• Journal of the Korean Society of Food Science and Nutrition
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• v.42 no.12
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• pp.1899-1907
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• 2013

We investigated the effects of unripe black raspberry water extract (UBR-W) and oxidation-LDL treatment on cholesterol levels. Experiments using an established human hepatocellular carcinoma cell line (HepG2) showed a time-dependent increase in expression of LDL receptor after UBR-W treatment. Expression of LDL receptor-related genes, such as SREBP1 and 2, increased upon UBR-W treatment. However, expression of HDL-related genes was unaffected by UBR-W. HMG-CoA reductase activity was reduced by UBR-W treatment, whereas HMG-CoA mRNA expression significantly increased. In addition, the ApoB/ApoA1 mRNA level, which is a predictor of cardiovascular risk, was reduced in a time-dependent manner by UBR-W treatment. Macrophage-like cells (RAW 264.7) showed increased expression of ox-LDL-related genes, such as CD36, scavenger receptor-A, adipophilin, and PPAR-gamma, upon ox-LDL treatment compared to untreated control cells, and quantitative lipid analysis indicated a dramatic increase in lipid accumulation. However, UBR-W treatment significantly reduced expression of ox-LDL-related genes and largely prevented lipid accumulation. The results indicate that UBR-W mediates a cholesterol-lowering effect via inhibition of cholesterol synthesis and induction of LDL uptake through SREBP.

• Korean Journal of Food Science and Technology
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• v.47 no.3
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• pp.364-372
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• 2015

This study investigated the effects of fermented black raspberry (BR) and red ginseng (RG) extract co-treatment on lipid metabolism and obesity in rats fed with a high fat/high cholesterol diet (HFHCD) for 12 weeks. Compared to the corresponding values in rats fed with a HFHCD, total cholesterol and low-density lipoprotein (LDL)-cholesterol and triglyceride levels decreased whereas high-density lipoprotein (HDL)-cholesterol levels increased in rats treated with fermented BR and RG extracts. These extracts significantly increased the expression of HMG-CoA reductase, LDL receptor, and sterol regulatory-element-binding protein-2 (SREBP-2) mRNA, but decreased the mRNA expression of SREBP-1. Additionally the serum levels of leptin and fatty acid synthase were decreased. Moreover, supplementation with fermented BR and RG effectively increased fecal cholesterol excretion. These results suggest that fermented BR and RG extracts might be effective at preventing hypercholesterolemia and obesity.

• Atmosphere
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• v.28 no.1
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• pp.1-13
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• 2018

Characteristics of wind resources of offshore and coastal regions were compared using wind data obtained from HeMOSU-1 (Herald of Meteorological and Oceanographic Special Unit-1) meteorological mast located at Southwestern Sea, and ground-based LiDAR (Light Detection And Ranging) at Gochang observation site near it. The analysis includes comparison of basic wind statistics such as mean wind speed, wind direction, power law exponent and their temporal variability as well as site assessment items for the wind power plant such as turbulence intensity and wind power density at the two observation sites. It was found that the wind at HeMOSU-1 site has lower diurnal and seasonal variability than that at Gochang site, which lead to smaller turbulence intensity. Overall, the results of the comparative analysis show that the wind resource at HeMOSU-1 site located offshore has more favorable condition for wind power generation than the wind resource at Gochang which shows nature of coastal area.

• Journal of Plant Biotechnology
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• v.35 no.2
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• pp.163-167
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• 2008

Adventitious buds appeared within 2 weeks on the base of the petiole explants and increased for two months. A maximum of regeneration (15.6%) was obtained on the medium containing $1.5\;{\mu}M$ TDZ in combination with $1\;{\mu}M$ IBA. To know which explants are the best for the induction of regeneration, three explants such as leaf, petiole and leaf-petiole were used. Among the explant types, the leaf-petiole explant was significantly more effective than leaf and petiole for promoting adventitious shoots, with leaf-petiole inducing at the highest regeneration frequency (33.7%). The regeneration frequency of adventitious shoots in the leaf-petiole explants was significantly affected by leaf size and the position of explants. The leaf-petiole smaller than 5 mm leaf in width was induced at the highest regeneration frequency (68.9%). The smaller leaf sizes, the greater regeneration frequency. Also when the leaves are nearer to the shoot tip, the regeneration frequency is higher. When the rooted micro-shoots were transferred to the soil after growing for 6 weeks in the media, the survival rate was 90%.

• Journal of the Korean Society of Environmental Restoration Technology
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• v.24 no.4
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• pp.47-60
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• 2021

This study was conducted to classify quality attributes for quality elements of public service targeting Gochang Jayeonmadang and analyze their impact on resident satisfaction and dissatisfaction by each service quality element by using the Kano model and the customer satisfaction coefficient and dissatisfaction coefficient of Timko(1993). As a result of the study, all 20 quality elements of public service were classified as one-dimensional attributes. Since the Jayeonmadang project restores the damaged natural environment and restores the ecosystem, it is judged that satisfaction is proportionately satisfied as the natural environment has been restored and the ecosystem has been restored. According to Timko (1993)'s analysis of customer satisfaction coefficient, it is believed that the most effective way to improve residents' satisfaction is to carefully establish and implement maintenance plans and to create a good environment to ensure that plants have settled.

