• Bulletin of the Korean Chemical Society
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• 제13권3호
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• pp.274-279
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• 1992

Immobilization method of lariat azacrown ethers, containing hydroxyl group in the side arm of crown ring, on the polymer matrix and the phase-transfer catalytic activity of thus obtained immobilized lariat azacrown ethers were studied. Polystyrene resins with crown ether structures and hydroxyl groups adjacent to the macrorings were prepared by the reaction of crosslinked polystyrene resins containing epoxy groups with monoaza-15-crown-5 or monoaza-18-crown-6. Microporous crosslinked polystyrene resins containing epoxy group for the syntheses of these immobilized lariat crown catalysts were prepared by suspension polymerization of styrene, divinylbenzene (DVB 2%) and vinylbenzylglycidyl ether. The immobilized lariat catalysts with 10-20% ring substitution exhibited maximal activity for the halogen exchange reactions of 1-bromooctane with aqueous KI or NaI under triphase heterogeneous conditions. Immobilized catalyst exhibited higher activity than corresponding catalyst without the hydroxyl group and this result was suggested that the active site have a structure in which the $K^+$ ion was bound by the cooperative coordination of the crown ring donors and the hydroxyl group in the side arm.

• Clinical and Experimental Reproductive Medicine
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• 제47권3호
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• pp.227-232
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• 2020

Objective: The aim of this study was to compare in vitro fertilization outcomes between fresh day 3 or day 4 embryo transfer cycles with dual progesterone (P) administration (intramuscular and vaginal) and cycles with single intramuscular P administration for luteal support. Methods: We selected 124 cycles from 100 women (under age 40 years) who underwent oocyte pick-up (number of trials ≤ 3, 4-14 oocytes obtained) and transfer of two or three day 3 or day 4 embryos at two infertility centers from January 2014 to June 2019. Dual P (intramuscular P [50 mg] daily+vaginal P) was used in 52 cycles and a single intramuscular administration of P (50 mg daily) was used in 72 cycles. Results: Women's age, infertility factors, number of oocytes retrieved, number of transferred embryos, and mean embryo score were similar between the dual P group and the single P group. Although the number of trial cycles was significantly higher (1.9 vs. 1.5), and the mean endometrial thickness on the trigger day (10.0 mm vs. 11.0 mm) was significantly lower in the dual P group, the implantation rate, clinical pregnancy rate, ongoing pregnancy rate, and miscarriage rate for both day 3 and day 4 transfers were similar between the two groups. Conclusion: In fresh day 3 or day 4 embryo transfer cycles, dual P administration did not demonstrate any clinical advantages. Intramuscular P alone appears to be sufficient for luteal support.

• 한국임상수의학회지
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• 제5권1호
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• pp.1-7
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• 1988

An observational study was conducted to evaluate the effect of anterior pituitary gonadtropin on super-ovulation in donors, embryo quality, development stage of embryo, transfer location, corpus luteum quality of recipient, ease of transfer and induced versus natural estrus on pregnancy rates. The data were collected from 451 non-surgical transfers of fresh and frozen bovine embryos. 1. The average number of CL, formed in ovaries which were stimulated with follicular stimulating hormone, and/or APG, were 11. 1${\pm}$1.21, 12.3${\pm}$1.84, respectively. The numbers of embryos recovered were 8.2${\pm}$1.35, 8.7${\pm}$ 1.39, and the numbers of transferable embryos were 6.4${\pm}$0.98. 6.6${\pm}$1.01. respectively. 2 There was no effect of spontaneous versus prostaglandin-induced estrus of recipients on pregnany rates of either fresh (61.5% vs. 59.5%) or previously frozen(54.5% vs. 58.5%) embryos. 3. There were significant differences(p<0.05) in pregnancy rates for embryo grade 1(63.6%), grade 2 (45.4%) and grade 3 (30.4％) in fresh group and for grade-1 (60.5%), grade-2 (47.8%) and grade-3 (18.1%) in previously frozen embryos. 4. The recipients transfered with embryo morulae were found to have a lower (p<0.05) pregnancy rates than those transfered with embryos of blastocyst in be th fresh and previously frozen embryos. 5. There was no significant difference between transfer locations in pregnancy rates using both fresh and frozen embryos. 6. Attempts to select recipients for high pregnancy rates on the basis of corpus luteum (CL) quality were performed. CL were classified into 3 quality grades, on the basis of size and prominence. Quality grades 1 and 2 group had higher (p<0.05) pregnancy rates than grade-3 group using both fresh and frozen embryos. 7 Ease of transfer was ranked to a scale of one to three on the basis of increasing difficulty (time required). Transfers ranted as ease score 1 and 2 had significantly higher (P<0.05) pregnancy pregnancy rates (45.8%, 66.6%) than ease score 3 (27.7%, 31.8%) using both fresh and frozen embryos respectively.

