• Journal of the Korean Magnetic Resonance Society
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• v.12 no.1
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• pp.40-50
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• 2008

Ghrelin is a unique peptide hormone that releases growth factor and it stimulates appetite. It comes from pre pro-ghrelin by the post translational modification process and its innate functions are known as food up-take and the growth hormone regulation. Therefore, the structural information of ghrelin precursor is of importance in understanding it function. From our results, we found that the solution structure of ghrelin is mostly random coil conformation at neutral pH value and the structural population changes with pH environments. Data from circular dichroism in different TFE concentrations revealed that the secondary structure changes from random coil to a-helix and the isodichroic point is observed at 202nm, implying that two equilibrium states exist between random coil and helical structure.

• Journal of the Korean Chemical Society
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• v.39 no.10
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• pp.776-782
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• 1995

A theory of the helix/coil transition for $\alpha$ helical dimer such as $\alpha$ tropomycin and paramycin is developed. The treatment differs from those formulated previously for oligopeptide dimer which is explained by the matrix method using Zimm-Bragg parameter: In the present treatement, it is explained by the zipper model which can account for the dangling H-bond. We calculate the fractional helicity in $\alpha$ helical dimer as a function of helix initiation $constant(\sigma)$, helix stability constant(${\xi}$) and hydrophobic interaction parameter(w). For $\alpha$ tropomycin, the helix stability profile is also calculated. The transitions of this oligomer due to the change of temperature and the concentration of oligopeptide involve simultaneous dissociation of the dimer. The transitions of dimers which have cross-linked S-S bonds or have long chains don't occur, because they keep always helical structures. The transitons due to the concentration of the oligopeptides are steeper than those due to the chain length or temperature.

• Nuclear Engineering and Technology
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• v.52 no.12
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• pp.2699-2708
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• 2020

Helical-coil steam generator (HCSG) technology is a major design candidate for small modular reactors due to its compactness and capability to produce superheated steam with high generation efficiency. In this paper, we investigate the feasibility of the passively autonomous power maneuvering by coupling the 3-D transient multi-physics of a soluble-boron-free (SBF) core with a time-dependent HCSG model. The predictor corrector quasi-static method was used to reduce the cost of the transient 3-D neutronic solution. In the numerical system simulations, the feedwater flow rate to the secondary of the HCSGs is adjusted to extract the demanded power from the primary loop. This varies the coolant temperature at the inlet of the SBF core, which governs the passively autonomous power maneuvering due to the strongly negative coolant reactivity feedback. Here, we simulate a 100-50-100 load-follow operation with a 5%/minute power ramping speed to investigate the feasibility of the passively autonomous load-follow in a 450 MW_th SBF PWR. In addition, the passively autonomous frequency control operation is investigated. The various system models are coupled, and they are solved by an in-house Fortran-95 code. The results of this work demonstrate constant steam temperature in the secondary side and limited variation of the primary coolant temperature. Meanwhile, the variations of the core axial shape index and the core power peaking are sufficiently small.

• The korean journal of orthodontics
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• v.21 no.2 s.34
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• pp.353-366
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• 1991

This study was performed to analyze the effects of forces to the alveolar bone by various molar uprighting spring such as helical uprighting spring. T-loop spring, Modified T-loop spring and open coil spring. The simplified two-dimensional photoelastic model was constructed with a lower left posterior quadrant containing the second molar, the first and second premolars and the canine, with the first molar missing. Several molar uprighting springs were fabricated from 0.017 by 0.022 inch blue Elgiloy and applied to the photoelastic model. Two-dimensional photoelastic stress analysis was performed, and the stress distribution was recorded by photography The results obtained were as follows; 1. In all the kinds of the springs, the center of rotation of the mandibular second molar was oserved at the apical 1/5-1/6 between the alveolar crest and the root apex. 2. In all the kinds of the spring, the stress induced in the mesial root surface of the mandibular second molar was relatively homogeneous but there was some difference in the magnitude of the stress. 3. In the kinds of the springs, the distal crown tipping moment of the second molar was increased in turn as open coil spring, helical uprighting spring, T-loop spring, and modified T-loop spring. 4. The largest extrusive force was occured in the T-loop spring, intrusive force was occured in Modified T-loop spring only, and the largest distal tipping force was occured in open coil spring. 5. In the T-loop spring with activation, the stress induced in the mesial root surface of the second molar was increased gradually from the root apex to the alveolar crest and highly concentrated in the alveolar crest.