• Journal of the Korean earth science society
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• v.36 no.4
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• pp.341-350
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• 2015

This study is to explore geosites considering the geological characteristics in Gochang-gun and to investigate a possibility of being designated as the national geopark of Korea. In this study, the geosites within Gochang-gun are explored through literature search and field work. The results indicate that seven of the geosites in the Seonunsan area are relevant as potential national geopark, including Jinheunggul, Dosolam Maebulsang, Youngmungul, Nakjodae and Cheonmabong, Byungbawi, spherulitic rhyolite, and Dolmen site. In addition, there are other areas that have valus in terms of geological and educational aspect, including Hajeon mud flat and Myoungsasipri beach. The results of study imply that if various educational programs for the geotourism are properly developed, the Gochang-gun area has potential to be designated as the national geopark of Korea.

• Journal of the Economic Geographical Society of Korea
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• v.18 no.4
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• pp.522-538
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• 2015

The objective of this study was to review how contract farming started in Gochang-gun and identified its characteristics among the contracting parties and the consequent changes in the region's dairy industry with regard to the contract production of organic milk in Gochang-gun, Jeollabuk-do, Korea in conjunction with the Maeil Dairy Industry Corporation. The contract was established in keeping with the product diversification strategy of the company after a crisis due to opening of the market, taking advantage of the clean environment of Gochang-gun and positive attitudes of the local government and dairy farmers. The expansion of the participating farms led to a production gap among dairy farms in the region; however, the overall concern over the conventional practice of contract farming was mitigated as the organic farming spread with the conversion of the contract farms to organic farms.

• Journal of Korean Society of Rural Planning
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• v.28 no.1
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• pp.99-108
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• 2022

This study measured the importance and satisfaction of the values related to 'New Ruralism' using the IPA(Importance-Performance Analysis) technique by the rural leaders' group. In the result, the satisfaction value was evaluated lower in the importance of 'landscape and ecological resource conservation', 'settlement environment', and 'population' related items. On the other hand, the items of 'tourism resource management', 'landscape damage', and 'landscape and ecological resource conservation' showed high satisfaction. Therefore, the leaders' group of Gochang-gun perceived the importance of local tourism image, landscape damage prevention, settlement environment, and rural landscape in 'New Ruralism' management. However, the leaders' group valued lower in the items of population, ecological value and natural and historical tourist sites. This seems to be a characteristic of the leaders' group mainly engaged in agriculture. Through factor analysis, the six items excluded from the analysis were considered important factors in 'New Ruralism' in Gochang-gun through a review of previous studies. Still, the leaders' group of Gochang-gun did not recognize them as important items in the rural resource. However, these items will be able to contribute to the development of 'New Ruralism' in Gochang-gun, and it is necessary to improve the awareness of the leader group. Even if local governments or experts present an ideal goal for rural development, it is difficult to achieve the goals if there is a difference from the perception of residents. Therefore, it is important to understand the perception of 'New Ruralism' of the leaders' group who plays an important role in regional development projects.

• Journal of the Korean earth science society
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• v.37 no.2
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• pp.89-106
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• 2016

The Gochang open-coast intertidal flat is located in the southwestern coast of Korea (the eastern part of the Yellow Sea), characterized by macro-tidal range, an open-coast type, and sand substrates. This study has investigated seasonal variation in sedimentary facies of surface sediments in the Gochang intertidal flat. In the four seasons of February, May, August, and November, 2014, surface sediments of 252 sites in total were sampled and analyzed along three survey lines. The surface sediments of the Gochang intertidal flat in 2014 consisted mainly of fine-grained sand sediments showing a trend in grain size to be coarser in winter and finer in summer. Based on seasonal wave and tidal level data recorded near the study area, it was interpreted that the seasonal effects of wave were stronger than those of tide as a factor controlling surface sedimentation. High waves in winter resulted in the coarsening trend of grain size in surface sediments, whereas, during summer time, the sediments became finer by relatively low waves. Spatial sedimentary facies of the Gochang intertidal flat in 2014 represented that seasonal deviation of the upper tidal zone was larger than that of the lower tidal zone, hence sediments getting coarser in grain size and poorly sorted in the upper tidal zone. From upper to lower tidal zone, the grain size became finer and sediments were better-sorted, showing smaller seasonal deviations.

• Korean Journal of Food Science and Technology
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• v.45 no.5
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• pp.628-635
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• 2013

We investigated the effects of water extracts of unripe black raspberry (UBR) and red ginseng (RG) on cholesterol synthesis, 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase activity, and expression of low-density lipoprotein (LDL) or high-density lipoprotein (HDL)-related genes in HepG2 and Caco-2 (human hepatoma and intestinal cell lines, respectively). Our results showed that cholesterol synthesis and HMG-CoA reductase activity in HepG2 cells were inhibited by UBR and RG. Further, co-treatment with UBR and RG had a greater effect than did treatment with either UBR or RG. In Caco-2 cells, treatment with UBR and RG increased the expression of LDL-regulated genes, such as LDL receptor and SREBP-2, and also upregulated the level of HDL-associated ABCA1. Moreover, co-treatment with UBR and RG appeared to be more effective than treatment with either UBR or RG. Taken together, our results indicate that UBR and RG regulate the level of HDL-associated ABCA1 via signaling pathway, thereby preventing cholesterol synthesis.