• Proceedings of the Korea Concrete Institute Conference
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• 2006.05a
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• pp.562-565
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• 2006

Recently, the public interest for infrastructure safety has been growing, but the process of data acquisition and management system for safety is being carried out in an inefficient manner. The data obtained during the inspection for the safety of infrastructure tends to be documented using papers, which is not efficient in the stage of post analyses. The information technology (IT), which is rapidly being developed, is applied to the new system as a solution. Information technology provides valuable tools for converting and generating digital data, handling the history of defects, and assessing the condition and estimating the service life of infrastructure. The purpose of this paper is to introduce Infrastructure Management System(IMS). It is expected that the IMS would minimize the manpower, time and maintenance cost, and improve the safety of infrastructure.

• Korean Journal of Construction Engineering and Management
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• v.2 no.4 s.8
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• pp.92-97
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• 2001

The level of awareness and actual implementation of integration and computerization in the construction industry is growing. However, it is not clear at this point how to assess the extent of their impact and to identify in which ways they better support the construction projects related to their success. The objectives of this research are the development of a model to evaluate the impact of integration and computerization on construction projects and the recommendation of guidelines for companies in identifying suitable ways for them to incorporate integration and computerization Into their operation. The developed conceptual model has been found robust enough to be used as a benchmarking tool in evaluating the performance of the construction process and to strategize its future operation.

• Journal of the Korean Ceramic Society
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• v.47 no.1
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• pp.8-18
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• 2010

When metal oxides are exposed to chemical potential gradients, ions are driven to diffusive mass transport. During this transport process, the divergence of ionic fluxes offers the formation/annihilation of oxides. Therefore, the divergence of ionic flux may play an important role in the void formation in oxides. Kinetic equations were derived for describing chemical potential distribution, ionic fluxes and their divergence in oxides. The divergence was found to be the measure of void formation. Defect chemistry in scales is directly related to the sign of divergence and gives an indication of the void formation behavior. The quantitative estimation on the void formation was successfully applied to a growing magnetite scale in high temperature oxidation of iron at 823 K.

• 유체기계공업학회:학술대회논문집
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• 2000.12a
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• pp.176-183
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• 2000

The performance of gas turbines decreases as their operating hours increase. Compressor fouling is the main reason for this time-dependent performance degradation. Airborne particles adhere to the blade surface and results in the change in the blade shape. It is difficult to exactly analyze the mechanism of the compressor fouling because the growing process of the fouling is very slow and the dimension of the fouled depth is very small compared with blade dimensions. In this study, an analytic method to predict the motion of particles and their deposition inside axial flow compressors is proposed. The analytic model takes into account the blade shape and the flow within the blade passage. Comparison of simulation result with field data shows the feasibility of the model. Influence of the particle distribution on the compressor fouling is also examined.

• Proceedings of the IEEK Conference
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• 2003.07b
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• pp.863-866
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• 2003

Recently, there has been growing interests in the magneto-resistive random access memory (MRAM) because of its great potential as a future nonvolatile memory. In this paper, a CMOS macro-model for MRAM cell based on a twin cell structure is proposed. The READ and WRITE operations of the MTJ cell can be emulated by adopting data latch and switch blocks. The behavior of the circuit is confirmed by HSPICE simulations in a 0.35-${\mu}{\textrm}{m}$ CMOS process. We expect the macro model can be utilized to develope the core architecture and the peripheral circuitry. It can also be used for the characterization and the direction of the real MTJ cells.

• BMB Reports
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• v.42 no.6
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• pp.324-330
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• 2009

Autophagy is a bulk lysosomal degradation process important in development, differentiation and cellular homeostasis in multiple organs. Interestingly, neuronal survival is highly dependent on autophagy due to its post-mitotic nature, polarized morphology and active protein trafficking. A growing body of evidence now suggests that alteration or dysfunction of autophagy causes accumulation of abnormal proteins and/or damaged organelles, thereby leading to neurodegenerative disease. Although autophagy generally prevents neuronal cell death, it plays a protective or detrimental role in neurodegenerative disease depending on the environment. In this review, the two sides of autophagy will be discussed in the context of several neurodegenerative diseases.

• Biomedical Science Letters
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• v.20 no.4
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• pp.185-193
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• 2014

Cancers are based upon an array of orchestrated genetic changes and the identification of changes causally related to the carcinogenic process. To elucidate the mechanism of cancer carcinogenesis, it is necessary to reconstruct these molecular events at each level. Microarray technologies have been extensively used to evaluate genetic alterations associated with cancer onset and progression in clinical oncology. The clinical impact of the genomic alterations identified by microarray technologies are growing rapidly and array analysis has been evolving into a diagnostic tool to better identify high-risk patients and predict patient outcomes from their genomic profiles. Here, we discuss the state-of-the-art microarray technologies and their applications in clinical oncology, and describe the potential benefits of these analysis in the clinical implications and biological insights of cancer biology.

• BMB Reports
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• v.51 no.5
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• pp.211-218
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• 2018

Chromatin is an intelligent building block that can express either external or internal needs through structural changes. To date, three methods to change chromatin structure and regulate gene expression have been well-documented: histone modification, histone exchange, and ATP-dependent chromatin remodeling. Recently, a growing body of literature has suggested that histone tail cleavage is related to various cellular processes including stem cell differentiation, osteoclast differentiation, granulocyte differentiation, mammary gland differentiation, viral infection, aging, and yeast sporulation. Although the underlying mechanisms suggesting how histone cleavage affects gene expression in view of chromatin structure are only beginning to be understood, it is clear that this process is a novel transcriptional epigenetic mechanism involving chromatin dynamics. In this review, we describe the functional properties of the known histone tail cleavage with its proteolytic enzymes, discuss how histone cleavage impacts gene expression, and present future directions for this area of study.

• Neonatal Medicine
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• v.17 no.2
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• pp.155-160
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• 2010

Metabolic acidosis is commonly encountered issues in the management of critically ill neonates and especially of preterm infants during early neonatal days. In extremely premature infants, low glomerular filtration rate and immaturity of renal tubules to produce new bicarbonate causes renal bicarbonate loss. Higher intake of amino acids, relatively greater contribution of protein to the energy metabolism and mineralization process in growing bones are also responsible for higher acid load in premature infant than in adult. Despite widespread use of sodium bicarbonate in the management of severe metabolic acidosis, use of sodium bicarbonate in premature infants should be restricted to a reasonable but unproven exception such as ongoing renal loss. Despite concern about the low pH value (<7.2) which can compromise cellular metabolic function, no treatment guideline has been established regarding the management of metabolic acidosis in premature infants. Appropriately powered randomized controlled trials of base therapy to treat metabolic acidosis in critically ill newborn infants are demanding.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.11 no.12
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• pp.5694-5711
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• 2017

The technology of cloud computing is growing very quickly, thus it is required to manage the process of resource allocation. In this paper, load balancing algorithm based on honey bee behavior (LBA_HB) is proposed. Its main goal is distribute workload of multiple network links in the way that avoid underutilization and over utilization of the resources. This can be achieved by allocating the incoming task to a virtual machine (VM) which meets two conditions; number of tasks currently processing by this VM is less than number of tasks currently processing by other VMs and the deviation of this VM processing time from average processing time of all VMs is less than a threshold value. The proposed algorithm is compared with different scheduling algorithms; honey bee, ant colony, modified throttled and round robin algorithms. The results of experiments show the efficiency of the proposed algorithm in terms of execution time, response time, makespan, standard deviation of load, and degree of imbalance.