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The Effect of Sea Tangle Supplementation and Exercise Training on Blood Glucose and Lipid Profile in Rats (다시마 보충과 운동훈련이 흰쥐의 혈당과 혈중지질에 미치는 영향)

  • Hwang, Hye-Jin;Kwak, Yi-Sub;Kim, Hyang-Suk;Choi, Yung-Hyun;Kim, Byung-Woo;Kwon, Hyun-Ju;Yoon, Byung-Kon
    • Journal of Life Science
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    • v.20 no.5
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    • pp.805-810
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    • 2010
  • The purpose of this study was to investigate the effect of Sea Tangle supplementation and exercise training on blood glucose and lipid profile in rats. Twenty seven, 4-week old male Sprague-Dawley rats were divided into the control group (C, n=9), sea tangle group (D, n=9) and sea tangle+exercise group (D+T, n=9). Exercise training was performed 5 days a week using a treadmill running program for 6 weeks (5 m/min, 0% grade, 30 min). There was no difference in blood glucose (C: $175.9{\pm}47.5$, D: $173.9{\pm}34.0$, D+T: $165.0{\pm}38.0\;mg/dl$) and triglyceride (C: $251.1{\pm}91.8$, D: $215.0{\pm}90.0$, D+T: $200.0{\pm}89.3\;mg/dl$) among the groups. Total cholesterol value of the D+T group ($81.8{\pm}11.2\;mg/dl$) was significantly lower than that of the C ($103.0{\pm}13.5\;mg/dl$) and D ($102.1{\pm}14.5\;mg/dl$) groups. High density lipoprotein cholesterol (HDL-C) was significantly high in the D+T ($40.9{\pm}9.7\;mg/dl$) group compared with the C ($32.6{\pm}3.8\;mg/dl$) group and D ($31.7{\pm}7.3\;mg/dl$) group. The value of low density lipoprotein cholesterol (LDL-C) for the D ($98.0{\pm}41.0\;mg/dl$) group was statistically lower than the C($114.5{\pm}41.8\;mg/dl$) group, and higher than the D+T ($91.2{\pm}41.7\;mg/dl$) group. In conclusion, sea tangle injection and exercise had a positive effect on blood lipid profiles.

Clinicopathologic Profile of Breast Cancer Patients in Pakistan: Ten Years Data of a Local Cancer Hospital

  • Khokher, Samina;Qureshi, Muhammad Usman;Riaz, Masooma;Akhtar, Naseem;Saleem, Afaf
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.2
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    • pp.693-698
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    • 2012
  • Breast cancer is the most frequent cancer of women worldwide, with considerable geographic and racial/ethnic variation. Data are generally derived from population based cancer registries in the developed countries but hospital data are the most reliable source in the developing countries. Ten years data from 1st Jan 2000 to 31st Dec 2009 of a cancer hospital in Pakistan were here analyzed by descriptive statistics to evaluate the clinicopathologic profile of local breast cancer patients. Among 28,740 cancer patients, 6,718 were registered as breast cancer. The female to male ratio was 100:2. Breast cancer accounted for 23% of all and 41% of female cancers. Some 46% were residents of Lahore, with a mean age of $47{\pm}12$ years. Less than 1% were at Stage 0 and 10%, 32%, 35% and 23% were at Stage I, II, III and IV respectively. Histopathology was unknown in 4% while 91%, 2% and 1% had invasive ductal carcinoma (IDC), invasive lobular carcinoma (ILC) and mucinous carcinoma respectively. Rare carcinomas accounted for the rest. Tumor grade 1, 2 and 3 was 11%, 55% and 34% among the known. Profile of breast cancer patients in Pakistan follows a pattern similar to that of other developing countries with earlier peak age and advanced disease stage at presentation. The male breast cancer accounts for higher proportion in the local population. Local women have higher frequency of IDC and lower frequency of ILC and DCIS, owing probably to a different risk profile. Use of hospital information systems and establishment of population based cancer registry is required to have accurate and detailed local data. Promotion of breast health awareness and better health care system is required to decrease the burden of advanced disease.

