• Title/Summary/Keyword: HBM

Search Result 121, Processing Time 0.035 seconds

The Effect of HBM(Healthy Body Maker) on the Body Weight Loss and Serum Cholesterol Level in Rats (한방 다이어트 식품 HBM(Healthy Body Maker)의 체중감소 및 혈청 콜레스테롤 저하 효과)

  • 박재상;김애정;김선여
    • Journal of the East Asian Society of Dietary Life
    • /
    • v.11 no.4
    • /
    • pp.268-273
    • /
    • 2001
  • This study was performed to investigate the effects of HBM(Healthy Body Maker) on the weight loss and serum cholesterol level of rats. Twenty male Sprague-Dawley rats weighing 200$\pm$5g were grouped into 2. Rats were raised for 6 weeks with diet containing 0% and 5% of HBM. 1. There were no clinical signs for all the experimental period(6 weeks) in 0% and 5% groups. 2. At 3 and 6 weeks. body weight of 5% HBM group was significantly lower than that of control group. respectively(p<0.05, p<0.01). 3. At 4 weeks. the level of MCHC of 5% HBM group was significantly higher than that of control group(p<0.01) And at 6 weeks the level of RBC and Hct of 5% HBM group were significantly higher than those of control group(p<0.05) 4. At 6 weeks. the level of serum cholesterol of 5% HBM group was significantly lower than that of control group. 5. Absolute liver weight of 5% HBM group was significantly lower than that of control group(p<0.05). 6. Minor subaceous sickness of liver cell in the control group appeared but no symptom of liver cell in 5% HBM group. It is concluded that HBM was a safe and effective diet food which aided in inducing weight loss in rat without any observed harmful clinical side effects.

  • PDF

Knowledge Modeling and Database Construction for Human Biomonitoring Data (인체 바이오모니터링 지식 모델링 및 데이터베이스 구축)

  • Lee, Jangwoo;Yang, Sehee;Lee, Hunjoo
    • Journal of Food Hygiene and Safety
    • /
    • v.35 no.6
    • /
    • pp.607-617
    • /
    • 2020
  • Human bio-monitoring (HBM) data is a very important resource for tracking total exposure and concentrations of a parent chemical or its metabolites in human biomarkers. However, until now, it was difficult to execute the integration of different types of HBM data due to incompatibility problems caused by gaps in study design, chemical description and coding system between different sources in Korea. In this study, we presented a standardized code system and HBM knowledge model (KM) based on relational database modeling methodology. For this purpose, we used 11 raw datasets collected from the Ministry of Food and Drug Safety (MFDS) between 2006 and 2018. We then constructed the HBM database (DB) using a total of 205,491 concentration-related data points for 18,870 participants and 86 chemicals. In addition, we developed a summary report-type statistical analysis program to verify the inputted HBM datasets. This study will contribute to promoting the sustainable creation and versatile utilization of big-data for HBM results at the MFDS.

Components of human breast milk: from macronutrient to microbiome and microRNA

  • Kim, Su Yeong;Yi, Dae Yong
    • Clinical and Experimental Pediatrics
    • /
    • v.63 no.8
    • /
    • pp.301-309
    • /
    • 2020
  • Human breast milk (HBM) is essential for the infant's growth and development right after birth and is an irreplaceable source of nutrition for early human survival. Various infant formulas have many similarities to HBM in many components, but there is no perfect substitute for HBM. Recently, various breast milk components and their roles have been studied according to the development of various analysis techniques. As is already well known, HBM contains about 87%-88% water, and 124-g/L solid components as macronutrients, including about 7% (60-70 g/L) carbohydrates, 1% (8-10 g/L) protein, and 3.8% (35-40 g/L) fat. The composition may vary depending on the environmental factors, including maternal diet. Colostrum is low in fat but high in protein and relatively rich in immuneprotective components. Although HBM contains enough vitamins to ensure normal growth of the infant, vitamins D and K may be insufficient, and the infant may require their supplementation. Growth factors in HBM also serve as various bioactive proteins and peptides on the intestinal tract, vasculature, nervous system, and endocrine system. In the past, HBM of a healthy mother was thought to be sterile. However, several subsequent studies have confirmed the presence of rich and diverse microbial communities in HBM. Some studies suggested that the genera Staphylococcus and Streptococcus may be universally predominant in HBM, but the origin of microbiota still remains controversial. Lastly, milk is the one of most abundant body fluid of microRNAs, which are known to play a role in various functions, such as immunoprotection and developmental programming, through delivering from HBM and absorption by intestinal epithelial cells. In conclusion, HBM is the most important source of nutrition for infants and includes microbiomes and miRNAs for growth, development, and immunity.