• Journal of the Korean Society of Propulsion Engineers
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• v.24 no.3
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• pp.59-70
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• 2020

Obtaining external forced convection heat transfer from bubble boiling and validating it with experimental results using cryogenic liquids are suggested to derive total heat transfer coefficient with pool boiling condition in the case of coil type heat exchanger with a bundle of tubes and to overcome the limitation of using the empirical correlation. Experiment is conducted with pool boiling heat transfer of saturate liquid nitrogen with helical coil type heat exchanger using liquid oxygen as hot stream fluid. Experimentally measured heat transfer coefficient is well-agreed with the estimated curve considering nucleate boiling and forced convection induced by bubble rise.

• Nuclear Engineering and Technology
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• v.49 no.8
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• pp.1669-1679
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• 2017

Background: Steam generator (SG) is one of the significant components in the nuclear steam supply system. A variety of SGs have been designed and used in nuclear reactor systems. Every SG has advantages and disadvantages. A brief account of some of the existing SG designs is presented in this study. A high surface to volume ratio of a SG is required in small modular reactors to occupy the least space. In this paper, performance improvement for SGs of integral small modular reactor is proposed. Aims/Methods: For this purpose, cross-grooved microfins have been incorporated on the inner surface of the helical tube to enhance heat transfer. The primary objective of this work is to investigate thermal-hydraulic behavior of the proposed improvements through modeling in RELAP5-3D. Results and Conclusions: The results are compared with helical-coiled SGs being used in IRIS (International Reactor Innovative and Secure). The results show that the tube length reduces up to 11.56% keeping thermal and hydraulic conditions fixed. In the case of fixed size, the steam outlet temperature increases from 590.1 K to 597.0 K and the capability of power transfer from primary to secondary also increases. However, these advantages are associated with some extra pressure drop, which has to be compensated.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.22 no.10
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• pp.999-1004
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• 2011

In this paper, calculation method of mutual inductance for two circular coils which are widely used in wireless power transfer system and analysis results using the method are proposed. Two circular coils are arranged in a perpendicular way. For calculation of the mutual inductance, an Rx coil placed perpendicularly with the other coil is uniformly subdivided into many unit cells and both magnetic flux density linked with the Rx coil at each unit cell and the total magnetic flux density of the Rx coil are obtained. Two circular coils are considered as a filamentary coil and uniform current density on each coil is assumed. For verification, helical and spiral coils are fabricated. As a result of measurement in 50 cm to 100 cm distance, theoretical mutual inductance is almost agreed with measured one.

• Proceedings of the SAREK Conference
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• 2007.06a
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• pp.12-12
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• 2007

• Bulletin of the Korean Chemical Society
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• v.17 no.2
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• pp.131-138
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• 1996

The conformational transition of oligopeptide multimer,-(HPPHPPP)n-, is studied (H:hydrophobic amino acid, P:hydrophilic amino acid). The helix/coil transitions are detected in the multimer. The transition depends on the number of amino acid in the sequence, the concentration of the oligopeptide, and temperature which affects helix stability constant (${\xi}$) and hydrophobic interaction parameter (wj). In the thermodynamic equilibrium system jA${\rightarrow}$Aj (where A stands for oligopeptide monomer), Skolnick et al., explained helix/coil transition of dimer by the matrix method using Zimm-Bragg parameters ${\xi}$ and $\sigma$ (helix initiation constant). But the matrix method do not fully explain dangling H-bond effects which are important in oligopeptide systems. In this study we propose a general theory of conformational transitions of oligopeptides in which dimer, trimer, or higher multimer coexists. The partition of trimer is derived by using zipper model which account for dangling H-bond effects. The transitions of multimers which have cross-linked S-S bonds or long chains do not occur, because they keep always helical structures. The transitions due to the concentration of the oligopeptides are steeper than those due to the chain length or temperature.

• Journal of Sensor Science and Technology
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• v.8 no.4
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• pp.298-307
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• 1999

This paper describes the application of the coupled FE-BEM (finite element-boundary element method) for the numerical harmonic analysis of the linear dynamic behaviour of a magnetostrictive Terfenol-D rod in water. The magnetostrictive rod is three-dimensionally simulated to transduce applied electric current in a helical coil around the rod to mechanical displacement. The theoretical derivation of the magnetostrictive matrix equation is described in detail. The steady-state resonance response of the displacement is shown. In addition, the directivity pattern and the radiation impedance are also shown.