A Study on the Mining Method for Limestone Mines with Less Environmental Hazards (환경오염 저감을 위한 석회석 광산개발방안에 대한 연구)

  • 임한욱;김재동;백환조
    • Tunnel and Underground Space
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    • v.10 no.1
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    • pp.80-91
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    • 2000
  • Open cut mining of limestone is generally considered to be more advantageous than underground mining in recovery, grade control, economics, and safety, but it causes substantial environmental pollutants such as ground vibration, noise, dust. It also changes ground surface and may destroy vegetation. The Halla limestone mine which lies adjacent to Baikdu mountains range is selected for a model study. To reduce environmental hazards, and to conserve original surface and woods, both open cut and underground mining methods must be adopted. In case of sub-level sloping. a unit block of 87m high, 70m wide, and 100∼l20m long is suggested with an estimated overall recovery of 42%. Some suggestions to reduce the environmental hazards are also included. The followings must be considered in determining the degree of fragmentation; the discontinuity conditions in the rock mass and the charge concentration both at the bottom and column of the hole. In addition to adopting a barrier wall for reducing environmental hazards, the probable production from underground mining is also discussed.

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Free Rectus Muscle or Myocutaneous Flap for Reconstruction on the Various Sites (다양한 부위의 재건에 있어 유리복직근 피판술의 이용)

  • Ahn, Ki-Young;Lee, Jae-Wook;Han, Dong-Gil
    • Archives of Reconstructive Microsurgery
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    • v.5 no.1
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    • pp.80-91
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    • 1996
  • A free rectus abdominis flap can include a variable amount of muscle length depending on recipient site requirements. There is also great flexibility in flap design in terms of size, orientation of its axis, and the level of its location over the muscle. It is safe to design the skin island across the midline. Though skin islands designed over the most inferior portion of the abdomen have not always proved reliable when based on the superior epigastric artery, free flaps based on the inferior pedicle can be successfully designed in this area. As free flap based on the inferior epigastric vessels, this flap has been useful for large head and neck defects following ablative procedures, for facial contour restoration as a buried flap, for upper extremity defects, for lower extremity defects such as coverage of grade III tibial fractures and for breast reconstruction. A free rectus abdominis muscle or myocutaneus flap was used in 8 patients. The operations were performed between Sep. of 1994 and April of 1996. The patients were tongue cancer 1 case, chronic facial palsy 1 case, unilateral breast reconstruction 1 case, upper and lower extremity injury 5 cases. The free rectus abdominis muscle flaps were 4 cases and the free myocutaneous flaps were 4 cases. There was no failure of the flap, except one partial necrosis. One case of the skin grafts on the muscle flap was regrafted. One case of reoperation due to venous thrombosis was performed. In tongue cancer patient, a orocutaneous fistula was occurred, but conservative treatment and secondandry skin graft were done. In conclusion, a free rectus abdominis flap has many advantages such as a long and constant pedicle, easy dissection, enough soft tissue available, scar on the donor site to be hiddened, no need for changing position. So we think that this flap is the most useful one for small or moderate sized defects on the various sites.

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Nutritional Survey on the Children Lunch-Box of Primary School in Junbuk Province (전북지방(全北地方) 국민학교(國民學校) 학생(學生)의 도시락 영양실태조사(營養實態調査))

  • Choe, Sun-Nam
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.11 no.2
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    • pp.13-20
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    • 1982
  • The primary purpose of this research paper is to study the nutrition intake status of primary school children and their physique index. Three hundred and ten children of 4th grade, 10 years old, 4 school class in Junbuk province had been selected. Calorie and nutrients were found to be below the recommended level, especially in calcium an vitamin $B_2$. Animal-protein intake averaged about 33% of total protein intake. Total calorie intake were composed of 84% from carbohydrate, 5% from fat and 11% from protein in the case of boys. The girls were 83%, 6%, 11%, respectively. The staple of lunch-boxes for boys supplied 84% of RDA in calorie, 66%, in total-protein 38%, calcium, 32%, Iron, 56%, vitamin $B_1$, 37%, vitamin $B_2$ and 63%, in niacin for girls were 82%, 52%, 28%, 37%, 39%, 37%, 51% respectively.

