• Journal of Society of Preventive Korean Medicine
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• v.3 no.2
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• pp.91-100
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• 1999

Today, toxicology is used for many purpose, in many fields. Classification of special toxic effect is related next 4 important principles. 1. The chemical substance must move to target organ or tissue that can induce Biological effect. For this movement, we have to understand the physical-chemical characteristic of substance, and the rout of absorption, metabolism, diffusion and excretion of toxic substance. 2. Every biological effect that induced by chemical substance is not harmful. For example, some specific chemical substance is not harmful in liver enzyme system. 3. The strength of biological effect induced by chemical substance is deep related with dose. Nearly all substance is not effective below the specific dose, and it may toxic to death over the specific dose. It is the 'Dose - response relationship' But carcinogen may toxic whether it is law dose or not. 4. The information that was obtained by experimental animal test, could have to adapt in human biology. Because biological effect of chemical substance could be different in every biological species. In past, drugs was obtained by animal or plants. But in the future, it could be obtained by biochemistry, and genome project. Therefore, in Oriental medicine, research and approach is needed at this time, and have to develop new method of experience in toxic method.

• KIEAE Journal
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• v.7 no.4
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• pp.135-140
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• 2007

In this study we settled the trouble of the MgO board of existence by this research. We changed the wooden one of the main ingredient of a board to a perlite and a mineral particle in the aluminum hydroxide group and proceeded with a study to physical character and fire resistance efficiency improvement. The result yellowing phenomenon could be improved and it was possible to reduce size decrease of pin hole and the frequency of occurrence. We found out that the in case of absorbed amount added 5~8% corresponding to the weight decreases the acrylic group emulsion suddenly. So this product is improved with the bending strength and water-resistance. After behavior stop time measurement of a mouse for experiments was measured at the time of a gas harmful effect test, an improved MgO board appeared more highly for an average of 138 seconds compared with a board of existence.

• Transactions of the Korean Society of Machine Tool Engineers
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• v.17 no.1
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• pp.43-49
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• 2008

This study is about an influence of harmful factors of welding fumes such as Fe, Mn, Cu, Zn to workers who inhales them in welding sites. The influence can be measured with the density of heavy metals in blood after welding. The main factors of the measurement are TWA, a density of welding fume, and a level of heavy metals. The results indicate that there is a positive effect of moving fans as a way of improving the condition in welding workplaces. While welding was done, TWA exceeded the level of Fe 40% and Zn 10% and the level of heavy metals in blood was below the standard for the workers who were under the experiment. Also when the wind was applied on the front side by a fan, the welding fume significantly reduced. It can be concluded that wearing protection gears with safety devices is one of important factors.

• Journal of The Korean Society of Grassland and Forage Science
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• v.15 no.3
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• pp.186-191
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• 1995

This study was conducted to evaluate the effect of herbicides on weed control, growth characteristics and yield in rapes, after direct seeding it to the field. All herbicides treated had no effect on the emergence period, bolting rate of rapes. The major weeds were Cerastium holosteoides var. hallaisanense, Stellaria media Villars, Larnium ampleicaule L., Lobelia chinensis Lour., Geranium wilfordii Maxim. and Capsellu bursa-pastoris (L.) Medicus. Rapes yield were increased somewhat more with alachlor-G, herbicide than the other hehicides and by hand weeding. Alachlor-G and alachlor-Ec were had no i j u r y but butachlor- G and simajin-Wp were slightly harmful for the rapes with recommended concentration. On the other hand all hehicides were harmful in the double dosage level.

• Korean Journal of Food Science and Technology
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• v.33 no.1
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• pp.142-145
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• 2001

The objective of this study was to evaluate the in vivo effect of Lentinus edodes on the harmful enzymes of mouse intestinal bacteria. When mouse intestinal microflora were cultured in the anaerobic media containing Lentinus edodes water extract or trehalose (LD) isolated From its extract, final pH of the cultured media was significantly decreased and the activities of harmful enzymes, particulary ${\beta}-glucuronidase$ and tryptophanase, were significantly inhibited. By orally administering Lentinus edodes water extract or LD, mouse fecal ${\beta}-glucuronidase$ and tryptophanase were also signifcantly inhibited.

