Objective: Dairy cattle nutrient requirement systems acknowledge amino acid (AAs) requirements in aggregate as metabolizable protein (MP) and assume fixed efficiencies of MP used for milk protein. Regulation of mammary protein synthesis may be associated with AA input and milk protein output. The aim of this study was to evaluate the effect of nanoemulsified methionine and cysteine on the in-vitro expression of milk protein (casein) in bovine mammary epithelial cells (MAC-T cells). Methods: Methionine and cysteine were nonionized using Lipoid S 75 by high-speed homogenizer. The nanoemulsified AA particle size and polydispersity index were determined by dynamic light scattering correlation spectroscopy using a high-performance particle sizer instrument. 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay was performed to determine the cytotoxicity effect of AAs with and without nanoionization at various concentrations (100 to $500{\mu}g/mL$) in mammary epithelial cells. MAC-T cells were subjected to 100% of free AA and nanoemulsified AA concentration in Dulbecco's modified Eagle medium/nutrient mixture F-12 (DMEM/F12) for the analysis of milk protein (casein) expression by the quantitative reverse transcription polymerase chain reaction method. Results: The AA-treated cells showed that cell viability tended to decrease (80%) in proportion to the concentration before nanogenesis, but cell viability increased as much as 90% after nanogenesis. The analysis of the expression of genetic markers related to milk protein indicated that; ${\alpha}_{s2}$-casein increased 2-fold, ${\kappa}$-casein increased 5-fold, and the amount of unchanged ${\beta}$-casein expression was nearly doubled in the nanoemulsified methionine-treated group when compared with the free-nanoemulsified methionine-supplemented group. On the contrary, the non-emulsified cysteine-administered group showed higher expression of genetic markers related to milk protein ${\alpha}_{s2}$-casein, ${\kappa}$-casein, and ${\beta}$-casein, but all the genetic markers related to milk protein decreased significantly after nanoemulsification. Conclusion: Detailed knowledge of factors, such nanogenesis of methionine, associated with increasing cysteine and decreasing production of genetic markers related to milk protein (casein) will help guide future recommendations to producers for maximizing milk yield with a high level of milk protein casein.
Recent advances in large-scale data processing technologies such as big data, cloud computing, and artificial intelligence have increased the demand for high-performance storage devices in data centers and enterprise environments. In particular, the fast data response speed of storage devices is a key factor that determines the overall system performance. Solid state drives (SSDs) based on the Non-Volatile Memory Express (NVMe) interface are gaining traction, but new bottlenecks are emerging in the process of handling large data input and output requests from multiple hosts simultaneously. SSDs typically process host requests by sequentially stacking them in an internal queue. When long transfer length requests are processed first, shorter requests wait longer, increasing the average response time. To solve this problem, data transfer timeout and data partitioning methods have been proposed, but they do not provide a fundamental solution. In this paper, we propose a dual queue based scheduling scheme (DQBS), which manages the data transfer order based on the request order in one queue and the transfer length in the other queue. Then, the request time and transmission length are comprehensively considered to determine the efficient data transmission order. This enables the balanced processing of long and short requests, thus reducing the overall average response time. The simulation results show that the proposed method outperforms the existing sequential processing method. This study presents a scheduling technique that maximizes data transfer efficiency in a high-performance SSD environment, which is expected to contribute to the development of next-generation high-performance storage systems
Park, Beom-Soo;Kim, Young-Ju;Park, Seung-Jae;Lee, Seung-Hoon
Journal of the Institute of Electronics Engineers of Korea SD
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제46권3호
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pp.60-68
/
2009
This work proposes a 10b 200MS/s 65nm CMOS ADC for high-definition video systems such as HDTV requiring high resolution and fast operating speed simultaneously. The proposed ADC employs a four-step pipeline architecture to minimize power consumption and chip area. The input SHA based on four capacitors reduces the output signal range from $1.4V_{p-p}$ to $1.0V_{p-p}$ considering high input signal levels at a low supply voltage of 1.2V. The proposed three-stage amplifiers in the input SHA and MDAC1 overcome the low output resistance problem as commonly observed in a 65nm CMOS process. The proposed multipath frequency-compensation technique enables the conventional RNMC based three-stage amplifiers to achieve a stable operation at a high sampling rate of 200MS/s. The conventional switched-bias power-reduction technique in the sub-ranging flash ADCs further reduces power consumption while the reference generator integrated on chip with optional off-chip reference voltages allows versatile system a locations. The prototype ADC in a 65nm CMOS technology demonstrates a measured DNL and INL within 0.19LSB and 0.61LSB, respectively. The ADC shows a maximum SNDR of 54.BdB and 52.4dB and a maximum SFDR of 72.9dB and 64.8dB at 150MS/S and 200MS/s, respectively. The proposed ADC occupies an active die area of $0.76mm^2$ and consumes 75.6mW at a 1.2V supply voltage.
