• 대한한방소아과학회지
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• 제17권2호
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• pp.149-160
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• 2003

Objective : Essential oil inhalation and He-Ne laser treatment has become increasingly available in children with nasal diseases. But the reports on the effect and prognosis have been poor. In this study, we analyzed the treatment effect, recurrence rate and the degree of recurrent symptoms. Materials/Methods: 23 children(2-10 year-old) with nasal diseases, who received essential oil inhalation with He-Ne laser treatment at least 10 times in our hospital from January 1st 2001 to December 31th 2002 were studied. Result : Ten cases are male & thirteen cases are female. The average of age was 4.91 year-old. The most frequency symptoms are nasal discharge (82.6%), nasal obstruction (78.3%), cough (47.8%), secretion sound (39.1%), sneezing (17.4%). Average numbers of treatment period, interval and treatment times are 71.79 days, 4.06 days, 18.13 times respectively. Of the 23 children, 14 children were in 'all symptom improved' at the remedial ends, and 22 children relapsed. In the degree of recurrent symptoms, 15 children were in 'more improved then before-treatment and not equal to directly remedial ends'. No case was in 'worse than before-treatment'. The final result of treatment, 6 children keep the degree of remedial ends, on the other hand 17 children are not. Conclusions : Even though, the recurrence rate was high, this combined treatment improve nasal symptoms. The final assessment is good, when the treatment-result is good, when the treatment interval is regular and when parent's are cooperative. If the symptoms continue a whole year, the result is not so good.

• 한국식품영양과학회:학술대회논문집
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• 한국식품영양과학회 2001년도 International Symposium on Food,Nutrition and Health for 21st Century
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• pp.52-60
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• 2001

Purpose: We performed a randomized, double-blind, placebo-controlled trial in mild to moderate myopia patients to evaluate the benefit of taking a nutrient supplement containing anthocyanoside oligomers for improving nocturnal visiual function and/or clinical symptoms. Methods: The subjects included have refractive error between -lD(Diopters) $\~$-8D in both eyes, symptoms of decreased night vision and asthenopia based on the scoring result of a pre-structured questionnaire, and abnormal results of mesopic contrast sensitivity(MCS) screening test showing abnormal curve of contrast sensitivity in the middle and high frequency level, between 6.0 and 30.0 CPD(Cycles per degree) at mesopic condition(-2$\~$0 log cd/$m^2$). Total 60 people who qualified the criteria above were enrolled and the subjects were instructed to take the investigational product (anthocyanoside or placebo) twice daily for a 4 week period. The enrolled subjects were investigated for nocturnal vision performance by MCS and clinical symptoms at their first visit and re-evaluated at post-intervention (4 weeks later). MCS was measured and improvement of contrast threshold level according to each CPD was calculated by subtracting initial values from final values. Age, refractive error, and MCS were compared between the placebo and anthocyanoside. Results: After 4 weeks of drug administration 22 of the anthocyanoside group showed symptom improvement compared to 1 of the placebo group (p=0.000). Contrast sensitivity levels according to each CPD before and after drug treatment showed significant improvement in the anthocyanoside group but not in the placebo group. Mean MCS change of anthocyanoside group is 2.41$\pm$1.91 which showed significant improvement compared to -0.40$\pm$2.47 of the placebo group(p=0.000). MCS changes of anthocyanoside group showed significant improvement compared to placebo group in all levels of CPD(p<0.05). During our investigation none of the subjects complained of specific side effects related to anthocyanoside use. Conclusion: Our results show that under careful selection of people with significant symptoms and definite MCS abnormalities, anthocyanoside oligomers may improve the subjective symptoms and objective MCS results.

• 혜화의학회지
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• 제13권2호
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• pp.231-249
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• 2004

