• 대한한의학방제학회지
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• 제23권2호
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• pp.209-224
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• 2015

Objective : The main purpose of this study is to find a reasonable solutions for utilization of herbal formulas based on the medical classics. Methods : We used official Ten 'Selected Korean Medical Classics(SKMC)'. For input of formulas from SKMC, we had to select proper editions of them. After consultations with experts of 'The Korean Medicine Society for the Herbal Formula Study' and 'Korean Society of Medical History', we chose the proper editions of SKMC, and according to those books, we built formulas database using microsoft office excel sheets, respectively. Results : After whole input procedures, we requested several experts to inspect the results and also, to correct errors in them. Input categories were name of formula, name of classic, classification, original source, composition herb, weight, unit of weight, weight conversion index, converted weight, basic formula, indications, reason for modification, preparing method, taking method and contraindications. Final number of whole formulas in DB was 32,882. Conclusions : We used SKMC and built database using excel program. Through this procedure, we can provide a developmental ways to make a foundation for herbal formulas from the medical classics, so that we can make herbal formulas be standardized or industrialized more efficiently.

• 한국식품영양학회지
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• 제34권6호
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• pp.662-668
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• 2021

Aster koraiensis Nakai (A. koraiensis) which has been used as a food and medicinal plant in the past, is valuable as functional food material. Therefore, the aim of this study was to determine the antioxidant properties and major phenolics of A. koraiensis extracts with different ethanol concentrations (0, 50, 70, and 100% aqueous ethanol solution). When ethanol concentration in the extraction solvent was increased, extraction yield decreased; 34.2, 23.2, 21.0, and 5.5% in 0, 50, 70, and 100% ethanolic extracts, respectively. Total phenolics content and antioxidant activities of extracts were increased in an ethanol concentration-dependant manner. The major phenolics in the extracts were chlorogenic acid (21.264~58.666 mg/g), isochlorogenic acid A (10.432~145.353 mg/g), and isochlorogenic acid C(0.239~13.148 mg/g), and these phenolic contents were higher in 70 and 100% ethanolic extracts than other extracts. Significant correlations were observed between ethanol concentration of extraction solvent, antioxidant properties, and major phenolics. These results indicated that the optimal ethanol concentration for extraction was 70%.

• 한국산림과학회지
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• 제99권5호
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• pp.762-769
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• 2010

The composition of minerals and amino acids in Allium victorialis var. platyphyllum tissues collected from different habitats in Ulleung Island and Mt. Hambeak of the Korean Peninsula is investigated. The mineral composition of A. victorialis stem was high compared to that of bulb in all population samples. The most abundant mineral found in all the samples was potassium (K). The mineral composition was variable in garlic population of Ulleung Island in a habitat dependent manner. The A. victorialis stems and bulbs showed significant differences in their amino acid compositions according to varying habitats of Ulleung Island and Mt. Hambeak. Among the amino acids the most abundant amino acid in A. victorialis bulb tissue was arginine, followed by leucine and valine. The amino acids leucine, valine, and phenylalanine were abundant in stem tissues. The total amino acids of the A. victorialis stem tissue from Teawha pass peak sample (837 mg/100 g dry wt) were higher than the mean of other population samples (355-824 mg/100 g dry wt). However, content of amino acids in the bulb was high in A. victorialis from Nari basin (1,919 mg/100 g dry wt).

• 한국식품영양학회지
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• 제27권3호
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• pp.331-338
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• 2014

