• Title/Summary/Keyword: Health research and development

Search Result 5,060, Processing Time 0.042 seconds

Effects of Jerusalem Artichoke (Helianthus tuberosus L.) Extracts on Blood Glucose and Lipid Metabolism in STZ-induced Diabetic Rats (돼지감자 추출액이 Streptozotocin으로 유발된 당뇨쥐에서 혈당 및 지질대사에 미치는 효과)

  • Kim, Hye-Jeong;Kim, Dong-Il;Yon, Jung-Min
    • Korean Journal of Clinical Laboratory Science
    • /
    • v.47 no.4
    • /
    • pp.203-208
    • /
    • 2015
  • This study investigated the effect of Jerusalem artichoke (Helianthus tuberosus L.) extract on Blood Glucose and Lipid Metabolism in Streptozotocin (70 mg/kg B.W., i.p.)-induced Diabetic Rats. Sprague-Dawley male rats (200~220 g) were divided into normal control group (NC), diabetic control group (DC) and Jerusalem artichoke treated diabetic group (DJ). Diabetes was induced by single intraperitoneal injection of streptozotocin as a dose of 70 mg/kg body weight. Food (p<0.001) and water (p<0.05) intakes were higher in diabetic groups than the normal group. Body weight gain and food efficiency ratio were significantly lower in diabetic groups than normal group (p<0.01). However, they were higher in the DJ group than in the DC group. The serum levels of AST and ALT were significantly lower in the DJ group than in the DC group (p<0.05). The serum level of HDL-C was significantly higher in the DJ group than in the DC group (p<0.001). The serum levels of Triglyceride (p<0.05), LDL-C (p<0.001), and glucose (p<0.001) were significantly lower in the DJ group than in the DC group. At 3 and 4 weeks after the experiment, blood glucose level in the DJ group was significantly lower than the DC group (p<0.05). In conclusion, these results indicated that Jerusalem artichoke can prevent or retard the development of diabetic complications via its beneficial effects for alleviating the hyperglycemia and improved lipid metabolism.

The Effects of Characteristic and Social Support on the Life Satisfaction of the Elderly (노인의 일반적 특성과 사회적 지지가 생활만족도에 미치는 영향)

  • Kang, Young Sook;Jung, Jayoung
    • Asia-Pacific Journal of Business Venturing and Entrepreneurship
    • /
    • v.15 no.1
    • /
    • pp.259-268
    • /
    • 2020
  • The purpose of this research is to investigate the determinants of life satisfaction and social support among the elderly. For this purpose, a set of characteristic factors that are supposed to affect elderly life satisfaction were suggested and empirically analyzed. To achieve this study used final analysis with 470 questionnaires which did a questionnaire survey after gathering purposeful sampling method of 500 person who were visiting on Senior Club and Senior Welfare Center. The collected data were analyzed by using the SPSS statistical program. The methods of analysis were frequency, factor analysis, and regression analysis. The results of this study are as follows. Firstly, characteristic factors such as the family relation, health and economic of the elderly have significant impacts on their life satisfaction. Secondly, it was seen that social support regulated the effects of family relation and economic on characteristic factors. The implications of this study are, above all, to build a human network for training, education and social support for career development while participating in the labor market. Such activities could lead to social support for economic independence in old age.

A Teratogenicity Study on Dimethyl Dimethoxy Biphenylate Derivative (DDB-S) in Rats (염산 DDB-S가 랫드의 생식독성에 미치는 영향에 관한 연구)

  • Kim, Hyun-Woo;Park, Jin-Hong;Moon, Seo-Hyun;Eu, Gook-Jong;Kim, Hwa;Kim, Joon-Seong;Park, Jong-Ha;Cho, Hyun-Sun;Kang, Ka-Mi;Hwang, Seong-Hee;Kim, Pan-Gyi;Moon, Jeon-Ok;Lee, Chi-Ho;Cho, Maing-Haing
    • Toxicological Research
    • /
    • v.19 no.1
    • /
    • pp.21-27
    • /
    • 2003
  • A teratogenic study of dimethyl dimethoxy biphenylate derivative (DDB-S) was carried out on Sprague-Dawley rats. DDB-S dissolved in saline was administered to male and female rats by intravenously injection at daily doses of 50 mg/kg, 75 mg/kg, and 100 mg/kg. A half of dams were sacrificed at 20th day of gestation to scrutinize the pregnant performances and fetal development. And the remaining dams were allowed to deliver. The growth, reflex, behaviour and reproductive function of F1 offsprings were examined. There was no treatment-related difference in body weight, food consumption and necropsy findings of dams. No gross, skeletal and visceral abnormalities was observed in F1 fetuses from dams treated with DDB-S. F1 offsprings did not show any treatment-related difference in growth, reflex, behaviour and reproductive performance. At caesarean section of F1 dams, no growth retardation and gross abnormality was observed in F2 fetuses. In conclusion, DDB-S did not show any potential teratogenic effect in rats.

