• 디지털융복합연구
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• 제13권7호
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• pp.269-282
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• 2015

본 연구는 혈액여과투석 환자의 치료이행을 측정할 수 있는 지표와 분류기준을 개발하고 치료이행 정도를 측정할 수 있는 전문가의 의견이 반영된 융합형 도구를 개발하고자 시도되었다. 총 300명의 혈액여과투석 환자를 대상으로 자료가 수집되었으며, 저유량 혈액투석, 고유량 혈액투석 치료이행과 불이행에 대한 선행연구 결과 및 전문가 그룹, 임상전문가 그룹의 구성타당도, 내용타당도를 거쳐 혈액여과투석 지표와 분류기준을 개발하였다. 개발된 혈액여과투석 치료이행 지표와 분류기준의 판별분석력을 정준상관판별분석으로 검증한 결과 3가지 지표의 혈액여과투석 치료이행 판별분석력은 95.6%(wilks ramda=.256, p=.002)이었다. 또한 임상형 혈액여과투석 치료이행 측정도구는 91.7%의 판별력을 가진 것으로 검증되었다. 혈액여과투석 치료이행은 환자의 건강상태 악화와 합병증 발생 전 단계에서 환자교육과 간호중재가 이루어질 수 있다는 점에서 의미가 있으며 본 연구의 결과는 향후 혈액투석환자의 합병증 예방을 위한 간호중재의 기초자료로 활용될 수 있을 것이다.

• 전자공학회논문지B
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• 제30B권11호
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• pp.47-55
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• 1993

This paper is to design an autobalancing system based-on microprocessor for hemodiafiltration (HDF) system. The proposed system consist of motor control part, thermostatic control part, alarm system and electronic scale which ar automatically controlled by microprocessor. Conventional hemodialysis system can not remove medium molecular articles but hemodialysis system with the proposed system can remove and infuse substitute to the patient. This system can be easily interfaced with any other conventional HD system. The results obtained from performance evaluation of the proposed system are suitable for clinical supporting system.

• Childhood Kidney Diseases
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• 제7권1호
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• pp.96-102
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• 2003

저자들은 methymalonic acidemia로 진단된 체중 2.4 kg의 생후 5일된 여아에서 지속적 정정맥 투석 여과법(CVVHDF)을 이용하여 혈역학적 불안정 상태나 특별한 후유증 없이 체내 암모니아를 효과적으로 제거하였기에 보고하는 바이다.

• 대한의생명과학회지
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• 제25권1호
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• pp.32-39
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• 2019

Conventional high-flux hemodialysis (HD) is not as good as normal kidney function. Morbidity and mortality rates of patients receiving HD are still very high. To increase mid-to-large molecule clearance by combining diffusion and convection, on-line hemodiafiltration (HDF) is required. The objective of this study was to compare long-term survival rate of patients treated with on-line HDF to those who received conventional high-flux HD by reviewing data from Chonnam National University Hospital (CNUH). We selected patients who attended the 'CUNH dialysis center' and agreed to participate in the study. Overall, 40 patients with ESRD switched from high flux HD to on-line HDF or started on-line HDF from August 2007 to December 2009. Additionally, a total of 42 patients receiving conventional high-flux HD during the same period were enrolled. We then reviewed long-term survival rate of patients receiving on-line HDF over the next seven years. When we compared survival rates for seven years, the survival rate of the group receiving on-line HDF was 65% (26/40) while that of the group receiving the conventional high-flux HD was 54.8% (23/42). Although the number of patients was small to see survival difference clearly by one specific dialysis modality, there was somewhat difference in survival rate between the two groups. Indicators such as anemia, calcium-phosphate metabolism, nutritional status, treatment adequacy, and hospitalization were also improved in the group receiving HDF. Overall, results of our study showed beneficial effects of on-line HDF on clinical outcomes and survival in chronic HD patients.

• 대한기계학회:학술대회논문집
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• 대한기계학회 2008년도 추계학술대회A
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• pp.1655-1659
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• 2008

Using numerical models, we investigated the efficiency of toxin removal using pulsatile flow in blood purification systems that use semipermeable membranes. The model consisted of a three-compartmental mass transfer model for the inside body and a solute kinetics model for the dialyzer. The model predicted the toxin concentration inside the body during blood purification therapy, and the toxin removal efficiencies at different flow configurations were compared quantitatively. According to the simulation results, the clearances of urea and ${\beta}_2$ microglobulin (B2M) using a pulsatile pump were improved by up to 30.9% for hemofiltration, with a 2.0% higher urea clearance and 4.6% higher B2M clearance for high flux dialysis, and a 3.9% higher urea clearance and 8.2% higher B2M clearance for hemodiafiltration. These results suggest that using a pulsatile blood pump in blood purification systems with a semipermeable membrane improves the efficacy of toxin removal, especially for large molecules and hemofiltration treatment.