HBM ESD Tester for On-wafer Test using Flyback Method (Flyback 방식을 이용한 on-wafer용 HBM ESD 테스터 구현)

  • 박창근;염기수
    • Journal of the Korea Institute of Information and Communication Engineering
    • /
    • v.6 no.7
    • /
    • pp.1079-1083
    • /
    • 2002
  • We made ESD tester to measure ESD threshold voltage of semiconductor devices. The HBM ESD test is the most popular method to measure the ESD threshold voltage of MMSIC. We use flyback method which is one of the DC-DC converter to get high ESD voltage. With flvback method, we can isolate the 1ow voltage part from the high voltage part of HBM ESD tester. We use an air gap of the relay which is used for switch to satisfy the rise time of ESD standard(MIL-STD). As a result, with the flyback method and the air gap of relay, we can make ESD tester whose parasitic components are minimized.

HBM ESD Tester for On-wafer Test using Flyback Method (Flyback방식을 이용한 on-wafer용 HBM ESD 테스터 구현)

  • 박창근;염기수
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
    • /
    • 2002.11a
    • /
    • pp.469-472
    • /
    • 2002
  • We made ESD tester to measure ESD threshold voltage of semiconductor devices. The HBM ESD test is the most popular method to measure the ESD threshold voltage of MMIC. We use flyback method which is one of the DC-DC converter to get high ESD voltage. With flyback method, we can isolate the low voltage part from the high voltage part of HBM ESD tester. We use an air gap of the relay which is used for switch to satisfy the rise time of ESD standard(MIL-STll-883D). As a result, with the flyback method and the air gap of relay, we can make ESD tester whose parasitic components are minimized.

  • PDF

Mixed-Mode Transient Analysis of HBM ESD Phenomena (HBM ESD 현상의 혼합모드 과도해석)

  • Choe, Jin-Yeong;Song, Gwang-Seop
    • Journal of the Institute of Electronics Engineers of Korea SD
    • /
    • v.38 no.1
    • /
    • pp.1-12
    • /
    • 2001
  • Based on mixed-mode transient analyses utilizing a 2-dimensional device simulator, we have suggested the methodology to analyze the HBM ESD phenomena in CMOS chips utilizing NMOS transistors for ESD protection, and have analyzes the HBM discharge mechanisms in detail. Also the second breakdown characteristics in the protection device have been successfully simulated based on mixed-mode simulations, to explain the discharge mechanisms leading to device failure. To analyze the effects of the device structure changes on the discharge characteristics, we have compared the results of DC analyses and mixed-mode transient analyses, and have discussed about more robust designs of NMOS transistor structures against HBM ESD based on the analyses.

  • PDF

Electrostatic discharge simulation of tunneling magnetoresistance devices (터널링 자기저항 소자의 정전기 방전 시뮬레이션)

  • Park, S.Y.;Choi, Y.B.;Jo, S.C.
    • Journal of the Korean Magnetics Society
    • /
    • v.12 no.5
    • /
    • pp.168-173
    • /
    • 2002
  • Electrostatic discharge characteristics were studied by connecting human body model (HBM) with tunneling magnetoresistance (TMR) device in this research. TMR samples were converted into electrical equivalent circuit with HBM and it was simulated utilizing PSPICE. Discharge characteristics were observed by changing the component values of the junction model in this equivalent circuit. The results show that resistance and capacitance of the TMR junction were determinative components that dominate the sensitivity of the electrostatic discharge(ESD). Reducing the resistance oi the junction area and lead line is more profitable to increase the recording density rather than increasing the capacitance to improve the endurance for ESD events. Endurance at DC state was performed by checking breakdown and failure voltages for applied DC voltage. HBM voltage that a TMR device could endure was estimated when the DC failure voltage was regarded as the HBM failure voltage.

The Health Belief Model - Is it relevant to Korea?

  • Lee, Mi-Kyung;Colin William Binns;Kim, Kong-Hyun
    • Korean Journal of Health Education and Promotion
    • /
    • v.2 no.1
    • /
    • pp.1-19
    • /
    • 2000
  • With rapid economic development, the emphasis of the public health movement in Korea has shifted towards addressing the burden of chronic disease. With this shift in direction comes a greater focus on health behaviour and the need for planning models to assist in lifestyle modification programs. The Health Belief Model (HBM), which originated in the US, has generated more research than any other theoretical approach to describe and predict the health behaviour of individuals. In recent years it has been applied in many different cultures and modifications have been suggested to accommodate different cultures. Given the centrality of language and culture, any attempts to use models of health behaviour developed in a different culture, must be studied and tested for local applicability. The paper reviews the applicability and suitability of the HBM in Korea, in the context of the Korean language and culture. The HBM has been used in Korea for almost three decades. The predictability of the HBM has varied in Korean studies as in other cultures. Overall, this literature review indicates that the HBM has been found applicable in predicting health and illness behaviours by Korean people. However if the HBM is used in a Korean context, the acquisition of health knowledge is an important consideration. Most new knowledge in the health sciences is originally published in English and less frequently in another foreign language. Most health knowledge in Korea is acquired through the media or from health professionals and its acquisition often involves translation from the original. The selection of articles for translation and the accuracy of translation into language acceptable in the Korean culture become important determinants of health knowledge. As such translation becomes an important part of the context of the HBM. In this paper modifications to the HBM are suggested to accommodate the issues of language and knowledge in Korea.

