• Title/Summary/Keyword: Healing System

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Polycarprolactone Ultrafine Fiber Membrane Fabricated Using a Charge-reduced Electrohydrodynamic Process

  • Kim, Geun-Hyung;Yoon, Hyeon;Lee, Haeng-Nam;Park, Gil-Moon;Koh, Young-Ho
    • Macromolecular Research
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    • v.17 no.7
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    • pp.533-537
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    • 2009
  • This paper introduces a modified electro spinning system for biomedical wound-healing applications. The conventional electrospinning process requires a grounded electrode on which highly charged electro spun ultrafine fibers are deposited. Biomedical wound-healing membranes, however, require a very low charge and a low level of remnant solvent on the electrospun membrane, which the conventional process cannot provide. An electrohydrodynamic process complemented with field-controllable electrodes (an auxiliary electrode and guiding electrodes) and an air blowing system was used to produce a membrane, with a considerably reduced charge and low remnant solvent concentration compared to one fabricated using the conventional method. The membrane had a small average pore size (102 nm) and high porosity (85.1%) for prevention of bacterial contamination. In vivo tests on rats showed that these directly electro spun fibrous membranes produced using the modified electro spinning process supported the good healing of skin bums.

Fixed Indoor-BS Selection Based Self-Healing in Indoor Wireless Communication System (인도어 무선통신시스템에서 고정적 인도어기지국 선택을 통한 자가치유 알고리즘)

  • Lee, Howon;Lee, Kisong
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.18 no.7
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    • pp.1540-1546
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    • 2014
  • In order to resolve coverage hole problems caused by indoor-BS (IBS) faults, we propose a new frame structure and practical algorithm based on optimization technique. Our main contributions can be described as follows: 1) a frame structure with healing channels for solving abnormal IBS faults; and 2) an efficient heuristic resource allocation algorithm with fixed IBS selection to reduce the complexity for the optimization problem. Through intensive simulations, we evaluate the performance excellency of our proposed algorithm with respect to average cell capacity and user fairness compared with conventional algorithms.

Crack-Healing Behavior of $Al_2O_3$ Ceramics for Textile Machinery (섬유기기용 $Al_2O_3$계 세라믹스의 균열치유거동)

  • An, B.G.;Kim, M.K.;Ahn, S.H.;Kim, J.W.;Park, I.D.;Nam, K.W.
    • Journal of Power System Engineering
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    • v.10 no.1
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    • pp.60-64
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    • 2006
  • Alumina ceramic for textile machinery was sintered and subjected to three-point bending. A semicircular surface crack was made on each sample. Crack-healing behavior was systematically studied, as a function of crack-healing temperature and crack size. The bending strength and fracture toughness of the crack-healed sample from $1200^{\circ}C\;to\;1400^{\circ}C$ were investigated. A statistical approach based on Weibull distribution was applied to the test data to evaluate the dispersion in the fracture toughness. Alumina ceramic for textile machinery have the ability to heal after cracking, from over $1300^{\circ}C$. The material can completely heal a $65{\mu}m$ diameter semielliptical crack. The fracture toughness could be explained by 2-parameter Weibull distribution.

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Implementing a 1-Night, 2-Day Mental Health Healing Center Program for Dementia Patients and Their Caregivers

  • Seojae Jeon;Do-Eun Lee;Namju Lee;Hyung Won Kang
    • Journal of Oriental Neuropsychiatry
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    • v.35 no.1
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    • pp.27-36
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    • 2024
  • Objectives: This study aimed to assess the effects of a 1-night, 2-day mental health healing center program on the physical stress, autonomic nervous system health, brain activity levels, brain stress, concentration levels, and Patient Health Questionnaire-9 (PHQ-9) scores of dementia patients and their caregivers. Methods: Forty-eight dementia patients (average age 80 years, 14 males and 34 females) and 48 caregivers (average age 65.23 years, 14 males and 34 females) participated in the program. Pre- and post-assessments were conducted to measure the variables. Results: Dementia patients experienced reduced physical stress, increased brain activity levels, decreased brain stress, improved concentration levels, and a significant decrease in PHQ-9 scores (p<0.05). However, there was a tendency for a decline in autonomic nervous system health among dementia patients. A significant decrease in physical stress was seen in caregivers, but no other significant differences were observed. Conclusions: While the 1-night, 2-day mental health healing center program did not produce significant changes in the caregivers of dementia patients, it exhibited overall positive effects in dementia patients. Consequently, mental healing programs should be utilized effectively for dementia patients. Furthermore, investigating the significance of ongoing programs for the mental well-being of dementia caregivers is imperative, mirroring the attention given to dementia patient care.

