• Journal of the Korean Association of Geographic Information Studies
• /
• v.22 no.4
• /
• pp.215-228
• /
• 2019

HDF5 data format is used to effectively store and distribute large volume of Geostationary Ocean Color Imager(GOCI) satellite data. The Korea Ocean Satellite Center has developed and provided a GOCI Data Processing System(GDPS) for general users who are not familiar with HDF5 format. Nevertheless, it is not easy to merge and process Hierarchical Data Format version5(HDF5) data that requires an understanding of satellite data characteristics, needs to learn how to use GDPS, and stores location and attribute information separately. Therefore, the open source R and rhdf5, data.table, and matrixStats packages were used to develop algorithm that could easily utilize satellite data in HDF5 format without the need for the process of using GDPS.

• Natural Product Sciences
• /
• v.25 no.3
• /
• pp.208-214
• /
• 2019

Trigonella foenum-graceum L. (fenugreek) is a phytoestrogen, a nonsteroidal organic chemical compound from plants which has similar mechanism of action to sex hormone estradiol-$17{\beta}$. This study aims to assess the effectivity of fenugreek seeds extract on collagen type I alpha 1 (COL1A1) and collagen type III alpha 1 (COL3A1) which are both decreased in aging skin and become worsen after menopause. This in vitro experimental study used old human dermal fibroblast from leftover tissue of blepharoplasty on a postmenopausal woman (old HDF). As a control of the fenugreek's ability to trigger collagen production, we used fibroblast from preputium (young HDF). Subsequent to fibroblast isolation and culture, toxicity test was conducted on both old and young HDF by measuring cell viability on fenugreek extract with the concentration of 5 mg/mL to $1.2{\mu}g/mL$ which will be tested on both HDF to examine COL1A1 and COL3A1 using ELISA, compared to no treatment and 5 nM estradiol. Old HDF showed a 4 times slower proliferation compared to young HDF (p<0.05). Toxicity test revealed fenugreek concentration of $0.5-2{\mu}g/mL$ was non-toxic to both old and young HDF. The most significant fenugreek concentration to increase COL1A1 and COL3A1 secretion was $2{\mu}g/mL$ (p<0.05).

• ETRI Journal
• /
• v.40 no.1
• /
• pp.122-132
• /
• 2018

This paper proposes a hierarchical dual filtering (HDF) algorithm to estimate the spatial region between a Cloud of Things (CoT) gateway and an Internet of Things (IoT) device. The accuracy of the spatial region estimation is important for autonomous CoT clustering. We conduct spatial region estimation using a hidden Markov model (HMM) with a raw Bluetooth received signal strength indicator (RSSI). However, the accuracy of the region estimation using the validation data is only 53.8%. To increase the accuracy of the spatial region estimation, the HDF algorithm removes the high-frequency signals hierarchically, and alters the parameters according to whether the IoT device moves. The accuracy of spatial region estimation using a raw RSSI, Kalman filter, and HDF are compared to evaluate the effectiveness of the HDF algorithm. The success rate and root mean square error (RMSE) of all regions are 0.538, 0.622, and 0.75, and 0.997, 0.812, and 0.5 when raw RSSI, a Kalman filter, and HDF are used, respectively. The HDF algorithm attains the best results in terms of the success rate and RMSE of spatial region estimation using HMM.

• Journal of the Korean Applied Science and Technology
• /
• v.37 no.5
• /
• pp.1180-1189
• /
• 2020