This study analyzed the contents of the research papers concerning the common cold recorded in Chinese medical journal published over the period between 2000 and 2004. As a result, the following conclusion was drawn. 1. Among the clinical research papers, There are a lot of treatment papers of traditional chinese medicine in the method of treatment. There are a lot of papers about Feng-Re-Xing(風熱型) and Xu-Zheng-Xing(虛證型) in the Bian-Zheng-Lei-Xing(辨證類型) 2. "Zhong-Yi-Xu-Zheng-Bian-Zheng-Can-Kao-Biao-Zhun" ("中醫虛證辨證參考標準"), "Zhong-Yi-Nei-Ke-Wu-Ban-Jiao-Cai"("中醫內科五版敎材"), "Zhong-Hua-Ren-Min-Gong-He-Guo-Zhong-Yi-Yao-Hang-Ye-Biao-Zhun"("中華人民共和國醫藥行業標準"), "Gan-Mao-Zhen-Duan-Biao-Zhun"("感冒診斷漂準"), "Zhong-Yi-Bing-Zheng-Zhen-Duan-Liao-Xiao-Biao-Zhun"("中醫病證診斷療效標準"), "Quan-Guo-Gao-Deng-Yi-Xue-Yuan-Xiao-Zhong-Yi-Zhuan-Ye-Jiao-Cai"("全國高等醫藥院校中醫專業敎材") are used as the criterion for diagnosis in Chinese medicine. 3. It is mainly used "Zhong-Yi-Bing-Zheng-Zhen-Duan-Liao-Xiao-Biao-Zhun"("中醫病證診斷療效標準") as the criterion for treatment effect evaluation, and symptom of traditional chinese medicine, the frequency and the duration of common cold, measurement of immunologic function are used as assistant evaluation indicator. 4. The research papers reported that the use of prescriptions such as Chai-Qi-Fang-Jiao-Tang, Tui-Re-He-Ji(退熱合劑), Ti-Xu-Gan-Mao-He-Ji(體虛感冒合劑), Yu-Ping-Feng-San-He-Gui-Zhi-Tang(玉屛風散合桂枝湯), Chai-Guan-Jie-Re-Ke-Li(柴貫解熱顆粒), Hu-Qin-He-Ji(蒿芩合劑), Lian-Hua-Feng-Cha(蓮花峰茶), Kang-Gan-He-Ji(抗感合劑), Bing-Du-He-Ji(病毒合劑), Zhong-Gan-Ling-Pian(重感靈片) led to the high efficacy 5. The pharmacological research papers reported that Yu-Ping-Feng-San(玉屛風散) have influence on IgA, phagocytic function of macrophage, the total number of splenocyte and PEC.

• 대한기관식도과학회:학술대회논문집
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• 대한기관식도과학회 1977년도 제11차 학술대회연제 순서 및 초록
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• pp.3.1-3
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• 1977

스트레프토마이신 중독성난청은 오늘날 이과학적 문제로 제기된지 오래이며, 선진각국에서는 많은 이방면의 연구가 이루워져 있다. 근년에 와서는 의수나 환자가 다같이 이방면에 관심을 가지게 되었다. 연자들은 우리나라에서의 스트레프토마이신 중독성난청 실태를 알기 위하여 폐결핵 치료목적으로 국립마산병원에 입원한 198례(남자 131례, 여자 671례)를 대상으로 스트레프토마이신 중독성난청의 빈도를 임상적으로 관찰하여 그 지견을 다음과 같이 요약한다. 1. 스트레프토마이신 중독성난청의 발생빈도는 198례중 30례로서 15.2%였다. 2. 스트레프토마이신 중독성난청은 투여한 스트레프토마이신량의 증가에 따라 많아지는 경향이 었다. 3. 스트레프토마이신 중독성난청은 1일 1gm 연일투여례에서 발생율이 많았고 (17.4%), 주 2회, 1회 1gm 투여례에서 적었다(2.9%). 4. 스트레프토마이신 투여에 의한 합병증은 59례(2.98%)였으며, 스트레프토마이신 중독성난청 30례중 이명을 동반한 것이 14례(46.7%)로 가장 많았다. 5. 스트레프토마이신 중독성난청은 고음역에서 시작하여 점차 회화음역으로 파급하는 경향이었다. 6. 청력도형은 고음점경형(40.4)과 수평형(30.3%)이 많았다.

• 한국융합학회논문지
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• 제11권9호
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• pp.83-90
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• 2020

본 연구는 청소년의 건강행태와 증상의 관련성을 파악하여 청소년기의 구강건강을 유지하기 위한 교육 프로그램 개발에 관한 자료를 제공하는데 목적이 있다. 제15차(2019년) 청소년건강행태온라인 조사자료를 이용하여 고등학생 27,919명을 대상으로 하였다. 구강 증상에 미치는 영향요인을 로지스틱 회귀분석한 결과 잇몸 통증 증상을 낮게 인지한 경우는 남자, 저학년, 소득수준이 높은 경우, 주관적 구강건강 인지가 매우 좋은 경우 유의하게 낮았다. 스트레스가 높은 경우는 통증 인지가 높아 통계적으로 유의했다. 구취 증상을 높게 인지한 경우로는 남자, 스트레스가 높은 경우, 1일 잇솔질 실천 횟수가 적은 경우 유의하게 높았다. 소득이 높은 경우, 주관적 구강건강 인지가 매우 좋은 경우에는 구취 인지가 낮아 통계적으로 유의했다. 본 연구는 청소년의 건강행태가 구강 증상에 영향 미치는 것을 알 수 있었고, 이러한 구강 증상을 예방할 수 있는 교육 프로그램 개발에 도움을 주고자 한다.