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A Study on Adjustment of Daily Living and Body Image of Patients with Low Back Pain (요통환자의 신체상과 생활적응에 관한 연구)

  • 구희서
    • Korean Journal of Health Education and Promotion
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    • v.6 no.1
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    • pp.91-105
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    • 1989
  • The purpose of this study is to identify the body images of patints with low back pain and their status on adjustment of daily living. The data were collected from 11 general hospitals during Feburary 2, 1987 through May 30,1987. One hundred and ninety five subjects having physical therapy treatment because of low back pain were analyzed. For measurement of body image, 11 pairs of adjectives were used on semantic differential scale, and for measurement of adjustment of daily living, 10 items were used on a likert type scale. Results of the study are summerised as follows. 1. The average patient age were 34yeats and 62% of the patients were men. High school grade completed were 43.1% and Cause of Low Back Pain were respctively;Unknown etiology 31.8%, lifting heavy objects 27.7%, Traffic accident and injury 17.9%. Types of treatment were;medication plus physical therapy 54.9%, physical therapy only 22.6%. Average treatment duration were 24.5 months. 2. There were significant difference in the body image between before low back pain and after low back pain. The body image before low back pain were 59.89(Mean) but after low back pain were 37,24(Mean) and two groups were statistically significant (t=21.3, p<0.00l). 3. there were no significant difference in the body image between the male and female.(t=1.49, p>0.05) 4. The correlation between body image and adjustment of daily living. in both sexes showed positive correlation coefficient; male(r=0.4648, p<0.00l) female(r=0.4516, p<0.00l) respectively. It means that patients with positive body image can adjust well in daily living. 5. The relation between the body image and general variables revealed sigificant difference with occupation and age.(F=2.12 p<0.05, F=3.48 p<0.05). That is different occupation and different age groups can show different body image. In conculsion with the above results, It is my strong belief that multidisciplinary approach including the concept of body image and patient education about postural care, activities of daily living, lifting mechanics should be applied in treating and dealing with those patients.

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A Survey of Pharmacy Students' Perceptions of National Drug Supply Strategy through Public Pharmaceutical Companies (약학대학 학생들의 공공제약사를 통한 국가의 의약품공급 전략에 대한 인식 조사)

  • Jeon, Sung Ryul;Ha, Jung Eun;Sohn, Hyun Soon
    • Korean Journal of Clinical Pharmacy
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    • v.27 no.4
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    • pp.238-249
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    • 2017
  • Background: Currently establishment of public pharmaceutical companies became an issue for securing stable supply of national essential drugs in order to respond appropriately to national public health crisis. Pharmacy students as future pharmacists need to be interested in drug related issues under the discussion in our society. This study aimed to investigate perceptions of pharmacy students on the national drug supply strategy through public pharmaceutical companies. Methods: A 20-items questionnaire designed for this study was used. Pharmacy students nationwide were enrolled in July 2017. They responded to questions through on-line survey program. Data were analyzed descriptively. Results: 160 students from 26 pharmacy schools participated. 5th and 6th grade students accounted for two-thirds, and one third aspired future jobs in pharmaceutical industry. Among responders, 71.3% was unaware of current national essential drugs, 52.5% did not know the Rare and Essential Drug Center, and 91.9% was unaware of the legislation on the supply and management of essential drugs. 82.5% favored the establishment of public pharmaceutical companies. 80.6% agreed that government should intervene in pharmaceutical market for ensuring drug accessibilities, 73.8% agreed that public pharmaceutical companies make possible to reach a goal of stable supply of pharmaceuticals, and 85.1% agreed that active compulsory license by public pharmaceutical companies is necessary. Conclusion: We found that pharmacy students recognized the need for governmental control to achieve social values of pharmaceuticals. More attention and participation of the pharmacy students as well as pharmacists in the process of national debate on public pharmaceutical companies are expected.

A Study on Elementary School Teacher's Status and Recognition of Nutrition Education in Incheon (인천지역 초등학교 교사의 영양교육 실태 및 인식에 관한 연구)

  • Park Jeong Ah;Chang Kyung Ja
    • Journal of Nutrition and Health
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    • v.37 no.10
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    • pp.928-937
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    • 2004
  • The purpose of this study was to investigate the elementary school teacher's status and recognition of nutrition education (NE) in Incheon. A cross-sectional study was carried out using a self-administered questionnaire and subjects were 147 elementary school teachers. The results are as follows. Only 9.5% of the teachers had training in NE and 71.4% of the teachers with training increased concern about NE after training. As for experience of NE, 61.6% of the teachers experienced NE and more than half of them gave NE less than twice per month. There was a significant difference in reason for not giving NE between subgroups by teaching career; 57.7% of the teachers with career more than 10 years did not give NE due to too much other work. As for existence of nutrition educator in school, 48.9% of the teachers recognized its existence and 91.3% of them answered that dietitians have done NE. For correction of unbalanced diet, good table manner, and nutrition and growth, 97.9% of the teachers answered that NE is necessary in elementary school. As for proper time to start NE, 57.5% of the teachers answered kindergarten and 39,7% answered lower grade of elementary school. As for effective type for NE, 47.3% of the teachers answered NE as a part of other subject and 28.1 % answered NE as a separate subject. Also 69.8% of the teachers answered dietitian as suitable person for NE. As for newly establishing a NE subject, 37.9% of the teachers disagreed and as for most effective method for NE, 73.3% answered NE linked with school lunch program. Most of teachers recognized elementary school students' eating habit problem severe and change of their eating habit such as various food choice, no plate waste and good table manner after school lunch program. Therefore, it should be nationally supported that a standardized NE program is developed and coordinated among teachers, school lunch dietitian as NE specialist, family and community for elementary students' health and well-being.