Changes in Residual Nitrite, TBARS and Color of Meat Products during Storage (육제품의 저장 중 아질산이온 잔류량, TBARS 함량과 육색의 변화)

  • Kim, Gi-Suk;Choi, Seong-Hee
    • Food Science of Animal Resources
    • /
    • v.27 no.3
    • /
    • pp.299-307
    • /
    • 2007
  • Changes in nitrite content, TBARS content and color of meat products during storage were examined as part of studies addressing the reduction of residual nitrite and to ensure the safety of meat products. All 4 kinds of domestic meat product tested, Vienna sausage, bacon, smoked-ham and Dduggalbi, manufactured by C and L domestic companies had very low contents of residual nitrite, for below the legal tolerance limit of 70 ppm, and the residual nitrite decreased with storage. The reduction in nitrite content differed with each product, showing the greatest reduction in Vienna sausage and the least reduction in bacon when stored at $4^{\circ}C$. On the other hand, when stored at $-20^{\circ}C$, the nitrite content of bacon decreased more rapidly than the other meat products. The results of this study show that the nitrite content of meat products decreases during storage, and that the rate of decrease is quite dependent on the storage temperature. In addition, the nitrite contents of most domestic meat products are very low compared to the legal limits, thus the health risks of nitrite in meat products might not be of great concern. More research on the reduction of residual nitrite and on the development of alternatives to nitrite is necessary.

Content analysis of the way university students appreciate the meaning of life (대학생이 인식하는 삶의 의미에 대한 내용분석)

  • Park, Bock-Soon;Choi, Eun-Young;Park, Sang-Yong;Park, Sun-Jung
    • Journal of the Korea Academia-Industrial cooperation Society
    • /
    • v.17 no.4
    • /
    • pp.160-171
    • /
    • 2016
  • The purpose of this study is to understand the way university students appreciate the meaning of life. The subjects were 1, 2, 3, and 4 grade students from four universities located in Gyeonggido and Gangwondo Provinces; This study was a descriptive research project conducted from March to June 2015 for the purpose of understanding how university students appreciate the meaning of life. The data, gathered from interviews with a number of university students, who are at the last stage of adolescence, were classified into 102 statements and 30 categories through a series of content analyses of certain subjects, such as the definition and importance of the meaning of life, the endeavor to make life meaningful, the moments they feel the meaning of life, and the methods they adopt to feel the meaning of life. We analyzed the ways in which university students appreciate the meaning of life. We hope this study will provide a small guide for them so that the meaning of their lives can be enriched and their feeling of well-being enhanced. In addition, it is necessary to develop appropriate measures for college students to deal with crises in their life and, thus, the results of this study could be used as an important material for the systematic development of support programs for college students. Finally, this study will provide the basis for multifaceted interventions designed to improve the physical and mental health of college students and help them to adapt to college life.

A Study of the Relation between the Professional Self-Concept and the Practice Performance as Dental Hygienist (치과위생사의 전문직 자아개념과 업무수행과의 관계연구)

  • Kim, Kyung-Seon;Yu, Mi-Sun
    • Journal of dental hygiene science
    • /
    • v.4 no.3
    • /
    • pp.111-115
    • /
    • 2004
  • This study was aimed to establish the self-concept as the dental profession and dedicate to the development of dental hygienist role by understanding the relation between the self-concept of dental hygienist and practice performance as dental hygienist. Following the thorough investigation of this correlation, the importance of self-concept as the dental profession was confirmed, and the understanding about the practice performance as dental hygienist was renewed. Dental hygienist working in dental clinic located in Jeonju city, Jeollabuk-Do were selected as the subjects of this study, and the materials were collected from Mar. 11 to Mar. 25, 2002 for 15 days. SPSS was used for analysis of data to deal with ANOVA and verification of Pearson correlation. The results of this research can be summarized as follows; 1. In comparison of the degree of professional self-concept according to the general characteristics of the subjects, there were significant differences in religion(p<.05) and educational background(p<.01). 2. In comparison of the degree of practice performance according to the general characteristics of the subjects, the results showed the significant difference in religion(p<.05). 3. There were highly significant correlation between the professional self-concept and practice performance as dental hygienist(F=.663, p<.001).

  • PDF

Comparison Between Ultrasonic and X-ray Methods for Imaging the Children′s Growth Plate (어린이 성장판 영상화를 위한 초음파와 X-선 방식의 비교 평가)

  • Kim Sang Hoo;Kim Hyung Jun;Han Eun Ok;Han Seung Moo
    • Journal of Biomedical Engineering Research
    • /
    • v.25 no.6
    • /
    • pp.551-556
    • /
    • 2004
  • The purpose of this study was to suggest a systematic and scientific method for measurement of children's growth development, in which the accuracy of existing diagnosis method has not been concretely examined yet. The most popular method for diagnosis of children's growth is to analyze the opening degree of growth plate in each joint by X-ray image. However, X-ray method has some disadvantages; it is impossible to measure the diagnosis of growth periodically and repeatedly due to the radiation problem. Hence, this study introduced a profile analysis and the algorithm of analyzing the image of growth plate with the BUA(Broadband Ultrasound Attenuation) of calcaneus, to verify the possibility of alternative ultrasonic method harmless to human body. We obtained the images of growth plate in proximal tibiae, phalanges, and calcanei of 269 children (7∼16 years old) with X-ray. And the image of growth plate in calcanei was also obtained front those children with ultrasound. The results showed that the time of the opening degree of growth plate in each joint was almost consistent between X-ray and ultrasonic images. Also, the images of growth plate measured by X-ray and ultrasound showed the high correlation. Therefore, it is expected that the algorithm of ultrasonic profile analysis introduced in this study can replace the existing X-ray method to measure the growth plate correctly.

