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http://dx.doi.org/10.12925/jkocs.2020.37.5.1180

Availability of Passiflora Caerulea Extract as Inner Beauty Material  

Lee, Jae-Nam (Department of Cosmetology, Graduate School of Engineering, Konkuk University)
Kem, Young-Sam (Dept. of Image Industry, Graduate School of Engineering, Konkuk University)
Publication Information
Journal of the Korean Applied Science and Technology / v.37, no.5, 2020 , pp. 1180-1189 More about this Journal
Abstract
This study attempted to investigate the physiological activities of Passiflora caerulea extract and provide basic data needed to verify its availability as an inner beauty material. To examine its anti-oxidant, anti-inflammatory and anti-aging effects, the followings were measured: total polyphenol contents, total flavonoid contents, DPPH radical scavenging activity, cytotoxicity and NO inhibition effects in RAW 264.7 macrophage cells and HDF cells and MMP-1 inhibitory effects in HDF cells. The results found the followings: First, polyphenol and flavonoid contents were great with 157 mg/g and 173.5 mg/g respectively at 10mg/mL, and DPPH radical scavenging activity was confirmed. In RAW 264.7 macrophage cells and HDF cells, no cytotoxicity was observed for Passiflora caerulea extract. In addition, 69.3% anti-inflammatory effects were found at 100 ㎍/mL through NO inhibition in RAW 264.7 macrophage cells. In addition, a significant inhibition of MMP-1 expression in HDF cell was confirmed. The above results confirmed the anti-oxidant and anti-inflammatory effects of Passiflora caerulea extract, low toxicity on skin cells and its anti-aging effects by inhibiting MMP-1 expression. Therefore, it appears that Passiflora caerulea extract would be available as diverse inner beauty materials.
Keywords
Passiflora caerulea extract; anti-oxidant; anti-inflammatory; Inner Beauty;
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