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A Study on the Hazardousness Evaluation and the Inhalation Toxicity of Methylcyclohexane  

Kim Hyeon-Yeong (Center for Occupational Toxicology, Occupational Safety & Health Research Institute, Korea Occupational Safety & Health Agency)
Lee Sung-Bae (Center for Occupational Toxicology, Occupational Safety & Health Research Institute, Korea Occupational Safety & Health Agency)
Kang Min-Gu (Center for Occupational Toxicology, Occupational Safety & Health Research Institute, Korea Occupational Safety & Health Agency)
Song Si-Hwan (Chemon)
Publication Information
Environmental Analysis Health and Toxicology / v.21, no.2, 2006 , pp. 173-184 More about this Journal
Abstract
From the harmfulness expectation test conducted through a toxicity anticipation program, methylcyclohexane turned out to be harmful and simulative, but no carcinogenicity was anticipated. In a four-hour acute inhalation toxicity test, the result showed that lethal concentration ($LC_{50}$) was 3,750 ppm (15,054 mg/L), which was identified as a harmful substance on the basis of the harmful substance classification standard $2 inboth male and female. This material falls under the Category 2 ($50{\sim}250ppm/6hours/90days$) in the GHS (Globally Harmonized System) standard trace long-term whole body toxicity repeated exposure, and can be classified as a harmful substance in accordance with the Industrial Safety and Health Law harmful substance standard $NOEL{\leq}0.5mg/L/6hr/90day$ (rat).
Keywords
methylcyclohexane; inhalation toxicity; NOEL; MSDS;
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