The purpose of this study was to evaluate the jujube hot-water extraction and antioxidant. After extraction of hot-water jujube, general composition analysis and functional tests were performed. The results of general composition analysis showed 22.33% of moisture content, 0.71% of crude lipid, 5.21% of crude protein, and 3.87% of ash. From DPPH test results, in concentrations of $1,000{\mu}g/mL$ of jujube extracts, electron donating ability was shown with 68.24%. The SOD ability in concentrations of $1,000{\mu}g/mL$ was 13.12%. The nitrite scavenging ability of jujube extracts was 11.79% at $1,000{\mu}g/mL$. The yogurt with 0, 1, 2, 3 and 4% of jujube extracts was made, and the general composition analysis and the functional tests were performed. The results of the general composition analysis of jujube yogurt, showed 74.71~76.56% of moisture contents, 1.31~3.38% of crude lipid, 2.13~3.40% of crude protein, and 1.18~1.28% of ash. The DPPH test results showed 46.33% for 1% added jujube extract, 53.78% for 2% added jujube extract, 90.87% for 3% added jujube extract, and 89.58% for 4% added jujube extract. The SOD ability showed 4.93% for 1% added jujube extract, 7.28% for 2% added jujube extract, 11.38% for 3% added jujube extract, and 11.50% for 4% added jujube extract.

• 한국버섯학회지
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• 제18권1호
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• pp.120-124
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• 2020

팽이버섯 재배를 하고 있는 농가의 배지조성을 조사한 결과 농가마다 사용하는 배지재료의 종류와 혼합비율도 차이가 있었다. 모든 농가가 콘코브, 미강, 비트펄프를 주재료로 사용하였고, 배지의 적정 pH 조절을 위하여 탄산칼슘과 폐화석을 1.0~3.8%을 사용하였으며, 건비지, 밀기울, 면실피, 파옥쇄 등은 농가마다 사용하는 정도가 달랐다. 농가별 혼합배지의 이화학성을 분석한 결과 질소함량은 1.28~1.52%였고, 탄소함량은 45.7~48.5%, C/N율은 30.7~37.9였다. 무기성분 함량은 혼합배지에 들어가는 무기물의 종류와 양에 따라 농가마다 큰 차이를 보였다. 균사 생장량은 배양 34일후 농가 2에서 6.5 cm로 가장 빨랐고, 농가 4에서는 5.7 cm였으며, 농가 1, 농가 3, 농가 5에서는 균사 생장량이 건의 비슷하였다. 균사 밀도는 처리 간에 뚜렷한 차이가 없이 높은 밀도를 보였다. 농가별 배지조성에 따른 수량성을 조사한 결과 농가2에서 173.4 g/bottle로 가장 높은 수량을 보였으며, 농가 1에서는 168.4 g/bottle이였고, 농가 3과 4는 거의 비슷한 수량을 보였다. 그러나 농가 5는 145.4 g/bottle로 가장 낮은 수량을 보였다. 이와 같이 농가별 배지조성에 따라 팽이버섯의 수량이 차이를 보였으며, 이러한 결과를 참고하여 팽이버섯 재배농가에 범용적으로 사용할 수 있는 배지조성의 선발이 가능할 것으로 판단된다.

• 한국생물공학회:학술대회논문집
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• 한국생물공학회 2005년도 생물공학의 동향(XVII)
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• pp.926-927
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• 2005

• 한국환경복원기술학회지
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• 제11권6호
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• pp.38-48
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• 2008

This study was conducted to evaluate the vegetation structure of community by the phytosociology method, floristic composition table on coast of South Korea. Form 2007 June until November, $2m{\times}2m$ quadrat was established in native Glehnia littoralis in order to record a dominants and coverage, and it drew the profile. It was found out that the mean temperature in the distributed areas for Glehnia littoralis population was $11^{\circ}C$ or more. The flora of the studied area in Glehnia lottoralis community of coastal dune was listed as 100 species. Glehnia lottoralis community of appearance species of Yeonggwanggun Duwori was many most by 44 species. Carex pumila, Carex Kobomugi, Imperata cylindrica var. koenigii, Ischaemum anthephehoroides and Vitex rotundifolia range all over the studied areas. And the vegetation of Glehnia littoralis community was classified into Vitex rotundifolia subcommunity, Ischaemun anthephephoroides subcommunity and Imperata cylindrica var. koenigii subcommunity. Native Glehnia littoralis was classified into preserve area, natural selection area and artificial destruction area. It must preserve native Glehnia littoralis of Goseong, Yeongdeok, Haenam it was ecological important area.