• 대한임상독성학회지
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• 제11권1호
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• pp.28-30
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• 2013

A 66-year-old male with chronic alcoholism presented with tremor, gait disturbance, memory impairment, insomnia, decreased appetite, and confusion. The patient had been taking lithium daily for treatment of bipolar disorder. Brain CT showed no specific abnormality, and serum lithium and ammonia levels were 3.63 mEq/L (therapeutic range, 0.6~1.2 mEq/L) and $85{\mu}g/dL$ (reference range: $19{\sim}54{\mu}g/dL$), respectively. Therefore, the initial differential diagnosis included chronic lithium intoxication, hepatic encephalopathy, Wernicke encephalopathy, or alcohol withdrawal syndrome. Even with the provision of adequate hydration, the patient's neurologic status did not show improvement, so that lactulose enema, thiamine replacement, and continuous venovenous hemodiafiltration (CVVHDF) were started on the third admission day. By the fifth admission day he had made a rapid neurologic recovery, and was discharged on the 20th admission day. Therefore, CVVHDF might be a treatment for patients with chronic lithium intoxication, because, even if serum lithium concentration is normal, lithium concentration in the brain may be different from that of the serum.

• Journal of Chest Surgery
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• 제55권1호
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• pp.81-84
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• 2022

Esophagectomy and esophageal reconstruction are commonly chosen as surgical options for esophageal cancer. However, prolonged untreated chyle leakage is associated with a poor prognosis. We report the case of a patient with refractory chylous ascites. To limit the ongoing fluid loss, we utilized the chylous ascites as an additional fluid source in a renal replacement therapy system. A continuous renal replacement therapy (CRRT) drainage system was modified to drain both the chylous ascites and venous blood. The ascites drainage rate was determined empirically and regulated by a dial-flow extension set. The CRRT mode was set to continuous venovenous hemodiafiltration and maintained for 7 days. After the patient was weaned from CRRT, ascites did not reaccumulate, and the patient's general condition improved dramatically. No infections related to the system occurred. This procedure temporarily alleviates symptoms and provides more time for alternative treatment strategies.

• 대한의용생체공학회:의공학회지
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• 제14권3호
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• pp.221-226
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• 1993

Modules of hemodiafilter were manufactured by using MC-Hp200 and RC-HP4DOA hoi low fiber membranes of Enka Co. in a unique design. The performances of she hemodiafillers were evaluated by measuring the molecular weight cut-off, ultrafiltration rate, clearance, and pressure drop across the hemodiafiter. As a whole, the performances of the RC-HP400A module were superior to those of the MC-Hp200 module. The modules prepared in thls study showed the satisfactory performances for hemodiafiltration.

• 재활간호학회지
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• 제17권1호
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• pp.27-37
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• 2014

Purpose: The purpose of this study was to understand nurses' experience of managing diet and fluid in hemodialysis patients and to provide helpful information in improving care of hemodialysis patients. Methods: Data were collected through in-depth interviews with ten nurses who had experience of providing care to hemodialysis patients. Colazzi's phenomenological method was used to analyze data. Results: Twenty themes were identified in the first stage of data analysis and were later categorized into ten theme clusters, of which four categories were derived. The four categories were 'developing a strong feeling of responsibility for management', 'acknowledging limits in performing duties', 'providing patient-centered education' and 'becoming a guide for the long treatment process'. Conclusion: The study results will be useful for improving nursing curriculum to ensure more effective and successful diet and fluid management in hemodialysis patients.

• 대한의용생체공학회:의공학회지
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• 제5권1호
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• pp.9-14
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• 1984

The asymptotic solution using the Tailor series has been given explicit form for the solute concentration and overall solute removal in hemodiafilter using one dimensional model. The numerical solutions have been calculated within 0.001% error by the Romberg integration method. Compared with the numerical solutions, the oneterm asymptotic solutions were found to be within 3% error for the condition > 3.0 and three-terms asymtotic solutions were required for the condition >0.7 where denotes measure of convection over diffusional transport and a the ratio of blood flow rate over dialysate flow rate.