• Journal of the Korean Society of Food Science and Nutrition
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• v.43 no.6
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• pp.799-806
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• 2014

The present study was conducted to evaluate the effects of extract from Eriobotrya japonica leaves (EJE) on cognitive impairment induced by scopolamine, a muscarinic antagonist, in rats. Scopolamine injection (1 mg/kg, i.p.) impaired performance in rats in the passive avoidance test as well as in water maze test and severely reduced cholinergic system reactivity, as indicated by reduced acetylcholine levels and increased acetylcholinesterase activity. Daily administration of EJE significantly increased step-through latency in the passive avoidance test, reduced escape latency, and increased time spent in the platform quadrant in the Morris water maze test. EJE protected against scopolamine-induced cholinergic system deficit, including reduced acetylcholine levels and increased acetylcholinesterase activity in whole brain homogenates. These results suggest that EJE provides a significant anti-amnesic effect against scopolamine-induced cholinergic system deficits and cognitive impairment.

• Journal of The Korean Society of Integrative Medicine
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• v.8 no.2
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• pp.199-209
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• 2020

Purpose : This study used a sarcopenia diagnostic algorithm proposed by the Asia working group in adults over 50 to diagnose sarcopenia and analyze body function. The purpose of this study is to prepare basic data for the management and prevention of sarcopenia. Methods : We performed a diagnostic evaluation of sarcopenia in 97 adults over the age of 50 years with the cooperation of the Seongnam senior experience complex in Seongnam-si, Gyeonggi-do. As a result of the diagnostic process, 24 subjects were placed into the sarcopenia group, while 73 subjects were placed into the normal group. We measured each subject's body, performed the timed up and go test to evaluate functional mobility, and conducted a questionnaire on the pre-symptom of locomotive syndrome and locomotive syndrome. Results : There were statistically significant differences in height, weight, and skeletal muscle mass between the two groups. There was also a statistically significant difference in the timed up and go test, which confirmed the difference in functional mobility between the two groups. In addition, there was a statistically significant difference between the two groups in the proportion and the mean score of subjects with pre-symptom of locomotive syndrome and locomotive syndrome. In the correlation analysis, grip strength was statistically significantly correlated with height, weight, skeletal muscle mass, waist circumference, timed up and go test, pre-symptom of locomotive syndrome and locomotive syndrome. Gait speed was significantly correlated with the timed up and go test and locomotive syndrome. Appendicular skeletal muscle index was significantly correlated with height, weight, waist circumference, hip circumference, and the pre-symptom of locomotive syndrome. Conclusion : In conclusion, sarcopenia is closely related to height, weight, skeletal muscle mass and functional mobility, as well as the pre-symptom of locomotive syndrome and, locomotive syndrome. In consideration of this, the prevention and management of sarcopenia should be made accordingly.

• Korean Journal of Social Welfare
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• v.66 no.4
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• pp.5-23
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• 2014

This study performed a series of analyses to examine the effects of regular exercise on depression using data from the HAS (Hallym Aging Study) and the KLoSA(Korean Longitudinal Study of Ageing). The effect of regular exercise on depression was tested through propensity score matching methods. In addition, analyses of five indirect effect models were performed to verify a theoretical description about how regular exercise has an effect on depression. The results of analysis were as follows. First, it was found in the two samples that elderly people who exercise regularly have a lower level of depression compared to those who do not. Second, the results of analysis of five indirect effect models were all significant. The psycho-physiological models showed the effect of regular exercise on depression using ADL(Activities of Daily Living) and grip strength. The psycho-social models also demonstrated the effect of regular exercise on depression using variables related to social activities. Based on these findings, intervention strategies to prevent depression was discussed.

• Journal of Music and Human Behavior
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• v.11 no.1
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• pp.1-19
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• 2014

The purpose of this study was to investigate the immediate effect of Patterned Sensory Enhancement (PSE) technique on the motor function of the affected upper limb in hemiplegic stroke patients by comparing the use of PSE and simple rhythmic cue. A total of 16 stroke patients were recruited from rehabilitative hospitals. The participants were assigned to the experimental group (n = 8) and control group (n = 8). While performing six different upper limb motions, musical stimuli applying the PSE technique was presented for the experimental group and simple rhythmic cue using the metronome was applied for the control group. The results showed that while the significantly increased range of motion (ROM) was found in the experimental group with the immediate use of PSE (p < .05), the control group did not show no significant change. This study implies that the use of musical elements in cueing for upper limb motion immediately leads to significant improvement in ROM by providing sufficient temporal, spatial, and dynamic information for expected motor performance.

• Journal of Digital Convergence
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• v.11 no.11
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• pp.553-560
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• 2013

The purpose of this study was to examine the effect of u-health system on metabolic syndrome risk factor, body composition, and fitness in male and female elderly. Subjects were 46 elderly(24 men and 22 women) with metabolic syndrome. They were divided into u-health group and home exercise group. Blood pressure, blood profile, body composition, and fitness were measured before and after the intervention. As a results, blood glucose and waist circumference showed significant interaction in both men and women, respectively. In body composition, weight, muscle mass, fat mass, %body fat, BMI showed significant interaction whereas only muscle mass showed significant differences in women. In fitness, there were interaction shown in 3m up and go, functional reach, and gait speed in men. In women sit to stand, 6min walk, and grip strength showed significant interaction. In conclusion, u-health system seems to be the effective method in terms of checking regularly. However, easier and more simple system for elderly and specific direction for exercise should be added.