To design more efficient agricultural machinery, the accurately measuring system among many other factors is essential. A light-beam oscillographic recorder is generally used in measuring dynamic strain but it is not compatible with the extremely high speed measuring system such as 1,000 m/s, also is susceptable to damage due to vibration while using the system in field. The recorder used light sensitive paper for strip chart recording. The reading and analysis of data from the strip charts is very cumbersome, errorneous and time consuming. A microcomputer was interfaced with A/D converter, microcomputer program was developed for measuring, system calibration was done and the strain generated from a cantilever beam vibrator was measured. The results are summarized as follows. 1. Microcomputer program was developed to perform strain measuring of agricultural machine elements and could be controled freely the measuring intervals, no. of channels and no. of data. The maximum measuring speed was $62{\mu}s$. 2. Calibration the system was performed with triangle wave generated from a function generator and checked by an oscilloscope. The sampled data were processed using HP 3000 minicomputer of Chungnam National University computer center the graphical results were triangle same as input wave and so the system have been out of phase distorsion and amplitude distorsion. 3. The strain generated from a cantilever beam vibrator which has free vibration period of 0.019 second were measured by the system controlled to have l.0 ms of time interval and its computer output showing vibration curve which is well filted to theoretical value. 4. Using microcomputer on measuring the strain of agricultural machine elements could not only save analyzing time and recording papers but also get excellent adaptation to field experiment, especially in measurement requiring high speed and good precision.
Journal of the Institute of Electronics Engineers of Korea SD
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제48권1호
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pp.14-21
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2011
A 10b 500MS/s $0.13{\mu}m$ CMOS ADC is proposed for 4G wireless communication systems such as a LTE-Advanced and SDR The ADC employs a calibration-free single-channel folding architecture for low power consumption and high speed conversion rate. In order to overcome the disadvantage of high folding rate, at the fine 7b ADC, a cascaded folding-interpolating technique is proposed. Further, a folding amplifier with the folded cascode output stage is also discussed in the block of folding bus, to improve the bandwidth limitation and voltage gain by parasitic capacitances. The chip has been fabricated with $0.13{\mu}m$ 1P6M CMOS technology, the effective chip area is $1.5mm^2$. The measured results of INL and DNL are within 2.95LSB and l.24LSB at 10b resolution, respectively. The SNDR is 54.8dB and SFDR is 63.4dBc when the input frequency is 9.27MHz at sampling frequency of 500MHz. The ADC consumes 150mW($300{\mu}W/MS/s$) including peripheral circuits at 500MS/s and 1.2V(1.5V) power supply.
The purpose of this study was to develop the handy non-contact measurement device of the surface roughness by using the optical fiber sensor. The advantages of fiber optic sensors are high-speed responsibility, non-effect of the magnetic, convenience of the product and high precision. The measurement theory for surface roughness of optical fiber sensor is one to one correspondence between the reflected light intensity based on the surface roughness of the object and the measurement value of previously known for surface roughness. The reflected light intensity was determined using the distance to the surface from the sensor probe and the limit reflection angle based on the surface roughness. Therefore, in this study, the sensor probe was produced for determining the value of surface roughness only using the limit reflection angle based on the surface roughness with the fixed distance from the surface. A prototype measurement system was composed of a transmitting part, a receiving part and a signal processing circuit. The materials of standard measurement which was used in this experiment were SM45C, STS303 and Al60. According to the results of this study, approximation surface roughness formulas which was deduced from the correlation of between the standard surface roughness and the sensing output were verified that they were effect against the surface roughness measurement value of the option sample. And handy optical fiber surface roughness measurement device which was produced by an order was verified that it was effect for measuring of the precision surface roughness.
The Journal of the Korea institute of electronic communication sciences
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제11권5호
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pp.531-538
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2016
Driving behaviors such as speeding and illegal u-turn which violate traffic rules are main causes of car accidents, and they can lead to serious accidents. Bus drivers are less aware of dangers of illegal u-turn, and infrastructures such as traffic enforcement equipment and watchmen are deficient. This research aims to develop technology for estimating driving behaviors based on map-matching in order to prevent illegal u-turns. For this research, 23,782 of u-turn permit data and 146,000 of speed limit data are collected nationwide, and an estimation algorithm is built with these data. Then, an application based on android is developed, and finally, tests are conducted to assess the accuracy in data computations and GPS data map-matching, and to extrapolate driving behavior. As a result of the tests, the accuracy results in the map-matching is 86% and the assessment of driving behavior is 83%, while the display of the data output yielded 100% accuracy. Additional research should focus on improvement in accuracy through the development of a robust monitoring system, and study of service scenarios for technology application.