A Preliminary Study on a Performance-Based Cognitive Function Test : With the Normal Elderly (수행기반 인지기능평가를 위한 예비연구 : 정상 노인을 대상으로)

  • Kwak, Ho-Soung;Park, Ji-Hyuk
    • Therapeutic Science for Rehabilitation
    • /
    • v.8 no.3
    • /
    • pp.43-55
    • /
    • 2019
  • Objective: The purpose of this study is to conduct a preliminary research for the development of a Performance-Based Cognitive Function Test (PCFT) to screen the elderly for cognitive function impairment, and examine the reliability and validity of the test. Methods: A draft version of the Performance-Based Cognitive Function Test (PCFT) was developed and utilized in nine healthy elderly individuals. In order to verify its reliability, we analyzed the internal consistency of the PCFT. In order to verify the concurrent validity of the PCFT, this study analyzed the correlation between motor-cognitive dual task assessments and the Korean version of the Mini-Mental State Examination (MMSE-K). Results: The internal consistency of the PCFT for motor and cognitive tasks was 0.871 and 0.959 (Cronbach's ${\alpha}$), respectively. Concurrent validity of the PCFT, which was performed through motor-cognitive dual task assessments, ranged from 0.755 to 0.964 (Spearman's rho statistic, p < 0.05). In addition, correlation between the cognitive assessment tool and the MMSE-K ranged from 0.849 to 0.943 (p < 0.01). Conclusion: This study verified, and established the reliability and validity of the PCFT. Further studies are required to examine other psychometric properties in a modified PCFT, for screening cognitive function impairments in the elderly.

Study on the Evolution pattern of Tea Industry Service Mode: Focusing on the Needs of Each Generation in GuangXi, China (차 산업 서비스 모델의 변천 패턴에 대한 연구 - 중국 광시 지역 세대별 니즈를 중심으로)

  • Ping, Li;Jang, Wansok;Pan, Yonghwan
    • Journal of the Korea Convergence Society
    • /
    • v.12 no.6
    • /
    • pp.65-74
    • /
    • 2021
  • Since 2020, the GuangXi government of China has focused on the deep integration of tea industry with leisure and cultural tourism, popular science education, health care and elderly care industries. Among the output value targets of the tertiary industry, the GuangXi government plans to achieve 25 billion yuan, and the tea industry is developing rapidly. Through questionnaire survey, field research and interview, this paper studies the differences of demand behavior and selection attributes of tea products among consumers in different years, and finally studies the evolution pattern of service mode of tea industry in GuangXi. The results show that there are obvious differences in life and work style, shopping habits, service design, user experience, social needs and personality needs of each generation consumers in different years. Based on the analysis of demand and behavior habits of tea products, the evolution pattern of service mode of tea industry in GuangXi is studied. Based on the above results, according to the differences of consumers' choice of tea products in different years, the service mode of tea industry in GuangXi is improved The development of tea industry in service design, user experience level is worthy of in-depth attention.

Effects of dietary Gelidium elegans extract on fat metabolism in preadipocyte cell and mice fed a high-fat diet (개별인정원료 우뭇가사리추출물의 체지방 감소에 관한 기능성 고찰)

  • Lee, Boo-Yong;Chung, Hee-Chul
    • Food Science and Industry
    • /
    • v.53 no.4
    • /
    • pp.390-396
    • /
    • 2020
  • We investigated the anti-obesity effect of Gelidium elegans extract (GE) on 3T3-L1 preadipocytes and a high-fat-diet (HFD)-induced mouse model. The results of the present study demonstrated that GE prevents weight gain induced by a high-fat diet (HFD) by modulating the adenosine monophosphate-activated protein kinase (AMPK)-PR domain-containing 16 (PRDM16)-uncoupling protein-1 (UCP-1) pathway in a mice model. Moreover, in vitro results show that GE suppressed adipocyte differentiation by modulating adipogenic regulators, stimulated lipolysis by activating ATGL, and inhibited adipogenesis by downregulating various enzymes associated with triglyceride synthesis. GE was also found to upregulate AMPK phosphorylation as well as the expression of UCP1 and PRDM16 proteins, leading to measurable changes in the beige-like phenotype differentiation of 3T3-L1 cells. Taken together, these findings suggest the role of GE as a functional food ingredient extracted from Gelidium elegans to increase energy expenditure and anti-obesity efficacy.