• 한국노년학
• /
• v.32 no.4
• /
• pp.1101-1118
• /
• 2012

The purpose of this study is to examine which factors determine self-rated health(SRH) among Korean elderly focusing on gender differences. To achieve this purpose, it uses the Hallym Longitudinal Study of Aging, wave 4 in 2009. Participants aged 65 and over from wave 4 were selected(N=986, male 407, female 579). From wave 4, all variables were selected except for respondents' education which was from wave1. In analyses, $x^2$ or t-test were conducted to examine whether independent variables significantly differ by SRH. Then, since a dependent variable consisted of two categories-being healthy or not being healthy, logistic regressions were run. What makes gender differences in the link of independent variables to SRH were 75-84 age group, education, and IADLs. For females, 75-84 age group rated their health as worse compared to 65-74 age group, but this age group did not have significant effect on SRH for males. Females graduating from junior high school were more likely to higher rate their health compared to their counterparts. However, education was not significant for males. Instrumental activities of daily living(IADLs) is one of variables affecting SRH by making gender differences. Female having problems with IADLs were more likely to be significantly negatively rate their health compared to males. Through focusing on age, education, IADLs making gender difference in evaluating health, governments needs to support males and females differently.

• 한국노년학
• /
• v.40 no.4
• /
• pp.617-638
• /
• 2020

It is important to maintain a healthy dietary habit to enjoy better health and quality of life in later life. However, taking care of one's dietary lifestyle at an older age may be a challenge. Especially, community dwelling low-income older adults are one of the most vulnerable population in regards to holding a well balanced healthy diet. The purpose of this research is to identify the current status of food delivery services for low-income older adults and explore related issues. In order to achieve the aim, this study conduced two sets of focus group interviews with 8 nutritionists and 7 social workers in Seoul. According to the research results, there are issues related to meals on wheels such as vague eligibility, poor operation conditions, work overload, and difficulty in realizing customized meal delivery. Food security for low-income older adults is a prerequisite for aging in place. It is necessary to discuss the ways to create favorable operating conditions to deliver customized meals and manage nutrition and hygiene from the perspective of social work.

• Korean Journal of Acupuncture
• /
• v.40 no.3
• /
• pp.90-98
• /
• 2023

Objectives : Parkinson's disease (PD) is the second most common neurodegenerative disorder worldwide and is characterized by the loss of the dopaminergic neurons in the substantia nigra (SN). In a previous in vitro study, we demonstrated that Sihogyeji-tang (SG), Sihosogan-tang (SS), and Sihocheonggan-tang (SC) have the potential to be candidate medicines for PD. This study aimed to compare the neuroprotective effect of SG, SS, and SC using 1-methyl-4-phenyl-1,2,3,6-tetrahydrophridine (MPTP)-induced PD mouse model. Methods : Eight-week-old male C57BL/6 mice were intraperitoneally administered with 30 mg/kg of MPTP for 5 days and orally administered SG, SS and SC for 12 days from the first MPTP injection. Motor function was assessed using the pole test and the rotarod test. Dopaminergic neuronal survival in the SN and striatum was evaluated through tyrosine-hydroxylase immunohistochemistry. Results : MPTP administration resulted in behavioral impairment and dopaminergic neuronal death in the SN and striatum. In the pole test, treatment with SG, SS, and SC alleviated the MPTP-induced motor dysfunction on day 5 and 12. In the rotarod test, SS and SG alleviated the MPTP-induced motor dysfunction on day 5, while only SS showed improvement on day 12. SS and SG significantly protected dopaminergic neurons in the SN from MPTP toxicity, and all three compounds (SG, SS, and SC) showed significant protection in the striatum. Notably, SS demonstrated superior efficacy in suppressing MPTP-induced motor dysfunction and dopaminergic neuronal death compared to SG and SC. Conclusions : These findings suggest that SS is the most effective formula among SG, SS, and SC for PD, indicating its potential role in the treatment of PD.

