journal of Korea Water Resources Association
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    • v.45 no.5
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    • pp.431-444
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    • 2012
  • This study investigated the differences between annual maximum series and annual maximum independent rainfall event series with relatively short and long rainfall durations. Annual maximum independent rainfall events were selected by applying various IETDs and thresholds to the hourly rainfall data in Seoul for the duration from 1961 to 2010. Annual maximum independent rainfall event series decided were then compared with the conventional annual maximum series. Summarizing the results is as follows. First, the effect of IETD and threshold was not beyond the expected level. For example, as the IETD increases, the frequencies of independent rainfall events decreased similarly in their rate for both with short and long durations. However, as the threshold increases, the frequency of those with rather long durations decreased much higher. Second, The mean rainfall intensity of the independent rainfall events was found to remain constant regardless of their duration. This indicates that the annual maximum rainfall intensity could be found in a rainfall event with longer durations. Lastly, the difference between the annual maximum rainfall series and the annual maximum independent rainfall event series with rather short rainfall durations was found significantly large, which decreases with longer durations. This result indicates that the conventional data analysis method, especially for small basins with short concentration time, could lead an unrealistic design rainfall with little possibility of occurrence.

Estimation of Annual Runway Capacity for Jeju International Airport Considering Aircraft Delays (항공기 지연시간을 고려한 제주국제공항 활주로 연간용량 산정)

  • Park, Jisuk;Yun, Seokjae;Lee, Youngjong;Baik, Hojong
    • Journal of Korean Society of Transportation
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    • v.33 no.2
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    • pp.214-222
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    • 2015
  • Jeju International Airport has become the most delayed airport in Korea, due to increased demand in air passengers and unexpected local weather condition. Observing the demands continuously grow for a decade, the airport is expected to be saturated in the near future. As a part of effort to prepare effective and timely measure for this expected situation, airport planners seeks the annual runway capacity, i.e., the appropriate number of flight operations in a given year with tolerable delay. In practice, the FAA formula is frequently adopted for the capacity estimation. The method, however, has intrinsic issues: 1) the hourly capacity imbedded in the formula is not clearly defined and thus the estimated value is vulnerable to be subjective judgement, and 2) the formula doesn't consider aircraft delay resulted from runway congestion. In this paper, we explain a novel method for estimating the daily runway capacity and then converting to the annual capacity taking into account the aircraft delay. In this paper, average delay of aircraft was measured using microscopic air traffic simulation model. Daily capacity of the runways were analyzed based on the simulation outputs and the method to assess the yearly capacity is introduced. Using a microscopic simulation model named TAAM, we measure the average aircraft delay at various levels of flight demand, and then estimate the practical daily runway capacity. The estimated daily and annual runway capacities of Jeju airport are about 460 operations a day which is equal to 169,000 operations year. The paper discusses how to verify the simulation model, and also suggests potential enhancement of the method.

An Experimental Analysis of a Probabilistic DDHV Estimation Model (확률적인 중방향 설계시간 교통량 산정 모형에 관한 실험적 해석)

  • Jo, Jun-Han;Kim, Seong-Ho;No, Jeong-Hyeon
    • Journal of Korean Society of Transportation
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    • v.27 no.2
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    • pp.23-34
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    • 2009
  • This paper is described as an experimental analysis for the probabilistic directional design hour volume estimation. The main objective of this paper is to derive acceptable design rankings, PK factors, and PD factors. In order to determine an appropriate distribution for acceptable design rankings, 12 probability distribution functions were employed. The parameters were estimated based on the method of maximum likelihood. The goodness of fit test was performed with a Kolmogorov-Smirnov test. The Beta General distribution among the probability distributions was selected as an appropriate model for 2 lane roadways. On the other hand, the Weibull distribution is superior for 4 lanes. The method of the inverse cumulative distribution function came up with an acceptable design ranking of design for LOS D. An acceptable design ranking of 2 lanes is 190, while an acceptable design ranking for 4 lanes is 164. The PK factor and PD factor of 2 lanes was elicited for 0.119 (0.100-0.139) and 0.568 (0.545-0.590), respectively. On the other hand, the PK factor and PD factor for 4 lanes was elicited as 0.106 (0.097-0.114) and 0.571 (0.544-0.598), respectively.

Ordinary kriging approach to predicting long-term particulate matter concentrations in seven major Korean cities

  • Kim, Sun-Young;Yi, Seon-Ju;Eum, Young Seob;Choi, Hae-Jin;Shin, Hyesop;Ryou, Hyoung Gon;Kim, Ho
    • Environmental Analysis Health and Toxicology
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    • v.29
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    • pp.12.1-12.8
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    • 2014
  • Objectives Cohort studies of associations between air pollution and health have used exposure prediction approaches to estimate individual-level concentrations. A common prediction method used in Korean cohort studies is ordinary kriging. In this study, performance of ordinary kriging models for long-term particulate matter less than or equal to $10{\mu}m$ in diameter ($PM_{10}$) concentrations in seven major Korean cities was investigated with a focus on spatial prediction ability. Methods We obtained hourly $PM_{10}$ data for 2010 at 226 urban-ambient monitoring sites in South Korea and computed annual average $PM_{10}$ concentrations at each site. Given the annual averages, we developed ordinary kriging prediction models for each of the seven major cities and for the entire country by using an exponential covariance reference model and a maximum likelihood estimation method. For model evaluation, cross-validation was performed and mean square error and R-squared ($R^2$) statistics were computed. Results Mean annual average $PM_{10}$ concentrations in the seven major cities ranged between 45.5 and $66.0{\mu}g/m^3$ (standard deviation=2.40 and $9.51{\mu}g/m^3$, respectively). Cross-validated $R^2$ values in Seoul and Busan were 0.31 and 0.23, respectively, whereas the other five cities had $R^2$ values of zero. The national model produced a higher cross-validated $R^2$ (0.36) than those for the city-specific models. Conclusions In general, the ordinary kriging models performed poorly for the seven major cities and the entire country of South Korea, but the model performance was better in the national model. To improve model performance, future studies should examine different prediction approaches that incorporate $PM_{10}$ source characteristics.