The purpose of this paper is to show the clustering trend and to choose the clustering ports for 3 Korean ports(Busan, Incheon and Gwangyang Ports) by using the self organizing maps based on neural network(SOM) and Tier models for 38 Asian ports during 11 years(2001-2011) with 4 input variables(birth length, depth, total area, and number of crane) and 1 output variable(container TEU). The main empirical results of this paper are as follows. First, clustering results by using SOM show that 3 Korean ports[Busan(26.5%), Incheon(13.05%), and Gwangyang(22.95%) each]can increase the efficiency. Second, according to Tier model, Busan(Hongkong, Sanghai, Manila, and Singapore), Incheon(Aden, Ningbo, Dabao, and Bangkog), and Gwangyang(Aden, Ningbo, Bangkog, Hipa, Dubai, and Guangzhou) should be clustered with those ports in parentheses. Third, when both SOM and Tier models are mixed, (1) efficiency improvement of Busan Port is greater than those of Incheon and Gwangyang ports. (2) Incheon port has shown the slow improvement during 2001-2007, but after 2008, improvement speed was high. (3) improvement level of Gwangyang port was high during 2001-2003, but after 2004, improvement level was constantly decreased. The policy implication of this paper is that Korean port policy planner should introduce the SOM, and Tier models with the mixed two models when clustering among the Asian ports for enhancing the efficiency of inputs and outputs.
The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
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제27권3호
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pp.127-143
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2022
Recently, many attempts to run numerical ocean models in cloud computing environments have been tried actively. A cloud computing environment can be an effective means to implement numerical ocean models requiring a large-scale resource or quickly preparing modeling environment for global or large-scale grids. Many commercial and private cloud computing systems provide technologies such as virtualization, high-performance CPUs and instances, ether-net based high-performance-networking, and remote direct memory access for High Performance Computing (HPC). These new features facilitate ocean modeling experimentation on commercial cloud computing systems. Many scientists and engineers expect cloud computing to become mainstream in the near future. Analysis of the performance and features of commercial cloud services for numerical modeling is essential in order to select appropriate systems as this can help to minimize execution time and the amount of resources utilized. The effect of cache memory is large in the processing structure of the ocean numerical model, which processes input/output of data in a multidimensional array structure, and the speed of the network is important due to the communication characteristics through which a large amount of data moves. In this study, the performance of the Regional Ocean Modeling System (ROMS), the High Performance Linpack (HPL) benchmarking software package, and STREAM, the memory benchmark were evaluated and compared on commercial cloud systems to provide information for the transition of other ocean models into cloud computing. Through analysis of actual performance data and configuration settings obtained from virtualization-based commercial clouds, we evaluated the efficiency of the computer resources for the various model grid sizes in the virtualization-based cloud systems. We found that cache hierarchy and capacity are crucial in the performance of ROMS using huge memory. The memory latency time is also important in the performance. Increasing the number of cores to reduce the running time for numerical modeling is more effective with large grid sizes than with small grid sizes. Our analysis results will be helpful as a reference for constructing the best computing system in the cloud to minimize time and cost for numerical ocean modeling.
In this study, after developing an LSTM-based deep learning model for estimating daily runoff in the Soyang River Dam basin, the accuracy of the model for various combinations of model structure and input data was investigated. A model was built based on the database consisting of average daily precipitation, average daily temperature, average daily wind speed (input up to here), and daily average flow rate (output) during the first 12 years (1997.1.1-2008.12.31). The Nash-Sutcliffe Model Efficiency Coefficient (NSE) and RMSE were examined for validation using the flow discharge data of the later 12 years (2009.1.1-2020.12.31). The combination that showed the highest accuracy was the case in which all possible input data (12 years of daily precipitation, weather temperature, wind speed) were used on the LSTM model structure with 64 hidden units. The NSE and RMSE of the verification period were 0.862 and 76.8 m3/s, respectively. When the number of hidden units of LSTM exceeds 500, the performance degradation of the model due to overfitting begins to appear, and when the number of hidden units exceeds 1000, the overfitting problem becomes prominent. A model with very high performance (NSE=0.8~0.84) could be obtained when only 12 years of daily precipitation was used for model training. A model with reasonably high performance (NSE=0.63-0.85) when only one year of input data was used for model training. In particular, an accurate model (NSE=0.85) could be obtained if the one year of training data contains a wide magnitude of flow events such as extreme flow and droughts as well as normal events. If the training data includes both the normal and extreme flow rates, input data that is longer than 5 years did not significantly improve the model performance.
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