• The Journal of Korean Medicine
• /
• v.23 no.3
• /
• pp.1-10
• /
• 2002

Objective: There exist gender differences in pulsatile contour waveform. Women have a greater age-related increase in left ventricular mass than do men and more likely to experience symptomatic heart failure after infarction. SDPTG (the second derivative of photoplethysmogram waveform) is a noninvasive method for evaluating the pulse wave and is correlated with age and other risk factors for atherosclerosis. We studied the effect of gender on SDPTG and made clear why the gender differences appear. Methods: To study the effects of effect factors, including height and blood pressure, on SDPTG in the fourth decade, data on height, weight, PTD (pulse transit distance), blood pressure, serum lipid levels, and SDPTG were collected in 115 laboratory healthy men and women. SDPTG is derived from double-differential processing of fingertip photoplethysmography and consists of a, b, c, and d waves in systole and an e wave in diastole; SDPTG aging index (AI) was calculated as (b-c-d-e)/a. Results: There were significant gender-related differences of SDPTG AI, height, and blood pressure. Age, height, and mean blood pressure were respectively and significantly correlated with SDPTG AI. SDPTG is dependent upon age, height, and blood pressure. Restricting analysis to SDPTG AI, age, height, and mean blood pressure, yielded that there were gender-related differences in SDPTG AI (P<0.05) which were derived from those of height (F<0.001, df=l, P=0.994). Conclusions: These new data may help to explain previous findings about age-related differences in pulsatile contour waveforms and why gender differences of SDPTG appear. The results of this study suggest that SDPTG AI, used for evaluation of biological vascular aging, should be calibrated by height as well as age and blood pressure.

• The Journal of Korean Medicine
• /
• v.35 no.3
• /
• pp.155-165
• /
• 2014

Objectives: The pulse diagnosis to identify the symptoms has been considered important in Korean medicine. The position and character of disease would be confirmed by pulse diagnosis of left and right radial artery. This paper is to analyze the characteristics and differences of left and right blood vessels. Methods: In this study, left and right radial artery and dorsalis pedis artery was measured and analyzed by using condenser typed pulse analyzer. Commercially available pulse analyzer was used to measure the radial artery. The pulse wave was measured in 20 laboratory healthy men and women. The blood vessel aging degree and index of augmentation of blood vessel was obtained from the measured pulse wave graph and the characteristics and differences of the left and right blood vessel was analyzed. Results: The significant difference of pulse transit time between the right handed and non-right handed was not found. The correlation of radial artery and dorsalis pedis artery had no significant difference. By obtaining the blood vessel aging index (AGI) and augmentation index (AI) of blood vessel at the left and right radial artery, the significant difference between right handed and non-right handed was not found. Conclusions: The result of this study would help to explain the characteristic of blood vessel with respect to the left and right handed. We suggest that research of pulse wave of the left and right blood vessel using pulse analyzer should be needed in further study.

• The Korean Journal of Food And Nutrition
• /
• v.33 no.1
• /
• pp.17-26
• /
• 2020

This study was conducted to evaluate the functionality of fermented black garlic extracts under various conditions. Black garlic powder was prepared by aging for 0~72 hours at 80℃ depending on relative humidity (RH). It showed the highest antioxidant effects among the samples; the total antioxidant activity of black garlic powders at RH 75%, 84%, and 90% for 72 hours was increased 31.9 times, 28.2 times, and 22.6 times compared with that of the fresh garlic powder, respectively. Also, the alliin content was gradually decreased. S-ally-L-cysteine and S-ethyl-cysteine levels were increased; the highest values were 495.9 ㎍/g and 1,769.7 ㎍/g after aging for 72 hours at RH 75%. Aspartate transaminase (AST) and alanine transaminase (ALT) levels were increased following high fat diet feeding, but the rise was obviously reduced by administration of black garlic extract. The total cholesterol, LDL/VLDL-cholesterol, and triglyceride contents in serum were significantly lower in methionine and choline deficient (MCD) diet treatment groups than in the positive control group. The concentration was increased following the intake of black garlic and fermented black garlic extracts. Therefore, black garlic extracts could be an ideal material as a dietary supplement in healthy functional foods to improve the effects on fatty liver.

• Korean Journal of Community Nutrition
• /
• v.5 no.1
• /
• pp.109-119
• /
• 2000