This study attempted to investigate the physiological activities of Passiflora caerulea extract and provide basic data needed to verify its availability as an inner beauty material. To examine its anti-oxidant, anti-inflammatory and anti-aging effects, the followings were measured: total polyphenol contents, total flavonoid contents, DPPH radical scavenging activity, cytotoxicity and NO inhibition effects in RAW 264.7 macrophage cells and HDF cells and MMP-1 inhibitory effects in HDF cells. The results found the followings: First, polyphenol and flavonoid contents were great with 157 mg/g and 173.5 mg/g respectively at 10mg/mL, and DPPH radical scavenging activity was confirmed. In RAW 264.7 macrophage cells and HDF cells, no cytotoxicity was observed for Passiflora caerulea extract. In addition, 69.3% anti-inflammatory effects were found at 100 ㎍/mL through NO inhibition in RAW 264.7 macrophage cells. In addition, a significant inhibition of MMP-1 expression in HDF cell was confirmed. The above results confirmed the anti-oxidant and anti-inflammatory effects of Passiflora caerulea extract, low toxicity on skin cells and its anti-aging effects by inhibiting MMP-1 expression. Therefore, it appears that Passiflora caerulea extract would be available as diverse inner beauty materials.

• Journal of the Korean Applied Science and Technology
• /
• v.35 no.3
• /
• pp.797-806
• /
• 2018

This study attempted to investigate the effects of Paeonia Lactiflora Pallas (P. lactiflora) on the inhibition of oxygen free radical, anti-inflammation and MMP-1 inhibitory activity and examine its possibility as a functional cosmetic material. For test methods, the inhibition of oxygen free radical after measuring reactive oxygen species (ROS) in the cell, cytotoxicity assessment and anti-inflammation were measured, and MMP-1 inhibitory effects in the HDF cell were measured. According to the test, the inhibition of ROS was confirmed in RAW 264.7 and HDF cells. In terms of cytotoxicity assessment, 90% or higher cell viability was detected at $5/10{\mu}g/mL$ Paeonia Lactiflora Pallas extract while it was 80% or higher at other concentration levels in both RAW 264.7 and HDF cells. In addition, NO production was inhibited in the RAW 264.7 cell while MMP-1 was significantly inhibited in the HDF cell. The above results reveal a possibility of Paeonia Lactiflora Pallas extract as a functional cosmetic material after confirming the inhibition of ROS synthesis in the cell, antioxidant and anti-inflammatory effects by inhibiting NO synthesis, low toxicity on skin cells and anti-aging effect through MMP-1 inhibition.

• Journal of the Korean Wood Science and Technology
• /
• v.40 no.2
• /
• pp.101-109
• /
• 2012

Wood composites are a hygroscopic material and have ability to exchange its moisture content with air. This study investigated the formaldehyde emission and moisture content change of four wood composites (particleboard (PB), medium density fiberboard (MDF), high density fiberboard (HDF), laminated HDF (L-HDF)) as a function of bake-out temperature and time. The composites were baked out for 1, 3, 5, 7, 10, 14, 21, and 28 days at temperatures of $20{\pm}2$, $35{\pm}2$, and $50{\pm}2^{\circ}C$ in a dry oven. The moisture content change was used to determine the emission bake-out of the composites. Best bake-out time results were obtained with after 7 days all composites. Formaldehyde emission values of composites decreased with decreasing moisture content for both temperatures. The formaldehyde emission results of bake-out temperature 35 and $50^{\circ}C$ showed a similar tendency.

• Korean Journal of Ecology and Environment
• /
• v.45 no.1
• /
• pp.129-138
• /
• 2012