• 사상체질의학회지
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• 제31권1호
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• pp.65-78
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• 2019

Objectives This study aims to investigate how the Korean disease-related vocabulary is established or changed when it is translated into French or English. Through this, we examine changes in the meaning of diseases and the ecosystem of disease-related vocabulary in transition period of $19^{th}$ to $20^{th}$ century. Methods Korean disease-related vocabulary are extracted from a total of 148,000 Korean headwords included in our corpus of three bilingual dictionaries. Among them, the scope of analyisis is limited to group of vocabularies that include a high frequency words, disease(病) and symptom(症). Results The first type of change is the emergence of a neologism. In this case, coexistence of existing vocabulary and new words is observed. The second change is the appearance of loan words written in Hangul. The third is the case where the interpretation of meaning is changed while maintaining the word form. Finally, the fourth change is that the orthographic variants are displayed while maintaining the meaning of the existing vocabulary. Discussion Disease-related vocabulary increased greatly between 1897 and 1931. The increasing factor of vocabulary was the emergence of coined words, compound words and the influx of foreign words. The Korean language and the Western language made a new lexical form in order to introduce a new unknown concept to the Korean. We could also confirm that the way in which English word expanded its semantic field by modifying the way of representing the meaning of Korean Disease-related vocabulary.

• 치위생과학회지
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• 제9권3호
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• pp.361-367
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• 2009

본 연구는 치과내원환자 334명을 대상으로 치과공포 및 행태에 따른 구강악안면증상을 알아보고자 연구를 시행하였다. 성별과 연령, 치과이용행태 등의 일반적 특성 5문항, 20개문항의 DFS, 스트레스 증상설문지 (Stress Symptom Questionnaire) 20문항을 이용하여 설문조사한 후 얻어진 자료들을 SPSS 12.0을 사용하여 검정하였다. 분석한 결과는 다음과 같다. 1. 여성이 남성보다 공포가 높았고, 연령은 30세 이상에서 공포가 높게 나타났으며, 통계적으로 유의하게 나타났다(p<0.05). 2. 치과진료회피반응, 생리적 반응, 공포유발자극요인 중에서 치료자극반응이 가장 높았으며, 성별과 비교해서는 여성이 모두 높은 점수를 보였으며, 통계적으로 매우 유의하였다(p<0.01). 3. 구강악안면증상부위에 따른 반응정도는 기타 구강외 증상이 62.9%로 가장 높았으며, 항목으로는 뒷머리가 당기거나 목덜미가 뻣뻣하다가 가장 높은 것으로 나타났다. 4. 일반적 특성에 따른 구강악안면증상은 성별에서 혀에서만 유의하였고(p<0.05), 연령은 30세 이상에서 입술이나 볼안쪽, 기타 구강외증상이 더 높게 나타났다. 5. 정기검진을 하는 경우, 스켈링경험이 있는 경우, 마취경험이 있는 경우, 내원횟수가 많은 경우 구강악안면증상이 높았으며, 통계적으로는 스켈링경험이 있는 경우와 내원횟수가 많은 경우가 혀에서만 유의하게 나타났다(p<0.05). 6. 공포정도에 따른 구강악안면증상은 고공포 그룹에서 각 부위별 구강악안면증상이 높게 나타났고, 통계적으로도 모두 유의하게 나타났으며, 공포와 각 구강악안면증상 간에 양의 상관관계를 나타내었으며 통계적으로도 유의하였다(p<0.05).

• 정신신체의학
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• 제7권2호
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• pp.174-183
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• 1999

본 연구는 자동차사고 이후 신체적 증상에 대한 치료를 받은 후 정신과적 진단 및 치료 또는 정신감정을 위해 정신과로 의뢰되었던 44명의 환자를 대상으로 자동차사고와 외상후 스트레스장애와의 관계를 평가하기 위한 것이다. 외상후 스트레스장애 진단은 외상후 스트레스장애 척도(CAPS)를 사용하여 DSM-IV 진단기준에 따라 분류하였고, 축소형 부상척도(AIS)를 사용하여 신체적 손상과 외상후 스트레스장애 증상과의 관계를 조사하고 외상후 스트레스장애와 Axis I 공존질환 유무에 대해 알아 보았다. 자동차 사고후 정신과에 의뢰된 대상자 44명중 20명(45.5%)이 외상후 스트레스장애로 진단되었고 13명(29.5%)이 아증후성 외상후 스트레스장애에 속하였다. 신체적 부상의 정도는 외상후 스트레스장애 증상을 예견하는 것으로 나타났다. 외상후 스트레스장애군은 외상후 스트레스장애 진단 기준 BCD 모든 증상에서 높은 비율을 나타냈고, 아증후성 외상후 스트레스장애군은 기준 B와 D 증상에서 비교적 높은 비율을 나타냈으며, 두 군 모두 기준 B 가운데 '사건에 대한 반복된 꿈' 항목의 비율이 가장 높았다. 외상후 스트레스장애군의 55%가 주요우울증을 동반하였다. 결론적으로 본연구의 결과는 외상후 스트레스장애가 자동차사고 이후 흔히 올 수 있는 정신장애임을 시사하고 있다. 따라서 자동차사고 후 신체적 손상에 대한 치료를 받고 마지막으로 정신과에 의뢰된 환자들에 대해서는 적어도 치료계획에서 외상후 스트레스장애라는 진단을 정규적으로 고려해야만 할 젓이고. 특히 취약성이 있는 환자들에 대해서는 조기 중재가 외상후 스트레스장애 증상을 예방할 수 있을 것이라고 생각된다.