• 대한인간공학회지
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• 제25권4호
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• pp.93-101
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• 2006

This study examined whether there is a transfer effect to other joint angles and the angular specificity of muscle fatigue after 6 weeks of isometric training of the vastus medialis. Twenty subjects were randomly assigned to 30° and 90° knee flexion groups and were trained at 80% maximal voluntary isometric contraction(MVIC) three times a week for 6 weeks. The pre-and post-training values of the 80% holding time(endurance time) of MVIC, the Fatigue Index(FI), and the MVIC at 30°, 60°, and 90° were compared. After isometric training for 6 weeks, in the 30° knee flexion group, FI decreased significantly(p<0.05) only at 30°, which was the training angle; there was no change at other angles. By contrast, in the 90° knee flexion group, FI decreased significantly(p<0.05) at both the trained angle and at the other angles, indicating a transfer effect of training. MVIC did not increase significantly(p<0.05) at any trained angle in either the 30° or 90° knee flexion groups after 6 weeks of isometric training, neither did the 80% holding time of MVIC differ significantly compared with pre-training in either group. These findings suggest that training at 90° of knee flexion is more effective than training at 30° of knee flexion for obtaining a training transfer effect on muscle fatigue in the vastus medialis.

• 방사선산업학회지
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• 제5권1호
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• pp.47-54
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• 2011

In this study, we investigated to evaluate differential expression of genes encoding lipid transfer proteins (LTP) by acute and chronic gamma irradiation in rice. After acute and chronic gamma irradiation by 100 Gy and 400 Gy to rice plant, necrotic lesion was observed in the leaf blade and anthocyanin contents were increased. We isolated a total of 21 rice lipid transfer protein (LTP) genes in the TIGR database, and these genes were divided into four different groups on the basis of nucleotide sequences. The LTP genes also were classified as different four classes according to expression pattern using RT-PCR. Group A, B contained genes with increased expression and decreased expression in acute and chronic, respectively. Group C contained genes with contrasted expression pattern. Group D wasn't a regular pattern. But the specific affinity was not obtained between two grouping.

• 디지털콘텐츠학회 논문지
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• 제15권2호
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• pp.137-145
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• 2014

본 논문에서는 전송시간의 변화가 큰 네트워크 환경에서 이레이저 코딩을 이용한 종단간, M개의 패킷으로 구성된 긴급 메시지의 전달 지연 단축 기법을 제안한다. 제안된 기법에서는 전송할 M개의 긴급 패킷들을 g개의 패킷으로 구성된 b개의 그룹으로 분할하고, 각 그룹에 대하여 r개의 리던던시 패킷이 추가된 이레이저 코딩을 수행한 후 전송한다. 각 그룹은 g+r개의 패킷 중에서 g개의 패킷이 도착하면 복구가 되며, 모든 그룹이 목적지에 도착하면, 전체의 긴급 메시지가 전달된다. 이레이저 코딩을 적용하게 되면 전달 지연은 단축이 되나, 추가적인 패킷 전송 및 코딩과 디코딩과정으로 인한 비용이 발생하게 되므로, 이러한 추가적인 전송비용을 고려하여 제안 기법의 최적 그룹 수 및 리던던시 패킷의 수에 대한 분석을 수행한다. 분석 결과로부터 제안된 기법은 전송시간의 변화가 큰 네트워크에서 큰 효과를 내며, 특히 긴급한 메시지의 전송이 필요할 때 유용함을 알 수 있다.

• 한국광학회지
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• 제17권6호
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• pp.514-518
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• 2006

높은 안정도를 가지는 100 MHz의 RF 신호를 23 km의 광섬유망을 통하여 전송하였다. 진동과 온도 변화에 의하여 생기는 광섬유 전송과정에서의 위상 잡음을 측정하고 이를 보상하는 회로를 구성하였다. 광섬유 잡음이 제거되었을 때, RF 신호 전송의 상대주파수 불안정도는 1초 평균시간에서 $6{\times}10^{14}$, 10000초 평균시간에서 $2{\times}10^{-17}$으로서 기준 RF 신호의 안정도와 거의 같은 수준으로 광섬유를 통하여 RF를 전송할 수 있었다. 잡음 보상에 의하여 단측파대 위상잡음은 푸리에 주파수 1 kHz 이하에서 20 dB 이상 감소하였다.