Improving the Usage of the Korea Meteorological Administration's Digital Forecasts in Agriculture: IV. Estimation of Daily Sunshine Duration and Solar Radiation Based on 'Sky Condition' Product (기상청 동네예보의 영농활용도 증진을 위한 방안: IV. '하늘상태'를 이용한 일조시간 및 일 적산 일사량 상세화)

  • Kim, Soo-ock;Yun, Jin I.
    • Korean Journal of Agricultural and Forest Meteorology
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    • v.17 no.4
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    • pp.281-289
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    • 2015
  • Information on sunshine duration and solar radiation are indispensable to the understanding of crop growth and development. Yet, relevant variables are not available in the Korea Meteorological Administration's (KMA) digital forecast. We proposed the methods of estimating sunshine duration and solar radiation based on the 'sky condition' of digital forecast products and validated using the observed data. The sky condition values (1 for clear, 2 for partly cloudy, 3 for cloudy, and 4 for overcast) were collected from 22 weather stations at 3-hourly intervals from August 2013 to July 2015. According to the observed relationship, these data were converted to the corresponding amount of clouds on the 0 to 10 scale (0 for clear, 4 for partly cloudy, 7 for cloudy, and 10 for overcast). An equation for the cloud amount-sunshine duration conversion was derived from the 3-year observation data at three weather stations with the highest clear day sunshine ratio (i.e., Daegwallyeong, Bukgangneung, and Busan). Then, the estimated sunshine hour data were used to run the Angstrom-Prescott model which was parameterized with the long-term KMA observations, resulting in daily solar radiation for the three weather stations. Comparison of the estimated sunshine duration and solar radiation with the observed at those three stations showed that the root mean square error ranged from 1.5 to 1.7 hours for sunshine duration and from 2.5 to $3.0MJ\;m^{-2}\;day^{-1}$ for solar radiation, respectively.

Method Extracting Observation Data by Spatial Factor for Analysis of Selective Attention of Vision (시각의 선택적 주의집중 분석을 위한 공간요소별 주시데이터 추출방법)

  • Kim, Jong-Ha;Kim, Ju-Yeon
    • Science of Emotion and Sensibility
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    • v.18 no.4
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    • pp.3-14
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    • 2015
  • This study has extracted observation data by spatial factor for the analysis of subjects' selective attention with the objects of public space at the entrance of subway stations. The methods extracting observation data can be summarized as the following. First, the frequency analysis by lattice was prevalent for those methods, but there is a limitation to the analysis of the observation data. On the contrary, the method extracting observation data by factor applied in this study can make it clear if any sight is concentrated on any particular factors in a space. Second, the results from the extracted data corresponding to the observation area can be objectified while the method setting up the observation area by applying the radius of fovea. Third, time-sequential trace of observation results of relevant factors was possible through hourly analysis of spatial factors. The consideration of the results of "corresponding spatial scope" which is the object of this study will reveal that the more the observation time, the less the degree of attention it receives. Fourth, the frequency of observation superiority was applied for the analysis of the sections with selective attention by time scope; this revealed that men and women had intensive observation in time scope I (52.4 %) and in time scope IV (24.0 %), respectively.

Compatibility of DOAS and Conventional Point Monitoring System Through an Evaluation of Bias Structures Using Long-term Measurement Data in Seoul (장기관측자료를 이용한 DOAS와 점측정 분석시스템의 바이어스 구조에 대한 평가)

  • 김기현;김민영
    • Journal of Korean Society for Atmospheric Environment
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    • v.17 no.5
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    • pp.395-405
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    • 2001
  • To make an assessment of the compatibility between DOAS and conventional point monitoring system (MCSAM-2: MS2), we investigated the concentrations of three criteria pollutants which include S $O_2$, N $O_2$, and $O_3$from a national monitoring station in Seoul during the periods of June 1999~August 2000. The average concentration values for the whole study period derived from hourly concentration data sets of those three species indicated that the mean differences between the two methods can be approximated as 18%. When the bias structure of two systems was evaluated through the computation of percent difference(PD) between the two such as ( $C_{DOAS}$- $C_{conventional}$ $C_{DOAS}$*100, differences between the two systems appeared to be quite systematic among different compounds. While the mode of bias peaked at 0~20% or 20~40% in terms of PD values, the cause of such positive bias mainly arised from generally enhanced concentration values of DOAS system. The structure of bias among different species was further assessed through linear regression analysis. Results of the analysis indicated that the dominant portions of differences observed from two monitoring systems can be accounted for by the systematic differences in their spanning and zeroing systems. S $O_2$(MS2)=0.6385 S $O_2$(DOAS)+2.0985($r^2$=0.7894) N $O_2$(MS2)=0.6548 N $O_2$(DOAS)+7.437($r^2$=0.7687) $O_3$(MS2)=1.0359 $O_3$(DOAS)-7.7885($r^2$=0.7944) The findings of slope values at around 0.64~0.65 from two species suggest that DOAS should respond more sensitively in upper bound concentration range. The offset values apart from zero indicate that more deliberate comparison needs to be made between these monitoring systems. However, based on the existence of strong correlations from at least 8,000 data points for each species of comparison, we were able to conclude that the compatibility of two monitoring systems is highly significant. With the improvement of calibration techniques for the DOAS system. its applicability for routine monitoring of airborne pollutant species is expected to be quite extendable.

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