• 대한치과의사협회지
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• 제50권9호
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• pp.566-573
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• 2012

Purpose : This study evaluated the impact of the presence and aspect of mandibular third molars to the mandible angle fracture or condyle fractures in Korean. Materials and Methods : A retrospective study was designed for patients attending the division of Oral and Maxillofacial Surgery, Kang-dong sacred heart hospital for treatment of mandibular fracture from January 2006 to September 2010. The primary variable was the presence of mandibular third molar and the secondary variable was the aspects of third molar impaction. Mandibular third molars were classified by the impaction depth and the available space as Pell & Gregory system. Outcome variables were the presence of mandibular angle fracture or condyle fracture. Also the source of trauma, age, sex were studied. Hospital charts, radiographs were used for study. Statistic analysis was done with descriptive statistics, the X2-test, linear-by-linear association. P value under 0.05 was considered significant statistically. Results : The number of involved patients was 86. The ratio of male to female patients was about 9:1 for angle fracture and 7:3 for condyle fracture. The most common source of trauma was assault for angle fracture and fall down for condyle fracture. The presence of mandibular third molar increased frequency of angle fracture and decreased condyle fracture with larger impaction depth. But available space of mandibular third molar did not show high association with angle or condyle fractures. Conclusion: Preventive extraction of mandibular third molar is recommended for patients with high risk of angle fracture. Male patients at their third decade or martial artists, police officer could be the case. But it is not recommended for patients with low risk of angle fracture and high risk of condyle fracture relatively. Elder female patients without any symptom on their third molar could be the case.

• Asian Pacific Journal of Cancer Prevention
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• 제16권17호
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• pp.7467-7472
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• 2015

Background: Breast cancer is known to be one of the most prevalent cancers among women in both developing and developed countries. The incidence of breast cancer in Pakistan has increased dramatically within the last few years and is the second country after Israel in Asia to have highest proportional cases of breast cancer. However, there are limited data for breast cancer available in the literature from Pakistan. Objectives: The study was conducted to bring to light the common clinical presentation of breast cancer and to evaluate the frequency of established risk factors in breast carcinoma patients and furthermore to compare the findings between premenopausal and postmenopausal women in Pakistan. Materials and Methods: A 6 months (from July 2012 to Dec 2012) cross sectional survey was conducted in Surgical and Oncology Units of Civil Hospital, Karachi. Data were collected though a well developed questionnaire from 105 female patients diagnosed with carcinoma of breast and analyzed using SPSS version 17. Institutional ethical approval was obtained prior to data collection. Results: Out of 105 patients, 43 were premenopausal and 62 were postmenopausal, 99 being married. Mean age at diagnosis was $47.8{\pm}12.4years$. A painless lump was the most frequent symptom, notived by 77.1%(n=81). Some 55.2% (n=58) patients had a lump in the right breast and 44.8%(n=47) in the left breast. In the majority of cases, the lump was present in upper outer quadrant 41.9% (n=44). Mean period of delay from appearance of symptoms to consulting a doctor was $5.13{\pm}4.8months$, from the shortest 1 month to the longest 36 months. Long delay (> 3 months) was the most frequent figure 41.9%. Considering overall risk factors most frequent were first pregnancy after 20 years of age (41%), physical breast trauma (28.6%), lack of breast feeding(21.9%), and early menarche <11 years (19%), followed by null parity (16.2%), consumption of high fat diet (15.2%), family history of breast cancer or any other cancer in first degree relatives (9.5% and 13.3%, respectively). Some of the less common factors were late menopause >54 years (8.6%), use of oral contraceptive pills (10.5%), use of hormone replacement therapy (4.7%),smoking (4.7%) and radiation (0.96%). Significant differences (p<0.005) were observed between pre and post menopausal women regarding history of physical breast trauma, practice of breast feeding and parity. Conclusions: A painless lump was the most frequent clinical presentation noted. Overall age at first child > 20 years, physical breast trauma, lack of breast feeding, early menarche <11 were the most frequent risk factors. Physical breast trauma, lower parity, a trend for less breast feeding had more significant associations with pre-menopausal than post-menopausal onset. Increase opportunity of disease prevention can be obtained through better understanding of clinical presentation and risk factors important in the etiology of breast cancer.