• Korean Journal of Community Nutrition
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• v.24 no.6
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• pp.525-534
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• 2019

Objectives: Reduced glucose utilization in the main parts of the brain involved in memory is a major cause of Alzheimer's disease, in which ketone bodies are used as the only and effective alternative energy source of glucose. This study examined the effects of a low-carbohydrate and high-fat (LCHF) diet supplemented with a ketogenic nutrition drink on cognitive function and physical activity in the elderly at high risk for dementia. Methods: The participants of this study were 28 healthy elderly aged 60-91 years showing a high risk factor of dementia or whose Korean Mini-Mental State Examination (K-MMSE) score was less than 24 points. Over 3 weeks, the case group was given an LCHF diet with nutrition drinks consisting of a ketone/non-ketone ratio of 1.73:1, whereas the control group consumed well-balanced nutrition drinks while maintaining a normal diet. After 3 weeks, K-MMSE, body composition, urine ketone bodies, and physical ability were all evaluated. Results: Urine ketone bodies of all case group subjects were positive, and K-MMSE score was significantly elevated in the case group only (p=0.021). Weight and BMI were elevated in the control group only (p<0.05). Grip strength was elevated in all subjects (p<0.01), and measurements of gait speed and one leg balance were improved only in the case group (p<0.05). Conclusions: We suggest that adherence to the LCHF diet supplemented with a ketogenic drink could possibly influence cognitive and physical function in the elderly with a high risk factor for dementia. Further, we confirmed the applicability of this dietary intervention in the elderly based on its lack of any side effects or changes in nutritional status.

• Journal of the Korea Convergence Society
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• v.9 no.3
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• pp.111-119
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• 2018

This study was conducted to evaluate the converge effects of the Be Happy and Strong (BeHaS) exercise program on female elders living alone, using a nonequivalent control-group pretest-posttest design. The BeHaS exercise program was conducted twice each week for 4 weeks (total 8 sessions). The outcome measures included pain, shoulder flexibility, grip strength, depression, and suicidal ideation. Independent t-test, Chi-squre test, paired t-tests and ANCOVA were used for the statistical data analysis. A statistically significant improvement emerged in pain (t=4.044, p=.000) and right and left shoulder flexibility (t=2.192, p=.038 and t=2.568, p=.016) 4 weeks later. In a group comparison, a statistically significant difference arose in changed scores of suicidal ideation (F=7.32, p=.010) between groups. The BeHaS exercise program may effectively improve the physical and psychological health of female elders living alone.

• Journal of Korean Orthopaedic Sports Medicine
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• v.3 no.2
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• pp.134-140
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• 2004

Purpose: The reconstructive surgery of the anterior oblique ligament has been recommended for patients with unstable carpometacarpal joints. We reviewed retrospectively the functional results of two patients who had been treated by6 using a harvested portion of the tendon of flexor carpi radialis as a substitute for the anterior oblique ligament. Materials and Methods: In two patients with a instability of the trapeziometacarpal joint because of a rupture of the anterior oblique ligament, reconstruction was carried out using a slip of the tendon of flexor carpi radialis and the patients had been followed up for two years. Results: The results after a follow-up of two years that both of them had significant relief from pain and symptoms. The mean grip strength recovered to 90$\%$ of the controlateral side. patients felt that they had subjective improvement and would have undergone the operation again. Conclusion: Increased awareness of this lesion can lead to an early and clear diagnosis, so that the patient may be advised adequately.

• Journal of muscle and joint health
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• v.14 no.2
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• pp.127-136
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• 2007

Purpose: There has been a need to integrating the self-help program for arthritis with the TaiChi for arthritis patient. The purpose of this study was to develop and to examine the effect of the Self-help and Tai Chi for arthritis (SHTCA) program for arthritis. Method: This study was designed non equivalent control group pre-post test, quasi-experimental design. A total 40 participants were recruited in W-city, 29 participants(14-experimental group and 15-control group) completed post test. The experimental group participated in the SHTCA once a week for 8 weeks. SHTCA program was consisted of understanding of the arthritis, contracting of the promise, exercise for muscle strength and joint flexibility and 8 movements of Tai Chi exercise. Coloring plus program to cellular phone was used to encourage the exercise and participation by the KT-SHUT twice a week. Measures used to examine the effect of the SHTCA were EQ-5D standardized five dimensions(mobility, self-care, usual activities, pain & discomfort, and anxiety & depression), and health perception, joint flexibility, grasping power, and balance. Collected data was analyzed by SPSS WIN 14.0. Results: The experimental group had significantly increased the EQ-mobility(p=.033), health perception(p=.000), right shoulder flexibility(p=.007), and left shoulder flexibility(p=.002) compared to the control group. In addition, pain was decreased(p=.052) and right grip was increased(p=.052) after 8 weeks program in the experimental group. Conclusion: This SHTCA using coloring plus program was found partially effective and satisfactory. We recommended further research on the effect of this SHTCA effects.

• Journal of the Korean Applied Science and Technology
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• v.38 no.4
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• pp.1081-1092
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• 2021

The purpose of the study was to examine the effects of the 16-week combined exercise on the blood dopamine concentrations, functional fitness and QOL in patients with parkinson's disease. To this end, 24 persons parkinson's disease in over 60 years old who participated in this study were classified in to the exercise group(n=12) and control group(n=12), and then the exercise group was twice a week for 16-weeks, 70 min per session combined exercise was applied. The test dada were analyzed by two-way repeated measures ANOVA, paired t-test, and independent t-test. The alpha level of .05 of significance. As a result, first, parkinson's disease who regularly participated in the combined exercise significantly increased blood dopamine concentrations(p<.001). Second, parkinson's disease who regularly participated in the combined exercise significantly improved grip strength(p<.001), arm curl(p<.001), stand up and sit down a chair(p<.001), 3m walk and come back(p<.01). Third, parkinson's disease who regularly participated in the combined exercise significantly improved QOL(p<.001). Thus, the combined exercise had the positive effects and may be helpful to increased the blood dopamine concentration and improved functional fitness and QOL.