Development of a Cost-Effective Process for the Fabrication of Single Grain $YBa_2Cu_3O_{7-y}$ Bulk Superconductors (단결정 $YBa_2Cu_3O_{7-y}$ 벌크 초전도체 제조를 위한 경제적 공정의 개발)

  • Park, Soon-Dong;Kim, Kwang-Mo;Jun, Byung-Hyuk;Han, Young-Hee;Kim, Chan-Joong
    • Progress in Superconductivity
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    • v.13 no.2
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    • pp.133-138
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    • 2011
  • To reduce the processing cost of the single grain REBCO (RE: Rare-earth elements) bulk superconductors, a cost-effective process should be developed. One possible way of developing the cost-effective process is the use of low-cost precursor powders. In this study, the single grain YBCO superconductors were fabricated using a home made powder. $YBa_2Cu_3O_{7-y}$ (Y123) powders were synthesized at $850-900^{\circ}C$ in air by the powder calcination method with repeated crushing and heat treatment steps. The processing parameters for the fabrication of single grain Y123 bulk superconductors, $T_{max}$ (maximum temperature), $T_p$ (peritectic temperature) and a cooling rate through $T_p$ were optimized. To enhance the flux pinning capacity of the single grain Y123 samples, $Y_2BaCuO_5$ (Y211) particles were dispersed in the Y123 matrix by adding $Y_2O_3$ powder to the calcined Y123 powder. Applying the optimized processing condition, the single grain Y123 superconductors with $T_c=91\;K$ and $J_c=1.5{\times}10^4\;A/cm^2$ at 2 T were successfully fabricated using a home made powder. The levitation forces and trapped magnetic field at 77 K measured using a Nd-B-Fe permanent magnet of 5300 G were 47 N and 3000 G, respectively, which are comparable to those obtained for the samples fabricated using a commercial grade Y123 powders.

Double blind randomized control trial to evaluate the efficacy of ketoprofen patch to attenuate pain during venous cannulation

  • Kumar, Sanjay;Sanjeev, Omprakash;Agarwal, Anil;Shamshery, Chetna;Gupta, Rakhi
    • The Korean Journal of Pain
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    • v.31 no.1
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    • pp.39-42
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    • 2018
  • Background: Venipuncture pain is an uncomfortable suffering to the patient. It creates anxiety, fear and dissatisfaction. The ketoprofen transdermal patch is a proven treatment for musculoskeletal and arthritic pain. We planned this study to evaluate the efficacy of the ketoprofen patch to reduce venipuncture pain. Methods: Two hundred adult patients, aged 18-60 years, of either sex, ASA grade I or II, were enrolled. Presuming that therapy would decrease venipuncture pain by 30%, a power calculation with ${\alpha}=0.05$ and ${\beta}=0.80$ required enrollment of at least 24 patients into each group. However, 100 patients in each group were recruited. Group I (Control) received a placebo patch; Group II (Ketoprofen) received a 20 mg ketoprofen patch. A selected vein on the dorsum of the patient's non-dominant hand was cannulated with 18 g intravenous cannula 1 h after the application of the respective patch. Assessment of pain was done by a 10 cm visual analogue scale (VAS) of 0-10, where 0 depicts "no pain" and 10 is "the worst imaginable pain". The venipuncture site was assessed for the presence of skin erythema, swelling and rashes at 12 h, 24 h and at the time of decannulation. Results: Incidence of pain was 100% (94/94) in the control group as compared to 93% (85/91) in the ketoprofen group. The severity of the venipuncture pain was 6 (2) and 2 (2) for control and ketoprofen groups respectively (P < 0.05). Conclusions: Application of a ketoprofen patch at the proposed site of venipuncture one hour before the attempt is effective and safe for attenuating venipuncture pain.