  • PDF

Systematic Review of Osteoporosis Preventive Intervention Studies based on Health Belief Model (건강신념모델 기반의 골다공증 예방 중재연구에 대한 체계적 문헌고찰)

  • Noh, Eun-Young;Ryu, So Im
    • Journal of muscle and joint health
    • /
    • v.30 no.2
    • /
    • pp.70-82
    • /
    • 2023
  • Purpose: This study aims to systematically clarify and enhance the understanding of osteoporosis prevention interventions based on Health Belief Model (HBM). The analysis includes HBM constructs, intervention characteristics, and outcomes from prior studies. Methods: We extensively searched eight electronic databases to identify peer-reviewed studies that implemented HBM-based interventions for osteoporosis prevention until June 2023. Results: Initially, 638 articles were identified, and after a rigorous evaluation process, 11 articles were included in the evidence synthesis. The analysis revealed that HBM-based interventions significantly improved likelihood of taking action including knowledge, HBM constructs and adopting preventive behaviors such as calcium intake and exercise. However, most interventions included in this study did not fully encompass all five HBM constructs or specify the particular components adopted. Conclusion: There is a need for additional research and intervention refinement for a more comprehensive understanding of osteoporosis preventive interventions. This should involve a concerted effort to incorporate all HBM constructs into the context of osteoporosis prevention. Thus, more effective interventions promoting optimal preventive behaviors and reducing the burden of osteoporosis can be developed.

Effects of Supplementary Cu-Soy Proteinate (Cu-SP) and Herbal Mixture (HBM) on the Growth Performance, Intestinal Microflroa, Immune Response in Broilers (Cu-Soy Proteinate(Cu-SP)와 Herbal Mixture(HBM)의 급여가 육계의 생산성, 소장 내 미생물 균총 및 면역체계에 미치는 영향)

  • Kim, Chan Ho;Shin, Kwang Suk;Kang, Hwan Ku;Kim, Ji Hyuk;Hwangbo, Jong;Choi, Hee Cheol;Moon, Hong Kil;Paik, In Kee;Bang, Han Tae
    • Korean Journal of Poultry Science
    • /
    • v.41 no.3
    • /
    • pp.165-171
    • /
    • 2014
  • The objective of this experiment was to investigate the effect of dietary supplementation of copper-soy proteinate (Cu-SP) and herbal mixture (HBM) on growth performance, intestinal microflora, and immune response in broiler. A total 1,000 1-d old ROSS 308 (initial $BW=41{\pm}0.38g$) were randomly allotted to 1 of 5 dietary treatments with 4 replicates during d 35 of the feeding trial. Dietary included: (1) Control : control diet, (2) Antibiotics : control diet + Avilamycin 6 ppm, (3) Cu-SP : control diet + 100 ppm Cu-soy proteinate, (4) HBM : control diet + 0.15% herbal mixture, (5) Cu-SP+HBM : control diet + 100 ppm Cu-soy proteinate + 0.2% herbal mixture. Two-phase feeding program with a starter diet from d 0 to 21, and a finisher diet from d 22 to 35 was used in the experiment. Within each phase, a diet was formulated to meet or exceed NRC requirements of broilers for macro- and micronutrients. The diet and water were available ad libitum. Result indicated that during d 22 to 35 and over all periods of the experiment, feed intake and feed conversion ratio were greater (P<0.05) for other treatment than control. Significant differences were found in lymphocyte (LY), and stress indicator (HE:LY ratio). Lymphocyte was greater (P<0.05) for Cu-SP + HBM treatment than control. However, stress indicator (HE:LY ratio) were greater (P<0.05) for control than Cu-SP + HBM treatment. The plasma IgG was higher (P<0.05) in the antibiotics, HBM, and Cu-SP+HBM treatments groups compared with control. The population of Clostridium perfringens in the antibiotics, Cu-SP, HBM, Cu-SP + HBM treatment groups were lower (P<0.05) than those control. These result suggested that dietary copper-soy proteinate or herbal mixture may be used as an alternative to antibiotics to improve growth performance, and intestinal health of birds.