The comparison of hospital certification between G-SEED and foreign certification criteria (병원시설의 녹색건축 인증기준 국내외 비교연구)

  • Wang, Jeong Joon;Kim, Jung Hyun;Kim, Byung Seon
    • KIEAE Journal
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    • v.14 no.4
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    • pp.81-89
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    • 2014
  • This research introduces necessity to derive new certification criteria for the hospital considering healing environmental factors in G-SEED. The method of research is reference study to discuss concept of healing environment factors and case study to find ways for problem and improvement by comparison of G-SEED with foreign certification system. And the research conclusion is such as follows. First, it is necessary to develop certification criteria of the hospital for G-SEED which is lack of healing environmental assessment factors unlike foreign certification system. Second, The hospitals are certified by criteria of The Other Buildings in G-SEED which dose not take into account the characteristics of the hospital. Especially hospital waste and use of enormous water are the important factors required, which is already evaluated in foreign certification criteria.

A Path Control Switch in SDH-based Transmission System (SDH 전송시스템에서의 경로제어스위치)

  • Lee, Sang-Hoon;Koh, Jung-Hyuk;Sung, Yung-Kwon
    • Proceedings of the KIEE Conference
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    • 1998.11b
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    • pp.594-596
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    • 1998
  • In this paper, a path control switch has been developed for self-healing operation in SDH-based transmission system. The proposed switch is suitable for self-healing operations in both an Unidirectional Path Switched Ring and a 2-fiber Bidirectional Line Switched Ring. The path control switch is implemented with $0.8{\mu}m$ CMOS LSI chip. The self-healing operation of the switch is effectively done by the configuration information stored in the registers of the switch. The switch has an AU-3(51.84Mb/s) TSI(Time Slot Interchange) and has 1.25Gb/s throughput. But the higher throughput can be realized by combining two identical switches or more with the parallel architecture.

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Topical Gel Formulations of Epidermal Growth Factor and Their Wound Healing Effects (상피세포 성장인자를 함유한 외용 겔 제제의 특성 및 창상 치유 효과)

  • Lee, Jeong-U;Kim, Hui-Jun;Jo, Seong-Wan;Park, Jun-Sang;Choe, Yeong-Uk
    • YAKHAK HOEJI
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    • v.40 no.4
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    • pp.411-417
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    • 1996
  • Epidermal growth factor(EGF), a potential healing agent for wounds and burns, has been formulated to topical gels with the hydrophilic polymers, Carbopol 934P. Physicochemical c haracteristics of the aqueous gels were evaluated by rheological properties and pH changes on storage. The gels were relatively stable at $4^{\circ}C$ and room temperature showing no changes in pH for two weeks, and revealed the rheogram of shear thinning plastic flow with the yield values in the range of 40 to 70dyne/$cm^2$. In vivo healing effects of different gel formulations have been compared with water-soluble and oleaginous ointments in full-thickness wound mouse model. The gel systems resulted in better wound healing effects than the other ointments. Furthermore, liposomal Carbopol gel has been developed by the addition of EGF-containing liposomal suspension into the Carbopol gel. The enhanced wound healing effects have been observed in the liposomal gel system, compared to the other gels and conventional ointments.