The purpose of this study was to measure serum lipids concentrations by gender and age, and to investigated the relation of serum lipids levels to cigarette smoking alcohol intake exercise and menopausal status in Korean adults. The subjects consisted of 463 healthy adult(29- men and 173 women) volunteers who were visiting the health Promotion Center in the Asan Medical Center from July 1, 1994 to July 22, 1994 Subjects were ambulatory free-living people and aged 20- 80 years, Anthropometric measurement was performed and serum triglyceride(TG), HDL-cholesterol and total cholesterol(TChol) concentrations were measure by automatic system(Hitachi 736-40). Data on life styles were obtained using structured questionnaires issued by a trained interviewer, All data were statistically analyzed by PC-SAS(Version 6.04) Serum concentrations of triglyceride and total cholesterol was higher(p<0.05) in men than in women, and serum HDL-cholesterol was lower(p<0.05) in men than in women. The prevalence of hyperlipidemia(TG>170 mg/dL and TChol>220 mg /dL) was 12.5% in men and 4.1% in women. The levels of serum triglyceride, total cholesterol and BMI increased with age in women. The distribution curves of serum triglyceride, total cholesterol and LDL-cholesterol of women were located in lower increased more rapidly with aging than in men, The distribution curves of BMI of women increased with aging after the thirties, The BMI of women was located in higher levels than of men in their sixties. The serum concentration of triglyceride and total cholesterol of male current-smokers and non- smokers were significantly(p<0.05) higher than those of ex-smokers. The concentrations triglyceride the male current0drinkers were higher(p<0.05) than those of male non-drinkers. In non-smokers and non- drinkers, serum TG concentration were lower (p<0.05) than those of current-smokers and current-drinkers. In exercisers, the serum triglyceride concentration was significantly(p<0.05) lower than in non- exercisers. In postmenopausal woman BMI and serum concentrations of TChol, TG and LDL-Chol were significantly by age and gender and smoking alcohol drinking, exercise and menopausal staus might be a better indicator to predict serum lipids in both genders.

• Korean Journal of Human Ecology
• /
• v.18 no.5
• /
• pp.995-1008
• /
• 2009

This study investigated the causal relationships among the elderly, looking at social participation, depression, self-reported health, and life satisfaction. It was especially focused on the mediating effects of depression and self-reported health on the relationship between social participation and life satisfaction. From the 2006 Korean Longitudinal Study of Aging, data for 4,155 elderly over age 65 was analyzed with structural equations modeling with Amos 7.0 and sobel test. Major findings were as follows. First, social participation of the elderly has a negative influence on depression and a positive influence on self-reported health and life satisfaction. Second, self-reported health has a partial mediating effect on the relationship between social participation and life satisfaction. Third, the direct effect of depression on life satisfaction was not statistically significant, while the direct effect of social participation was significant. Therefore, depression was not proved as a significant mediator. This study tested the effects of social participation on depression, self-reported health, and life satisfaction empirically and confirmed the partial mediating model, in which social participation improves the elderly's self-reported health, which in turn improves the elderly's life satisfaction. These results suggest the importance of an integrated approach for the healthy and successful aging and the diverse types of social participation in an elderly person's quality of life.

• Asian Pacific Journal of Cancer Prevention
• /
• v.13 no.10
• /
• pp.5229-5232
• /
• 2012

The incidence of malignant melanoma increases with age. One significiant effect of aging processes is an accumulation of oxidative damage in the genetical material. In this study, the relationship between malignant melanoma and damage in chromosomes and proliferative effectiveness of human peripheral lymphocytes were investigated by the micronucleus (MN) technique. A total of 15 malignant melanoma patients and appropriately matching 15 healthy controls were involved in the study. MN frequencies and proliferative indexes (PI) after non toxic levels of hydrogen peroxide treatment were also measured to determine damaging effect of oxidative stress in genome in addition to measuring the spontenous levels of micronuclei and PI. The patient group had a significantly higher rate of spontaneous MN than the control group (p<0.01). After treatment with $H_2O_2$, MN frequencies in the patient group was significantly decreased (p<0.01) although there was no difference between the treated and untreated results of control group (p=0.29). There was also difference (p<0.01) between the MN frequencies of the patient and the control group either in the spontaneous levels or in the $H_2O_2$ treated groups. The same significant difference persisted when the PI values were compared between patient and control groups. Increase in the MN frequency in patients could mean the alterations in the chromosomal structure which may lead to the chromosome instability and therefore genetic susceptibility to cancer. This increased number of micronuclei can also be used for cytological marker in identifying high risk cases for malignant melanoma.

• Journal of the Society of Disaster Information
• /
• v.10 no.3
• /
• pp.466-480
• /
• 2014

In addition to aging social problem, the problem of older age structure ratio in the fire service organization playing the leading role of the disaster response activities is also expected to be this serious situation. In the case of Seoul fire fighting organization, it is expected that the ratio of over the age 50 reaches 31% or 40% between from 10 to 15 years later from now on, but this will be a serious problem in the fire fighting personnel needing a healthy body and physical strength in the disaster situation unlike the civil servants of general staff. Therefore, the purpose of this study is to take measures that can adapt to a new disaster environment of Increasing proportion of the elderly population by presenting the criteria of age limit of fire fighting field activities to analyze the relevance of the ability to perform on-site activities and age of Seoul fire civil servants, by using three analysis criteria.