• Tuberculosis and Respiratory Diseases
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• v.86 no.1
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• pp.23-32
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• 2023

Everyone is aware that air and environmental pollutants are harmful to health. Among them, indoor air quality directly affects physical health, such as respiratory rather than outdoor air. However, studies that have examined the correlation between environmental and health information have been conducted with public data targeting large cohorts, and studies with real-time data analysis are insufficient. Therefore, this research explores the research with an indoor air quality monitoring (AQM) system based on developing environmental detection sensors and the internet of things to collect, monitor, and analyze environmental and health data from various data sources in real-time. It explores the usage of wearable devices for health monitoring systems. In addition, the availability of big data and artificial intelligence analysis and prediction has increased, investigating algorithmic studies for accurate prediction of hazardous environments and health impacts. Regarding health effects, techniques to prevent respiratory and related diseases were reviewed.

• Environmental Analysis Health and Toxicology
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• v.21 no.2 s.53
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• pp.173-184
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• 2006

From the harmfulness expectation test conducted through a toxicity anticipation program, methylcyclohexane turned out to be harmful and simulative, but no carcinogenicity was anticipated. In a four-hour acute inhalation toxicity test, the result showed that lethal concentration ($LC_{50}$) was 3,750 ppm (15,054 mg/L), which was identified as a harmful substance on the basis of the harmful substance classification standard $2 of the Industrial safety and health law. methylcyclohexane fell under the category $4(2,500 substance from the GHS standard acute toxicity harmfulness classification. Also, from subchronic inhalation toxicity test that included 6 hours a day, five days a week, and for 13 weeks, we could observe weight, activity, long term weight, blood and blood biochemical influence from the exposure of test substance. No-observed effect level (NOEL) was determined below $100{\sim}400ppm$ inboth male and female. This material falls under the Category 2 ($50{\sim}250ppm/6hours/90days$) in the GHS (Globally Harmonized System) standard trace long-term whole body toxicity repeated exposure, and can be classified as a harmful substance in accordance with the Industrial Safety and Health Law harmful substance standard $NOEL{\leq}0.5mg/L/6hr/90day$ (rat).

• Proceedings of the IEEK Conference
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• 2002.06b
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• pp.263-266
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• 2002

• Child Health Nursing Research
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• v.10 no.1
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• pp.108-116
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• 2004

Purpose: There has been a number of reports on elution of bisphenol-A, an endocrine disrupting chemical, from milk bottles, all concerning the potential health effect of the substance. In this study, we measured the elution of bisphenol-A from milk bottles during boiling-water sterilization, to suggest a safe sterilization method. Method: Through the survey of 200 mothers, 78.5％ of them expressed their concern on the possible harmful effect of bisphenol-A, which might be eluted from the bottles. And it was found that most mothers use boiling-water to sterilize bottles; duration of boiling bottles could be divided into three groups of 3, 5, and 10 minutes. We measured the elution of bisphenol- A from three different brands of bottles, subject to various mode of sterilization found in the survey. Result: In all the measurements, the concentration of the eluted bisphenol-A was in the range of 0.3 - 0.7 ppb, far below 2.5ppm, the level set up by Korea Food ％amp; Drug Administration(KFDA) for a potential harmful effect. Conclusion: Although trace amount of bisphenol -A can be eluted from polycarbonate milk bottles during sterilization, and bottle feeding, the amount is found to be too small to cause any health related impact for infants.

• Journal of the Korean Society of Marine Environment & Safety
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• v.14 no.4
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• pp.289-295
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• 2008

The disposal of constructive waste is emerging as a national and social issue and the recycled powder generated by the production of reproductive aggregate is all being abolished or buried Analysis on the harmful effect of recycled powder indicated that because it contained massive cytotoxicity, it could derive secondary pollution to soil and subterranean water. This study set on an idea that one way to recycle recycled powder was to use it as a compound of concrete. In order to study that prospect, recycled powder, instead of cement, was mixed and a comparative analysis was conducted on the mechanical properties and workability. From experimental results, it was judged that application of recycled powder of cement replacement ratio below 20% was available with chemical admixtures. Also application of recycled powder was available to high strength concrete.