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A study on wound healing activity of Bacopa monnieri Linn. aerial parts

  • Ghosh, Tirtha;Maity, Tapan Kumar;Dash, Deepak Kumar;Boss, Anindya
    • Advances in Traditional Medicine
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    • v.7 no.2
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    • pp.150-156
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    • 2007
  • Bacopa monnieri is being used in the traditional system of medicine for a variety of ailments. In the present study, the ethanolic extract of Bacopa monnieri aerial parts has been studied for its wound healing activity using various models in rats. Significant increase in wound contraction and skin breaking strength were observed in the excision and incision wound models respectively. There was also significant increase in hydroxyproline content, DNA content, superoxide dismutase activity, catalase activity, glutathione level and decrease in the level of thiobarbituric acid reactive substances in the $12^{th}$ day post wounding tissue of experimental rats in the ethanol extract treated groups with respect to the control group. The effect of the extract was found to be comparable with the standard drug nitrofurazone. From the results it may be concluded that the plant Bacopa monnieri is endowed with significant wound healing activity, thereby justifying its use in the traditional medicine. Saponins may be responsible for the observed wound healing activity.

The Effect of Caffeic Acid on Wound Healing in Skin-incised Mice

  • Song, Ho-Sun;Park, Tae-Wook;Sohn, Uy-Dong;Shin, Yong-Kyoo;Choi, Byung-Chul;Kim, Chang-Jong;Sim, Sang-Soo
    • The Korean Journal of Physiology and Pharmacology
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    • v.12 no.6
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    • pp.343-347
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    • 2008
  • This study was carried out to investigate the wound healing effect of caffeic acid in skin-incised mice. Caffeic acid showed significant effects on anti-inflammatory activity and wound healing, such as myeloperoxidase activity, lipid peroxidation, phospholipase $A_2$ activity and collagen-like polymer synthesis, in incised-wound tissue. On the other hand, it significantly stimulated collagen-like polymer synthesis in NIH 3T3 fibroblast cells, while inhibited both silica-induced reactive oxygen species generation and melittin-induced arachidonic acid release and $PGE_2$ production in Raw 264.7 cells, and histamine release in RBL 2H3 cells stimulated by melittin or arachidonic acid. Therefore, caffeic acid appears to have a potent antioxidant and anti-inflammatory effect in cell culture system, which may be related to wound healing in skin-incised mice.

Prospective randomized clinical trial of hydrophilic tapered implant placement at maxillary posterior area: 6 weeks and 12 weeks loading

  • Kim, Seong-Beom;Yun, Pil-Young;Kim, Sang-Yun;Yi, Yang-Jin;Kim, Ji-Yun;Kim, Young-Kyun
    • The Journal of Advanced Prosthodontics
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    • v.8 no.5
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    • pp.396-403
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    • 2016
  • PURPOSE. Early loading of implant can be determined by excellent primary stability and characteristic of implant surface. The implant system with recently improved surface can have load application 4-6 weeks after installing in maxilla and mandible. This study evaluated the effect of healing period to the stability of hydrophilic tapered-type implant at maxillary posterior area. MATERIALS AND METHODS. This study included 30 patients treated by hydrophilic tapered-type implants (total 41 implants at maxilla) and classified by two groups depending on healing period. Group 1 (11 patients, 15 implants) was a control group and the healing period was 12 weeks, and Group 2 (19 patients, 26 implants) was test group and the healing period was 6 weeks. Immediately after implant placement, at the first impression taking, implant stability was measured using Osstell Mentor. The patients also took periapical radiographs after restoration delivery, 12 months after restoration and final followup period. The marginal bone loss around the implants was measured using the periapical radiographs. RESULTS. All implants were survived and success rate was 97.56%. The marginal bone loss was less than 1mm after 1 year postoperatively except the one implant. The stabilities of the implants were not correlated with age, healing period until loading, insertion torque (IT), the diameter of fixture and the location of implant. Only the quality of bone in group 2 (6 week) was correlated with the stability of implant. CONCLUSION. Healing period of 6 weeks can make the similar clinical prognosis of implants to that of healing period of 12 weeks if bone quality is carefully considered in case of early loading.