• 한국발생생물학회:학술대회논문집
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• 한국발생생물학회 2003년도 제3회 국제심포지움 및 학술대회
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• pp.109-109
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• 2003

Even though success in birth of live offspring from nuclear transfer(NT) using somatic cells in many species, detailed information on processes or mechanisms of development are not well known. Cytoplasm of bovine oocyte has been known to support the development of nuclear transferred embryos using nuclear donor cells from different species. Therefore, interspecies NT might be used to find answers of some questions in basic aspect of nuclear transfer In this study, we examined the developmental potential of reconstructed embryos when bovine oocyte as a cytoplasm recipient and mouse embryonic fibroblast as a nuclear donor were used. The nuclear transfer units were aliocated in Group 1 (murine block media and normal media) and Group 2. (bovine block media and normal media). NT units were not blocked at 2-cell stage regardless of types of medium. On mouse media, poor development of interspecies NT units was observed compared to bovine media. However, as NT units cultured in bovine normal medium, embryos developed over 8-cell stage. Further studies performed to increase the developmental rate in condition of antioxidant treatment. Despite low development, bovine-murine interspecies nuclear transferred embryos could develop to blastocysts and they showed that blastocyts rate of antioxidant group was superior to those of non-antioxidant group. Next, we investigated gene expression pattern which is carried out for zygotic activation. The Xist gene is expressed in female mouse embryo after zygotic activation of 4-cell stage. But interspecies nuclear transferred embryos do not express Xist gene at 4-cell stage. As a result, it is suggested that the bovine cytoplasm controls the early preimplantation development in interspecies NT However, the development of later stages might require genomic control from transferred donor nucleus. Therefore, even though the involvement of several other factors such as mitochondrial incompatibility, effective development of embryos produced by interspecies NT requires proper genomic activation of donor nucleus after overcoming the cytoplasmic control of recipient oocytes.

• 한국수정란이식학회지
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• 제21권4호
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• pp.307-313
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• 2006

본 연구에서는 수정란 이식을 위해 선발된 대리모에 이식 전 백신의 투여 시기가 임신과 유산에 미치는 효과와, 임신한 대리모의 분만 예정일 전에 백신의 투여가 송아지의 질병과 생존에 미치는 효과를 검토하였다. 실험 1에서는 한우 체외 수정란의 이식에 선발된 대리모의 백신 투여 시기가 임신과 유산에 미치는 영향을 검토하였다. 이식 전 $0{\sim}4$주째 백신 투여시 임신율이 31.5%로서 대조군 및 $4{\sim}8$주 투여군의 42.4 및 45.9%에 비하여 유의하게 낮았다(p<0.05). 유산율은 대조군과 처리군에서 4.9$\sim$13.5%로서 유사한 경향이었다. 실험 2에서는 체외 수정란을 이식하여 임신한 대리모에 백신 투여 시기가 송아지의 질병과 폐사에 미치는 효과를 검토하였다. 질병 발생율은 백신을 투여하지 않은 대조군이 22.4%로서 백신을 투여한 처리군의 2.2$\sim$3.1%보다 유의하게 높았다(p<0.05). 폐사율도 대조군이 27.6%로서 처리군의 11.1 및 7.8%와 유의차가 인정되었다(p<0.05). 폐사한 송아지의 원인은 사산이 15.4%, 난산 30.8%, 기형 3.8% 및 질병 50.0%였고, 질병으로 폐사한 송아지에서는 위장관 질병이 46.2%, 호흡기 질병이 7.6%였고 원인 불명이 46.2%였다.

• Journal of Korean Biological Nursing Science
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• 제20권2호
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• pp.132-140
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• 2018

Purpose: This study has been carried out in order to develop and verify the effects of self-leadership reinforcement program for hospital nurses. Methods: The research design was a non-equivalent control group pre-posttest design. Participants were 64 individuals (32 in each group), all of whom were nurses working at a university hospital, with less than five years of job experience. Experimental group was provided with two hours of self-leadership reinforcement program, once per week, for four weeks. The questionnaire for pre and post test included general characteristics, transfer motivation for learning, self-leadership, communication ability, clinical nursing competency, organizational commitment, and turnover intentions. Results: There was a significant difference in self-leadership scores between experimental group and control group (F= 15.10, p<.001). There was also a significant difference between the experimental group and the control group in terms of transfer motivation for learning (t = -5.44 p<.001), communication ability (F = 15.29, p<.001), clinical nursing competency (F = 15.23, p<.001), and organizational commitment scores (F = 7.21, p=.009). Conclusion: The self-leadership reinforcement program developed in this study was effective in improving self-leadership, communication ability, clinical nursing competency, and organizational commitment. Thus, by implementing the program at clinical levels, it will be a basis for nursing personnel resource administration.