We investigated an ecological impact of drought simulated by discharge depletion on the water quality and benthic diatom community in the indoor experimental channel. As artificial substrates slide-glass was installed in acrylic channel for 16 days. Channels were supplied continuously with eutrophic lake water with a discharge rate of 6 L $min^{-1}$ in duplication during the colonized period. And then during the discharge depletion period, three discharge rates were provided: NDF (No depletion of flow rate (Control): 6 L $min^{-1}$), LDF (Low depletion of flow rate: 3 L $min^{-1}$) and HDF (High depletion of flow rate: 1 L $min^{-1}$). Environmental factors in the water, such as suspended solid, Chl-$a$ and nutrients concentration, were measured with periphytic algae including AFDM (ash free dry matter), Chl-$a$ concentration and cell density at 1-day intervals. Light intensity increased significantly with discharge depletion (F=229.5, p= 0.000). $NH_4$-N concentration was highest at HDF. Suspended solid in outflowing water decreased at HDF (88%), LDF (97%) and NDF (99%), compared to inflowing water (100 %). Chl-$a$ in substrates increased more than two times at LDF and HDF than NDF (F= 8.399, p=0.001). Also AFDM and benthic diatom density increased significantly at LDF and HDF than NDF (F=9.390, p=0.001; F=6.088, p=0.007). In all experimental groups, $Aulacoseira$ $ambigua$, $Achnanthes$ $minutissima$ and $Aulacoseira$ $granulata$ were dominant species accounting for greater than 10% of benthic diatom density. The most dominant species, $A.$ $ambigua$ was highest at LDF, followed by HDF and NDF (F=8.551, p=0.001). In conclusion, the effect of drought simulated by discharge depletion in an artificial stream ecosystem caused significant changes on water quality and benthic diatom biomass. This result provides a useful data to understand the effect of draught on stream ecosystem in situ.

• Journal of Life Science
• /
• v.30 no.8
• /
• pp.680-687
• /
• 2020

Several studies have proved Hovenia dulcis extracts to be an effective antidote for alcoholism, and they are frequently used in the clinical treatment of alcoholic liver disease. The purpose of this study was to investigate the anti-oxidant and anti-senescent activities of 80% methanol fractions of H. dulcis Thunberg in human dermal fibroblast (HDF) cells. The ethanol ethyl acetate fraction showed the highest inhibition of 2,2-diphenyl-1-picryhydrazyl radical scavenging (RC₅₀=3.6±0.8 ㎍/ml) as well as the highest total phenol content (417.2antiholic liver disease. Extracts from e & Tech., Sungkyunkwan University, progressed in the HDF cells, SM22 expression (p<0.001) and β-galactosidase staining intensity increased (p<0.001). An increase in SM22 expression is associated with slower aging which suggests that its expression is high in early aging. HDF treatment using the ethyl acetate fraction significantly increased production of EGF (p<0.01) and PDGF-BB (p<0.01) while SHH expression was reduced (p<0.05). These results suggest that an 80% ethyl acetate fraction of H. dulcis can suppress early aging and demonstrate the potential application of the fraction as a natural anti-senescence agent.

• Spatial Information Research
• /
• v.9 no.1
• /
• pp.31-50
• /
• 2001

This study has analyzed GeoTIFF, SDTS, HDF, and BIIF as the representative formats of spatial imagery information with two parts. First is to compare 4 formats with each other based on 4 comparison criteria (extensibility, interchangeability, current widespread use, long-term stability) by analyzing specification of each format. Second is to estimate current use and interchangeability of 4 formats between 5 commercial softwares used commonly. The result shows that GeoTIFF is currently better than three other formats. However, the more various spatial imagery information are and the larger capacity they have, the more formats are developed and updated, which means that only one format should not be considered as a standard format continuously. It is better to provide a standard format proper to the time through continuous research and sustainable policy support should be followed.

• Journal of the Society of Cosmetic Scientists of Korea
• /
• v.31 no.2 s.51
• /
• pp.161-167
• /
• 2005

We investigated the effect on inhibition of matrix metalloproteinase (MMP) in human dermal fibroblast (HDF) by production of exopolysaccharide (GF-glucan) from mycelial culture of Grifola frondosa HB0071. The photoprotective potential of GF-glucan was tested in HDF exposed to ultraviolet-A (UVA) light. It was revealed that GF-glucan had an inhibitory effect on MMP-1 expression in UVA-irradiated HDF without any significant cytotoxicity. The treatment of UVA-irradiated HDF with GF-glucan resulted in a dose-dependent degrease in the expression level of MMP-1 protein and mRNA (by maximum $54.4\%$ at an $0.5\%$ GF-glucan). These results suggest that GF-glucan obtained from mycelial culture of G. frondosa HB0071 may contribute to inhibitory action in photoaging by reducing the MMP-1 related matrix degradation system.