• 대한한방소아과학회지
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• 제33권4호
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• pp.47-59
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• 2019

Objectives The purpose of this study is to analyze recent Chinese randomized controlled trials on efficacy and safety of the retention enema with herbal medicine in pediatric diarrhea. Methods We searched the recent Chinese randomized controlled trials from the China National Knowledge Infrastructure (CNKI) by using key words; '保留灌腸', '小兒', '腹瀉' and '泄瀉' with data range from January $1^{st}$, 2010 to March $2^{nd}$, 2019. Year of the publication, demographic information, disease, intervention, outcome measure, results, adverse events and composition of herbal medicine were analyzed for this study. Results 19 out of 32 studies were selected and analyzed. The most commonly used herbal medicine was Galgeungeumlyeon-tang modification (葛根芩連湯加減), and the most widely used retention enema method was to retain for 15 minutes and administer twice a day for 3 days. In most of the studies, retention enema with herbal medicine in pediatric diarrhea showed significant efficacies. No adverse effects were reported from the studies. Conclusions The results of these studies from China showed that the retention enema with herbal medicine in pediatric diarrhea may be effective and safe.

• 대한한방소아과학회지
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• 제35권1호
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• pp.48-62
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• 2021

Objectives The purpose of this study is to obtain knowledge from clinical studies conducted in China to examine the effectiveness of herb medicine in childhood acute leukemia. Methods We searched the randomized controlled trials (RCTs) with herbal medicine treatment on childhood acute leukemia from the 'CAJ', Chinese Academic Journal from China National Knowledge Infrastructure (CNKI). And then, demographic data, duration of illness, intervention, treatment period, outcome, adverse events, and composition of herbal medicine were analyzed for this study. Result 10 RCT studies were selected and analyzed. The control group were given western medicine therapy, the treatment group was given herbal medicine on the basis of the control group. The most commonly used herbal medicine were 淸熱解毒藥, 補氣藥, 補陰藥, 活血祛瘀藥 in 'boosting vital force and driving out evil spirit (扶正祛邪)' way to 'relieve heat (熱毒)' and 'assist the vital force (正氣)'. In the treatment group, complete remission was significantly higher than control group and the decrease in TCM syndrome scores also showed significant effects. Adverse events were significantly lower in the treatment group. Conclusions Herbal medicine treatment on childhood acute leukemia can be suggested as a new treatment for children who have less response to the conventional therapy, and can supplement the limitations of the western medicine by increasing complete remission and reducing adverse events.

• 한방안이비인후피부과학회지
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• 제37권1호
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• pp.57-68
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• 2024

Objectives : The purpose of this study is to analyze the current trends of various herbal medicine research on allergic disease with dysbiosis. Methods : Electronic searches were performed using Pubmed, Research Information Sharing Service(RISS), Korean studies Information Service System(KISS), Oriental medicine Advanced Searching Integrated System(OASIS). Results : We analyzed ten studies on the effect of herbal medicine on allergic disease with dysbiosis. Eight studies were animal experimental studies, and two were randomized clinical trial(RCT) study and one-group pretest-posttest research, respectively. Among the studies, three studies were on atopic dermatitis, two on allergic rhinitis, and five on asthma. All different herbal medicines were used in the studies. Changes in gut microbiota composition were observed in nine studies except for 1 RCT study. In eight animal experimental studies, there was significant reduction in allergy-related inflammatory markers. Six studies evaluated the change of metabolites related to gut microbiota and three of them showed significant increase in short-chain fatty acids(SCFA). Conclusion : This study provides current trends of studies on herbal medicine research on allergic disease with dysbiosis. Most research is conducted using animal experiments, and this is a relatively recent trend. These studies offer basic knowledge on the correlation between herbal medicine, gut microbiota, and anti-inflammatory effects in allergic disease.